Patent application number | Description | Published |
20080207666 | Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators - Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, Alzheimer's disease, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, Huntington's disease movement disorders, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders, the treatment of obesity or eating disorders, as well as the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, cirrhosis of the liver, non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and the promotion of wakefulness. | 08-28-2008 |
20080249093 | (3,4-Disubstituted)Propanoic Carboxylates as Sip (Edg) Receptor Agonists - The present invention encompasses compounds of Formula I: | 10-09-2008 |
20090042954 | 2-(Aryl)Azacyclylmethyl Carboxylates, Sulfonates, Phosphonates, Phosphinates and Heterocycles as S1p Receptor Antagonists - The present invention encompasses compounds of Formula I: | 02-12-2009 |
20090312307 | HETEROCYCLO INHIBITORS OF POTASSIUM CHANNEL FUNCTION - Novel heterocyclo compounds useful as inhibitors of potassium channel function (especially inhibitors of the K | 12-17-2009 |
20100029678 | DIURETICS - A compound having the structure | 02-04-2010 |
20120202845 | DIURETICS - A compound having the structure formula (I) or a pharmaceutically acceptable salt thereof, and methods of using the compounds for treating hypertension. | 08-09-2012 |
20120208838 | DIURETICS - A compound having the structure (I) wherein R is selected from the group consisting of 1) and 2), or a pharmaceutically acceptable salt thereof, and methods of using the compounds for treating hypertension. | 08-16-2012 |
20120232039 | PRIMARY AMINE DIAZENIUMDIOLATE HETEROCYCLIC DERIVATIVES - A compound having the structure | 09-13-2012 |
20130059823 | Diazeniumdiolate Cyclohexyl Derivatives - A compound having the structure (I) or a pharmaceutically acceptable salt thereof, wherein R | 03-07-2013 |
20130289003 | DIAZENIUMDIOLATE HETEROCYCLIC DERIVATIVES - A compound having the structure: useful for treating hypertension, Pulmonary Arterial Hypertension (PAH), congestive heart failure, conditions resulting from excessive water retention, cardiovascular disease, diabetes, oxidative stress, endothelial dysfunction, cirrhosis, pre-eclampsia, osteoporosis or nephropathy. | 10-31-2013 |
20140088048 | DIAZENIUMDIOLATE CYCLOHEXYL DERIVATIVES - A compound having the structure | 03-27-2014 |