Madin
Andrew Madin, Cambridge GB
Patent application number | Description | Published |
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20090186919 | PIPERIDINE DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE - Compounds of formula (I) modulate the activity of gamma secretase and hence find use in treatment or prevention of Alzheimer's disease and related conditions. | 07-23-2009 |
20090239905 | PIPERIDINES AND RELATED COMPOUNDS FOR THE TREATMENT OF DEMENTIA - Compounds of formula I: modulate the action of gamma secretase, and hence find use in treatment of Alzheimer's disease and related conditions. | 09-24-2009 |
20100048623 | PIPERIDINES AND RELATED COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE - Compounds of formula (I) are modulators of gamma-secretase, and hence are useful in treatment of Alzheimer's disease. | 02-25-2010 |
20100093718 | Compounds - The invention relates to new bicyclic heterocyclic derivative compounds of Formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer The compounds of Formula (I) are inhibitors of FGFR, VEGFR or PDGFR. | 04-15-2010 |
20100120761 | Bicyclic Heterocyclic Compounds as FGFR Inhibitors - The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer. | 05-13-2010 |
20120208791 | IMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES - The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer. | 08-16-2012 |
Andrew Madin, Hatfield GB
Patent application number | Description | Published |
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20120202828 | FUSED AMINODIHYDROPYRIMIDONE DERIVATIVES - A compound represented by the general formula (I) or a pharmaceutically acceptable salt thereof or a solvate thereof, wherein Ring A is a C | 08-09-2012 |
Andrew Madin, Hatfield Hertfordshire GB
Kairat Madin, Penzberg DE
Patent application number | Description | Published |
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20110306094 | METHOD FOR OBTAINING IMMUNOGLOBULIN ENCODING NUCLEIC ACID - The current invention is directed to a method for obtaining a nucleic acid encoding an immunoglobulin variable domain from a single cell comprising the following steps:—performing a first polymerase chain reaction with three to six 5′-primer and one 3′-primer, performing with the product of the first polymerase chain reaction a second polymerase chain reaction with thirteen to sixteen 5′-primer and one 3′-primer, whereby the distance of the binding locations of the primer employed in the second polymerase chain reaction is reduced compared to the first polymerase chain reaction. | 12-15-2011 |
20150024434 | METHOD FOR OBTAINING FAB FRAGMENTS FROM SINGLE ANTIBODY PRODUCING CELLS BY MULTIPLEXED CPR IN COMBINATION WITH TaqMan PROBES - Herein is reported a method for a multiplex one tube real-time reverse-transcriptase gene-specific polymerase chain reaction for the amplification and quantification of cognate IgG heavy and light chains encoding nucleic acids (human IgG isotype) from a single cell. | 01-22-2015 |
Mark Michael Madin, Canton, MI US
Patent application number | Description | Published |
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20130220289 | INTAKE SYSTEM WITH AN INTEGRATED CHARGE AIR COOLER - An intake assembly in an engine is provided. The intake assembly includes a compressor and a plenum in fluidic communication with the compressor, the plenum having an integrated charge air cooler including a coolant inlet and a coolant outlet in fluidic communication with a coolant passage and cooling plates extending into a plenum enclosure and coupled to the coolant passage. The intake assembly further includes a throttle body coupled to the plenum. | 08-29-2013 |