Mcclain
Brian Mcclain, Harvard, MA US
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20160096807 | CO-CRYSTALS OF MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR - The present disclosure relates to co-crystals comprising N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and a co-former and methods for their preparation. The present disclosure further relates to pharmaceutical compositions comprising the co-crystal forms, as well as methods of treatment therewith and kits. | 04-07-2016 |
Dallas Wayne Mcclain, Leesburg, VA US
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20160034908 | Employee Certification Management System - The Employee Certification Management System allows an organization to monitor the certification records of employees. Employee records are unique and require certifications relative to the department they are working in. This system also stores required certification documents and allows them to be downloaded by employees. An employee may log on and request supervisor approval for certifications. A supervisor may log on and approve required certifications or add additional training. Reports can be displayed on screen or printed as formatted PDF files for each employee. A system administrator has full control over the system through a built in interface. | 02-04-2016 |
George Mcclain, Middletown, DE US
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20150231758 | METHOD OF MANUFACTURING CHEMICAL MECHANICAL POLISHING LAYERS - A method of making a polishing layer for polishing a substrate selected from at least one of a magnetic substrate, an optical substrate and a semiconductor substrate is provided, comprising: providing a liquid prepolymer material; providing a plurality of hollow microspheres; exposing the plurality of hollow microspheres to a carbon dioxide atmosphere for an exposure period to form a plurality of treated hollow microspheres; combining the liquid prepolymer material with the plurality of treated hollow microspheres to form a curable mixture; allowing the curable mixture to undergo a reaction to form a cured material, wherein the reaction is allowed to begin ≦24 hours after the formation of the plurality of treated hollow microspheres; and, deriving at least one polishing layer from the cured material; wherein the at least one polishing layer has a polishing surface adapted for polishing the substrate. | 08-20-2015 |
James Mcclain, Bettendorf, IA US
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20150307632 | HIGH VISCOSITY CROSSLINKED ETHOXY-STARCH - Described herein is an ethoxylated starch crosslinked with a cross linking agent having surprisingly high viscosity in water. The ethoxlylated crosslinked starch described has a degree of ethoxy substitution from 1% to 3% and the crosslinking agent is from 0.02% to 0.05% of the weight of starch. Within this narrow range of values, a 7% wt/wt aqueous solution of the crosslinked ethoxylated starch exhibits a viscosity of at least 1600 cps at 95 C. This ethoxlylated crosslinked starch is particularly useful in the formation of ceiling tiles with stucco, borax and steel wool, and should be useful in enhancing the viscosity of hydraulic fracturing fluids. | 10-29-2015 |
James B. Mcclain, Ocracoke, NC US
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20160030643 | DRUG COATED STENTS - Provided herein is a coated coronary stent including a stent framework, heparin molecules attached to the stent framework and a rapamycin-polymer coating wherein at least part of rapamycin is a crystalline form. In one embodiment, the rapamycin-polymer coating comprises one or more resorbable polymers. Methods for preparing stents are also disclosed. | 02-04-2016 |
20160095726 | STENTS HAVING CONTROLLED ELUTION - Provided herein is a device comprising: a. stent; b. a plurality of layers on said stent framework to form said device; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form. | 04-07-2016 |
20160101220 | COATINGS CONTAINING MULTIPLE DRUGS - A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents. | 04-14-2016 |
Matt Mcclain, Austin, TX US
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20150229662 | METHOD AND APPARATUS FOR IDENTIFYING A THREATENING NETWORK - A system and method for identifying a threatening network is provided. The system comprises a network movement before/after algorithm that provides a graphical plot of changes in networks' communications activity from before to after a key event occurs, so that an analyst is able to identify anomalous behavior; a network progression algorithm that provides a graphical plot to analyze behavior in small increments of time without specification or emphasis upon a particular event, so that the analyst is able to see a trend in behavioral changes; a statistical network anomaly ranking algorithm that provides as output a ranked list of the networks; and an anomaly trend graphs algorithm that analyzes and visualizes the networks' anomaly scores over time, so that the analyst is able to see which networks are consistently suspicious, which networks accumulate more suspiciousness in response to an event, and which networks are trending toward more suspiciousness. | 08-13-2015 |
Nancy Mcclain, Medina, OH US
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20160057974 | Method and Apparatus for Animal Grooming - The present invention is a method and apparatus for safely and securely holding and supporting an animal while it is being groomed. The disclosed apparatus can have multiple support members that wrap around an animal, passing under the animal's belly, around the hips and shoulders, and up over the back where it can be secured to a frame or post to keep the animal stable and supported, without restraining the animal by the neck, while undergoing a grooming procedure. The cutouts and support members that make up the leg holes in the apparatus can be lined with a soft material, such as fleece, to provide comfort and prevent chafing to the animal's skin during the procedure. | 03-03-2016 |
Patrick James Mcclain, Galveston, TX US
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20150265021 | USER HEAD SUPPORT APPARATUS FOR A WASH BASIN - A support apparatus for a head of a user placed in a wash basin maintains the neck of the user in a neutral position, thereby minimizing head or neck injuries. The support apparatus includes a base member with a cushion member to receive the head of the user and a support arm to contact a side wall of the wash basin, a leg member with a shaft rotatably mounted to the base member, the leg member able to adjust so the distance between the base member and the leg member is sufficient to enable the bottom portion of the leg member to be in contact with a drain of the wash basin, and a locking mechanism slidably mounted to the shaft to secure the leg member to the base member. | 09-24-2015 |
Sean Mcclain, Somerville, MA US
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20150268050 | Navigation by Ocean Surface Topography - Methods and apparatus ascertain a geographic position based on topographic contours of ocean surfaces. Observed ocean topographic contours are matched to predicted ocean topography and/or ocean topographic information stored in a database. Such systems and methods do not necessarily require INS, GPS, RF beacons, optical beacons or celestial sightings. These systems and methods may be used as references to correct INS. These systems and methods may be used to ascertain a geographic location of an aircraft, spacecraft, watercraft, landcraft (vehicle), person or the like. Similarly, these systems and methods may be used as part of a guidance system for guiding a craft to a destination. These systems and methods may be used in tandem with, or as backups for, other types of navigation or guidance systems or as one input to a navigation filter. | 09-24-2015 |
Sean Mcclain, Portland, OR US
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20150225731 | INDUCIBLE COEXPRESSION SYSTEM - The present invention is an inducible coexpression system, capable of controlled induction of expression of each gene product. | 08-13-2015 |
20150353940 | VECTORS FOR USE IN AN INDUCIBLE COEXPRESSION SYSTEM - The present invention provides expression vectors for use in an inducible coexpression system, capable of controlled induction of expression of each gene product. | 12-10-2015 |