Patent application number | Description | Published |
20090131401 | Transcription factor modulating compounds and methods of use thereof - Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms. | 05-21-2009 |
20090131481 | Transcription Factor Modulating Compounds and Methods of Use Thereof - Substituted benzimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of using substituted benzimidazole compounds, in, e.g., reducing virulence and infectivity, inhibiting biofilms and treating bacterial infections are also provided. | 05-21-2009 |
20090170812 | Transcription factor modulating compounds and methods of use thereof - Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms. | 07-02-2009 |
20110059962 | TRANSCRIPTION FACTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF - Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of using substituted benzimidazole compounds, in, e.g., reducing virulence and infectivity, inhibiting biofilms and treating bacterial infections, are also provided. | 03-10-2011 |
20110218168 | SUBSTITUTED POLYAMINES AS INHIBITORS OF BACTERIAL EFFLUX PUMPS - Disclosed are methods of treating bacterial infections including those caused by multidrug resistant bacteria using polyamine efflux pump inhibiting compounds, including for example N-benzylated polyazaalkanes, N-benzylated polyaminoalkanes, or mixed N-benzylated poly(aza/amino)alkanes, optionally in combination with other drugs such as antibiotics, as well as pharmaceutical compositions thereof. | 09-08-2011 |
20120209003 | METHODS FOR IDENTIFYING AND USING MarR FAMILY POLYPEPTIDE BINDING COMPOUNDS - Methods for identifying MarR family inhibiting compounds are described. The methods include the use of computer aided rational based drug design programs and three dimensional structures of MarR family polypeptides. | 08-16-2012 |
20130109617 | SUBSTITUTED TETRACYCLINE COMPOUNDS FOR TREATMENT OF BACILLUS ANTHRACIS INFECTIONS | 05-02-2013 |
20130144038 | CRYSTAL STRUCTURE OF A MarR FAMILY POLYPEPTIDE - The crystal structure of the product, crystals of the MarR protein, a regulator of multiple antibiotic resistance in | 06-06-2013 |