Patent application number | Description | Published |
20100317732 | METHOD OF INHIBITING ABCG2 AND OTHER TREATMENT METHODS - Disclosed are methods of enhancing the chemotherapeutic treatment of tumor cells, reducing resistance of a cancer cell to a chemotherapeutic agent, a method of inhibiting ABCG2, Pgp, or MRP1 in a mammal afflicted with cancer, and a method of increasing the bioavailability of an ABCG2 substrate drug in a mammal. The methods comprise administering effective amounts of certain compounds to the mammal, for example, a compound of the formula (I): Formula (I), wherein R | 12-16-2010 |
20130274323 | METHOD OF INHIBITING ABCG2 AND OTHER TREATMENT METHODS - Disclosed are methods of enhancing the chemotherapeutic treatment of tumor cells, reducing resistance of a cancer cell to a chemotherapeutic agent, a method of inhibiting ABCG2, Pgp, or MRP1 in a mammal afflicted with cancer, and a method of increasing the bioavailability of an ABCG2 substrate drug in a mammal. The methods comprise administering effective amounts of certain compounds to the mammal, for example, a compound of the formula (I): | 10-17-2013 |
Patent application number | Description | Published |
20100029827 | POLYOLEFIN COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME - The invention provides a composition comprising at least one olefin multi-block interpolymer; at least one functionalized olefin-based polymer; and optionally at least one thermoplastic polyurethane. The invention also provides for articles prepared from the inventive compositions and for methods for making the same. | 02-04-2010 |
20100093942 | FUNCTIONALIZED OLEFIN POLYMERS, COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHOD OF MAKING THE SAME - In one aspect the invention provides a melt process for preparing a functionalized olefin multiblock interpolymer, said process comprising grafting onto the backbone of the olefin multiblock interpolymer at least one compound comprising at least one “amine-reactive” group to form a grafted olefin multiblock interpolymer, and reacting a primary-secondary diamine or an alkanolamine with the grafted olefin multiblock interpolymer, without the isolation of the grafted olefin multiblock interpolymer. | 04-15-2010 |
20100143651 | FUNCTIONALIZED OLEFIN POLYMERS, COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME - The invention provides polyolefin blend compositions of polar and/or non-polar polymers, with at least one functionalized polyolefin polymer selected from the group consisting of: amine functionalized, hydroxyl functionalized, imide functionalized, anhydride functionalized, or carboxylic acid functionalized polyolefin polymers. The invention also provides methods for making the functionalized polyolefin polymer. The invention also provides for materials and articles containing at least one component prepared from such compositions. | 06-10-2010 |
20130059989 | Polyolefin Compositions and Articles Prepared Therefrom, and Methods for Making the Same - The invention provides a composition comprising at least one olefin multi-block interpolymer; at least one functionalized olefin-based polymer; and optionally at least one thermoplastic polyurethane. The invention also provides for articles prepared from the inventive compositions and for methods for making the same. | 03-07-2013 |
20130338316 | FUNCTIONALIZED OLEFIN POLYMERS, COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME - In one aspect the invention provides a melt process for preparing a functionalized olefin multiblock interpolymer, said process comprising grafting onto the backbone of the olefin multiblock interpolymer at least one compound comprising at least one “amine-reactive” group to form a grafted olefin multiblock interpolymer, and reacting a primary-secondary diamine or an alkanolamine with the grafted olefin multiblock interpolymer, without the isolation of the grated olefin multiblock interpolymer. | 12-19-2013 |