Macbeath
Calum Macbeath, Francavilla Al Mare IT
Patent application number | Description | Published |
---|---|---|
20120010122 | Polymeric Compositions For Sustained Release Of Volatile Materials - A polymeric composition comprising a copolymer of ethylene with at least another monomer comprising at least a heteroatom, a tackifier, less than 10% of a compatible plasticizer or blend of plasticizers and a volatile material. The compositions are able to deliver effectively the volatile material incorporated for a long time and also have good adhesion properties on most substrates. | 01-12-2012 |
Calum Macbeath, Singapore SG
Patent application number | Description | Published |
---|---|---|
20150141319 | POLYMERIC COMPOSITIONS FOR SUSTAINED RELEASE OF VOLATILE MATERIALS - A polymeric composition comprising a copolymer of ethylene with at least another monomer comprising at least a heteroatom, a tackifier, less than 10% of a compatible plasticizer or blend of plasticizers and a volatile material. The compositions are able to deliver effectively the volatile material incorporated for a long time and also have good adhesion properties on most substrates. | 05-21-2015 |
Gavin Macbeath, Wakefield, MA US
Patent application number | Description | Published |
---|---|---|
20140242070 | FRIZZLED 2 AS A TARGET FOR THERAPEUTIC ANTIBODIES IN THE TREATMENT OF CANCER - Disclosed herein are methods of treating cancer in a subject, and methods for inhibiting growth, migration and/or invasion of a cancer cell in the subject, comprising administering to the subject a therapeutically effective amount of an antibody or antigen binding fragment thereof that downmodulates Fzd2. The antibody may specifically bind Fzd2, and may promote internalization of the Fzd2 receptor by the cancer cells and/or prevent ligand binding to Fzd2. Specific antibodies, and also specific portions of the Fzd2 molecule for antibody binding are disclosed. In one embodiment the antibody specifically binds to the epitope HGAEQICVGQNHSEDGAPAL (SEQ ID NO: 1). Specific cancers (e.g. late stage hepatocellular carcinoma), intended for treatment are provided, and include cancers that exhibit overexpression of Fzd2, and/or Wnt5a. | 08-28-2014 |
20140248280 | ANTI-ERBB3 ANTIBODIES IN COMBINATION WITH PACLITAXEL FOR TREATMENT OF GYNECOLOGICAL CANCERS - Provided are methods and compositions for clinical treatment of advanced gynecological cancers using anti-ErbB3 antibodies combined with paclitaxel. | 09-04-2014 |
20150231238 | OVERCOMING RESISTANCE TO ERBB PATHWAY INHIBITORS - Provided are methods for overcoming resistance to an ErbB pathway inhibitor, such as an EGFR inhibitor or a HER2 inhibitor. The resistance may be acquired resistance to an EGFR inhibitor, such as acquired resistance to gefitinib. In the methods provided, a subject exhibiting resistance to an ErbB pathway inhibitor is selected and both an ErbB 3 inhibitor and a second ErbB pathway inhibitor are administered to the subject, such as an EGFR inhibitor or a HER2 inhibitor. Also provided are methods for inhibiting the growth of a tumor comprising a T790M EGFR mutation by contacting the tumor with an ErbB3 inhibitor and an EGFR inhibitor. Compositions for overcoming resistance to an ErbB pathway inhibitor, comprising both an ErbB 3 inhibitor and a second ErbB pathway inhibitor, such as an EGFR inhibitor or a HER2 inhibitor, are also provided. | 08-20-2015 |
Gavin Macbeath, Boston, MA US
Patent application number | Description | Published |
---|---|---|
20150246335 | METHODS FOR MULTIPLEX ANALYTICAL MEASUREMENTS IN SINGLE CELLS OF SOLID TISSUES - The invention provides a method for the isolation of a single cell embedded in a tissue while preserving the state of molecules of the cell, and therefore allows for transformation of a single target cell in live tissue into a format that can be evaluated using analytical methods. | 09-03-2015 |
Keith Stewart Rattray Macbeath, Fort Lee, NJ US
Patent application number | Description | Published |
---|---|---|
20140214496 | DYNAMIC PROFITABILITY MANAGEMENT FOR CLOUD SERVICE PROVIDERS - An example method for dynamic profitability management for cloud service providers can include utilizing a processing resource to execute instructions stored on a medium to recommend adjustment of prices for a number of cloud services provided by a cloud service provider to manage profitability based upon analyzing input of input profiles. The input profiles can include a market price profile per workload unit, a behavioral profile per customer, a scheduled workload profile per offered cloud service, and a workload capacity profile per cloud service placement option. | 07-31-2014 |