Patent application number | Description | Published |
20080261868 | Methods and Compositions for Treating Diabetes - The instant invention provides a method of treating an animal suffering a disease characterized by excessive apoptosis by administering a therapeutically effective amount of at least one serine protease inhibitor and thereafter monitoring a decrease in apoptosis. The inhibitor of the invention includes α | 10-23-2008 |
20080261869 | COMPOSITIONS AND METHODS OF USE FOR ALPHA-1 ANTITRYPSIN HAVING NO SIGNIFICANT SERINE PROTEASE INHIBITOR ACTIVITY - Embodiments herein illustrate methods and compositions for treating medical disorders. In certain embodiments, compositions and methods relate to reducing, inhibiting or treating a bacterial infection, or a viral infection in a subject. More particularly, embodiments herein relate to compounds including naturally occurring and synthetic compositions having alpha-1 antitrypsin activity but no significant serine protease inhibitor activity. | 10-23-2008 |
20090118162 | INHIBITORS OF SERINE PROTEASE ACTIVITY AND THEIR USE IN METHODS AND COMPOSITIONS FOR TREATMENT OF GRAFT REJECTION AND PROMOTION OF GRAFT SURVIVAL - Embodiments of the present invention illustrate methods of treating and preventing transplantation and side effects associated with transplantation. In particular, the present invention relates to compositions and methods for inhibition of graft rejection and promotion of graft survival. Thus, the invention relates to modulation of cellular activities, including graft rejection, promotion of graft survival, graft versus host rejection and conditions commonly associated with graft rejection. More particularly, the present invention relates to the inhibitory compounds comprising naturally occurring and man-made inhibitors of serine protease and inducers of other alpha1-antitrypsin activities. | 05-07-2009 |
20090203580 | Compositions and methods of use for alpha-1 antitrypsin having no significant serine protease inhibitor activity - Embodiments herein illustrate methods and compositions for treating medical disorders. In certain embodiments, compositions and methods relate to reducing, inhibiting or treating graft rejection, transplant rejection or diabetes in a subject. Other embodiments herein relate to compounds including naturally occurring and synthetic mutant compositions of alpha-1 antitrypsin, wherein the alpha-1 antitrypsin has no significant serine protease inhibitor activity. | 08-13-2009 |
20090220518 | METHODS AND COMPOSITIONS FOR TREATMENT OF GRAFT REJECTION AND PROMOTION OF GRAFT SURVIVAL - Embodiments herein illustrate methods of treating, reducing or preventing transplantation rejection and/or side effects associated with transplantation. Some embodiments relate to compositions and methods for inhibition of graft rejection and promotion of graft survival. Other embodiments relate to modulation of cellular activities, including graft rejection, promotion of graft survival, graft versus host rejection and conditions commonly associated with graft rejection. Yet other embodiments relate to the inhibitory compounds comprising naturally occurring and man-made inhibitors of serine protease, derivatives and fragments of the carboxy-terminus of alpha1-antitrypsin and inducers of other alpha1-antitrypsin activities and uses thereof. | 09-03-2009 |
20090298747 | Methods and Compositions For Treatment of Nitric Oxide-Induced Clinical Conditions - The present invention provides compositions and methods for modulating cellular nitric oxide (NO) production and for treating a clinical condition associated therewith. | 12-03-2009 |
20100137192 | COMPOSITIONS AND METHODS FOR TREATING OR AMELIORATING MYCOBACTERIAL INFECTIONS - A novel method of treating and preventing bacterial diseases is provided. In particular, the present invention relates to compositions and methods for inhibition of Gram negative, Gram poitive and acid fast bacilli in general and tuberculosis (TB), | 06-03-2010 |
20100144630 | Compositions, methods and uses for inhibition and/or treatment of influenza infection - Embodiments of the present invention illustrate methods and compositions for treating medical disorders. In certain embodiments, compositions and methods relate to reducing or inhibiting onset, transmission or development of a viral disorder. | 06-10-2010 |
20100210528 | Compositions, methods and uses for inhibition and/or treatment of influenza infection - Embodiments of the present invention illustrate methods and compositions for treating medical disorders. In certain embodiments, compositions and methods relate to reducing or inhibiting a the onset or development of a viral disorder. | 08-19-2010 |
20110021416 | COMPOSITIONS, METHODS AND USES FOR TREATING BACTERIAL INFECTIONS - A novel method of treating and preventing bacterial diseases is provided. In particular, the present invention relates to compositions and methods for inhibition of Gram negative, Gram positive and acid fast bacilli in general and tuberculosis (TB), | 01-27-2011 |
20110201587 | HSP90 INHIBITORS AND METHODS OF USE - The present invention provides methods for treating various clinical conditions associated with biological activity of HSP90 in a subject. Such methods include administering to the subject in need of such a treatment a therapeutically effective amount of a composition comprising an HSP90 inhibitor. | 08-18-2011 |
20110319330 | Methods For Treating Arthritis, Autoimmune Disease, and Ischemia-Reperfusion Injury - The instant invention provides a method of treating an animal suffering a disease characterized by excessive apoptosis by administering a therapeutically effective amount of at least one serine protease inhibitor and thereafter monitoring a decrease in apoptosis. The inhibitor of the invention includes α | 12-29-2011 |
20120040913 | METHODS AND COMPOSITIONS FOR TREATING DIABETES - The instant invention provides a method of treating an animal suffering a disease characterized by excessive apoptosis by administering a therapeutically effective amount of at least one serine protease inhibitor and thereafter monitoring a decrease in apoptosis. The inhibitor of the invention includes α | 02-16-2012 |
20120045417 | METHODS AND COMPOSITIONS FOR ISLET CELL PRESERVATION - Embodiments of the present invention illustrate methods of treating and preventing transplantation and side effects associated with transplantation. In particular, the present invention relates to compositions and methods for inhibition of graft rejection and promotion of graft survival. Thus, the invention relates to modulation of cellular activities, including graft rejection, promotion of graft survival, graft versus host rejection and conditions commonly associated with graft rejection. More particularly, the present invention relates to the inhibitory compounds comprising naturally occurring and man-made inhibitors of serine protease and inducers of other alpha 1-antitrypsin activities. | 02-23-2012 |
20120045460 | METHODS AND COMPOSITIONS FOR TREATMENT OF GRAFT REJECTION AND PROMOTION OF GRAFT SURVIVAL - Embodiments of the present invention illustrate methods of treating and preventing transplantation and side effects associated with transplantation. In certain embodiments, compositions and methods relate to inhibition of graft rejection and promotion of graft survival. Thus, the invention relates to modulation of cellular activities, including graft rejection, promotion of graft survival, graft versus host rejection, islet cell preservation and conditions commonly associated with graft rejection. Other embodiments relate to the inhibitory compounds comprising naturally occurring and man-made inhibitors of serine protease and inducers of other alpha1-antitrypsin activities. | 02-23-2012 |
20120071545 | COMPOSITIONS AND METHODS FOR TREATMENT OF BACTERIAL AND MYCOBACTERIAL INFECTIONS - A novel method of treating and preventing bacterial diseases is provided. In particular, the present invention relates to compositions and methods for inhibition of Gram negative, Gram positive and acid fast bacilli in general and tuberculosis (TB), | 03-22-2012 |
20120225813 | COMPOSITIONS, METHODS AND USES FOR TREATMENT OF TYPE 1 DIABETES - Embodiments herein concern compositions and methods for treating diabetes in a subject. | 09-06-2012 |
20140234310 | COMPOSITIONS AND METHODS FOR TREATMENT OF BACTERIAL AND MYCOBACTERIAL INFECTIONS - A novel method of treating and preventing bacterial diseases is provided. In particular, the present invention relates to compositions and methods for inhibition of Gram negative, Gram positive and acid fast bacilli in general and tuberculosis (TB), | 08-21-2014 |
20140370036 | COMPOSITIONS OF, AND METHODS FOR, ALPHA-1 ANTITRYPSIN FcFUSION MOLECULES - A novel method of treating and preventing bacterial diseases is provided. In particular, the present invention relates to compositions and methods for inhibition of Gram negative, Gram positive and acid fast bacilli in general and tuberculosis (TB), | 12-18-2014 |