Isakson
Andrew Patrick Isakson, Gibsonville, NC US
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20090100030 | CRIME INVESTIGATION TOOL AND METHOD UTILIZING DNA EVIDENCE - Crime investigation systems and methods including an investigation tool for receiving and storing DNA information, attaching related case information, disconnecting identification information, matching the information against stored information, and generating and communicating reports of match results, and an interface in communication with the crime investigation tool for entering the related case information, updating the information, and receiving the reports. The systems and methods further provide evidence chain of custody tracking and real time entry and updating from the field. | 04-16-2009 |
Brant E. Isakson, Charlottesville, VA US
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20150274779 | COMPOSITIONS AND METHODS FOR REGULATING ARTERIAL TONE - The present invention provides compositions and methods for regulating arterial tone based on the discovery herein of novel expression and regulation of hemoglobin alpha and cytochrome B5 reductase 3 and the effects on NO and NOS. | 10-01-2015 |
Cathy Lynn Isakson, Cincinnati, OH US
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20100187135 | Bag with Leak Resistant Features - A bag with flexible sidewalls defining an interior volume is provided with leak resistant features that function to absorb and retain liquids. These features include an absorbent-adhesive mixture that may be made from an adhesive and absorbent agents such as a super absorbent polymer. The absorbent-adhesive mixture can be applied on an inner surface of the flexible sidewalls in a location where it is likely to encounter liquids. The leak resistant features can also include a substrate that may be made from a non-woven material that is also applied to the inner surface of the sidewall and can be bonded to the sidewall by the absorbent-adhesive. In various embodiments, the bag can also include odor neutralizing features and/or configured with stretchable sidewalls. | 07-29-2010 |
John M. Isakson, Austin, TX US
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20090013206 | Efficient Utilization of a Multi-Source Network of Control Logic to Achieve Timing Closure in a Clocked Logic Circuit - A method, system, and computer program product are provided for achieving timing closure in a clocked logic circuit. For each local clock buffer in a set of local clock buffers, a logic synthesis tool determines a clock control signal input from a set of clock control signal inputs that will drive a clock control signal to the local clock buffer at a target frequency such that a first timing constraint may be met. The operation performed by the logic synthesis tool forms a determined clock control signal input. Responsive to the logic synthesis tool determining the determined clock control signal input, the logic synthesis tool couples the local clock buffer to the determined clock control signal input that drives the clock control signal to the local clock buffer at the target frequency to achieve timing closure in the clocked logic circuit. | 01-08-2009 |
20110004857 | LOGIC DIFFERENCE SYNTHESIS - A computer executed method is disclosed which accepts an original circuit with an original logic, accepts a modified circuit, and synthesizes a difference circuit. The difference circuit represents changes that implement the modified circuit's logic for the original circuit. The synthesis may locate an output-side boundary in the original logic in such a manner that the original logic is free of logic changes inbetween the output-side boundary and the primary output elements of the original circuit. The disclosed synthesis may also locate an input-side boundary in the original logic in such a manner that the original logic is free of logic changes inbetween the input-side boundary and the primary input elements of the original circuit. A computer program products are also disclosed. The computer program product contains a computer useable medium having a computer readable program code embodied therein. The computer readable program code when executed on a computer causes the computer to carry out the methods of finding input and output side boundaries in an original logic, and synthesizing inbetween those boundaries a difference circuit representing logic changes. | 01-06-2011 |
John Mack Isakson, Austin, TX US
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20080270955 | METHOD AND APPARATUS FOR MODIFYING EXISTING CIRCUIT DESIGN - The illustrative embodiments provide a computer implemented method and apparatus for modifying an existing circuit design. For a modification in a design of a circuit, the circuit design tool receives a code describing the modification, and a design of the circuit. The design of the circuit includes a first design, which includes a design for a number of metallic layers in the circuit. The design of the circuit further includes a second design, which includes and a design for a number of non-metallic layers in the circuit. The circuit design tool identifies a set of hooks, a set of disconnected components, and a set of filler cells in the design of the circuit. The circuit design tool produces a modification design, which is implemented in a revision of the first design, using the code, and one or more of the hooks, the disconnected components, and the filler cells. | 10-30-2008 |
Larry E. Isakson, Granger, IN US
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20110185887 | Self-Retaining End Cap for Braking Booster - A brake booster includes a housing configured for mounting to the master cylinder of a braking system. The housing defines a bore for receiving a power piston and an end cap, with a return spring disposed between the head of the piston and end cap. The housing and end cap define a recess and a rib sized to be received within the rib but configured for an interference fit between the end cap and housing outside the recess. The interference fit is calibrated to require a force to push the end cap into the bore that exceeds the force generated by the return spring when it is compressed between the end cap and the piston head. The recess and rib at least temporarily retains the spring within the bore until the brake booster is mounted to the master cylinder. | 08-04-2011 |
20110315008 | Pedal Rod Retaining Assembly for A Hydraulic Brake System - A braking system includes a brake booster with a power piston assembly structure defining a guide bore which possesses an open end, the guide bore defining a bore axis. A pivot structure is positioned in the guide bore and including (i) a body having an interior surface that defines a cavity, and (ii) a plurality of extensions protruding inwardly from the interior surface. A pedal rod includes (i) a ball-shaped distal end portion is retained in the cavity by the plurality of extension members, and (ii) a shaft extending from the ball-shaped distal end portion. A retainer is secured to the power piston assembly structure so as to prevent advancement of the pivot structure through the open end of the power piston assembly structure. The retainer defines a frusto-conical passageway through which the shaft extends enabling the shaft to pivot. | 12-29-2011 |
Peter Isakson, Southborough, MA US
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20150017095 | PROSTAGLANDIN E2 DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 01-15-2015 |
Peter C. Isakson US
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20120034160 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided. | 02-09-2012 |
Peter C. Isakson, Southborough, MA US
Patent application number | Description | Published |
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20090311253 | Dual Variable Domain Immunoglobulins and Uses Thereof - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 12-17-2009 |
20110212094 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 09-01-2011 |
20110250130 | TNF-ALPHA BINDING PROTEINS - Isolated binding proteins, e.g., antibodies or antigen binding portions thereof, which bind to tumor necrosis factor-alpha (TNF-α), e.g., human TNF-α, and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnostic methods for using the antibodies. | 10-13-2011 |
20120263722 | Dual Variable Domain Immunoglobulins and Uses Thereof - Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided. | 10-18-2012 |
20140219912 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided. | 08-07-2014 |
20140220019 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided. | 08-07-2014 |
20140234208 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided. | 08-21-2014 |
20140308286 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 10-16-2014 |
20140335014 | IL-1 ALPHA DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 11-13-2014 |