Patent application number | Description | Published |
20090186370 | DIAGNOSTIC BIOMARKERS FOR VASCULAR ANEURYSM - Biomarkers for diagnosis and monitoring of vascular aneurysms are described in the context of the use of assays to measure a plurality of these biomarkers. Tissue degeneration, particularly elastin and/or collagen degradation, can be monitored within patient blood (serum) and/or urine to diagnose the presence, the progression, or the likelihood of rupture of aneurismal disease. Additionally, enzymes responsible for this degradation and other biomarkers responsible for the activation or inhibition of these enzymes can be monitored additionally or alternatively. Prompt diagnosis can provide the opportunity for intervention and potentially increase the health of patients by tempering the development of debilitating and life-threatening vascular aneurysms. | 07-23-2009 |
20090214654 | TREATMENT OF ANEURYSM WITH APPLICATION OF CONNECTIVE TISSUE STABILIZATION AGENT IN COMBINATION WITH A DELIVERY VEHICLE - Delivery vehicles for controlled release of connective tissue stabilization agent for the treatment of vascular aneurysms are described. The delivery vehicle generally is combined with a connective tissue stabilization agent to form a therapeutic composition. The treatment of an aneurysm can be achieved through release of connective tissue stabilization agent from the delivery vehicle to the aneurysm. The connective tissue stabilization agent can be collagen stabilization agent, elastin stabilization agent, or a combination thereof. The aneurysm can be treated individually, simultaneously or sequentially with collagen stabilization agent and elastin stabilization agent embedded in separate delivery vehicles. | 08-27-2009 |
20100016833 | Devices for the Treatment of Vascular Aneurysm - Devices for the treatment of vascular aneurysms are described. The treatment is achieved through the delivery of an effective amount of elastin stabilization agent to an isolated volume at the aneurysm. The elastin stabilization agent maybe embedded in a delivery composition. The device optionally has an aspiration means to improve the effectiveness of the treatment. | 01-21-2010 |
20100119605 | COMPOSITIONS FOR TISSUE STABILIZATION - Collagen crosslinking/stabilization composition optionally in combination with elastin crosslinking composition as treatment of vascular aneurysms, methods of using the compositions, especially with respect to in vivo procedures are described. The treatment is achieved through the delivery of an effective amount of crosslinking/stabilization composition to the site of the aneurysm. The crosslinking/stabilization agent may be embedded in a delivery composition and delivered to the site of aneurysm using a delivery device. The site of the aneurysm may be isolated for treatment using the delivery device. The elastin stabilization agent may be simultaneously or sequentially delivered with the collagen crosslinking/stabilization agent for the treatment of vascular aneurysms in the isolated section of blood vessel. | 05-13-2010 |
20110093000 | VASCULAR MEDICAL DEVICES WITH SEALING ELEMENTS AND PROCEDURES FOR THE TREATMENT OF ISOLATED VESSEL SECTIONS - Devices for the isolation of a selected portion of a vessel are described. In some embodiments, the device comprises an introducer sheath and a sealing catheter that are movable relative to each other to create an isolated volume with adjustable size and location. The methods for the treatment of vascular aneurysms using the devices are described. The treatment is achieved through the delivery of an effective amount of stabilization agent to an isolated volume that encompass the aneurysm. The device optionally has an aspiration means to improve the effectiveness of the treatment. | 04-21-2011 |
20130245552 | VASCULAR MEDICAL DEVICES WITH SEALING ELEMENTS AND PROCEDURES FOR THE TREATMENT OF ISOLATED VESSEL SECTIONS - Devices for the isolation of a selected portion of a vessel are described. In some embodiments, the device comprises an introducer sheath and a sealing catheter that are movable relative to each other to create an isolated volume with adjustable size and location. The methods for the treatment of vascular aneurysms using the devices are described. The treatment is achieved through the delivery of an effective amount of stabilization agent to an isolated volume that encompass the aneurysm. The device optionally has an aspiration means to improve the effectiveness of the treatment. | 09-19-2013 |
Patent application number | Description | Published |
20100185272 | ELASTIN STABILIZATION OF CONNECTIVE TISSUE - A method and product are provided for the treatment of connective tissue weakened due to destruction of tissue architecture, and in particular due to elastin degradation. The treatment agents employ certain unique properties of phenolic compounds to develop a protocol for reducing elastin degradation, such as that occurring during aneurysm formation in vasculature. According to the invention, elastin can be stabilized in vivo and destruction of connective tissue, such as that leading to life-threatening aneurysms in vasculature, can be tempered or halted all together. The treatment agents can be delivered or administered acutely or chronically according to various delivery methods, including sustained release methods incorporating perivascular or endovascular patches, use of microsphere carriers, hydrogels, or osmotic pumps. | 07-22-2010 |
20120114732 | ELASTIN STABILIZATION OF CONNECTIVE TISSUE - A method and product are provided for the treatment of connective tissue weakened due to destruction of tissue architecture, and in particular due to elastin degradation. The treatment agents employ certain unique properties of phenolic compounds to develop a protocol for reducing elastin degradation, such as that occurring during aneurysm formation in vasculature. According to the invention, elastin can be stabilized in vivo and destruction of connective tissue, such as that leading to life-threatening aneurysms in vasculature, can be tempered or halted all together. The treatment agents can be delivered or administered acutely or chronically according to various delivery methods, including sustained release methods incorporating perivascular or endovascular patches, use of microsphere carriers, hydrogels, or osmotic pumps. | 05-10-2012 |
Patent application number | Description | Published |
20080252071 | Plug-In Connector for Medium Conduits - The invention relates to a plug-in connector ( | 10-16-2008 |
20100253067 | Preassembled Media Line - The present invention relates to a preassembled media line with a line connector, composed of a connector body with a connecting portion to which a media line is connected, and with a coupling portion for sealed connection to a mating coupling part. In this arrangement, the media line is provided with a heating wire and said heating wire is continued from the connector body and the media line, when connected, in such a manner that it is arranged at least partially on the coupling portion. The connector body and the media line are surrounded at the end by a housing formed, in particular, from housing shells, the sealing function and a retaining function being divided between the housing and the connector body. | 10-07-2010 |
20100263740 | Heatable Media Line - The present invention relates to an electrically heatable media line ( | 10-21-2010 |
20100290764 | LINE CONNECTOR FOR MEDIA LINES - The present invention relates to a line connector for media lines, consisting of a connector piece with at least one junction portion for junction connection to a media line or to an assembly and with a transitional portion contiguous to the junction portion and having a flow duct. In this case, at least in the region of the transitional portion, electrical heating means are provided in an arrangement at least partially surrounding the flow duct. Furthermore, the invention relates to a ready-made media line consisting of a pipeline with a heating conductor arranged on the circumference and with a heatable line connector fastened at least to one pipeline end of the media line. | 11-18-2010 |
20130163970 | HEATABLE MEDIUM PIPE AND METHOD FOR PRODUCING SAME - A heatable medium pipe having at least one pipe connector and heating element, wherein the heating element has a few wires, in particular two wires, and said wires extend continuously along the medium pipe and along the at least one pipe connector. In a method for producing such a heatable medium pipe, the heating element is continuously wound around a tubular medium pipe and the heating element is pre-assembled on the medium pipe in that the heating element is fastened or fixed by at least one fastening element, the medium pipe is cut to a first length for the particular application, the length corresponding to the desired medium pipe length (I | 06-27-2013 |
20130186484 | HEATABLE MEDIUM PIPE - For a heatable medium pipe having at least one pipe connector and heating element, wherein the heating element has a few wires, in particular one or two wires, wherein the wire(s) extend continuously along the medium pipe and along the at least one pipe connector. In a method for producing a heatable medium pipe, comprising the medium pipe, at least one pipe connector, a transition area between the medium pipe and the pipe connector, and at least one heating element, wherein the heating element has a few wires, in particular one or two wires, the medium pipe is pre-assembled with the at least one pipe connector, the wire or the few wires of the heating element are pre-assembled as a double-laid, one or two-part element or as an element connected to form a continuous part, the wire(s) are fastened on the outside of the pipe connector, transition area and medium pipe, and the ends of the wire(s) are guided into a feed-in connector for connecting to a current source or voltage source. | 07-25-2013 |
20130292935 | PREASSEMBLED MEDIA LINE - A preassembled line for axial engagement with a mating coupling part. The preassembled line includes a line connector having of a connector body with a connecting portion to which a media line is connected and also includes a coupling portion with sealing means for sealing relative to the mating coupling part. The media line is provided with a heating wire arranged on the coupling portion. The connector body, the media line and the heating wire being surrounded at one end by a housing that has a latching part for connecting with the mating coupling part. The latching part is formed on the housing portion surrounding the coupling portion. Sealing of the preassembled media line to the mating coupling part is separated from connecting of the preassembled media line to the mating coupling part and separately performed by the connector body and the housing. | 11-07-2013 |
20130330065 | HEATABLE FLUID LINE, USE THEREOF AND METHOD FOR PRODUCING SAME - A heatable fluid line having a pipeline and an electrical heat conductor extending at least over a section of the pipeline. The pipeline has at least two longitudinal sections that are configured differently in respect of the material properties and/or design thereof. At least one first longitudinal section is formed of a first material and a second longitudinal section is formed of a second material. The material of the second longitudinal section is more flexible and/or has a higher resilience than the material of the first longitudinal section. A described method for producing the fluid line relates to an adaptive attachment of the heat conductor on the outside of the pipeline that permits the heat conductor to be wound around fluid coupling and/or connector parts, in particular the housings by means of which the line is assembled, without strand separation. | 12-12-2013 |
20130333772 | FABRICATED MEDIA LINE AND USE IN AN SCR CATALYST SYSTEM - An assembled media line, or a section of a media line, for connecting a tank to a dosing unit in order to add a reducing agent into a SCR catalyst system of an internal combustion engine. The fluid line has electric heating in some sections for heating of the fluid. The fluid line is additionally provided, at least in some areas, with fluid tempering. In use, the media line connects a tank to a dosing unit in order to add a reducing agent in a SCR catalyst system of an internal combustion engine, and wherein the engine coolant is used as tempering fluid. The tempering is achieved by inclusion of at least one tempering line running alongside the fluid line. A line connector for such a media line includes a connecting housing in which the fluid line and two tempering lines can be connected. | 12-19-2013 |
20130336643 | LINE CONNECTOR FOR MEDIA LINES - A line connector having a connector piece with at least one junction portion for junction connection to a media line or to an assembly, a transitional portion contiguous to the junction portion, and a flow duct. In at least the region of the transitional portion, an electrical heating element for the media line is provided in an arrangement at least partially surrounding the flow duct. The connector piece, together with the heating element, is surrounded by an outer cladding. At least one of the junction portions is designed as a hollow, cylindrical receptacle for directly plugging in the end of the media line, the media line being capable of being fastened in a materially integral manner. The junction portion including, at least in regions, a material transparent to laser beams in such a way that the media line can be fastened by way of laser welding. | 12-19-2013 |
20140321841 | ASSEMBLED HEATABLE MEDIA LINE COMPRISING A MEDIA LINE HAVING AT LEAST TWO HEATING ELEMENTS ARRANGED ON THE EXTERIOR THEREOF, AND METHOD FOR THE PRODUCTION THEREOF - An assembled heatable media line having a media line having at least two heating elements arranged on the exterior of the media line and at least one line connector. In order to heat the at least one line connector, only one of the heating elements is arranged at or on said line connector and at least partially surrounds the same. A method for producing a heatable media line comprising the media line, at least one line connector and at least two heating elements is disclosed. The media line is pre-assembled, the heating elements being continuously wound around the media line. The heating elements are fastened or fixed on the media line by at least one fastener. The media line is cut to a first length depending on the desired used, said length corresponding to the desired media line length (IR) plus an allowance length (Iz) which carries the heating element length (IM) required for winding the heating element around the at least one line connector and a transition region between the media line and the line connector, the fastener is removed in the media line section corresponding to the allowance length (Iz), the heating element is wound off from the media line section corresponding to the allowance length (Iz), the media line is cut to the desired media line length (IR) to give a second media line section, one of the heating elements is shortened prior to or after the second cutting step performed on the media line, the second media line section is connected to the at least one line connector, and the heating element that has not been shortened is wound around the at least one line connector. | 10-30-2014 |
20140366974 | ASSEMBLED HEATABLE MEDIA LINE COMPRISING A MEDIA LINE HAVING AT LEAST TWO HEATING ELEMENTS ARRANGED ON THE EXTERIOR THEREOF, AND METHOD FOR THE PRODUCTION THEREOF - A heatable media line having at least one media line with two connector ends, in particular line connectors, and at least two electrical heating elements. At least one element is provided by which a differentiated heat input and/or output is enabled or provided for at both connector ends of the heatable media line. | 12-18-2014 |