Liu, DE
Andrew Hen Liu, Newark, DE US
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20080196168 | Washable leather with repellency - A washable leather having durable oil repellency, durable stain release, and durable water repellency is disclosed and a method of its preparation comprising contacting the leather during tanning with a composition which comprises at least one fluorinated urethane; at least one fluorinated ester; a mixture thereof; or a mixture of at least one fluorinated citrate urethane with at least one fluorinated urethane, at least one fluorinated ester, or a mixture of fluorinated urethane and fluorinated ester. | 08-21-2008 |
20110200829 | NON-AQUEOUS COMPOSITION COMPRISING PARTIALLY FLUORINATED METHACRYLIC POLYMERS - A solvent-based non-aqueous fluorinated methacrylate polymer comprising repeating units in any sequence from (1) at least one fluorinated methacrylate, and (2) at least one non-fluorinated alkyl acrylate and (3) at least one non-fluorinated hydroxyalkyl methacrylate, | 08-18-2011 |
Guangliang Liu, Wilmington, DE US
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20100237280 | ORE REDUCTION PROCESS USING CARBON BASED MATERIALS HAVING A LOW SULFUR CONTENT AND TITANIUM OXIDE AND IRON METALLIZATION PRODUCT THEREFROM - The disclosure is directed to a process for producing separable iron and titanium oxides from an ore comprising titanium oxide and iron oxide, comprising: (a) forming agglomerates comprising carbon-based material and the ore, the quantity of carbon of the agglomerates being at least sufficient for forming a ferrous oxide-containing molten slag, at an elevated temperature; (b) introducing the agglomerates onto a bed of carbon-based material in a moving hearth furnace, wherein the carbon-based materials used for both the agglomerates and the bed have a low sulfur content; (c) heating the agglomerates in the moving hearth furnace to a temperature sufficient for liquefying the agglomerates to produce a liquid comprising ferrous oxide-containing slag; (d) metallizing the ferrous oxide of the slag by reaction of the ferrous oxide and the carbon of the carbon bed at a furnace temperature sufficient for maintaining the slag in a liquid state; (e) solidifying the slag after metallization of the ferrous oxide to form a matrix of titanium oxide-rich slag having a plurality of metallic iron granules distributed there through; and (f) separating the metallic iron granules from the slag, the slag comprising greater than 85% titanium dioxide based on the entire weight of the matrix after separation of the metallic iron. The disclosure is also directed to a metallization product of a ferrous oxide-rich molten slag. | 09-23-2010 |
20110033608 | PROCESS FOR MAKING COATED, WATER-SWELLABLE HYDROGEL MICROSPHERES - A process for coating water-swellable hydrogel microspheres with various coating materials is described. The coating process described herein is a fluidized bed process, which utilizes inert, cofluidization particles to aid the fluidization of the microspheres. The use of the cofluidization particles increases the efficiency of the coating process and improves the quality of the coating obtained. | 02-10-2011 |
Guangliang Gary Liu, Wilmington, DE US
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20150147311 | HIGH FORCE AND HIGH STRESS DESTRUCTURING OF CELLULOSIC BIOMASS - A process for mechanical destructuring of cellulosic biomass was developed that makes use of a short application of high compression, impact, and shearing forces. The biomass may be destructured using a specific energy input that is less than 40% of the total combustible energy of the biomass. The destructured biomass, with or without saccharification and/or in-feed glycosyl hydrolase enzymes, may be used in feed applications. | 05-28-2015 |
Hansan Liu, Wilmington, DE US
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20130209897 | MESOPOROUS METAL OXIDE MICROSPHERE ELECTRODE COMPOSITIONS AND THEIR METHODS OF MAKING - Compositions and methods of making are provided for mesoporous metal oxide microspheres electrodes. The mesoporous metal oxide microsphere compositions comprise (a) microspheres with an average diameter between 200 nanometers (nm) and 10 micrometers (μm); (b) mesopores on the surface and interior of the microspheres, wherein the mesopores have an average diameter between 1 nm and 50 nm and the microspheres have a surface area between 50 m | 08-15-2013 |
Hemei Liu, Wilmington, DE US
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20150193377 | Sensitivity Analysis of an Independent Variable Based on Regression - According to one embodiment, a system includes one or more processors operable to determine an equation that provides a relationship between a dependent variable of the equation and a plurality of independent variables of the equation, and determine a predicted dependent variable based on the equation. The processors are further operable to, for one or more of the independent variables, perform a regression based on the predicted dependent variable. The processors are further operable to, for each of the one or more independent variables, determine a level of sensitivity and a level of relationship between the respective independent variable and the dependent variable. The processors are further operable to, for each of the one or more independent variables, communicate, for display an indication of the level of sensitivity and an indication of the level of relationship between the respective independent variable and the dependent variable. | 07-09-2015 |
Huaibing Liu, Dover, DE US
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20090030101 | Dental adhesive compositions and methods - Two-part and one-part self-etching dental adhesives containing polymerizable acidic monomers. Methods include one-coat application without need for tooth etching. | 01-29-2009 |
20090048364 | Self-adhesive dental cement - A dental, paste/paste self-adhesive cement includes a polymerizable acidic monomer or monomer mixtures; a polymerizable non-acidic monomer or monomer mixtures, a photo-initiator and/or a co-initiator, a reducing agent such as a benzoylthiourea and other substituted benzoylthiourea, an oxidizing agent, a thermal stabilizer and a glass filler. | 02-19-2009 |
20100298462 | Self-cure activator - A self curing activator for chemical polymerization of the interface of a dental bonding agent and a self curing or dual curing dental cement or restorative, includes an aryl borate compound, a polymerizable monomer, an optional acidic compound, an amine compound which exhibits a catalytic action, an organic peroxide containing material, and a metal compound wherein said metal compound promotes the decomposition of the organic peroxide. | 11-25-2010 |
20110112208 | Dental adhesive compositions and methods - Two-part and one-part self-etching dental adhesives containing polymerizable acidic monomers. Methods include one-coat application without need for tooth etching. | 05-12-2011 |
20120101183 | DENTAL ADHESIVE COMPOSITIONS AND METHODS - A one-part, self-etching dental adhesive is disclosed. The adhesive includes a hydrolytically stable acidic adhesive monomer and a hydrolytically stable, difunctional hydrophilic monomer. | 04-26-2012 |
20120172488 | One-component self-etching adhesive - A one-part, self-etching dental adhesive having improved performance such as adhesion performance with a simple one-coat application, without the need of separate acid-etching, a priming pre-treatment, or bonding step. The invention provides such improvements due to a function of the pH balance of the system in combination with an acid stable photoinitiating system. More specifically, the performance and pH balance is achieved through the employment of a hydrolytically stable, acidic, high-strength adhesive monomer (such as PENTA), with a stable, bifunctional, hydrophilic monomer (such as AHPMA) that yields greater crosslinking. | 07-05-2012 |
20130018123 | SELF-CURE ACTIVATORAANM Liu; HuaibingAACI DoverAAST DEAACO USAAGP Liu; Huaibing Dover DE USAANM Hammesfahr; Paul D.AACI WyomingAAST DEAACO USAAGP Hammesfahr; Paul D. Wyoming DE USAANM Pomrink; GregoryAACI DoverAAST DEAACO USAAGP Pomrink; Gregory Dover DE US - A self curing activator for chemical polymerization of the interface of a dental bonding agent and a self curing or dual curing dental cement or restorative, includes an aryl borate compound, a polymerizable monomer, an optional acidic compound, an amine compound which exhibits a catalytic action, an organic peroxide containing material, and a metal compound wherein said metal compound promotes the decomposition of the organic peroxide. | 01-17-2013 |
20130225716 | Acid-neutralizing Resins and Hardenable Dental Compositions Thereof - Disclosed herein are acid-neutralizing polymerizable and/or non-polymerizable resins, methods of making such resins, and dental compositions having such resins. | 08-29-2013 |
20150297465 | DENTAL ADHESIVE WITH POLYMERIZABLE BASIC MONOMERS - Disclosed herein is a basic dental composition comprising an adhesive composition, wherein the dental composition is suitable for use in dentistry. | 10-22-2015 |
Jun J Liu, Wilmington, DE US
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20140248529 | LITHIUM ION BATTERY - A lithium ion battery that has a spinel cathode and a nonaqueous electrolyte comprising a fluorinated acyclic carboxylic acid ester and/or a fluorinated acyclic carbonate solvent is described. The lithium ion battery operates at a high voltage (i.e. up to about 5 V) and has improved cycling performance at high temperature. | 09-04-2014 |
20140272555 | CATHODE MATERIAL AND BATTERY - A lithium ion battery cathode material, and an electrode prepared from such material, is described. The cathode material has a layered-spinel composite structure. The lithium ion battery operates at a high voltage (i.e. up to about 5 V) and has a desirably high cycling performance and rate capability. | 09-18-2014 |
Minye Liu, Wilmington, DE US
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20140323786 | CONTINUOUS MIXING REACTOR AND METHOD OF USE - A continuous mixing reactor has an outer shell having a cylindrical portion with a central section and two opposite conical end sections; a circulation tube within the shell so that an annular passage forms between the shell and the circulation tube; an impeller within and positioned adjacent to one end of the circulation tube; and heat exchange means penetrating the outer shell and extending into the end of the circulation tube opposite the impeller. The outer shell has a hydraulic head forming one end of the shell, a heat exchange medium header at the opposite end of the shell. The circulation tube nearer the heat exchange medium header terminates at or downstream from a tangential plane extending through the shell at the intersection of the central section and the conical end section of the cylindrical portion of shell. The reactor is useful in an alkylation process. | 10-30-2014 |
Minye Liu, Hockessin, DE US
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20110147305 | LIQUID-LIQUID EXTRACTION TOWER HAVING CENTER FEED INLET AND PROCESS - This invention relates to a liquid-liquid extraction tower comprising a feed inlet and a plurality of stages and an area for collection of the extract; at least one stage comprising a mixing zone having a driven center horizontal impeller positioned between a pair of horizontal annular shroud baffles having open centers, the impeller having a center impeller plate; wherein the feed inlet is positioned adjacent the center impeller plate. This invention also relates to an improved liquid-liquid extraction process comprising symmetrically introducing the feed adjacent the center impeller plate. | 06-23-2011 |
Phillip C.c. Liu, Wilmington, DE US
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20120263676 | COMPOSITIONS, METHODS AND KITS RELATING TO HER-2 CLEAVAGE - The present invention relates to compositions, methods and kits based on the ADAM-mediated cleavage of Her-2. The present invention also relates to treatments for cancer, and in particular, breast cancer, by modulating the ADAM-mediated cleavage of Her-2. Further, the invention relates to compositions, methods and kits based on the surprising synergistic effect between inhibition of Her-2 cleavage by an ADAM and certain cytostatic (e.g., Herceptin) and cytotoxic (e.g., Taxol) compounds in, among other things, inhibiting tumor cell proliferation and inducing cell death. Additionally, the invention relates to novel variants of ADAM15, designated ADAM15 variant 1 and ADAM15 variant 2, now identified and isolated. | 10-18-2012 |
Pingli Liu, Newark, DE US
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20090291956 | SALTS OF 2-FLUORO-N-METHYL-4-[7-(QUINOLIN-6-YL-METHYL)-IMIDAZO[1,2-b][1,2,- 4]TRIAZIN-2-YL]BENZAMIDE AND PROCESSES RELATED TO PREPARING THE SAME - The present invention is directed to dihydrochloric acid and dibenzenesulfonic acid salts of the c-Met kinase inhibitor 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and pharmaceutical compositions thereof, useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. The present invention further relates to processes and intermediates for preparing 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and salts thereof. | 11-26-2009 |
20100015178 | 1,2,5-OXADIAZOLES AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 01-21-2010 |
20120058079 | 1,2,5-Oxadiazoles as Inhibitors of Indoleamine 2,3-Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 03-08-2012 |
20120077798 | AZETIDINE AND CYCLOBUTANE DERIVATIVES AS JAK INHIBITORS - The present invention relates to azetidine and cyclobutane derivatives, as well as their compositions, methods of use, and processes for preparation, which are JAK inhibitors useful in the treatment of JAK-associated diseases including, for example, inflammatory and autoimmune disorders, as well as cancer. | 03-29-2012 |
20130060026 | PROCESSES AND INTERMEDIATES FOR MAKING A JAK INHIBITOR - This invention relates to processes and intermediates for making {1-{1-[3-fluoro-2-(trifluoromethyl)isonicotinoyl]piperidin-4-yl}-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile, useful in the treatment of diseases related to the activity of Janus kinases (JAK) including inflammatory disorders, autoimmune disorders, cancer, and other diseases. | 03-07-2013 |
20130225556 | AZETIDINE AND CYCLOBUTANE DERIVATIVES AS JAK INHIBITORS - The present invention relates to azetidine and cyclobutane derivatives, as well as their compositions, methods of use, and processes for preparation, which are JAK inhibitors useful in the treatment of JAK-associated diseases including, for example, inflammatory and autoimmune disorders, as well as cancer. | 08-29-2013 |
20130289036 | SALTS OF 2-FLUORO-N-METHYL-4-[7-(QUINOLIN-6-YL-METHYL)-IMIDAZO[1,2-B][1,2,- 4]TRIAZIN-2-YL]BENZAMIDE AND PROCESSES RELATED TO PREPARING THE SAME - The present invention is directed to dihydrochloric acid and dibenzenesulfonic acid salts of the c-Met kinase inhibitor 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and pharmaceutical compositions thereof, useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. The present invention further relates to processes and intermediates for preparing 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and salts thereof. | 10-31-2013 |
20140023663 | 1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3-Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 01-23-2014 |
20140256941 | PROCESSES AND INTERMEDIATES FOR MAKING A JAK INHIBITOR - This invention relates to processes and intermediates for making {1-{1-[3-fluoro-2-(trifluoromethyl)isonicotinoyl]piperidin-4-yl}-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile, useful in the treatment of diseases related to the activity of Janus kinases (JAK) including inflammatory disorders, autoimmune disorders, cancer, and other diseases. | 09-11-2014 |
20140315962 | 1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3- Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 10-23-2014 |
20150148348 | SALTS OF 2-FLUORO-N-METHYL-4-[7-(QUINOLIN-6-YL-METHYL)- IMIDAZO[1,2-B][1,2,4]TRIAZIN-2-YL]BENZAMIDE AND PROCESSES RELATED TO PREPARING THE SAME - The present invention is directed to dihydrochloric acid and dibenzenesulfonic acid salts of the c-Met kinase inhibitor 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and pharmaceutical compositions thereof, useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. The present invention further relates to processes and intermediates for preparing 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and salts thereof. | 05-28-2015 |
20150183805 | PROCESSES AND INTERMEDIATES FOR MAKING A JAK INHIBITOR - This invention relates to processes and intermediates for making {1-{1-[3-fluoro-2-(trifluoromethyl)isonicotinoyl]piperidin-4-yl}-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile, useful in the treatment of diseases related to the activity of Janus kinases (JAK) including inflammatory disorders, autoimmune disorders, cancer, and other diseases. | 07-02-2015 |
20150190378 | 1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3- Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 07-09-2015 |
20150344497 | PROCESSES OF PREPARING A JAK1 INHIBITOR AND NEW FORMS THERETO - This invention relates to processes for preparing a JAK1 inhibitor having Formula Ia: | 12-03-2015 |
Wen Liu, Newark, DE US
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20090050269 | Method For Reducing Degradation in A Fuel Cell - The invention is a method of reducing catalyst dissolution in the cathode of a membrane electrode assembly fuel cell, the method comprising the steps of: (a) preparing a membrane electrode assembly comprising an anode, a cathode and a polymer electrolyte membrane interposed between the anode and the cathode; (b) assembling a fuel cell using the membrane electrode assembly; (c) applying a fluid comprising an oxidant to the cathode of the membrane electrode assembly; (d) applying a fluid comprising a fuel to the anode of the membrane electrode assembly; and (e) supplying a sufficient quantity of reducing agent to the cathode to maintain the average open-circuit voltage of the cathode at less than about 0.98 V. | 02-26-2009 |
20130203874 | Expandable Functional TFE Copolymer Fine Powder, Expanded Products and Reacted Products Therefrom - A functional TFE copolymer fine powder is described, wherein the TFE copolymer is a polymer of TFE and at least one functional comonomer, and wherein the TFE copolymer has functional groups that are pendant to the polymer chain. The functional TFE copolymer fine powder resin is paste extrudable and expandable. Methods for making the functional TFE copolymer are also described. The expanded functional TFE copolymer material may be post-reacted after expansion. | 08-08-2013 |
Wen K. Liu, Newark, DE US
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20110039960 | Expandable Functional TFE Copolymer Fine Powder, the Expanded Functional Products Obtained Therefrom and Reaction of the Expanded Products - A functional TFE copolymer fine powder is described, wherein the TFE copolymer is a polymer of TFE and at least one functional comonomer, and wherein the TFE copolymer has functional groups that are pendant to the polymer chain. The functional TFE copolymer fine powder resin is paste extrudable and expandable. Methods for making the functional TFE copolymer are also described. The expanded functional TFE copolymer material may be post-reacted after expansion. | 02-17-2011 |
20120035283 | Expandable Functional TFE Copolymer Fine Powder, the Expanded Functional Products Obtained Therefrom and Reaction of the Expanded Products - A functional TFE copolymer fine powder is described, wherein the TFE copolymer is a polymer of TFE and at least one functional comonomer, and wherein the TFE copolymer has functional groups that are pendant to the polymer chain. The functional TFE copolymer fine powder resin is paste extrudable and expandable. Methods for making the functional TFE copolymer are also described. The expanded functional TFE copolymer material may be post-reacted after expansion. | 02-09-2012 |
20130084460 | Expandable Functional TFE Copolymer Fine Powder, Expanded Products and Reacted Products Therefrom - A functional TFE copolymer fine powder is described, wherein the TFE copolymer is a polymer of TFE and at least one functional comonomer, and wherein the TFE copolymer has functional groups that are pendant to the polymer chain. The functional TFE copolymer fine powder resin is paste extrudable and expandable. Methods for making the functional TFE copolymer are also described. The expanded functional TFE copolymer material may be post-reacted after expansion. | 04-04-2013 |
20140005286 | Expandable Functional TFE Copolymer Fine Powder, Expanded Products and Reacted Products Therefrom | 01-02-2014 |
Xuesong Liu, Hockessin, DE US
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20160000795 | TREATMENT OF B-CELL MALIGNANCIES BY A COMBINATION JAK AND PI3K INHIBITORS - This invention relates to methods of treating B-cell malignancies using a combination of inhibitors of JAK1 and/or JAK2 and inhibitors of PI3Kδ. | 01-07-2016 |