Patent application number | Description | Published |
20100076340 | DEVICE AND METHOD TO EXTRACT MATERIAL OF A MATERIAL RESERVOIR - A device to extract material of a material reservoir has at least one guide tube with internal space and with an inner wall surrounding the internal space; at least one sled that can implement a sled translation movement in the inner space along a longitudinal alignment of the guide tube; and at least one collection unit with collection surface to collect the material. The collection unit and the sled are coupled to one another such that the sled translation movement of the sled leads to a collection translation movement of the collection surface of the collection unit, and such that the collection surface can be inserted into the material reservoir and be withdrawn from the material reservoir. A rotation mechanism that is operated manually or automatically can be provided with which a wire, which acts as a collection device, can be displaced in vivo over a length of 1 mm to up to 2 cm within a venous cannula. The invention is used in medical technology, for example, to collect cells from a reservoir in the form of a bodily fluid. | 03-25-2010 |
20100106039 | Unknown - Example embodiments relate to a device for measuring nitrogen monoxide in exhaled air by a gas sensor unit with at least one gas sensor. A device and/or method for oxidation of nitrogen monoxide to nitrogen dioxide may be included. The device and/or method for oxidation of nitrogen monoxide to nitrogen dioxide includes a non-consuming catalyst for catalyzing the oxidation of nitrogen monoxide to nitrogen dioxide. | 04-29-2010 |
20100143919 | In vitro assay for early diagnosis of diabetes mellitus type 1 - An in vitro assay is disclosed for early diagnosis of insulin-dependent diabetes mellitus type 1. In at least one embodiment, the assay includes i) determining susceptibility markers for diabetes mellitus type 1 in a biological sample from a symptom-free individual; ii) determining inflammatory markers in the same or in a further biological sample from the individual; iii) determining the presence or the risk of developing insulin-dependent diabetes mellitus type 1 on the basis of the values obtained in i) and ii); and, possibly, iv) performing step ii) after a defined time interval or v) performing an imaging method for the pancreas. At least one embodiment is further directed to the use of this assay for monitoring the progression of a diabetes mellitus type 1 disease. | 06-10-2010 |
20100174505 | Conditioned medical testing - The invention refers to a computer implemented method, a computer system a test machine and a computer program product for executing conditioned and qualified test. An ordering instance may order a set of tests, comprising an initial test and a set of follow-up tests, wherein the execution of each of the follow-up tests is dependent of the result of the respective predecessor test, like the initial test. The conditions for executing the follow-up tests are dynamically definable and are analyzed automatically. | 07-08-2010 |
20100174555 | System for automatic clinical pathway optimization - At least one embodiment of the present invention refers to a method, a system, a computer readable medium and/or a computer program product for optimizing a clinical pathway. The clinical pathway includes a sequence of actions. In at least one embodiment, he method aims at finding the best suitable and optimal following action for a respective action. There is provided a set of rules, patient information data and optimization criteria. After having received a symptom or an action there is deduced a set of possible following actions. After having deduced all possible following actions, these possible following actions are evaluated by the optimization criteria. After evaluation the optimal following action is suggested as a result. | 07-08-2010 |
20100317960 | THERMOTHERAPY DEVICE AND METHOD TO IMPLEMENT THERMOTHERAPY - A thermotherapy device has a transmitter, a receiver and a processing unit. The transmitter is designed to emit a high-energy radiation in a treatment region of a patient. The high-energy radiation exhibits a power that is suitable for thermotherapy. The receiver is designed to detect a sound signal that is generated by the treatment region depending on the high-energy radiation radiated into said treatment region. The processing unit is coupled with the transmitter) and the receiver. The processing unit automatically determines information about the treatment region depending on the detected sound signal. | 12-16-2010 |
20100331833 | IN-VITRO DEVICE MONITORING DURING MINIMALLY INVASIVE ABLATION THERAPY - A method and apparatus for monitoring and controlling interventional therapy is described, where the interventional therapy results in the destruction of tissue and the release of chemical markers. When interventional therapy results in destruction of a patient tissue, such as cancerous tissue, a variety of chemical markers may be released into the bloodstream. An in-vitro diagnostic (IVD) device may be used to measure the concentration of an analyte representing a marker and compare the measured concentration with a predetermined set point so as to monitor or control the procedure. The blood for the analysis may be obtained either inter-procedurally or intra-procedurally depending on the promptness of the effect being measured and the speed of measurement. | 12-30-2010 |
20110046497 | SENSOR PLATFORM FOR RESPIRATORY GAS ANALYSIS - An appliance is disclosed for measuring at least one gas analyte in exhaled air. In at least one embodiment, the appliance includes an inlet opening for the introduction of exhaled air (mouthpiece), at least one measuring chamber for receiving a sensor unit, and a conduit which provides a fluid connection from the opening to the measuring chamber, and wherein, depending on the gas analyte that is to be measured, a sensor unit with a suitable gas sensor can be introduced into the receiver. | 02-24-2011 |
20110072883 | MULTIFUNCTIONAL CONTROL VALVE FOR GAS MEASUREMENT INSTRUMENTS - A multifunctional control valve for gas measurement instruments, e.g., for respiratory gas analysis, is disclosed. In at least one embodiment, the multifunctional control valve includes a first inlet opening, an outlet opening, a main line, and a bypass line, wherein a measurement chamber is in the main line, wherein the measurement chamber is arranged downstream of a first multiway valve which can selectively connect the main line or the bypass line with the inlet opening, and wherein the measurement chamber is arranged upstream of a second multiway valve which can selectively connect the main line or the bypass line with the outlet opening. | 03-31-2011 |
20110076684 | APPARATUS AND METHOD FOR ACQUIRING, DETECTING, AND ANALYZING CELLS IN A MICROFLUIDIC SYSTEM - An apparatus is disclosed for acquiring, detecting, and, optionally, analyzing cells in a biological liquid, which apparatus has a microfluidic system. In at least one embodiment, the apparatus includes at least one microfluidic channel having a small cross-section which is completely or partially coated with cell-specific binding molecules and which has no flow obstacles dividing the fluid flow; at least one apparatus for generating a steady and alterable liquid flow through the microfluidic channel, and optionally at least one apparatus for analyzing the genetic information of the cell. In at least one embodiment, the method includes a sample of a biological liquid being conducted through an apparatus defined above at a defined velocity V | 03-31-2011 |
20110076754 | DEVICE AND METHOD FOR FILTERING ONE OR MORE PARTICLES TO BE DETECTED FROM A FLUID - A device is disclosed for filtering a particle to be detected from a fluid. In at least one embodiment, the device includes a substrate and, applied above it, a protective layer, a channel being disposed between them for the purpose of receiving a fluid containing different particles. In at least one embodiment, the channel extends at least partially in a spiral shape between its inlet and outlet and on its internal wall contains a coating for attracting a particle type to be filtered, which coating is applied at least on the radially outside subsection of the internal wall of the channel. Owing to the laminar longitudinal movement of the fluid inside the channel a radially outward directed centrifugal force acts on the particles, with the result that per time unit more particles come into contact with the radially outside subsection of the internal wall of the channel than the radially inside subsection of the internal wall of the channel. The filter effect is reinforced as a result. | 03-31-2011 |
20110077544 | METHOD FOR OPTIMIZING THE GAS CONVERSION RATE IN A RESPIRATORY GAS ANALYZER - A method for optimizing a gas conversion rate in a respiratory gas analyzer, more particularly for nitric oxide (NO) in the respiratory gas, and an associated device are disclosed. | 03-31-2011 |
20110092853 | INTERVENTION DEVICE FOR COLLECTING BIOLOGICAL MATERIAL AND METHOD FOR THE PRODUCTION THEREOF - An intervention device is disclosed for collecting biological material comprises a surface with a coating covering the surface at least in part. In at least one embodiment, capture molecules, by which the biological material can be bound, are immobilized on the coating. The capture molecules are distributed stochastically on the coating. | 04-21-2011 |
20110313257 | Method for Recording and Evaluation of Measurements Related to the Condition of a Patient for Configuration of a Portable, Patient-Controlled Device Operated to Record Said Measurements and Related Device - In a method for recording and evaluating measurements related to the condition of a patient for configuration of a portable, patient-controlled device operated to record the measurements,—at least one measurement describing the condition of the patient is recorded by the device,—the measurement and/or at least one parameter derived therefrom is/are transferred to an evaluation device via a communication connection,—the measurement and/or the parameter is/are evaluated by or on the evaluation device by an expert system and/or an expert to determine patient-specific information,—configuration data ascertained in consideration of the patient-specific information is transferred back to the device via the or another communication connection, and—the device is configured according to the configuration data. | 12-22-2011 |
20120021435 | DETECTION OF LIVING, CIRCULATING, OR DISSEMINATED CELLS OR CELL CONSTITUENTS IN BLOOD OR BONE MARROW FOLLOWING FILTRATION OF BLOOD - A method is disclosed for detecting circulating cells in a body fluid sample. In at least one embodiment, the method includes: filtering the body fluid sample through a porous membrane; transferring the porous membrane with the cells located thereon as filter residue to a cell culture vessel, wherein one surface of the cell culture vessel is coated with a first antibody which is directed to a first cell-specific marker; incubating the porous membrane in the cell culture vessel with a cell culture medium, wherein cell-specific markers released by any cells present are bound by the first antibody to produce a bound first cell-specific marker on the surface coated with the first antibody; removing the porous membrane with the cells located thereon as filter residue from the cell culture vessel; detecting the bound first cell-specific marker on the surface coated with the first antibody. | 01-26-2012 |
20120046963 | METHOD, EVALUATION UNIT AND MEDICAL EXPANSION APPARATUS TO DETERMINE AND INVOICE THE USE OF THE MEDICAL EXPANSION APPARATUS - In a method to determine and invoice the use of a medical expansion apparatus provided to a user (in particular a service provider) by an owner (in particular a referring physician), the medical expansion apparatus expanding the functionality of a primary medical apparatus, the following steps can be implemented automatically by an evaluation unit. Data describing the usage of the expansion apparatus and/or measurement signals from which the usage data are derived are received from the expansion apparatus and/or the primary apparatus. The usage data are evaluated to create an invoice, in particular a cost calculation. The invoice is sent to the owner and/or the user, in particular to processing devices and/or program means associated with the user and/or the owner. | 02-23-2012 |
20120065535 | GAS ANALYSIS APPARATUS HAVING A COMBINATION OF GAS DEHUMIDIFIER AND GAS CONVERTER - An apparatus for measuring nitrogen monoxide in exhaled air by way of a gas sensor unit ( | 03-15-2012 |
20120150040 | APPARATUS, SYSTEM, AND METHOD FOR ADAPTIVELY CONTROLLING A FRAME INTERVAL BETWEEN ULTRASOUND SCANNING FRAMES FOR AN ULTRASOUND ELASTICITY IMAGING SCAN - An apparatus, system and method for adaptively controlling a frame interval between ultrasound scanning frames of an ultrasound elasticity imaging scan. The system includes a transmitter for transmitting ultrasound beams to a subject during an ultrasound elasticity imaging scan, and a receiver for receiving ultrasound beam echoes from the subject responsive to transmitted ultrasound beams. The system also includes a processor for processing a plurality of the ultrasound beam echoes to determine a strain variation of the tissue undergoing strain, calculating a value for an ultrasound scanning frame interval adapted for imaging the tissue undergoing the determined strain variation, and setting the value of the ultrasound scanning frame interval for acquiring ultrasound elasticity images of the tissue undergoing the determined strain variation. | 06-14-2012 |
20120290321 | Computer implemented compensation for medical services - A computer implemented method and system for compensating costs for medical services are provided. The system has at least three actors, a compensation unit, a referring computer and a service computer for executing the medical service ordered by the referring computer. After receiving a medical report as result of the medical services rendered, the referring computer is an evaluation unit for accessing quality of the medical service. Evaluation data are transmitted to the compensation unit for computation of compensation for the medical service taken into account the evaluation data for accessing quality of the medical service. | 11-15-2012 |
20120315664 | ASSEMBLY AND METHOD FOR THE FILTRATION OF A LIQUID AND USE IN MICROSCOPY - An assembly and method are disclosed for the filtration of a liquid and the use thereof, wherein a supporting body is designed in a recess of a carrier and a filter membrane lies flat on the supporting body. The filter membrane and the supporting body are designed to be permeable to liquids and thus serve as filters, in particular for filtering tumor cells from blood. The carrier can having standard shapes of an object carrier for microscopy and the filtration residue on the filter membrane can be easily handled and examined in the microscope. As a result of the filter membrane lying level on the supporting body, the filtration residue can be particularly well examined microscopically. | 12-13-2012 |
20130063141 | APPARATUS AND METHOD FOR IDENTIFYING MAGNETICALLY MARKED MICRO OBJECTS - An apparatus is disclosed for identifying magnetically marked micro objects, in particular biological micro objects, preferably tumor cells. In at least one embodiment, the apparatus includes a carrier for at least one micro object; a device for applying a region with a magnetic gradient field, wherein the gradient field comprises at least one zero point; a device for applying the micro object with a high frequency magnetic field, in particular at the site of the zero point; a device for relative movement of the carrier and region to one another; a device for receiving a change in a magnetic flux through the micro object; a device for evaluating the received change in the magnetic flux and for identifying the position of the micro object; and a device for in particular automatically analyzing the micro object. | 03-14-2013 |
20130075286 | SAMPLE CARRIER AND METHOD FOR MICROSCOPIC EXAMINATION OF BIOLOGICAL SAMPLES - A sample carrier for microscopic examination of biological samples includes a base body and a filter membrane. The base body has at least one recess in which the filter membrane is disposed. The filter membrane makes an essentially flush closure with the surface of the sample carrier. The sample carrier has a circular shape. | 03-28-2013 |
20140106355 | ARRANGEMENT AND PROCESS FOR OPTICAL ANALYSIS AND SPECIFIC ISOLATION OF BIOLOGICAL SAMPLES - A process is disclosed for detecting cells in a liquid sample, which includes: i) filtration of the liquid sample through a porous membrane which is suitable for retaining detectable cells, where at least one subregion of a support is configured as transparent supporting body and the membrane is arranged over its area on the transparent supporting body in such a way that detectable cells are retained on at least part of the surface of the membrane and that at least part of the sample liquid passes through the membrane, ii) application of a liquid optical medium which has essentially the same refractive index as the supporting body, and iii) optical measurement of at least a subarea of the membrane in order to detect detectable cells. | 04-17-2014 |
20140106388 | AUTOMATED CTC DETECTION - An embodiment relates to a method and to an array for detecting live circulating or disseminated cells in body fluids (for example blood, urine) or tissue samples (for example bone marrow) mixed with liquid. The method includes: a) filtering the liquid sample through a porous membrane that is suitable for retaining cells to be detected, such that cells to be detected come to rest upon at least a part of the surface of the membrane and the sample liquid passes the membrane; b) applying a first process liquid containing a first agent for marking the cells to be detected with a first marker; c) incubating the process liquid on the membrane for a predetermined time period, wherein the cells to be detected are marked; and d) detecting the marked cells to be detected on the surface of the membrane. | 04-17-2014 |
20140109648 | Operating Method for a Gas Sensor and Gas Sensor - The disclosure relates to an operating method for a gas sensor, in particular a gas sensor for detecting asthma. According to said method, nitrogen monoxide or nitrogen dioxide is detected in a measuring phase and the gas sensor is heated by a heating device in a desorption phase in order to accelerate desorption. The heating process is continued until the temporal alteration of the measuring signal of the gas sensor falls below a threshold value. | 04-24-2014 |
20140110349 | ASSEMBLY AND METHOD FOR FILTRATION - An assembly and a method for filtration are disclosured, which are suitable in particular for the filtration of cells, for example tumor cells, from a sample, for example a blood sample. In the method, a pressure differential between the pressure upstream and the pressure downstream of a filter is determined; and the pressure differential between upstream and downstream of the filter is adjusted such that the pressure differential does not exceed a predetermined value. | 04-24-2014 |