Patent application number | Description | Published |
20080213096 | SEALING ELEMENT FOR USE IN A FLUID-FLOW MACHINE - A sealing element for sealing a component gap with respect to a flow, in particular for use in a fluid-flow machine, specifically in a turbomachine is provided. In addition a fluid-flow machine is provided including such a sealing element for sealing a component gap. The sealing element includes a hollow profile enclosing a cavity. Arranged in the hollow profile are a first opening and a second opening, which are spaced apart from each other in the longitudinal direction of the hollow profile. The first opening is formed as an inlet opening for a cooling fluid into the cavity of the hollow profile, the second opening is formed as an outlet opening for the cooling fluid from the cavity of the hollow profile. With the sealing element arranged in a fluid-flow machine, the sealing element can consequently be internally cooled by means of the cooling fluid. Furthermore, the sealing element uses the pressure gradient occurring in the flow in the direction of flow to form a stable cooling fluid flow. | 09-04-2008 |
20080230997 | Combustion chamber for a gas turbine - A combustion chamber for an industrial gas turbine has thermal protective elements which are installed along the inner circumference of its casing. The thermal protective elements are cooled by cooling air which is added to the fuel in the region in front of a front casing section after the cooling. A brush seal is installed between the front casing section and the thermal protective elements, where the brush seal is configured in segments. The combustion chamber can be sealed against leakages of cooling air in all operating states of the combustion chamber. | 09-25-2008 |
20090071167 | TURBOMACHINE, ESPECIALLY GAS TURBINE - A turbomachine with at least one combustion chamber and at least one turbine which lies downstream of it. The turbine has at least one support element and a lining element connected to the support element and formed as a heat shield. A gap sealed by means of a seal, is formed between the at least one combustion chamber and the turbine, an exchangeable insert is arranged in the gap on the end face on the support element and protects at least the support element against hot gases which penetrate into the gap, and against oxidation which is associated with it. | 03-19-2009 |
20090243221 | LEAF SEAL FOR A TURBOMACHINE - A leaf seal is provided for sealing a radial gap between a stator and rotor of a turbo machine. The seal includes a plurality of metallic sealing leaves, arranged in a row and attached to a carrier. The leaves are arranged concentrically around the circumference of the rotor and are arranged inclined at an angle to the radial direction of the rotor and in an opposite direction to the rotation direction and also includes front and rear plates connected to the carrier and extend over a circumference of the seal on both sides of the sealing leaves. A first axial distance is defined between the rear plate and the sealing leaves, and a second axial distance is defined between the front plate and the sealing leaves. An apparatus is also included for actively controlled variation of the first axial distance during operation of the turbomachine. | 10-01-2009 |
20090249792 | OPERATION OF A GAS TURBINE - Provided is a control method for a gas turbine plant having a first and a second combustors in series, such that combustion gases produced in the first combustor flows into the second combustor. The second combustor having a fuel lance with internal partitions, for injecting at least one fuel and a gas having a mixture of inert gas and support air into the second combustor. The partitions enable the gas to carry, and/or veil, at least one of the fuels as the fuel exits the lance. A variable of the second combustor is measured and the inert gas to support air mixture varies in response to variations of the variable so as to at least partially compensate for the operational effects of the variable on the operation of the second combustor. | 10-08-2009 |
20100313571 | GAS TURBINE - In a gas turbine, a plurality of burners, which are arranged concentrically to the rotational axis in a regular arrangement, each directing hot gas through an associated combustion chamber outlet into a turbine, at the inlet of which a second plurality of stator blades are arranged in a ring, uniformly spaced apart around the rotational axis. Cooling openings are provided, which are distributed over the circumference, through which cooling air is injected into the hot gas flow at the combustion chamber outlet. An improvement of the flow conditions in the hot gas is achieved by the cooling openings being divided into first cooling opening groups and second cooling opening groups. The arrangement of the first cooling opening groups corresponds to the arrangement of the stator blades, and in that the arrangement of the second cooling opening groups corresponds to the regular arrangement of the burners. | 12-16-2010 |
Patent application number | Description | Published |
20100074949 | Pharmaceutical composition and administration thereof - The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention. | 03-25-2010 |
20110021598 | CONTROLLED RELEASE FORMULATIONS - The invention relates to a controlled release formulation for an oral cytokine inhibitor of interleukin-1 beta converting enzyme. | 01-27-2011 |
20110064811 | Solid forms of N-[2,4-BIS(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline- -3-carboxamide - The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith. | 03-17-2011 |
20120214841 | SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE- -3-CARBOXAMIDE - The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith. | 08-23-2012 |
20120220625 | PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention. | 08-30-2012 |
20120258983 | Pharmaceutical Composition and Administrations Thereof - The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention. | 10-11-2012 |
20130274180 | Pharmaceutical Compositions - Forms and formulations of VX-950 and uses thereof. | 10-17-2013 |
20130317060 | Solid Forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline- -3-carboxamide - The present invention relates to solid state forms of N—[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith. | 11-28-2013 |
20140112988 | Pharmaceutical Composition and Administrations Thereof - The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention. | 04-24-2014 |
20140242172 | Solid Forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline- -3-carboxamide - The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith. | 08-28-2014 |
20140315948 | Pharmaceutical Composition and Administrations Thereof - The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention. | 10-23-2014 |
Patent application number | Description | Published |
20130224293 | PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions containing a solid dispersion of N—[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition. | 08-29-2013 |
20140255483 | PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition. | 09-11-2014 |
20150024047 | PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition. | 01-22-2015 |