Letourneur
Didier Letourneur, Rixheim FR
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20100267989 | CONTINUOUS PREPARATION OF AMINES BY NITRILE COMPOUND HYDROGENATION - Amino compounds are continuously prepared by hydrogenation of nitrile compounds in the presence of a catalyst, and more particularly diamines are prepared by the continuous hydrogenation of dinitrile compounds in the presence of a Raney metal catalyst and in the absence of an alcoholic solvent; the subject process includes extracting a portion of the catalyst present in the reaction medium, the extracted portion of the catalyst is submitted to a regeneration for providing a catalyst having a catalytic activity lower than that of a fresh catalyst but still high and the regenerated catalyst is recycled to the reaction medium together with fresh catalyst according to a predetermined ratio, whereby the consumption of catalyst is reduced per ton of amines produced. | 10-21-2010 |
20100292511 | PURIFICATION OF IMPURE HEXAMETHYLENEDIAMINES - Impure hexamethylenediamines and more particularly those hexamethylenediamines containing contaminating amounts of tetrahydroazepine (THA), or more generally contaminating amounts of imines, are purified by distillation carried out with a short retention time of the impure hexamethylenediamine in the distillation column; the hexamethylenediamine obtained has a very low concentration of THA. | 11-18-2010 |
20110230681 | METHOD FOR PRODUCING AMINES - Amine compounds, more particularly diamine compounds, are prepared by hydrogenating compounds including nitrile functions. The preparation can include the use of a hydrogenation catalyst, adapted for the hydrogenation of nitrile compounds into amine compounds, including Raney nickel as well as iron, chromium, and zinc as doping elements. | 09-22-2011 |
Didier Letourneur, Chatenay Malabry FR
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20100221301 | Method for Preparing Porous Scaffold for Tissue Engineering - The present invention relates to a method for preparing a porous scaffold for tissue engineering. It is another object of the present invention to provide a porous scaffold obtainable by the method as above described, and its use for tissue engineering, cell culture and cell delivery. The method of the invention comprise the steps consisting of a) preparing an alkaline aqueous solution comprising an amount of at least one polysaccharide and one cross-linking agent b) freezing the aqueous solution of step a) c) sublimating the frozen solution of step b). characterized in that step b) is performed before the cross-linking of the polysaccharide occurs in the solution of step a). | 09-02-2010 |
20100221303 | Method for Preparing Porous Scaffold for Tissue Engineering, Cell Culture and Cell Delivery - The present invention relates to a method for preparing a porous scaffold for tissue engineering. It is another object of the present invention to provide a porous scaffold obtainable by the method as above described, and its use for tissue engineering, cell culture and cell delivery. The method of the invention comprises the steps consisting of: a) preparing an alkaline aqueous solution comprising an amount of at least one polysaccharide, an amount of a cross-linking agent and an amount of a porogen agent b) transforming the solution into a hydrogel by placing said solution at a temperature from about 4° C. to about 80° C. for a sufficient time to allow the cross-linking of said amount of polysaccharide and c) submerging said hydrogel into an aqueous solution d) washing the porous scaffold obtained at step c). | 09-02-2010 |
Didier Letourneur, Lyon FR
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20100130789 | PRODUCTION OF AMINES BY HYDROGENATION OF NITRILE COMPOUNDS - A method for producing amines by the hydrogenation of nitrile compounds in the presence of a catalyst, notably a method for producing diamines by the continuous hydrogenation of dinitrile compounds in the presence of a Raney-metal catalyst, includes controlling the molar flow of nitrile compounds and the mass flow of catalyst in a hydrogenation piston reactor in order to minimize the occurrence of impurities and deterioration of the catalyst. | 05-27-2010 |
Didier Letourneur, Paris FR
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20130171126 | CROSSLINKED POLYSACCHARIDE BEADS AND THEIR BIOMEDICAL USES - The present inventions relates to beads as biocompatible material adapted for use within the human or animal body. Said beads are highly useful for tissue engineering, in situ tissue regeneration, as well as for drug and/or cells delivery. In addition, said beads may support biotechnological applications such as cell carriers. | 07-04-2013 |
20130224277 | POROUS POLYSACCHARIDE SCAFFOLD COMPRISING NANO-HYDROXYAPATITE AND USE FOR BONE FORMATION - The present invention relate to three dimensional porous polysaccharide matrices able to induce mineralisation of a tissue in osseous site, as well as in non-osseous site, in the absence of stem cells or growth factors. | 08-29-2013 |
20150064110 | CROSSLINKED POLYSACCHARIDE BEADS COMPRISING AN IMAGING AGENT - The present invention relates to a method for preparing beads comprising imaging agent. The present invention further provides beads highly useful for medical imaging. | 03-05-2015 |
20150087056 | CRYOPRESERVATION OF CELLS, TISSUES AND ORGANS - The present invention provides a method for cryoprotecting a biological specimen comprising the step of freezing said biological specimen in the presence of a hydrogel and in the absence of cryoprotectant. | 03-26-2015 |
Didier Letourneur, Paris Cedex FR
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20120093725 | Fucoidans as Ligands for the Diagnosis of Degenerative Pathologies - The present invention relates to the diagnosis of clinical conditions characterized by undesirable and/or abnormal selectin expression. In particular, the invention provides for the use of fucoidans for the detection of selectins using imaging techniques including ultrasonography, scintigraphy and MRI. Selectin-targeted imaging agents are provided that comprise at least one fucoidan moiety associated with at least one detectable moiety. Methods and kits are described for using these imaging agents in the diagnosis of clinical conditions such as thrombosis, myocardial ischemia/reperfusion injury, stroke and ischemic brain trauma, neurodegenerative disorders, tumor metastasis and tumor growth, and rheumatoid arthritis. | 04-19-2012 |
20120183475 | Fucoidans as Ligands for the Diagnosis of Degenerative Pathologies - The present invention relates to the diagnosis of clinical conditions characterized by undesirable and/or abnormal selectin expression. In particular, the invention provides for the use of fucoidans for the detection of selectins using imaging techniques including ultrasonography, scintigraphy and MRI. Selectin-targeted imaging agents are provided that comprise at least one fucoidan moiety associated with at least one detectable moiety. Methods and kits are described for using these imaging agents in the diagnosis of clinical conditions such as thrombosis, myocardial ischemia/reperfusion injury, stroke and ischemic brain trauma, neurodegenerative disorders, tumor metastasis and tumor growth, and rheumatoid arthritis. | 07-19-2012 |
20140134102 | Fucoidans as Ligands for the Diagnosis of Degenerative Pathologies - The present invention relates to the diagnosis of clinical conditions characterized by undesirable and/or abnormal selectin expression. In particular, the invention provides for the use of fucoidans for the detection of selectins using imaging techniques including ultrasonography, scintigraphy and MRI. Selectin-targeted imaging agents are provided that comprise at least one fucoidan moiety associated with at least one detectable moiety. Methods and kits are described for using these imaging agents in the diagnosis of clinical conditions such as thrombosis, myocardial ischemia/reperfusion injury, stroke and ischemic brain trauma, neurodegenerative disorders, tumor metastasis and tumor growth, and rheumatoid arthritis. | 05-15-2014 |
Francois Letourneur, Sainte Foy Les Lyon FR
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20120034229 | MONOCLONAL ANTIBODIES DIRECTED AGAINST LG4-5 DOMAIN OF ALPHA3 CHAIN OF HUMAN LAMININ-5 - The present invention relates to a monoclonal antibody binding to the LG4/5 domain of chain alpha3 of human protein laminin-5, wherein said monoclonal antibody inhibits the binding of syndecan-1 to said laminin-5 alpha3 chain LG4/5 domain, in particular 1H12 monoclonal antibody produced by the hybridoma cell line named 1H12 deposited on Jan. 8, 2008 at the C. N. C. M. under number 1-3890, as well as chimerized, humanized derivatives and fragments thereof, and nucleic acid sequences encoding them, as well as vectors and host cells expressing them. The invention further relates to the medical application of such antibodies, in particular for treating cancer. | 02-09-2012 |
Hervé Letourneur, Mountain View, CA US
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20100312952 | Multiprocessor System Having an Input/Output (I/O) Bridge Circuit for Transferring Data Between Volatile and Non-Volatile Memory - A disclosed circuit includes circuitry for coupling to a volatile memory, circuitry for coupling to a nonvolatile NAND flash memory, and circuitry that: (i) receives a volatile memory request from a processor and satisfies the volatile memory request by accessing the volatile memory, and (ii) receives a nonvolatile NOR flash memory read request from the processor and satisfies the NOR read request by accessing both the NAND flash memory and the volatile memory. The circuit may also include circuitry that receives a volatile memory request from another processor and satisfies the volatile memory request from the other processor by accessing the volatile memory, and circuitry that receives a NAND flash memory read request from the other processor and satisfies the NAND read request by accessing the NAND flash memory. Multiprocessor systems including the circuit are described, as is a method for satisfying a NOR flash memory read request. | 12-09-2010 |
20120084470 | Utilitzing USB Resources - At least one downstream interface may be configured to be simultaneously connected to both a USB 3.0 compliant device and a USB 2.0 compliant device. The interface may be used for communicating with a USB 3.0 compliant device via a downstream port and simultaneously communicating with a USB 2.0 compliant device via the downstream port. | 04-05-2012 |
20130145056 | UTILIZING USB RESOURCES - At least one downstream interface may be configured to be simultaneously connected to both a USB 3.0 compliant device and a USB 2.0 compliant device. The interface may be used for communicating with a USB 3.0 compliant device via a downstream port and simultaneously communicating with a USB 2.0 compliant device via the downstream port. | 06-06-2013 |
Hervé Letourneur, Mountain View, CA US
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20100312952 | Multiprocessor System Having an Input/Output (I/O) Bridge Circuit for Transferring Data Between Volatile and Non-Volatile Memory - A disclosed circuit includes circuitry for coupling to a volatile memory, circuitry for coupling to a nonvolatile NAND flash memory, and circuitry that: (i) receives a volatile memory request from a processor and satisfies the volatile memory request by accessing the volatile memory, and (ii) receives a nonvolatile NOR flash memory read request from the processor and satisfies the NOR read request by accessing both the NAND flash memory and the volatile memory. The circuit may also include circuitry that receives a volatile memory request from another processor and satisfies the volatile memory request from the other processor by accessing the volatile memory, and circuitry that receives a NAND flash memory read request from the other processor and satisfies the NAND read request by accessing the NAND flash memory. Multiprocessor systems including the circuit are described, as is a method for satisfying a NOR flash memory read request. | 12-09-2010 |
Hervé Jacques Clément Letourneur, San Francisco, CA US
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20140002428 | Dynamic Display Adjustment | 01-02-2014 |
Jean-Claude Letourneur, Pornichet FR
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20130237399 | CENTRIFUGE COMPRISING VISUAL AND/OR TACTILE INDICATOR FOR INDICATING THE ACCURATE MOUNTING OF THE ROTOR ON THE DRIVE SHAFT, AND CORRESPONDING ROTOR - A centrifuge is provided, which includes a drive shaft and a rotor intended to be removably mounted on the drive shaft in a mounting position. The drive shaft and the rotor are rotatably linked. The centrifuge also includes an axial locking device, which locks the rotor on the drive shaft and includes at least one male element supported by the rotor, resiliently biased and able to engage with a female element on the drive shaft. The male element(s) is(are) linked to a visual and/or tactile indicator, providing a visual and/or tactile indication of the engagement of the male element(s) with the female element. | 09-12-2013 |
20140329658 | Laboratory centrifuge comprising means for the locking in translation of a rotor on a driving motor shaft - A laboratory centrifuge includes two rotating parts ( | 11-06-2014 |
20140329659 | Laboratory centrifuge provided with means for the locking of a lid in its closed position - A laboratory centrifuge includes elements ( | 11-06-2014 |
20150038311 | CENTRIFUGE EQUIPPED WITH A BALANCING MECHANISM AND METHOD OF BALANCING SUCH A CENTRIFUGE - The disclosure relates to a centrifuge with a balancing mechanism and method of balancing such a centrifuge. The centrifuge includes a vertical shaft driven in rotation by a motor, and a mechanism for balancing the parts integral with said vertical shaft. The mechanism includes a plate integral with the vertical shaft, at least one compensating mass freely displacing on the plate, the mass being designed to limit the imbalance of parts integral with the vertical shaft, and a mechanism for blocking the compensating mass, the blocking mechanism being designed to immobilize the compensating mass on the plate when the rotation speed exceeds a determined value. | 02-05-2015 |
Mickael Letourneur, Vandelicourt FR
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20100059250 | FIXING DEVICE FOR WIRE CABLE TRAY - This device for wire cable trays including longitudinal warp wires and transverse weft wires has a base ( | 03-11-2010 |
Patrice Letourneur, Paris FR
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20090231178 | Downloadable remote control - A universal remote control ( | 09-17-2009 |
Patrick Letourneur, Coulsore FR
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20130002078 | ROTOR OF A MULTIPOLAR SYNCHRONOUS ELECTRIC MACHINE WITH SALIENT POLES - A rotor of a multipolar synchronous electric machine, with salient poles, includes a plurality of salient poles and a source of magnetomotive force, distributed on each of the salient poles, configured to generate a magnetic flux configured to encompass the armature of a stator, a part of the magnetic flux generated by the source of magnetomotive force, designated leakage flux, being dispersed between the salient poles of the rotor; the rotor including a magnetic compensation source configured to compensate the leakages of magnetic flux dispersed between the salient poles, the compensation source being dimensioned so as to compensate at least a part of the leakage flux. | 01-03-2013 |