Martial
Martial Balland, Saint Martin D'Heres FR
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20140236313 | MICROSTRUCTURED ADHESION SUBSTRATE FOR ANIMAL OR HUMAN CELLS - The present invention relates to an adhesion substrate for at least one animal or human cell on the surface of which is generated an adhesion pattern for at least one animal or human cell, said pattern including at least two areas adhering to said cell, which are spaced apart by an area not adhering to said cell on which a polymer not adhering to said cell is immobilized, characterized in that the polymer is selected so as to have a conformation which may be modified by varying a parameter of the environment in which the substrate is found, to a method for preparing such a substrate and to the cell analysis methods using such a substrate. | 08-21-2014 |
Martial Blochet, Saint Germain En Laye FR
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20140288942 | Pill Dispensing System for Monitoring Compliant Receipt of Pills by a Patient - A pill dispensing system for monitoring compliant receipt of pills by a patient, comprising a base unit having an area adapted to receive a pill container, the base unit comprising a microprocessor and a power supply, the pill container comprising a plurality of breakable closures each sealing a respective one of the pill compartments, each breakable closure comprising a breakable conductor being adapted to break upon breaking of the breakable closure of a respective one of the pill compartments and to generate a first pill compartment opening signal on the microprocessor, said base unit further comprising a plurality of optical detectors, each optical detector being associated with a respective one of the pill compartments of the pill container and being adapted to generate a second pill compartment opening signal on the microprocessor upon the breaking of the breakable closure of a respective one of the pill compartments. | 09-25-2014 |
Martial Broucke, Trie Chateau FR
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20160083109 | METAL FASTENER - The invention relates to a metal fastener that makes it possible to ensure an electrically conductive surface along the entire thickness of structural elements to be assembled. The fastener thereby comprises a head and a smooth shank extending along an axis of revolution, characterized in that the shank comprises at least one conductive portion and one lubricating portion disposed along the axis of revolution of the fastener along at least one length of the shank. The inventive fastener makes it possible to ensure a conductive surface in the entire thickness of the structure in which it is installed. | 03-24-2016 |
Martial Cozic, Breux Sur Avre FR
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20100243751 | Thermal energy management device for a vehicle - The invention relates to a thermal energy management device for a vehicle, namely a vehicle equipped with an electric generator associating and fuel cell and hydrogen reformer, comprising at least one primary circuit circulating a first heat-conducting fluid, such circuit enabling calories to be collected from a thermal source and transported to at least one thermal exchanger wherein said device comprises at least one thermal exchanger constituted by a sorption exchanger, enabling the thermal energy management of vehicles, and namely, armored vehicles. | 09-30-2010 |
Martial Desgeorges, Marcoussis FR
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20110165365 | METHOD AND DEVICE FOR ENCAPSULATING MICROSTRUCTURES - A method for encapsulating structures ( | 07-07-2011 |
Martial Grousseaud, Castres FR
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20090137826 | Method for preparing 4beta-amino-4'-demethyl-4-desoxypodophyllotoxin - The invention relates to a method for synthesizing 4β-amino-4′-demethyl-4-desoxypodophyllotoxin of formula (1), characterized by comprising the following successive steps: a) reacting, in a pure weak acid or in a mixture consisting of acid, water and of organic solvent, without another solvent, at a temperature higher than the ambient temperature, thiourea with 4β-halogenoacetamido-4′-demethyl-4-desoxypodophyllotoxin, and; b) recovering the 4β-amino-4′-demethyl-4-desoxypodophyllotoxin. | 05-28-2009 |
20100280263 | Process for the Synthesis of Anticancer (Poly) Aminoalkylaminoacetamide Derivatives of Epipodophyllotoxin - The present invention describes a new process for the preparation of (poly)aminoalkylaminoacetamide compounds of epipodophyllotoxin useful for their applications in therapeutics as anticancer agents. This process comprises a step of condensation of a primary-amine-containing reactant, whose amine functions are not protected, with β-chloroacetamido-4′-epipodophyllotoxin in a polar aprotic organic solvent. | 11-04-2010 |
20110021791 | Method for preparing 4B-amino-4'-demethyl-4-desoxypodophyllotoxin - The invention relates to a method for synthesizing 4β-amino-4′-demethyl-4-desoxypodophyllotoxin of formula (1), characterized by comprising the following successive steps: a) reacting, in a pure weak acid or in a mixture consisting of acid, water and of organic solvent, without another solvent, at a temperature higher than the ambient temperature, thiourea with 4β-halogenoacetamido-4′-demethyl-4-desoxypodophyllotoxin, and; b) recovering the 4β-amino-4′-demethyl-4-desoxypodophyllotoxin. | 01-27-2011 |
20120022273 | PROCESS FOR THE PREPARATION OF (POLY) AMINOALKYLAMINOACETAMIDE DERIVATIVES OF EPIPODOPHYLLOTOXIN USEFUL FOR THEIR APPLICATIONS IN THERAPEUTICS AS ANTICANCER AGENT - The present invention relates to a new process for the preparation of (poly)aminoalkylaminoacetamide derivatives of epipodophyllotoxin and salts thereof, characterised in that it comprises a step of peptide coupling of 4-amino-4′-demethylepipodophyllotoxin with an amine-containing reactant having protecting groups. | 01-26-2012 |
Martial Kijewski, Guyancourt FR
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20110170583 | METHOD FOR TRACKING THE PHASE OF A SIGNAL MODULATED BY CONTINUOUS PHASE MODULATION AND SYNCHRONIZATION DEVICE IMPLEMENTING SAID METHOD - A method for tracking the phase of a signal modulated by a continuous phase modulation includes: a complex vector representative of the received signal is determined for each symbol period with an offset of a half symbol period relative to the symbol rate of the receiver; a level measurement is performed on two complex samples distributed with an offset roughly of a half symbol period either side of the instant of estimation of the complex vector; the complex vectors are associated with one of the points of the constellation of the modulation making it possible to find the point which is closest; average estimation of the offset of the phase is calculated by calculating the difference between the average estimation of the phase of the signal and the theoretical phase value associated with each point of the constellation; an absolute estimation and a differential estimation of the offset of the phase is calculated. | 07-14-2011 |
Martial Luepold, Hubersdorf CH
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20150059186 | HAND-HELD POWER TOOL INFORMATION DEVICE - A hand-held power tool information device includes at least one detection unit configured to detect at least one processing distance covered by a cutting edge of a processing tool on a workpiece. The detection unit is also configured to detect the at least one processing distance independently of a guide rail. The hand-held power tool information device can further include a distance sensor unit that is configured to detect at least one distance value. | 03-05-2015 |
Martial Monseu, Velizy-Villacoublay FR
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20150314859 | AIRCRAFT UNDERCARRIAGE LEG INCLUDING A UNIT FOR DRIVING THE WHEELS - Aircraft undercarriage leg including an axle ( | 11-05-2015 |
Martial Ruat, Orsay FR
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20110275663 | N-Acylthiourea and N-Acylurea Inhibitors of the Hedgehog Protein Signalling Pathway - The present invention relates to the use of acylthiourea or acylurea derivatives for the treatment of pathologies involving a tissue dysfunction associated with a deregulation of the Hedgehog protein signalling pathway, and also to novel acylthiourea or acylurea derivatives as such, to their use as a medicinal product, and to pharmaceutical compositions containing them. | 11-10-2011 |
20120196865 | Acyl Guanidine Derivatives Modulating The Hedgehog Protein Signaling Pathway - The present invention relates to acyl guanidine derivatives modulating the hedgehog protein signaling pathway to be used as drugs, in particular for treating diseases involving a tissue dysfunction associated with a deregulation of the hedgehog protein signaling pathway, as well as to pharmaceutical compositions containing same. The present invention also relates to novel acyl guanidine derivatives as such. | 08-02-2012 |
20130236912 | Use Of Quinolinone Derivatives As A Research Tool - The present invention relates to the use of quinolinone derivatives of general formula (I), ligands of the Smo receptor or of related receptors which target a binding site of the receptor which is different from the known ligand binding sites, as research tools for identifying modulators of the Smo receptor or of related receptors, characterizing the Hedgehog signalling pathway and diagnosis; the invention also relates to kits containing said derivatives of general formula (I). | 09-12-2013 |
20130267559 | Quinolinone Derivatives - The present invention relates to compounds which are quinolinone derivatives of general formula (I) capable of modulating the activity, in particular of inducing the differentiation, of stem and progenitor cells; these compounds are of use in the treatment of disorders related to a stem differentiation defect; the invention also relates to novel compounds among these quinolinone derivatives and to pharmaceutical compositions containing the same. | 10-10-2013 |
Martial Taillefert, Atlanta, GA US
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20100120125 | BACTERIAL BIOMINERALIZATION OF CONTAMINANTS - The various embodiments of the present disclosure relate generally to bacterial biomineralization of contaminants and, more particularly, to methods, systems and compositions for the biomineralization of soil and water contaminants, such as metals and radionuclides. In one aspect of the present invention, a method for the in situ biomineralization of a soil contaminant comprises: providing a plurality of bacteria to a soil comprising at least one contaminant, wherein at least one bacterium expresses a phosphatase; providing a phosphate-rich material to the soil; reacting at least one bacterium expressing a phosphatase with the phosphate-rich material in the presence of the contaminant; and immobilizing the contaminant in the soil. | 05-13-2010 |
Martial Vicq, Colmar FR
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20130008062 | WEAR ASSEMBLY FOR AN EXCAVATOR BUCKET - A wear assembly for an excavator bucket comprises a cast lip, a lower wing shroud and a retaining member. The cast lip includes two upstanding wing plates. Each wing plate has a wing face on a side of the wing plate and a plate retaining formation formed on the wing face. The plate retaining formation has a plate retaining face. The wing shroud is mounted to the wing plate. The wing shroud includes a shroud retaining formation having a shroud retaining face. The retaining member includes a first bearing formation having a first face opposing and engaging the shroud retaining face, and a second bearing formation having a second face opposing and engaging the plate retaining face. The retaining member has a longitudinal axis extending between the first bearing formation and the second bearing formation. The longitudinal axis is located in a plane substantially parallel to the wing face. | 01-10-2013 |
20140082976 | WING SHROUD FOR AN EARTH MOVING MACHINE BUCKET, BUCKET AND EARTH MOVING MACHINE - The present disclosure refers to a wing shroud for an earth moving machine bucket adapted to be positioned at least partially on a tooth adapter and/or at least partially on a lateral plate of the bucket for protecting wear sensitive bucket parts wherein the wing shroud comprises at least one self-lock mechanism for a detachable connection to the bucket. | 03-27-2014 |
20140237869 | EXCAVATOR BUCKET AND EARTH MOVING MACHINE - The present disclosure relates to an excavator bucket for an earth moving machine comprising an interior bucket space formed by a curved rear wall and a pair of opposed sidewalls wherein the bucket comprises a bucket box arranged onto the rear wall, in particular arranged on the outer surface of its top portion, and which extends along a lateral axis of the bucket wherein the angle between at least one of the outer lateral sides of the bucket box and the rear wall of the bucket, in particular its top portion, is less than 90 degrees. | 08-28-2014 |