Liotta, GA
Charles Liotta, Atlanta, GA US
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20130046092 | SWITCHABLE SOLVENTS AND METHODS OF USE THEREOF - A solvent that reversibly converts from a nonionic liquid mixture to an ionic liquid upon contact with a selected trigger, e.g., contact with CO | 02-21-2013 |
Charles L. Liotta, Atlanta, GA US
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20120116076 | SWITCHABLE SOLVENTS AND METHODS OF USE THEREOF - A solvent that reversibly converts from a nonionic liquid mixture to an ionic liquid upon contact with a selected trigger, e.g., contact with CO | 05-10-2012 |
20130096317 | REDUCTION OF ALDEHYDES AND KETONES TO ALCOHOLS - The embodiments described herein provide a reduction of an aldehyde or a ketone, such as a Meerwein-Ponnorf-Verley (MPV) reaction of an aldehyde or ketone. In some embodiments, the reaction occurs in the presence of Al[OC(CH | 04-18-2013 |
20130327989 | SWITCHABLE SOLVENTS AND METHODS OF USE THEREOF - A solvent that reversibly converts from a nonionic liquid mixture to an ionic liquid upon contact with a selected trigger, e.g., contact with CO | 12-12-2013 |
20140051888 | NOVEL STEREOISOMERIC MIXTURES, SYNTHESIS AND USES THEREOF - A novel stereochemical mixture of 1,6-diaryl-2,5-diaminohexanes, such as a mixture of stereoisomers of 1,6-diphenylhexane-2,5-diamine, is described. Also described are methods of preparing stereochemically pure 1,6-diaryl-2,5-diaminohexanes, and particularly stereochemically pure 1,6-diphenyl-2,5-diaminohexane. Also described is the use of both the mixture of stereoisomers and the individual stereoisomers. | 02-20-2014 |
Charles Leonard Liotta, Atlanta, GA US
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20100197892 | ORGANOSILICON-FUNCTIONAL PHASE TRANSFER CATALYSTS - Organosilicon-functional phase transfer catalysts (PTCs) and methods for transferring immiscible molecules into a silicon-functional phase employing an organosilicon-functional PTC are provided. | 08-05-2010 |
Dennis Liotta, Atlanta, GA US
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20090011991 | Novel Curcuminoid-Factor VIIA Constructs as Suppressors of Tumor Growth and Angiogenesis - The fluorinated curcuminoid (3,5-bis-(2-fluorobenzylidene)-piperidin-4-one-acetate is about ten times more effective at arresting the growth of tumor cells than cisplatin. Conjugates for delivering a cytotoxic compound, such as a curcuminoid, specifically to cancer cells and to the vascular endothelial cells that nourish solid tumors, and methods of making and using thereof are described herein. The conjugate contains a cytotoxic compound bound to a protein such as in factor VIIa that retains high affinity for the surface protein tissue factor. The cytotoxic compound is bound to the protein via a linker and a hydrolyzable bond. Upon complexation, the resulting heterodimer is endocytosed and the drug is subsequently liberated inside the target cell via proteolytic cleavage. | 01-08-2009 |
20100112561 | FLUORESCENT NUCLEOSIDE ANALOGUES - Briefly described, embodiments of the present disclosure include novel fluorescent nucleoside analogs (fNAs) including a fluorescent nucleobase, selected from a purine and a pyrimidine base or analog thereof, and a modified sugar moiety that differs in structure from a sugar moiety of a naturally occurring nucleoside. In embodiments, the fNAs of the present disclosure are analogues of NA prodrugs used to treat viral disorders. Embodiments of the present disclosure also include methods of making the novel fNAs of the present disclosure. | 05-06-2010 |
Dennis C. Liotta, Stone Mountain, GA US
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20090048190 | Antiviral activity and resolution of 2-hydroxymethyl-5(5-fluorocytosin-1-yl)-1,3-oxathiolane - A method and composition for the treatment of HIV and HBV infections in humans is disclosed that includes administering an effective amount of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane, a pharmaceutically acceptable derivative thereof, including a 5′ or N | 02-19-2009 |
20090239887 | Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers - A process for the resolution of a racemic mixture of nucleoside enantiomers that includes the step of exposing the racemic mixture to an enzyme that preferentially catalyzes a reaction in one of the enantiomers. The nucleoside enantiomer (−)-2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. | 09-24-2009 |
Dennis C. Liotta, Mcdonough, GA US
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20080234320 | CURCUMIN ANALOGS WITH ANTI-TUMOR AND ANTI-ANGIOGENIC PROPERTIES - The present invention is directed to curcumin analogs exhibiting anti-tumor and anti-angiogenic properties, pharmaceutical formulations including such compounds and methods of using such compounds. | 09-25-2008 |
20080293668 | [5-carboxamido or 5-fluoro]-[2',3'-unsaturated or 3'-modified]-pyrimidine nucleosides - A method and composition for the treatment of HIV and HBV infections in humans and other host animals is disclosed that includes the administration of an effective amount of a [5-carboxamido or 5-fluoro]-2′,3′-dideoxy-2′,3′-didehydro-pyrimidine nucleoside or a [5-carboxamido or 5-fluoro]-3′-modified-pyrimidine nucleoside, or a mixture or a pharmaceutically acceptable derivative thereof, including a 5′ or N | 11-27-2008 |
20080300398 | 2'-FLUORONUCLEOSIDES - A class of 2′-fluoro-nucleoside compounds are disclosed which are useful in the treatment of hepatitis B infection, hepatitis C infection, HIV and abnormal cellular proliferation, including tumors and cancer. The compounds have the general formulae: | 12-04-2008 |
20100173863 | 2-Fluoronucleosides - 2′-Fluoro-nucleoside compounds are disclosed which are useful in the treatment of hepatitis B infection, hepatitis C infection, HIV and abnormal cellular proliferation, including tumors and cancer. The compounds have the general formulae: | 07-08-2010 |
20130157971 | 2'-FLUORONUCLEOSIDES - 2′-Fluoro-nucleoside compounds are disclosed which are useful in the treatment of hepatitis B infection, hepatitis C infection, HIV and abnormal cellular proliferation, including tumors and cancer. The compounds have the general formulae: | 06-20-2013 |
Matthew Liotta, Atlanta, GA US
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20140352211 | Luminaire System, Method, and Apparatus for Optimizing Plant Growth in a Controlled Farming Environment Technological Field - A luminaire system, apparatus, and method of using thereof, is disclosed for optimizing plant growth in a controlled farming environment. Different types of plants have different light requirements, and different inputs to controlled farming environment have different costs. For example, there may be certain times of day where, if power is not used, a cost savings is realized. Thus, the present invention provides a luminaire system for these controlled farming environments that receives light requirement information for the different types of plants, and in turn, adjusts the luminaire light source (110) via a luminaire light interface (106) to based on the light requirement information. The light requirement information may include spectrum in formation for the type of spectrum required or needed by the plants, power cost or savings information, or light quantity information representing the maximum amount of light to be provided to the plants in the controlled environment. | 12-04-2014 |