Mary E.
Mary E. Abood, Gladwyne, PA US
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20120122987 | TREATMENT OF DISORDERS ASSOCIATED WITH G PROTEIN-COUPLED RECEPTOR 35 (GPR35) - Compounds are provided having agonistic activity against G protein-coupled receptor 35 (GPR35). The compounds are useful for providing antinociception, providing neuroprotection in case of stroke or ischemia, or treating gastric inflammation. | 05-17-2012 |
20150265561 | TREATMENT OF DISORDERS ASSOCIATED WITH G PROTEIN-COUPLED RECEPTOR 35 (GPR35) - Compounds are provided having agonistic activity against G protein-coupled receptor 35 (GPR35). The compounds are useful for providing antinociception, providing neuroprotection in case of stroke or ischemia, or treating gastric inflammation. | 09-24-2015 |
Mary E. Allocco, Woodbury, TN US
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20130062811 | PLASTIC PUMP HOUSING AND MANUFACTURE THEREOF - A method of making a pump housing that is net-molded and immediately assumes its final shape and design specification without requiring more than de minimis secondary machining processes. The method utilizes molds and cores configured such that none of the fluid ports of the housing produced using the molds and cores have any intersecting geometry. | 03-14-2013 |
20140021650 | Plastic Pump Housing and Manufacture Thereof - A method of making a pump housing that is net-molded and immediately assumes its final shape and design specification without requiring more than de minimis secondary machining processes. The method utilizes molds and cores configured such that none of the fluid ports of the housing produced using the molds and cores have any intersecting geometry. The net-molded pump housing may also include a cross-tube insert providing flow communication between a fluid inlet port and a pressure relief port. | 01-23-2014 |
20150132429 | PLASTIC PUMP HOUSING AND MANUFACTURE THEREOF - A method of making a pump housing that is net-molded and immediately assumes its final shape and design specification without requiring more than de minimis secondary machining processes. The method utilizes molds and cores configured such that none of the fluid ports of the housing produced using the molds and cores have any intersecting geometry. | 05-14-2015 |
Mary E. Alwin, Crawfordsville, IN US
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20080264525 | HIGH COPPER LOW ALLOY STEEL SHEET - A high copper low alloy steel sheet less than 5 mm is made by preparing a molten melt producing an as-cast low alloy steel comprising by weight, 0.02 % to 0.3% carbon, 0.10% to 1.5% manganese, 0.01% to 0.5% silicon, greater than 0.01 % and less than or equal 0.15% phosphorus, less than 0.05% aluminum, more than 0.20% copper, less than 0.03 % tin, less than 0.10 % nickel, total oxygen level at least 70 ppm and usually less than 250 ppm, free oxygen content 20 to 70 ppm, the remainder iron and impurities, solidifying the melt into sheet less than 10 mm thickness in a non-oxidizing atmosphere to below 1080° C. Copper content may be between 0.2% and 2.0% by weight. The steel may have a corrosion index (I) of at least 6.0 in accordance with ASTM G101 where: I=26.01 (% Cu)+3.88 (% Ni)+1.20 (% Cr)+1.49 (% Si)+17.28 (% P)−7.29 (% Cu)(% Ni)−9.10 (% Ni)(% P)−33.39 (% Cu) | 10-30-2008 |
Mary E. Alwin-Becker, Crawfordsville, IN US
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20100215981 | HOT ROLLED THIN CAST STRIP PRODUCT AND METHOD FOR MAKING THE SAME - A hot rolled steel strip made by the steps including assembling a twin roll caster, forming a casting pool of molten steel having a free oxygen content between 20 and 75 ppm and having a composition such that the cast strip comprises by weight, less than 0.25% carbon, between 0.9 and 2.0% manganese, between 0.05 and 0.50% silicon, greater than 0.01% and less than or equal to 0.15% phosphorus, and less than 0.01% aluminum, counter rotating the casting rolls forming the steel strip, hot rolling the strip such that mechanical properties at 10% and 35% reduction are within 10% for yield strength, tensile strength and total elongation, and coiling the strip at a temperature between 300 and 700° C. to provide a majority of the microstructure comprising bainite and acicular ferrite. Alternatively, the steel may have between 0.20 and 0.60% copper and manganese as low as 0.08%. | 08-26-2010 |
20130302644 | HOT ROLLED THIN CAST STRIP PRODUCT AND METHOD FOR MAKING THE SAME - A hot rolled steel strip made by the steps including assembling a twin roll caster, forming a casting pool of molten steel having a free oxygen content between 20 and 75 ppm and having a composition such that the cast strip comprises by weight, greater than 0.1 and not more than 0.5% carbon, between 0.9 and 2.0% manganese, between 0.05 and 0.50% silicon, greater than 0.01% and less than or equal to 0.15% phosphorus, and less than 0.01% aluminum, counter rotating the casting rolls forming the steel strip, hot rolling the strip such that mechanical properties at 10% and 35% reduction are within 10% for yield strength, tensile strength and total elongation, and coiling the strip at a temperature between 300 and 700° C. to provide a majority of the microstructure comprising bainite and acicular ferrite. Alternatively, the steel may have between 0.20 and 0.60% copper and manganese as low as 0.08%. | 11-14-2013 |
Mary E. Bellizzi, North Chicago, IL US
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20100317568 | Anti-Viral Compounds - Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection. | 12-16-2010 |
20110092415 | Anti-Viral Compounds - Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection. | 04-21-2011 |
20110207699 | Anti-Viral Compounds - Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection. | 08-25-2011 |
20140315792 | ANTI-VIRAL COMPOUNDS - Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection. | 10-23-2014 |
Mary E. Bellizzi, Lake Forest, IL US
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20120004196 | Anti-Viral Compounds - Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection. | 01-05-2012 |
Mary E. Birli, Garfield Heights, OH US
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20100155545 | MODULAR ROOFTOP PIPE SUPPORT - An extruded or molded elastomeric (e.g., rubber) or polymeric multi-piece (e.g., two-piece) modular pipe support system utilizes a wide base with protrusions and/or recesses, and a separate top with recesses and/or protrusions that engage the protrusions and/or recesses of the top. The tops are configured to securely capture a pipe/conduit without any additional parts, straps, etc. The top may have one or more pipe-receiving recesses for receiving the pipes (conduits). | 06-24-2010 |
Mary E. Brunkow, Seattle, WA US
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20080234219 | Compositions and Methods for Increasing Bone Mineralization - A novel class or family of TGF-β binding proteins is disclosed. Also disclosed are assays for selecting molecules for increasing bone mineralization and methods for utilizing such molecules. | 09-25-2008 |
20090169543 | Method for regulating immune function in primates using the Foxp3 protein - Isolated nucleic acid molecules are provided which encode Fkh | 07-02-2009 |
20100003755 | Methods for identifying genomic deletions - The genomic locus responsible for Van Buchem's disease is narrowed to an approximately 92 kb region of human chromosome 17 at 17q21. Individuals afflicted with or carriers of Van Buchem's disease exhibit a 52 kb deletion within this 92 kb region. Methods are provided that permit the differentiation between individuals homozygous for and therefore afflicted with Van Buchem's disease, individuals heterozygous for and therefore carriers of Van Buchem's disease, and individuals who are normal with respect to Van Buchem's disease. Also provided are general methodologies for the detection of a wide variety of large genomic deletions. | 01-07-2010 |
20110070588 | Methods for Identifying Genomic Deletions - The genomic locus responsible for Van Buchem's disease is narrowed to an approximately 92 kb region of human chromosome 17 at 17q21. Individuals afflicted with or carriers of Van Buchem's disease exhibit a 52 kb deletion within this 92 kb region. Methods are provided that permit the differentiation between individuals homozygous for and therefore afflicted with Van Buchem's disease, individuals heterozygous for and therefore carriers of Van Buchem's disease, and individuals who are normal with respect to Van Buchem's disease. Also provided are general methodologies for the detection of a wide variety of large genomic deletions. | 03-24-2011 |
20110150866 | Compositions and Methods for Increasing Bone Mineralization - A novel class or family of TGF-β binding proteins is disclosed. Also disclosed are assays for selecting molecules for increasing bone mineralization and methods for utilizing such molecules. | 06-23-2011 |
20120129170 | Methods for Identifying Genomic Deletions - The genomic locus responsible for Van Buchem's disease is narrowed to an approximately 92 kb region of human chromosome 17 at 17q21. Individuals afflicted with or carriers of Van Buchem's disease exhibit a 52 kb deletion within this 92 kb region. Methods are provided that permit the differentiation between individuals homozygous for and therefore afflicted with Van Buchem's disease, individuals heterozygous for and therefore carriers of Van Buchem's disease, and individuals who are normal with respect to Van Buchem's disease. Also provided are general methodologies for the detection of a wide variety of large genomic deletions. | 05-24-2012 |
20130121995 | Compositions and Methods for Increasing Bone Mineralization - A novel class or family of TGF-β binding proteins is disclosed. Also disclosed are assays for selecting molecules for increasing bone mineralization and methods for utilizing such molecules. | 05-16-2013 |
Mary E. Caryk, Batavia, NY US
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20090239451 | Automatic Shift Dual-Action Tool - Tools providing automatic, smooth shifting between random orbital and rotary motion by simply increasing or decreasing force applied are taught. Exemplar is a finishing tool switchable between grinding rotary action and random orbital sanding action without powering down and without any mechanical manipulation, made possible by having a clutch mechanism affixed directly to the spindle assembly, which also eliminates the need to dissemble the tool in order to change a backup pad, saving time and money. Direct relationship between the clutch and spindle eliminates need for a specialty pad allowing for use of a variety of backup pads, reducing the cost of replacement backup pads and increasing the functionality of the dual-function tool. An additional feature is that the drive head surface is circular and large enough to encompass the device's circular clutch plate, which means that the available friction surface area of the clutch plate is efficiently utilized. | 09-24-2009 |
Mary E. Couwenhoven, Fairport, NY US
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20080279440 | METHOD FOR RENDERING DIGITAL RADIOGRAPHIC IMAGES FOR DISPLAY BASED ON INDEPENDENT CONTROL OF FUNDAMENTAL IMAGE QUALITY PARAMETERS - A system for enhancing a digital image. The system includes: means for providing a digital image; means for decomposing the provided digital image into a multi-frequency band representation of four frequency bands as follows: a lowest frequency band image which represents large-sized features in the digital image; a low-to-mid frequency band image which represents mid-sized features of the digital image; a mid-to-high frequency band image which represents the small-sized features in the digital image; and a highest frequency band which represents very fine detail in the digital image; means for manipulating said low-to-mid frequency band image to produce a contrast effect without affecting the overall dynamic range of said digital image; means for multiplying each of said high-frequency band images with a gain factor; means for summing together said unmodified low frequency band image and said modified high-frequency band images to produce a reconstructed digital image; and means for mapping said reconstructed digital image through a tone-scale look-up table to map said reconstructed digital image to optical densities. | 11-13-2008 |
20100086182 | DIAGNOSTIC IMAGE PROCESSING WITH AUTOMATIC SELF IMAGE QUALITY VALIDATION - A method for medical diagnostic image processing obtains digital image data for a diagnostic image and extracts one or more image features from the image data, obtaining one or more image properties from the one or more extracted features. An image quality aim is obtained for rendered image appearance according to one or more stored viewer preferences. Rendering parameters are generated according to the obtained image quality aim and the one or more obtained image properties. The image is rendered according to the generated rendering parameters and the rendering validated against the selected image quality aim. | 04-08-2010 |
20140376798 | RIB ENHANCEMENT IN RADIOGRAPHIC IMAGES - A method for radiographic imaging obtains a radiographic image of a patient's chest and processes the obtained image to generate a default radiographic image and a bone-enhanced image. At least a portion of one or more ribs within the default radiographic image is detected and a rib mask generated according to the at least the detected portion of the one or more ribs. The rib mask is applied to the bone-enhanced image to define masked enhanced image content that includes the detected at least the portion of one or more ribs. A composite image that combines the masked enhanced image content with the default radiographic image is generated and displayed. | 12-25-2014 |
20150279059 | METHOD FOR ENHANCED DISPLAY OF IMAGE SLICES FROM 3-D VOLUME IMAGE - A method for rendering volume radiographic image content of a subject forms a volume image. The method extracts a first image slice from the volume image, then modifies the extracted first image slice by defining two or more spatial frequency bands from the image slice data and applying one or more viewer adjustments to the image slice data, wherein the one or more viewer adjustments condition the image data to enhance image content in at least one of the defined spatial frequency bands. A set of display rendering parameters is generated according to the two or more frequency bands and according to viewer adjustments made for the first image slice. A second image slice is extracted from the volume image. The generated set of display rendering parameters is applied to the second image slice to render an adjusted image slice and the adjusted image slice is displayed. | 10-01-2015 |
Mary E. Ewasyshyn, Thornhill CA
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20080311624 | Chimeric immunogens - Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV. | 12-18-2008 |
20080312412 | Chimeric immunogens - Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV. | 12-18-2008 |
Mary E. Koban, Chadds Ford, PA US
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20090120619 | METHOD FOR EXCHANGING HEAT IN VAPOR COMPRESSION HEAT TRANSFER SYSTEMS - The present disclosure relates to a method for exchanging heat in a vapor compression heat transfer system. In particular, it relates to use of an intermediate heat exchanger to improve performance of a vapor compression heat transfer system utilizing a working fluid comprising at least one fluoroolefin. In addition, the present disclosure relates to a vapor compression heat transfer system comprising an intermediate heat exchanger in combination with a dual-row evaporator or a dual-row condenser, or both. | 05-14-2009 |
20110290447 | METHOD FOR EXCHANGING HEAT IN VAPOR COMPRESSION HEAT TRANSFER SYSTEMS - A multi-step method is disclosed for exchanging heat in a vapor compression heat transfer system having a working fluid circulating therethrough. The method includes the step of circulating a working fluid comprising a fluoroolefin to an inlet of a first tube of an internal heat exchanger, through the internal heat exchanger and to an outlet thereof. Also disclosed are vapor compression heat transfer systems for exchanging heat. The systems include an evaporator, a compressor, a dual-row condenser and an intermediate heat exchanger having a first tube and a second tube. A disclosed system involves a dual-row condenser connected to the first and second intermediate heat exchanger tubes. Another disclosed system involves a dual-row evaporator connected to the first and second intermediate heat exchanger tubes. | 12-01-2011 |
20130284464 | METHODS OF REDUCING FLAME PROPOGATION IN SYSTEMS WITH A FLAMMABLE REFRIGERANT - The present invention provides methods for reducing the propagation of a flame to or from a refrigerant source and an ignition source in or adjacent to a cooling system, comprising positioning a metal mesh flame arrestor between said refrigerant source and said ignition source. The methods allow the use of flammable refrigerants with reduced risk of fire. | 10-31-2013 |
20150108176 | CAN TAP - Disclosed are can taps for dispensing fluids from containers. The can tap has a housing with a housing net and a housing outlet, and a pin and a tap outlet. The pin has a flow portion in fluid communication with the housing inlet and housing outlet. The flow portion of the pin may be a hollow shaft. The pin has a blunt depressor capable of operating a valve on the container. The can tap may have a gasket comprising a material having a hardness that prevents deformation of the container. | 04-23-2015 |
20150203278 | CAN TAP - Disclosed are can taps for dispensing fluids from containers. The can tap has a housing with an inlet and an outlet, and a pin. The pin has a flow portion in fluidic communication with the inlet and the outlet of the housing. The pin may have a blunt depressor capable of operating a valve on the container. The flow portion of the pin allows fluid to flow between the housing and the pin. The can tap may have a gasket comprising a material having a hardness that prevents deformation of the container. | 07-23-2015 |
Mary E. Kubiszak, Indianapolis, IN US
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20130288897 | SYNERGISTIC PESTICIDAL COMPOSITIONS - Synergistic pesticidal compositions including a pesticide/herbicide mixture are provided. | 10-31-2013 |
Mary E. Kundus, Hudson, WI US
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20130166318 | SYSTEM AND TECHNIQUES FOR COST ESTIMATION OF MEDICAL CONDITIONS ACQUIRED AT A MEDICAL FACILITY - Computer-implemented methods of processing medical data are described. The methods comprise selecting cases associated with a first parameter from medical data associated with a plurality of cases, determining a subset of cases associated with a medical facility-acquired condition, and determining another subset cases not associated with the medical facility-acquired condition. Estimated costs associated with those cases associated a medical facility-acquired condition are generated, along with expected costs for these same cases in the absence of the medical facility-acquired condition. Methods further allowing comparisons to data related to normative collections of medical facilities are also disclosed. Computerized systems for processing medical data and computer-readable storage media comprising instructions that when executed in a processor cause the processor to process medical data are also described. | 06-27-2013 |
20130290018 | HEALTH CARE DELIVERY VERIFICATION METHODS, APPARATUS, AND SYSTEMS - Methods, apparatus and systems for verifying proper delivery of health care bundles to patients are described. The methods, apparatus, and systems may be configured to monitor the delivery of health care bundles to one or more patients, to collect delivery data such as sounds and/or images that can be processed to determine if delivery of the health care bundle is being or has been properly delivered to a patient, to provide feedback during delivery of a health care bundle to a patient, and/or to store an indicator that is indicative of proper delivery of the health care bundle. | 10-31-2013 |
Mary E. Lidstrom, Seattle, WA US
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20130196359 | SYSTEMS AND METHODS FOR BIOTRANSFORMATION OF CARBON DIOXIDE INTO HIGHER CARBON COMPOUNDS - Systems, compounds and methods for the conversion of C1 carbon compounds to higher carbon compounds useful for the generation of commodity compounds. | 08-01-2013 |
Mary E. Mizialko, Naperville, IL US
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20100142956 | Method and Apparatus for Reshaping a Channel Signal - Higher rate channels (e.g., 40 Giga bits or greater) have large bandwidths and are susceptible to inter-channel crosstalk. Optical tunable filters may be used to overcome crosstalk. Tunable filters do not maintain their central wavelength over a long duration or a wide temperature range. An example embodiment of the present invention relates to shaping a channel signal within a dense wavelength division multiplexing signal and may employ a tunable filter and input and output optical power detectors to measure a modulated source channel signal at an input of the tunable filter and a filtered modulated source channel signal at an output of the tunable filter. A controller is configured to adjust a center wavelength of the tunable filter as a function of a difference between measurements of optical power by the optical power detectors. Adjusting the center wavelength shapes the channel signal and overcomes undesired effects for higher rate channels. | 06-10-2010 |
Mary E. Moore, Barrington, NH US
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20080236943 | SOUND PROOFING SYSTEM AND METHOD - A low-cost and easy to manufacture static structure and method for soundproofing walls, floors, and/or ceilings of rooms in new and/or existing construction utilizes an asphalt based flexible membrane as one or more sound absorbing layers which may be applied to an existing wall panel or first applied to one or more unmounted wall panels to form a laminated structure which is then affixed to the walls, floor or ceiling to be soundproofed. The wall panel is preferably gypsum wallboard. Each sound absorbing layer, in addition to soundproofing, may also serve to prevent or at least reduce air or water infiltration to and from the room. | 10-02-2008 |
20090288360 | SOUND PROOFING SYSTEM AND METHOD - A low-cost and easy to manufacture static structure and method for soundproofing walls, floors, and/or ceilings of rooms in new and/or existing construction utilizes an asphalt based flexible membrane as one or more sound absorbing layers which may be applied to an existing wall panel or first applied to one or more unmounted wall panels to form a laminated structure which is then affixed to the walls, floor or ceiling to be soundproofed. The wall panel is preferably gypsum wallboard. Each sound absorbing layer, in addition to soundproofing, may also serve to prevent or at least reduce air or water infiltration to and from the room. | 11-26-2009 |
Mary E. Mootoo, Cincinnati, OH US
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20110251612 | ELECTROSURGICAL CUTTING AND SEALING INSTRUMENTS WITH CAM-ACTUATED JAWS - Various embodiments are directed to a surgical instrument comprising, a shaft, and an end effector. The shaft may be coupled to the handle and may extend distally along a longitudinal axis. The end effector may be positioned at a distal end of the shaft and may comprise first and second jaw members and a reciprocating member. The first and second jaw members may define first and second longitudinal slots. One or both of the jaw members may be pivotable relative to the other about a pivot point. The reciprocating member may be translatable distally and proximally parallel to the longitudinal axis and through the first and second longitudinal slots. A distal portion of the reciprocating member may define a blade. The instrument may comprise an overtube translatable distally to exert a force on a portions of the first and second jaw members tending to close the first and second jaw members. | 10-13-2011 |
20110306963 | ELECTROSURGICAL INSTRUMENT EMPLOYING AN ELECTRODE - An electrosurgical surgical instrument can comprise a handle and an end effector, wherein the end effector can comprise first and second jaws which can be opened and closed in order to capture tissue therebetween. In various embodiments, the first and second jaws can comprise one or more electrodes configured to apply a voltage across the tissue, wherein at least one of the electrodes can comprise a conductive material positioned within a non-conductive, or high-resistance, material. In use, current flowing through the conductive material can heat the conductive material and cause it to evaporate and leave behind the non-conductive material. In such circumstances, the current flowing through the electrode may cease or may be substantially reduced. | 12-15-2011 |
20110306965 | ELECTROSURGICAL INSTRUMENT EMPLOYING MULTIPLE POSITIVE TEMPERATURE COEFFICIENT ELECTRODES - An electrosurgical surgical instrument can comprise a handle and an end effector, wherein the end effector can comprise first and second jaws which can be opened and closed in order to capture tissue therebetween. In various embodiments, the first and second jaws can comprise one or more electrodes configured to apply a voltage across the tissue, wherein one or both of the first and second jaws can include a plurality of electrodes each comprised of a positive temperature coefficient material having a different switching temperature. The electrical resistances of the electrodes can increase significantly once the temperature of the electrodes exceed their switching temperatures and, owing to the increased electrical resistance, the flow of current through the electrodes can be reduced and/or prevented. In various circumstances, the different switching temperatures of the electrodes can allow some of the electrodes to switch off before the other electrodes. | 12-15-2011 |
20110306966 | ELECTROSURGICAL INSTRUMENT EMPLOYING A PLURALITY OF ELECTRODES - An electrosurgical surgical instrument can comprise a handle and an end effector, wherein the end effector can comprise first and second jaws which can be opened and closed to capture tissue therebetween. The second jaw can comprise a first electrode and a second electrode while the first jaw can comprise an opposing electrode positioned opposite the first electrode and the second electrode when the jaws are in their closed position. The first and second electrodes can be independently and/or sequentially operated in order to conduct current between the first and second electrodes and opposing electrode in order to draw the tissue positioned between the first and second jaws toward the center of the first and second jaws and weld the tissue. In various other embodiments, other firing sequences of the electrodes are contemplated. During and/or after such tissue welding processes, a cutting member can be advanced to cut the tissue. | 12-15-2011 |
20110306968 | HEAT MANAGEMENT CONFIGURATIONS FOR CONTROLLING HEAT DISSIPATION FROM ELECTROSURGICAL INSTRUMENTS - In various embodiments, a surgical instrument is provided that may comprise an end effector for performing a surgical procedure on tissue, for example. The end effector may comprise at least one energy delivery surface and heat dissipation means for dissipating heat from at least a portion of the end effector. For example, in at least one embodiment, the end effector may comprise a first jaw, a second jaw, and a cutting member. The cutting member may comprise a cutting surface and a body, which may define a cavity and at least one opening communicating with the cavity. A fluid may be moved through the cavity to and/or from the opening(s). Additionally, in at least one embodiment, a surgical instrument's end effector may comprise a first jaw, a second jaw, a cutting member, and at least one heat pipe. Various other heat dissipation means are also disclosed. | 12-15-2011 |
20120010616 | SURGICAL INSTRUMENT COMPRISING AN ARTICULATABLE END EFFECTOR - An electrosurgical instrument can comprise a handle, a shaft, and an end effector, wherein the end effector can be rotatably coupled to the shaft by an articulation joint. The instrument can further comprise a drive member and the articulation joint can comprise flexible support members which can be configured to support the drive member. The instrument can further comprise supply wires electrically coupled to electrodes in the end effector and a wire tensioning device configured to prevent the supply wires from accumulating slack within the articulation joint. The drive member can comprise a plurality of flexible layers wherein some of the layers can be comprised of an electrically insulative material and other layers can be comprised of an electrically conductive material which is in electrical communication with a cutting member in the end effector and/or electrodes positioned within the end effector. | 01-12-2012 |
20120012638 | SURGICAL INSTRUMENTS WITH ELECTRODES - An end-effector assembly configured to be attached to a surgical instrument. The end-effector assembly comprises a first jaw and a second jaw comprising a staple cavity. At least one of the first jaw and the second jaw is movable relative to the other jaw. The end-effector assembly comprises a staple removably positioned within the staple cavity and an electrically-conductive driver configured to move the staple between a first stored position in which the staple is at least partially positioned within the staple cavity and a second position in which the staple is at least partially deployed from the staple cavity into tissue positioned intermediate the first jaw and the second jaw. The staple comprises an electrode. | 01-19-2012 |
20120022525 | ELECTROSURGICAL INSTRUMENT WITH SEPARATE CLOSURE AND CUTTING MEMBERS - In various embodiments, a surgical instrument is provided that may comprise an end effector for performing a surgical procedure on tissue, for example. The end effector may comprise a pair of jaws, a closure beam, and a cutting member. The closure beam and the cutting member may be releasably coupled together by an interlocking member such that movement of the cutting member may cause the closure beam to also move relative to the jaws and cause the jaws to close and grip tissue, for example. The interlocking member may then unlock, allowing the cutting member to move through the gripped tissue and relative to the closure beam. Additionally, the cutting member and closure beam may be operated by a single trigger, which may be configured to provide haptic feedback to a user at various stages. Further, the jaws may be electrically energized to deliver energy and/or seal the gripped tissue. | 01-26-2012 |
20120022526 | ELECTROSURGICAL CUTTING AND SEALING INSTRUMENT - A surgical instrument for supplying energy to tissue can comprise a jaw member comprising an electrode, wherein the electrode is configured to supply energy from a power source to captured tissue. The surgical instrument comprises a tissue-cutting element to transect the captured tissue. The rate of distal translation of the tissue-cutting element during the operational stroke is regulated by at least one biasing member, such as a spring, for example. | 01-26-2012 |
20120101488 | SURGICAL INSTRUMENT WITH MAGNETIC CLAMPING FORCE - A surgical instrument comprising an end effector, the end effector comprising first and second opposing jaw members, wherein at least one of the first and second jaw members are moveable such that the first and second jaw members are transitionable between open and closed positions. The first jaw member may comprise a permanent magnet. The second jaw member may also comprise a magnet (e.g., permanent or soft). The magnetic motive force between the magnets of the first and second jaw members may attract each other to thereby reduce the external force required to transition the first and second jaw members to the closed position. In addition, the magnets may be configured to repeal each other to thereby aid in opening the jaw members. | 04-26-2012 |
20140194874 | ELECTROSURGICAL END EFFECTOR WITH INDEPENDENT CLOSURE FEATURE AND BLADE - An apparatus includes a body, an end effector, and outer beam, and an inner beam. The body comprises an actuator. The end effector is in communication with the body and has a first jaw and a second jaw. The outer beam is able to advance within the end effector such that the outer beam closes the second jaw toward the first jaw. The advancement of the outer beam is controlled mainly by the actuator. The inner beam is also able to advance within the end effector such that the inner beam transects tissue. The actuator is operable to control the advancement of the inner beam in at least two stages. The actuator advances the inner beam and the outer beam together in a first state. The actuator advances the inner beam while the outer beam remains stationary in a second stage. | 07-10-2014 |
20140276732 | ELECTROSURGICAL INSTRUMENT WITH RESTRICTED TRIGGER - An apparatus for operating on tissue includes an end effector, a first actuator, and a second actuator. The end effector includes a first jaw pivotable relative to a second jaw to a closed position. The first actuator is movable from a first position to a second position to pivot the first jaw to the closed position. The first actuator engages the second actuator in the second position to selectively provide RF energy to the end effector. | 09-18-2014 |
20140330271 | ELECTROSURGICAL INSTRUMENT WITH SEPARATE CLOSURE AND CUTTING MEMBERS - In various embodiments, a surgical instrument is provided that may comprise an end effector for performing a surgical procedure on tissue, for example. The end effector may comprise a pair of jaws, a closure beam, and a cutting member. The closure beam and the cutting member may be releasably coupled together by an interlocking member such that movement of the cutting member may cause the closure beam to also move relative to the jaws and cause the jaws to close and grip tissue, for example. The interlocking member may then unlock, allowing the cutting member to move through the gripped tissue and relative to the closure beam. Additionally, the cutting member and closure beam may be operated by a single trigger, which may be configured to provide haptic feedback to a user at various stages. Further, the jaws may be electrically energized to deliver energy and/or seal the gripped tissue. | 11-06-2014 |
20140343550 | ELECTROSURGICAL CUTTING AND SEALING INSTRUMENTS WITH CAM-ACTUATED JAWS - Various embodiments are directed to a surgical instrument comprising, a shaft, and an end effector. The shaft may be coupled to the handle and may extend distally along a longitudinal axis. The end effector may be positioned at a distal end of the shaft and may comprise first and second jaw members and a reciprocating member. The first and second jaw members may define first and second longitudinal slots. One or both of the jaw members may be pivotable relative to the other about a pivot point. The reciprocating member may be translatable distally and proximally parallel to the longitudinal axis and through the first and second longitudinal slots. A distal portion of the reciprocating member may define a blade. The instrument may comprise an overtube translatable distally to exert a force on a portions of the first and second jaw members tending to close the first and second jaw members. | 11-20-2014 |
20150196352 | HEAT MANAGEMENT CONFIGURATIONS FOR CONTROLLING HEAT DISSIPATION FROM ELECTROSURGICAL INSTRUMENTS - In various embodiments, a surgical instrument is provided that may comprise an end effector for performing a surgical procedure on tissue, for example. The end effector may comprise at least one energy delivery surface and heat dissipation means for dissipating heat from at least a portion of the end effector. For example, in at least one embodiment, the end effector may comprise a first jaw, a second jaw, and a cutting member. The cutting member may comprise a cutting surface and a body, which may define a cavity and at least one opening communicating with the cavity. A fluid may be moved through the cavity to and/or from the opening(s). Additionally, in at least one embodiment, a surgical instrument's end effector may comprise a first jaw, a second jaw, a cutting member, and at least one heat pipe. Various other heat dissipation means are also disclosed. | 07-16-2015 |
Mary E. Rabaglia, Lodi, WI US
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20110071222 | POTENTIATORS OF INSULIN SECRETION - The present invention relates to a recognition that an analog of αKG can increase glucose-induced insulin secretion in vitro and in vivo in animals, particularly in mammals, and more particularly in humans and in rodents. By employing the methods of the invention, insulin secretion can be increased. | 03-24-2011 |
Mary E. Robischon, Minneapolis, MN US
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20160038733 | MECHANICAL FEEDTHROUGHS FOR IMPLANTABLE MEDICAL DEVICE - An implantable medical device assembly comprises a sealed housing; a motor including a rotating output shaft within the sealed housing; a first coaxial shaft within the sealed housing, the first coaxial shaft being mechanically coupled to the rotating output shaft such that rotation of the rotating output shaft drives rotation of the first coaxial shaft; a second coaxial shaft external to the sealed housing, the second coaxial shaft being in axial alignment with the first coaxial shaft; an oscillating component mechanically coupling the first coaxial shaft to the second coaxial shaft, wherein rotation of the rotating first coaxial shaft drives the oscillation of the oscillating component, wherein the oscillation of the oscillating component drives rotation of the second coaxial shaft; and a flexible seal including the oscillating component. The sealed housing and the flexible seal combine to form a substantially sealed enclosure encasing the motor and the first coaxial shaft. | 02-11-2016 |
Mary E. Roth, West Palm Beach, FL US
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20130112355 | MAGNETIC CURTAIN - The present invention describes a window covering which is useful for securing to objects having windows without using permanent attachment devices. The window covering preferably contains a plurality of magnets arranged along the upper end and along the lower end. The magnets are arranged so that they are coupleable or securable to a metal part of a window itself or a metal surface which houses the window as well as one or more additional magnets positioned within the window covering. | 05-09-2013 |
20140251560 | MAGNETIC CURTAIN ADAPTED FOR ATTACHMENT TO A MAGNETIC AND/OR A NON-MAGNETIC MATERIAL OR SURFACE - The present invention describes a window covering which is useful for securing to objects having windows without using permanent attachment devices. The window covering preferably contains a plurality of magnets arranged along the upper end and along the lower end. The magnets are arranged so that they are coupleable or securable to a metal part of a window itself or a metal surface which houses the window as well as one or more additional magnets positioned within the window covering. The window covering further comprises one or more non-magnetic surface adapters constructed and arranged to secure to at least one magnet along a first surface and to a second, non-magnetic surface along a second surface. The window covering provides at least one contact point for securing to at least one non-magnetic surface. | 09-11-2014 |
Mary E. Rudden, Denver, CO US
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20140130180 | CONTROL OF ACCESS TO FILES - A method, system and program product for using access-control lists to control access to categorized computer files. Two or more computer files are each associated with one of a set of possible classifications that fall within a single category and an access-control list associates a user with a subset of these classifications. In response to the user's request for access to one of these files, where the request specifies the requested file but does not specify the category of the requested file, the processor identifies the requested file's category based on that file's associated classifications, checks the access-control list to determine that the user is authorized to access files of the identified category, and then grants the requesting user access to the requested file. | 05-08-2014 |
20140351708 | CUSTOMIZING A DASHBOARD RESPONSIVE TO USAGE ACTIVITY - Embodiments of the present invention disclose a method, computer program product, and system for user interface customization. A computer records activity of a first computer on a user interface. The computer determines one or more repetitive activities of the first computer utilizing the recorded activity of the first computer. The computer determines a customized user interface for the first computer corresponding to the one or more repetitive activities of the first computer. In another embodiment, the computer initiates display of the customized user interface to the first computer. In another embodiment, the recorded activity of the first computer includes navigation through links in the user interface, applying filters to data in the user interface, and accessing data on the user interface. | 11-27-2014 |
20150339358 | MANAGING QUERIES IN BUSINESS INTELLIGENCE PLATFORMS - A method is provided for managing queries in business intelligence platforms. The method includes receiving, by a processor, a first query requesting data from at least one business intelligence content, the first query having a first format. The method further includes determining, by the processor, at least one requirement to complete the first query. The method further includes converting, by the processor, the first query to a second query configured to be used by an Extract, Transform, and Load (ETL) program, in response to determining that the at least one requirement exceeds a threshold, the second query having a second format. | 11-26-2015 |
Mary E. Senkus, Hudson, WI US
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20090215345 | PARTICLE-CONTAINING FIBROUS WEB - A porous sheet article comprising a self-supporting nonwoven web of polymeric fibers and at least 80 weight percent sorbent particles enmeshed in the web, the fibers having sufficiently greater elasticity or sufficiently greater crystallization shrinkage than similar caliper polypropylene fibers and the sorbent particles being sufficiently evenly distributed in the web so that the web has an Adsorption Factor A of at least 1.6×10 | 08-27-2009 |
Mary E. Suddendorf, Waconia, MN US
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20090216861 | Integrated Software Network Agent - A model for the next generation of software network agents for downloadable software is provided. The software network agent delivers a streamlined user experience that presents the user with options to try or buy. The agent may be co-branded for merchant and affiliate marketing. The agent may be integrated with a number of services, such as ecommerce systems, affiliate marketing network systems, site optimization, web analytics and email marketing systems that enable a merchant to enhance the user experience and improve marketing. A user's actions may be tracked in order to provide OEMs and retailers payout on purchase referrals to the merchant's online store. Code changes and bug fixes can be made at the server and in a timely manner with minimal impact to the various systems supporting the software activation user experience. | 08-27-2009 |
20120150644 | INTEGRATED SOFTWARE NETWORK AGENT - A model for the next generation of software network agents for downloadable software is provided. The software network agent delivers a streamlined user experience that presents the user with options to try or buy. The agent may be co-branded for merchant and affiliate marketing. The agent may be integrated with a number of services, such as ecommerce systems, affiliate marketing network systems, site optimization, web analytics and email marketing systems that enable a merchant to enhance the user experience and improve marketing. A user's actions may be tracked in order to provide OEMs and retailers payout on purchase referrals to the merchant's online store. Code changes and bug fixes can be made at the server and in a timely manner with minimal impact to the various systems supporting the software activation user experience. | 06-14-2012 |
Mary E. Tabacco, Brighton, MA US
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20090144022 | Mixed statistical and numerical model for sensor array detection and classification - A method and system for detecting and classifying biosensor and chemical sensor data includes processing data fetched from an array of sensors. A statistical analysis of the processed data is performed, to obtain statistically analyzed sensor data. A determination is made, based on the statistically analyzed sensor data, whether or not there a response signal has been generated from the array of sensors. If a response signal is determined to have been generated, a numerical pattern recognition is performed on the data collected from the array of sensors, in order to categorize the data | 06-04-2009 |
Mary E. Tishey, Valencia, PA US
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20150197657 | CONTAINER COATING SYSTEM - A multi-coat coating system having an undercoat composition and an overcoat composition, wherein the undercoat, overcoat or both the undercoat and overcoat contain a polymer having segments of a specified formula and are substantially free of polyhydric phenols having estrogenic activity greater than or equal to that of bisphenol S. The coating system is suitable for use on a food-contact surface of food or beverage containers. | 07-16-2015 |
20150203713 | STABILIZER AND COATING COMPOSITIONS THEREOF - Coating compositions that include a thermoplastic dispersion and an epoxy-functional stabilizer having polyhydric phenols that exhibit estrogenic activity less than bisphenol S. | 07-23-2015 |
Mary E. Vaman Rao, Hopkinton, MA US
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20110213021 | COMPOSITIONS AND METHODS FOR TREATING NOS-ASSOCIATED DISEASES - The disclosures herein provide lipoic acid salts, as well as polymorphs, solvates, and hydrates thereof. These salts may be formulated as pharmaceutical compositions. The pharmaceutical compositions may be formulated for oral administration, transdermal administration, or injection. Such compositions may be used to treat NOS-associated diseases such as inflammatory diseases, metabolic diseases and neurodegenerative diseases. | 09-01-2011 |
20110262976 | PRODUCTION OF R-a-LIPOIC ACID BY FERMENTATION USING GENETICALLY ENGINEERED MICROORGANISMS - This application provides systems and methods for the production of R-α-lipoic acid. Lipoic acid synthesis genes may be expressed in an acid-tolerant microorganism, such as | 10-27-2011 |
Mary E. Wilson, Bakersfield, CA US
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20150075583 | FOLDABLE ARRAY OF THREE-DIMENSIONAL PANELS INCLUDING FUNCTIONAL ELECTRICAL COMPONENTS - Embodiments disclosed herein relate to a foldable array of three-dimensional panels, which may include one or more functional electrical components. For instance, the three-dimensional multi-panel array may be reconfigured from a substantially planar configuration into a three-dimensional configuration. | 03-19-2015 |