Patent application number | Description | Published |
20100087514 | METHOD AND MEANS FOR TREATMENT OF OSTEOARTHRITIS - The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inducing anabolic stimulation of chondrocytes, including cartilage formation enhancing pharmaceutical compositions, and the use thereof in treating and/or preventing a disease involving a systemic or local decrease in mean cartilage thickness in a subject. | 04-08-2010 |
20120190727 | METHOD AND MEANS FOR TREATMENT OF OSTEOARTHRITIS - The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inducing anabolic stimulation of chondrocytes, including cartilage formation enhancing pharmaceutical compositions, and the use thereof in treating and/or preventing a disease involving a systemic or local decrease in mean cartilage thickness in a subject. | 07-26-2012 |
20140107181 | METHODS AND MEANS FOR TREATMENT OF OSTEOARTHRITIS - The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inducing anabolic stimulation of chondrocytes, including cartilage formation enhancing pharmaceutical compositions, and the use thereof in treating and/or preventing a disease involving a systemic or local decrease in mean cartilage thickness in a subject. | 04-17-2014 |
Patent application number | Description | Published |
20110172765 | Heart Valve Prosthesis and Methods of Manufacture and Use - A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis. | 07-14-2011 |
20110313515 | REPLACEMENT HEART VALVE - A replacement heart valve can have an expandable frame configured to engage a native valve annulus. A valve body can be mounted onto the expandable frame to provide functionality similar to a natural valve. The valve body has an upstream end and a downstream end, and a diameter at the downstream end is greater than a diameter at the upstream end. | 12-22-2011 |
20120215303 | REPLACEMENT HEART VALVE AND METHOD - A replacement heart valve has an expandable frame configured to engage a native valve annulus and a valve body mounted to the expandable frame. The valve body can have a plurality of valve leaflets configured to open to allow flow in a first direction and engage one another so as to close and prevent flow in a second direction, the second direction being opposite the first direction. | 08-23-2012 |
20120259409 | Heart Valve Prosthesis and Methods of Manufacture and Use - A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis. | 10-11-2012 |
20130144378 | METHOD OF SECURING AN INTRALUMENAL FRAME ASSEMBLY - A replacement heart valve has an expandable frame configured to engage a native valve annulus and a valve body mounted to the expandable frame. The valve body can have a plurality of valve leaflets configured to open to allow flow in a first direction and engage one another so as to close and prevent flow in a second direction, the second direction being opposite the first direction. | 06-06-2013 |
20150127095 | Heart Valve Prosthesis and Methods of Manufacture and Use - A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis. | 05-07-2015 |
Patent application number | Description | Published |
20150270949 | PROTECTING A WHITE-BOX IMPLEMENTATION AGAINST ATTACKS - A method of performing a keyed cryptographic operation mapping an input message to an output message, wherein the cryptographic operation includes at least one round including a non-linear mapping function configured to map input data to output data, including: splitting the input data into n split input data, wherein the splitting of the input data varies based upon the value of the input message; inputting each split input data into the non-linear mapping function to obtain n split output data, wherein a combination the n split output data indicates an output data, wherein the output data results when the input data is input to the non-linear mapping function. | 09-24-2015 |
20150270950 | SPLITTING S-BOXES IN A WHITE-BOX IMPLEMENTATION TO RESIST ATTACKS - A method of performing a keyed cryptographic operation mapping an input message to an output message, wherein the input message comprises m input data and the output message comprises m output data and wherein the cryptographic operation includes at least one round and the cryptographic operation specifies a substitution box for mapping input data into output data, including: transforming each of the m input data into n output data using n split substitution boxes, wherein the n split substitution boxes sum to the specified substitution box; and mixing and combining the m×n output data. | 09-24-2015 |
20150270951 | SECURITY MODULE FOR SECURE FUNCTION EXECUTION ON UNTRUSTED PLATFORM - A method of performing a secure function on data inputs by a security module, including: receiving an encrypted data value by the security module; decrypting the encrypted data value using a white-box decryption block cipher and encoding the decrypted data value, wherein the data value is invisible to an attacker; performing a function on the encoded data value and producing an encoded result of the function, wherein the data value and the result are invisible to the attacker; decoding the encoded result of the programmed function and then encrypting the result using a white-box encryption block cipher, wherein the result is invisible to the attacker. | 09-24-2015 |