Koonce, US
Chad Koonce, Madison, WI US
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20130029368 | METABOLIC MATURATION IN STEM CELL-DERIVED TISSUE CELLS - The present invention concerns methods and compositions for promoting a conversion in stem cells or cells derived therefrom from glycolysis to aerobic respiration and its associated pathways, including oxidative phosphorylation, the TCA cycle, fatty acid oxidation, and pyruvate decarboxylation, for example. In specific embodiments, certain media is employed to improve metabolic maturation of particular stem cell-derived cells, including human embryonic stem cells and human induced pluripotent stem cells, for example. Particular media comprises media without glucose or optionally without pyruvate, with fatty acids, with L-carnitine, with taurine, creatine, non-essential amino acids, L-glutamine, and with anti-oxidants or free-radical scavengers, for example. | 01-31-2013 |
David Koonce, Santa Clara, CA US
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20150375358 | CHAMBER COMPONENTS WITH POLISHED INTERNAL APERTURES - Disclosed herein are systems and methods for polishing internal surfaces of apertures in semiconductor processing chamber components. A method includes providing a ceramic article having at least one aperture, the ceramic article being a component for a semiconductor processing chamber. The method further includes polishing the at least one aperture based on flowing an abrasive media through the at least one aperture of the ceramic article, the abrasive media including a polymer base and a plurality of abrasive particles. | 12-31-2015 |
David Koonce, San Mateo, CA US
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20100180426 | PARTICLE REDUCTION TREATMENT FOR GAS DELIVERY SYSTEM - Methods and apparatus for reducing particles in a gas delivery system are provided herein. In some embodiments, a method of fabricating a gas distribution apparatus, such as a gas distribution plate or nozzle, for a semiconductor process chamber includes providing a gas distribution apparatus having one or more apertures adapted to flow a gas therethrough. A slurry is flowed through the one or more apertures to remove a damaged surface from sidewalls of the plurality of apertures. In some embodiments, the gas distribution apparatus may be oxidized before or after flowing the slurry through the one or more apertures. In some embodiments, the gas distribution apparatus may be conditioned by providing RF power to the gas distribution plate for a desired period of time. | 07-22-2010 |
David M. Koonce, Cypress, TX US
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20110007472 | CABLE MANAGEMENT MODULE - A cable management module having of a first module capable of connecting to a hard disk drive drawer; a second module releasably connected to the first module. A plurality of pairs of connecting arms connect the first module to the second module with each of the pairs of connecting arms being pivotally joined to each other at an intermediate point. A catch member is located on at least one side of the first module and a locking release mechanism is attached to the second module and to a locking member capable of engaging the catch member. A method for accessing a hard disk drive without disconnecting input/output cables and a method of replacing the input/output cables is also disclosed. | 01-13-2011 |
20150062789 | SERVER ADAPTER - An adapter ( | 03-05-2015 |
20150092788 | INPUT-OUTPUT MODULE - A base circuit board ( | 04-02-2015 |
Gene Koonce, Greeley, CO US
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20080297293 | MULTI-FREQUENCY ELECTROMAGNETIC FIELD GENERATOR - Disclosed is a multi-frequency electromagnetic field generator that is capable of generating electromagnetic flux fields that are projected at a distance from the device. Radial fields, horizontal fields and spiral fields are generated by the electromagnetic field generator and are projected at a distance from the device. A wide range of frequencies is generated as a result of the fast rise time pulses produced by the device. The geometry and structure of the device cause the electromagnetic fields to encircle the device and be collected at the far end of the device by an antenna. An inner coil antenna, that is centrally disposed in the device, receives electromagnetic waves that are transformed into a current that is applied to an inner coil. The inner coil produces a strong electromagnetic field that extends outwardly in a horizontal direction that increases the projected horizontal distance of the electromagnetic field. | 12-04-2008 |
J. Michael Koonce, San Francisco, CA US
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20150308622 | MOBILE COMPRESSED GAS REFUELER - A fully contained, mobile, compressed natural gas (CNG), compressed breathing air, or other compressed gas refueling unit, and methods of use of said refueling unit, that use a pneumatically powered booster pump to provide a consistent, high pressure filling of CNG storage tanks without using an external power source. | 10-29-2015 |
John Koonce, Naples, FL US
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20130134175 | SELF-CLOSING CAP - A sealing lid assembly used in connection with a service port, the sealing lid assembly including a cap; a plug extending from an underside of the cap and at least partially receivable in the service port, a first seal supported on the plug and extending radially outward therefrom to sealingly engage the service port when the cap is in a closed position; and a biasing assembly adapted to urge the cap toward the closed position. | 05-30-2013 |
John R. Koonce, Naples, FL US
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20140026990 | TANK MODULE INTERFACE FOR FLUID RESERVOIRS - The combination of a reservoir having an interface defining an aperture, the interface including a wall extending into the reservoir, the reservoir having a recessed groove in an upper surface about the aperture, the recessed groove including a plurality of recesses thereon: a head unit having an exterior shape complementary to the shape of the aperture, the head unit being positioned within the aperture; the head unit having an inwardly extending rim corresponding to the aperture circular wall, the head unit including a lug, the head unit lug engaging one of recesses, the head unit having a seai ring about an outer periphery of the head unit inwardly extending rim, the sea! ring engaging the aperture wall and the head unit inwardly extending rim. | 01-30-2014 |
John Ross Koonce, Naples, FL US
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20120103433 | MULTI-MODE HEATER FOR A DIESELEMISSION FLUID TANK - A heater assembly used in connection with a diesel emissions fluid tank in a vehicle, the heater assembly including a first heater connectable to an alternating current power supply; a second heater connectable to a direct current power supply within the vehicle; wherein the first heater is adapted to operate at a higher power than the second heater; wherein the first heater is closer to the tank than the second heater; a temperature sensor in sensing communication with the tank and adapted to provide a tank temperature; a control circuit connected to the second heater and the vehicle power supply, wherein the temperature sensor communicates the tank temperature to the control circuit, wherein the control circuit selectively activates the second heater to obtain a desired tank temperature. | 05-03-2012 |
Judy A. Koonce, Sachse, TX US
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20110055217 | SYSTEM TO MODIFY WEBSITES FOR ORGANIC SEARCH OPTIMIZATION - A system is configured to modify a website to optimize the website for an organic search of a topic. The system includes a data management module configured to receive search terms for the topic, receive related terms to the search terms for the topic, and receive website input data. The system also includes a scanning module configured to scan and index web pages and web objects in the website and identify a subset of web pages and web objects associated with the search terms and the related terms. The system also includes an optimizing module configured to process the subset of web pages and web objects from the website by prioritizing the subset of web pages and web objects or measuring a metric with respect to the subset of web pages and web objects. The search terms and related terms are deployed into the subset of web pages and web objects on the website based on the processing. | 03-03-2011 |
20130191364 | SYSTEM TO MODIFY A WEBSITE FOR SEARCH OPTIMIZATION - A system to optimize a website for a search of a topic includes a processor, a memory, and instructions to cause the processor to receive at least one term related to the topic, and to receive web objects pertaining to the website to be optimized. The system is to calculate at least one metric pertaining to the at least one term and the web objects. | 07-25-2013 |
Kenneth L. Koonce, Baton Rouge, LA US
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20100016227 | LIGAND/LYTIC PEPTIDE COMPOSITIONS AND METHODS OF USE - Amphipathic lytic peptides are ideally suited to use in a ligand/cytotoxin combination to specifically inhibit cells that are driven by or are dependent upon a specific ligand interaction; for example, to induce sterility or long-term contraception, or to attack tumor cells, or to selectively lyse virally-infected cells, or to attack lymphocytes responsible for autoimmune diseases. The peptides act directly on cell membranes, and need not be internalized. Administering a combination of gonadotropin-releasing hormone (GnRH) (or a GnRH agonist) and a membrane-active lytic peptide produces long-term contraception or sterilization in animals in vivo. Administering in vivo a combination of a ligand and a membrane-active lytic peptide kills cells with a receptor for the ligand. The compounds are relatively small, and are not antigenic. Lysis of gonadotropes has been observed to be very rapid (on the order of ten minutes.) Lysis of tumor cells is rapid. The two components—the ligand and the lytic peptide—may optionally be administered as a fusion peptide, or they may be administered separately, with the ligand administered slightly before the lytic peptide, to activate cells with receptors for the ligand, and thereby make those cells susceptible to lysis by the lytic peptide. The compounds may be used in gene therapy to treat malignant or non-malignant tumors, and other diseases caused by clones or populations of “normal” host cells bearing specific receptors (such as lymphocytes), because genes encoding a lytic peptide or encoding a lytic peptide/peptide hormone fusion may readily be inserted into hematopoietic stem cells or myeloid precursor cells. | 01-21-2010 |
Michael Koonce, San Francisco, CA US
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20080227924 | Process and System Using Nitrogen Trifluoride to Fluorinate Plastic - Process and systems for the treatment of plastic with flourine proximally generated from nitrogen trifluoride decomposition. | 09-18-2008 |
Michael Sean Koonce, St. Louis, MO US
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20120166583 | SEMANTIC INFORMATION PROCESSING - A system for exchanging various forms of information between computer-executable agents. A computing device is configured to determine semantic data associated with each data object (DO) of a plurality of DOs. Each DO is associated with a location, and the semantic data describes the content of the associated DO. The computing device receives, from a first user computing device, a request for DO information and, in response to the request, provides DO information including the locations and the semantic data associated with the retrieved DOs to the user computing device by (a) transmitting the locations and the semantic data to the first user computing device, and/or (b) instructing the first user computing device to request the DO information from a second user computing device to which the locations and the semantic data were previously transmitted. | 06-28-2012 |
Nathan A. Koonce, Little Rock, AR US
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20150141875 | COMPOSITIONS AND METHODS FOR NON-INVASIVE DETECTION AND TREATMENT OF HYPOXIC CELLS IN VIVO - Compositions and methods used in the non-invasive detection and/or treatment of hypoxic tissues in vivo are described. Compositions including microbubbles functionalized with one or more hypoxia targeting agents and one or more therapeutic compounds, methods of preparing the functionalized microbubbles, and methods of using the functionalized microbubbles for diagnostic and/or therapeutic applications are described, including a method for selectively determining the amount of vascular hypoxia occurring in a tissue. | 05-21-2015 |
Ryan Michael Koonce, Austin, TX US
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20130013393 | SYSTEMS AND METHOD FOR IDENTIFYING OFFERED INCENTIVES THAT WILL ACHIEVE AN OBJECTIVE - A computer implemented method of improving the performance of a viral marketing program comprises exposing, via a computer network, a first offered incentive to a first plurality of users. A first consumer viral marketing action is to be completed to receive the first incentive. First data indicative of the first plurality of users' progress toward achieving the first action is collected thereby providing a likelihood of the first incentive obtaining an objective. A second incentive is exposed to a second plurality of users. A second consumer viral marketing action is to be completed to receive the second incentive. Second data indicative of the second plurality of users' progress toward achieving the second marketing action is collected thereby providing a likelihood of the second incentive obtaining the objective. The first and second data is compared using a metric to identify which incentive is more likely to obtain the objective. | 01-10-2013 |
20130268350 | System and Method for Optimization of Viral Marketing Efforts - Systems and methods for optimizing viral marketing efforts are disclosed in which a trial a viral marketing trial program is presented to a user. The viral marketing trial program includes a user incentive as well as a plurality of user tasks that needs to be completed to receive the user incentive. One or more user reactions to the plurality of user tasks are monitored; user feedback in accordance with the one or more user reactions is collected, the user feedback is analyzed using one or more metrics and the viral marketing trial program is adjusted in accordance with the analyzed user feedback. | 10-10-2013 |
William A. Koonce, Pearland, TX US
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20100178502 | LOW VOLATILES COATINGS, SEALANTS AND BINDERS FROM RENEWABLE OILS - A composition comprises (a) a binder component which comprises (1) 5 to 100 weight percent of at least one natural oil derived polyol having at least about 50 percent primary hydroxyl groups and (2) sufficient additional polyol different from a natural oil derived polyol to make 100 percent wherein the natural oil derived polyol has an average of from 1.5 to 3 hydroxyl groups per molecule and an equivalent weight of from 200 to 5000; and (b) a crosslinking component reactive with hydroxyl groups. Furthermore, a process for producing a coating, adhesive, binder or combination thereof on the surface of a substrate, comprises in any order: (a) admixing binder and crosslinking components of a composition to form an admixture, wherein a binder component comprises (1) 5 to 100 weight percent of at least one natural oil derived polyol having at least about 50 percent primary hydroxyl groups and (2) sufficient additional polyol different from a natural oil derived polyol to make 100 percent wherein the natural oil derived polyol has an average of from 1.5 to 3 hydroxyl groups per molecule and an equivalent weight of from 200 to 5000; and (b) applying a layer of said admixture on said surface. The invention includes coatings, adhesives, binders and combinations thereof prepared from any composition of the invention, substrates coated by the process of the invention or coated using a composition of the invention and articles, including laminates, comprising a coating, adhesive, binder or combination thereof of the invention. | 07-15-2010 |
20100249357 | ROOM TEMPERATURE CURABLE POLYMERS AND PRECURSORS THEREOF - A polyester polyol, referred to hereinafter as a MHMS polyol comprises fatty acid based mer units wherein at least about 80 weight percent of the fatty acid based mer units are from methyl 9 (10) hydroxymethylstearate, or is prepared from an oil having fatty acids or fatty acid esters which are at least about 80 weight percent oleic acid or esters thereof and which has an average hydroxyl functionality of from 1.5 to 4. A reaction product, referred to herein after as MHMS alkoxysilane prepolymer, is produced from at least one such MHMS polyol and at least one isocyanate functional silane. The prepolymer is moisture cured to form a silylated MHMS polymer. The process of preparing a MHMS polyol comprises (A) reacting a fatty acid ester wherein at least about 80 weight percent of the fatty acid esters are methyl 9 (10) hydroxymethylstearate, or are prepared from an oil having fatty acids or fatty acid esters which are at least about 80 weight percent oleic acid or esters thereof with an initiator having at least 2 reactive groups selected from primary hydroxyl groups, amine groups, terminal isocyanate groups, terminal carbonyl groups or a combination thereof. The process of preparing at least one MHMS alkoxysilane prepolymer comprises steps of: (a) supplying at least one MHMS polyol; (b) supplying at least one isocyanate functional silane and (c) admixing the MHMS polyol and isocyanate functional silane or combination thereof, optionally in the presence of at least one catalyst to produce at least one MHMS alkoxysilane prepolymer. A process of preparing at least one silylated MHMS polymer comprises steps of: (a) supplying at least one MHMS alkoxysilane prepolymer; and (b) exposing it to moisture under conditions such that at least one silylated MHMS polymer is formed. Articles comprising the polyol, prepolymer, or polymer include elastomers, sealants, adhesives, coatings and the like. | 09-30-2010 |
20100266799 | PREPOLYMERS AND POLYMERS FOR ELASTOMERS - A prepolymer or elastomer is the reaction product of reactants (a) at least one polyester polyol or fatty acid derived polyol which is the reaction product of at least one initiator and a mixture of fatty acids or derivatives of fatty acids comprising at least about 45 weight percent monounsaturated fatty acids or derivatives thereof, (b) optionally, at least one polyol which is different from the polyol of (a); and (c) at least one isocyanate compound (herein after isocyanate) having an average of at least about 1.8 isocyanate groups per molecule. A process comprises admixing reactants (a) at least one polyol composition comprising the fatty acid derived polyol which is the reaction product of at least one initiator and a mixture of fatty acids or derivatives of fatty acids comprising at least about any of 45 weight percent monounsaturated fatty acids or derivatives thereof; and (b) at least one isocyanate having an average functionality of at least about 1.8 under reaction conditions to form a reaction product which is an elastomer or prepolymer is formed therefrom. An article, coating or thermoplastic polyurethane comprises the elastomer is formed from the prepolymer of or using the process of the invention. | 10-21-2010 |
20110015292 | PREPOLYMERS MADE FROM NATURAL OIL BASED POLYOLS - A prepolymer and products made from the preopolymer is described. The prepolymer includes the reaction product of at least one isocyanate and at least one natural oil based polyol. The natural oil based polyol includes at least two natural oil moieties separated by a molecular structure having an average of at least about 19 ether groups between any 2 of the natural oil moieties or by a polyether molecular structure having an equivalent weight of at least about 480. | 01-20-2011 |
20120253001 | Polyurethane-Based Sealant for Insulated Glass Units - Insulated glass units are sealed with polyurethane made using a natural oil-based polyol (NOBP). In one embodiment the NOBP is made using a monol-rich monomer containing high levels of mono-hydroxy functional fatty acid methyl esters. Insulated glass sealants based on these compounds provide enhanced resistance to UV and oxidative degradation as compared to conventional products while still providing the required barrier and mechanical properties. | 10-04-2012 |
20130060000 | METHODS FOR PRODUCING CROSSLINKABLE SILYL GROUP-CONTAINING POLYOXYALKYLENE POLYMERS - Embodiments of the invention provide for a method of producing a silylated polyoxyalkylene polymer having at least one crosslinkable silyl group and at least one hydroxyl group in each molecule. The method comprises providing a polyoxyalkylene polymer having at least one unsaturated group and at least one alcoholic hydroxyl group in each molecule, wherein the polyoxyalkylene polymer includes an impurity double metal cyanide complex mixed therein, and wherein the polyoxyalkylene polymer has not been treated with a metal-coordinating compound; and adding to the polyoxyalkylene polymer a compound having a hydrogen-silicon bond and a crosslinkable silyl group in each molecule and a hydrosilylation catalyst to thereby carry out a hydrosilylation reaction, wherein the hydrosilyation reaction is performed in an absence of a metal-coordinating compound. | 03-07-2013 |
20130090429 | LOW VISCOSITY SILYL-TERMINATED POLYMERS - Embodiment of the invention provide for compositions having at least one crosslinkable silyl group in each molecule. The crosslinkable silane-terminated polymer may include a reaction product of at least a polyol having a nominal functionality of at least 2 and a isocyanate capped hydrosilylated polymer. The isocyanate capped hydrosilylated polymer may include a reaction product of at least one isocyanate and a hydrosilylated polymer. The hydrosilylated polymer may include a reaction product of a the reaction of at least a) a polymer having at least one unsaturated group and at least one alcoholic hydroxyl group in each molecule and having a number average molecular weight of between about 100 and about 5000 and b) a compound having a hydrogen-silicon bond and a crosslinkable silyl group in each molecule. | 04-11-2013 |
20130096251 | CURABLE SILYL POLYMERS - Embodiments of the invention relate to crosslinkable silyl group-containing polymers and methods of producing them. In one embodiment a method of producing a silyl polymer is provided. The method includes reacting at least one natural oil based polyol with at least one isocyanate to form at least one prepolymer having at least one NCO group. The at least one natural oil based polyol includes the reaction product of hydroxymethylated fatty acids or esters thereof and at least one polyol initiator. The prepolymer having at least one NCO group is reacted with at least one amino functional alkoxy silane to form the silyl polymer, such that the silyl polymer includes at least one crosslinkable silyl group, at least one urethane group, and at least one urea group in each molecule. | 04-18-2013 |
20130096252 | TIN FREE SILYL-TERMINATED POLYMERS - Embodiments of the invention provide for methods of producing a composition comprising a crosslinkable silane-terminated polymer having at least one crosslinkable silyl group in each molecule. The method comprises providing a polymer having at least one unsaturated group and at least one alcoholic hydroxyl group in each molecule, adding to the polymer a compound having a hydrogen-silicon bond and a crosslinkable silyl group in each molecule and a hydrosilylation catalyst to thereby carry out a hydrosilylation reaction to form a composition comprising hydrosilylated polyoxyalkylene polymers, reacting the hydrosilylated polyoxyalkylene polymers with at least one isocyanate in the presence of a first tin-free catalyst to form an isocyanate reacted hydrosilylated polymer, and optionally reacting the isocyanate reacted hydrosilylated polymer with a polyol having a nominal functionality of at least 2 to form a polyol reacted crosslinkable silane-terminated polymer. | 04-18-2013 |
20130096274 | SILYL-TERMINATED POLYMERS - Embodiments of the invention provide for compositions including a crosslinkable silane-terminated polymer having at least one crosslinkable silyl group in each molecule. The crosslinkable silane-terminated polymer comprises a reaction product of at least a isocyanate capped hydrosilylated polymer and a polyol having a nominal functionality of at least 2 which is at least one of a polycarbonate polyol, a natural oil based polyol, a polyoxyalkyleneamine, a difunctional aromatic amine, a polybutyloxide polyether polyol, and a polytetramethylene glycol. | 04-18-2013 |
20140100348 | PROCESS FOR MAKING LOW VISCOSITY, FAST CURING SILANE TERMINATED POLYMERS - Methods of producing a composition comprising a crosslinkable silane-terminated polymer having at least one cross-linkable silyl group in each molecule are provided. The method may comprise providing a polymer having at least one unsaturated group and at least one alcohol hydroxyl group in each molecule and having a number average molecular weight between about 100 and about 5,000, adding to the polymer a compound having a hydrogen-silicon bond and a crosslinkable silyl group in each molecule and a hydrosilylation catalyst to thereby carry out a hydrosilylation reaction to form a composition comprising hydrosilylated polymers, wherein the hydrosilylation reaction has a hydrosilylation efficiency greater than 50% as determined by | 04-10-2014 |
20140179815 | METHOD FOR PREPARING FLEXIBLE POLYURETHANE FOAM WITH HYDROLYSABLE SILANE COMPOUNDS - Flexible polyurethane foams are made using certain hydrolysable silane compounds in the foam formulation. The hydrolysable silane compounds contain at least one isocyanate-reactive group and at least one hydrolysable silane group. The presence of the hydrolysable silane compound in the foam formulation leads to improved tensile, tear and elongation properties without an adverse effect on other important foam properties such as resiliency and hysteresis loss. | 06-26-2014 |
20140309372 | SILANE TERMINATED POLYMER FOR COATING, ADHESIVES, SEALANT AND ELASTOMER APPLICATIONS - A copolymer-filled crosslinkable silane-terminated polymer having at least one crosslinkable silyl group in each molecule is provided. The copolymer-filled crosslinkable silane-terminated polymer is the reaction product of a copolymer-filled polyol and an isocyanate capped hydrosilylated polymer. The isocyanate capped hydrosilylated polymer is the reaction product of at least one isocyanate and a hydrosilylated polymer. The hydrosilylated polymer is the reaction product of a polymer having at least one unsaturated group and at least one alcoholic group in each molecule and a compound having a hydrogen-silicon bond and a crosslinkable silyl group in each molecule. The copolymer-filled crosslinkable silane-terminated polymers exhibit improved modulus and tensile strength properties while maintaining elongation properties. | 10-16-2014 |
20150031815 | ESTER CARBONATE POLYOLS FOR HYDROLYTICALLY STABLE ADHESIVES - A two-component curable adhesive or sealant composition is provided. The first component may comprise a mixture of at least one polyol selected from the group comprising a polyester polyol, a polyester-polycarbonate copolymer polyol, and combinations thereof, a resin, and optionally a solvent. The second component may comprise a prepolymer obtained by reacting a polyester-polycarbonate copolymer polyol which is the reaction product of a polyester polyol which is the reaction product of one or more organic acids, and one or more glycols having a functionality of two or more and one or more polycarbonate polyols, at least one organic polyisocyanate component, and at least one chain extending agent and optionally a solvent. Alternatively, the first component may comprise a polyester-polycarbonate copolymer polyol, a resin, and optionally a solvent. The second component may comprise a polyisocyanate curative and optionally a solvent. The cured adhesive exhibits improved hydrolytic properties while maintaining excellent processability and adhesive properties. | 01-29-2015 |
20150218428 | POLYURETHANE BASED INSULATED GLASS SEALANT - Embodiments of the invention provide for polyurethane-based sealants. The sealants include a reaction product of a reaction system which includes at least one isocyanate, and at least one polyester polyol. The polyester polyol includes a reaction product of a polyester reaction mixture which includes one or more hydrophobic monomers, one or more organic diacids or methyl esters thereof, and one or more diols. | 08-06-2015 |
William Aaron Koonce, Pearland, TX US
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20130066023 | REACTIVE ISOCYANATE-TERMINATED PREPOLYMERS FOR BINDER APPLICATIONS - Elastomer composites are prepared by wetting particles of a natural or synthetic rubber with a liquid one-component moisture-curable resin composition and then exposing the wetted particles to moisture to cure the resin composition. The moisture-curable resin composition comprises (a) an isocyanate-terminated polyurethane prepolymer having an isocyanate content of from 0.5 to 12% by weight and (b) from 1 to 30%, based on the combined weight of components (a) and (b), of an epoxide or lactone compound having a molecular weight of from about 70 to about 1000 and which is miscible in the prepolymer at the relative proportions thereof that are present. In addition, the composition contains no more than 0.1% by weight of compounds having a primary or secondary amino group. | 03-14-2013 |