Patent application number | Description | Published |
20090097489 | METHOD FOR TRACKING TRANSMISSION STATUS OF DATA TO ENTITIES SUCH AS PEERS IN A NETWORK - A method for tracking a transmission status of one or more data elements to one or more devices. In one example, the method includes providing a list including one or more devices and one or more data elements; processing the list to determine a data element of the one or more data elements to transmit to a device of one of the one or more devices; and upon successfully transmitting the data element to the device, adjusting the list so that the list indicates that the device has received the transmitted data element. In this manner, the status of whether a particular data element has been sent to a particular device can be easily derived from the list. | 04-16-2009 |
20110196985 | METHOD FOR TRACKING TRANSMISSION STATUS OF DATA TO ENTITIES SUCH AS PEERS IN A NETWORK - A method for tracking a transmission status of one or more data elements to one or more devices. In one example, the method includes providing a list including one or more devices and one or more data elements; processing the list to determine a data element of the one or more data elements to transmit to a device of one of the one or more devices; and upon successfully transmitting the data element to the device, adjusting the list so that the list indicates that the device has received the transmitted data element. In this manner, the status of whether a particular data element has been sent to a particular device can be easily derived from the list. | 08-11-2011 |
20120320921 | PACKET ROUTING AND SWITCHING DEVICE - A network device routes data packets by storing the packets in a switching memory as a function of a destination address of the packet. The switching memory comprises switching memory queues that are mapped to ports of the device. A header of a received packet is examined to determine the network destination address to which it is to be routed, and a destination queue is assigned to the packet based on the destination address. Thereafter, the packet is divided into cells, and the cells are written to contiguous locations in the destination queue. | 12-20-2012 |
Patent application number | Description | Published |
20100105135 | POROUS MEMBRANE DEVICE THAT PROMOTES THE DIFFERENTIATION OF MONOCYTES INTO DENDRITIC CELLS - Dendritic cells (DCs) for research and clinical applications are typically derived from purified blood monocytes that are cultured in a cocktail of cytokines for a week or more. Because it has been suggested that these cytokine-derived DCs may be deficient in some important immunological functions and might not accurately represent antigen-presenting cell (APC) populations found under physiologic conditions, there is a need for methods that allow the generation of DCs in a more physiologically relevant manner. The present invention comprises a simple and reliable technique for generating large numbers of highly purified DCs, based on a single migration of blood monocytes through endothelial cells that are cultured in, for example, a Transwell® device. The resultant APCs, harvested from the lower Transwell® chamber, resemble other in vitro-generated DC populations in their expression of major histocompatibility (MHC) and costimulatory molecules, ability to phagocytose foreign antigens, and capacity to trigger antigen-specific T cell responses. | 04-29-2010 |
20100184148 | IN VITRO GERMINAL CENTERS - The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days. | 07-22-2010 |
20110171689 | ARTIFICIAL IMMUNE SYSTEM: METHODS FOR MAKING AND USE - The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interaction with the immune system. | 07-14-2011 |
20110250620 | METHODS OF EVALUATING AN IMMUNE RESPONSE TO AN ANTIGEN - The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days. | 10-13-2011 |
20110269176 | METHODS FOR ASSAYING RESPONSES TO VACCINES - The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days. | 11-03-2011 |
20130078656 | ARTIFICIAL IMMUNE SYSTEM: METHODS OF USE - The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interaction with the immune system. | 03-28-2013 |
20140273209 | ARTIFICIAL IMMUNE SYSTEM: METHODS OF USE - The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interaction with the immune system. | 09-18-2014 |
Patent application number | Description | Published |
20100050129 | 3D Graphical User Interface For Simultaneous Management Of Applications - A method for providing a graphical user interface for an electronic device, wherein the electronic device having a display and a plurality of associated applications, comprising the steps: generating the appearance of a virtual three dimensional object having a plurality of panels, wherein the panels are positioned on the surface of the object; associating each of the panels to one of the applications; and displaying two or more of the panels of the object on the display, wherein the associated applications of the panels are displayed. | 02-25-2010 |
20110223973 | ONE-TOUCH DIAL - Apparatus having corresponding methods, and tangible computer-readable media embodying instructions executable by a computer to perform the methods, comprise: a touch panel; a character recognition module to recognize a character drawn on the touch panel; a contact module to select a contact, from a contact list containing a plurality of the contacts, based on the character recognized by the character recognition module, automatically when the character recognition module recognizes the character drawn on the touch panel. | 09-15-2011 |
20130165099 | Enhanced System and Method for Custom Programming of Large Groups of Phones Without Requiring Additional Equipment - A system and method for custom programming of mobile computing devices. The system and method include receiving, by a server computer and before activation of a mobile computing device by a user, a code from the mobile computing device over a wireless data connection; and in response to the receiving of the code, transmitting, by the server computer to the mobile computing device over the wireless data connection, a software module, the software module for execution on the mobile computing device and for installing software on the mobile computing device in response to the execution. | 06-27-2013 |
Patent application number | Description | Published |
20130190032 | Proxy-Based Push Service - A method and apparatus to proxy notification service connections between a mobile client and a notification server. In one embodiment of the invention, a proxy receives a proxy setup request for the notification service from the mobile client. The proxy further establishes a notification connection with the notification server for the mobile client and maintains the notification connection without waking an application processor of the mobile client. The proxy receives a notification from the notification service and forwards the notification to the mobile client. | 07-25-2013 |
20130242763 | METHOD TO USE NETWORK MEASUREMENTS TO OPTIMIZE MOBILE WIRELESS DEVICE PERFORMANCE - Method and apparatus for managing connections and state transitions between a mobile wireless device and a wireless network are described. The mobile wireless device measures network characteristics of radio sectors in the wireless network and saves the measured network characteristics in a database, later retrieving the network characteristics and determining data inactivity timeout values for the radio sector. The mobile wireless device manages connections and state transitions based on the determined data inactivity timeout values. The database of network characteristics is organized by geographic location. | 09-19-2013 |
20130303122 | Provisioning an Embedded Subscriber Identity Module - Provisioning an embedded subscriber identity module (eSIM) in a user equipment (UE) device with personalized subscriber information. A request may be transmitted for personalized subscriber information. The personalized subscriber information may be received. The personalized subscriber information may be installed in an eSIM in the UE device. | 11-14-2013 |
20140064095 | APPARATUS AND METHOD FOR OPTIMIZING COMMUNICATIONS AT AN INTERMITTENT COMMUNICATION LINK - Apparatus and methods for optimizing communications at a communication processor that exchanges communications across a communication link on behalf of an application processor or other local endstation of the communications, wherein the communication link is intermittently inoperative. The application processor is a source or destination of communication packets that traverse the link, while the communication processor transmits and receives the packets for the application processor. Packets are queued at the communication processor for transmit while the link is temporarily inoperative. A filter operates to select obsolete packets for discard. Obsolete packets may include packets for which a subsequent FIN packet (or other termination notice) is received, and may also include packets that have associated deadlines that expire or that will expire before they can be delivered. Obsolete packets may further include packets that have been retransmitted while the link is inoperative. | 03-06-2014 |
20140099925 | METHODS AND APPARATUS FOR DELIVERING ELECTRONIC IDENTIFICATION COMPONENTS OVER A WIRELESS NETWORK - Methods and apparatus enabling programming of electronic identification information of a wireless apparatus. In one embodiment, a previously purchased or deployed wireless apparatus is activated by a cellular network. The wireless apparatus connects to the cellular network using an access module to download operating system components and/or access control client components. The described methods and apparatus enable updates, additions and replacement of various components including Electronic Subscriber Identity Module (eSIM) data, OS components. One exemplary implementation of the invention utilizes a trusted key exchange between the device and the cellular network to maintain security. | 04-10-2014 |
20140143826 | POLICY-BASED TECHNIQUES FOR MANAGING ACCESS CONTROL - A policy-based framework is described. This policy-based framework may be used to specify the privileges for logical entities to perform operations associated with an access-control element (such as an electronic Subscriber Identity Module) located within a secure element in an electronic device. Note that different logical entities may have different privileges for different operations associated with the same or different access-control elements. Moreover, the policy-based framework may specify types of credentials that are used by the logical entities during authentication, so that different types of credentials may be used for different operations and/or by different logical entities. Furthermore, the policy-based framework may specify the security protocols and security levels that are used by the logical entities during authentication, so that different security protocols and security levels may be used for different operations and/or by different logical entities. | 05-22-2014 |
20140223074 | NON-VOLATILE MEMORY MONITORING - The invention provides a technique for managing write operations issued to a non-volatile memory included in a wireless device. A monitor software application executes on the wireless device and is configured to determine that a number of write operations issued to the non-volatile memory is greater than or equal to a write operation threshold associated with the non-volatile memory. In response, at least one application is isolated as the application responsible for issuing excessive write operations. The isolation can be carried out locally on the wireless device, or the isolation can be carried out remotely at a server by sending information about the write operations to the server. The monitor then limits additional write operations from being issued to the non-volatile memory so as to protect the non-volatile memory from becoming corrupted or inoperable. | 08-07-2014 |
20140349617 | PROVISIONING AN EMBEDDED SUBSCRIBER IDENTITY MODULE - Provisioning an embedded subscriber identity module (eSIM) in a user equipment (UE) device with personalized subscriber information. A request may be transmitted for personalized subscriber information. The personalized subscriber information may be received. The personalized subscriber information may be installed in an eSIM in the UE device. | 11-27-2014 |
20150017910 | APPARATUS AND METHODS FOR NEAR-FIELD COMMUNICATION BASED DEVICE CONFIGURATION AND MANAGMENT - Methods and apparatus for activating a mobile device for use with a service provider. In one embodiment, a powered-off mobile device having an inserted Subscriber Identity Module (SIM) may be programmed with configuration data while “in box” (e.g., at a point of sale (POS), in a warehouse, etc.) using a near field communication (NFC) data interface. In another exemplary embodiment, information that is stored to a NFC accessible memory can be accessed when the device is non-functional e.g., to retrieve backup data. | 01-15-2015 |
Patent application number | Description | Published |
20080279892 | Recombinant RSV Virus Expression Systems And Vaccines - The present invention relates to genetically engineered recombinant respiratory syncytial viruses and viral vectors which contain deletions of various viral accessory gene(s) either singly or in combination. In accordance with the present invention, the recombinant respiratory syncytial viral vectors and viruses are engineered to contain complete deletions of the M2-2, NS1, NS2, or SH viral accessory genes or various combinations thereof. In addition, the present invention relates to the attenuation of respiratory syncytial virus by mutagenisis of the M2-1 gene. | 11-13-2008 |
20090274727 | Recombinant RSV Virus Expression Systems And Vaccines - The present invention relates to genetically engineered recombinant respiratory syncytial viruses and viral vectors which contain deletions of various viral accessory gene(s) either singly or in combination. In accordance with the present invention, the recombinant respiratory syncytial viral vectors and viruses are engineered to contain complete deletions of the M2-2, NS1, NS2, or SH viral accessory genes or various combinations thereof. In addition, the present invention relates to the attenuation of respiratory syncytial virus by mutagenisis of the M2-1 gene. | 11-05-2009 |
20100028377 | Recombinant RSV Virus Expression Systems And Vaccines - The present invention relates to genetically engineered recombinant respiratory syncytial viruses and viral vectors which contain deletions of various viral accessory gene(s) either singly or in combination. In accordance with the present invention, the recombinant respiratory syncytial viral vectors and viruses are engineered to contain complete deletions of the M2-2, NS1, NS2, or SH viral accessory genes or various combinations thereof. In addition, the present invention relates to the attenuation of respiratory syncytial virus by mutagenisis of the M2-1 gene. | 02-04-2010 |
20110045023 | Recombinant RSV Virus Expression Systems And Vaccines - The present invention relates to genetically engineered recombinant respiratory syncytial viruses and viral vectors which contain deletions of various viral accessory gene(s) either singly or in combination. In accordance with the present invention, the recombinant respiratory syncytial viral vectors and viruses are engineered to contain complete deletions of the M2-2, NS1, NS2, or SH viral accessory genes or various combinations thereof. In addition, the present invention relates to the attenuation of respiratory syncytial virus by mutagenisis of the M2-1 gene. | 02-24-2011 |
20120308602 | Recombinant RSV Virus Expression Systems And Vaccines - The present invention relates to genetically engineered recombinant respiratory syncytial viruses and viral vectors which contain deletions of various viral accessory gene(s) either singly or in combination. In accordance with the present invention, the recombinant respiratory syncytial viral vectors and viruses are engineered to contain complete deletions of the M2-2, NS1, NS2, or SH viral accessory genes or various combinations thereof. In addition, the present invention relates to the attenuation of respiratory syncytial virus by mutagenisis of the M2-1 gene. | 12-06-2012 |
Patent application number | Description | Published |
20090221607 | Piperazine Derivatives - Compounds of general formula (I) | 09-03-2009 |
20100137334 | Piperidine and Piperazine Derivatives - Compounds of general formula (Ia): in which R | 06-03-2010 |
20110098241 | RAPAMYCIN ANALOGS AS ANTI-CANCER AGENTS - Analogs and derivatives of rapamycin are provided, wherein the analogs and derivatives can bind to FK-506 binding protein (FKBP), or inhibit the mTOR function of an FKBP, or both. The analogs and derivatives are rapamycin include the rapamycin skeleton substituted at the 42-hydroxyl group with certain specified chemically feasible groups. Methods of using the rapamycin analogs and derivatives in treatment of malconditions such as cancer, and methods of synthesizing the rapamycin analogs and derivatives, are provided. | 04-28-2011 |
20110124634 | BIOACTIVE COMPOUNDS FOR TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES - The invention provides bioactive compounds for the treatment of various malconditions such as cancer and neurodegenerative diseases including Alzheimer's disease. The chemical compounds as disclosed herein are found to show bioactivity in bioassays related to these conditions. Pharmaceutical compositions, combinations and methods of synthesis are provided, as are methods of using the compound, compositions and combinations in the treatment of the diseases. | 05-26-2011 |