Molloy
Anne Molloy, Dublin IE
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20080213775 | METHODS AND MATERIALS FOR IDENTIFYING POLYMORPHIC VARIANTS, DIAGNOSING SUSCEPTIBILITIES, AND TREATING DISEASE - The invention is directed to materials and methods associated with polymorphic variants in two enzymes involved in folate-dependent and one-carbon metabolic pathways: MTHFD1 (5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase, 10-formyltetrahydrofolate synthetase) and methylenetetrahydrofolate dehydrogenase (NADP+dependent) 1-like (MTHFD1L). Diagnostic and therapeutic methods are provided involving the correlation of polymorphic variants in MTBFD1, MTHFD1, and other genes with relative susceptibility for various pregnancy-related and other complications. | 09-04-2008 |
20110177958 | METHODS AND MATERIALS FOR IDENTIFYING POLYMORPHIC VARIANTS, DIAGNOSING SUSCEPTIBILITIES, AND TREATING DISEASE - The invention is directed to materials and methods associated with polymorphic variants in two enzymes involved in folate-dependent and one-carbon metabolic pathways: MTHFD1 (5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase, 10-formyltetrahydrofolate synthetase) and methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (MTHFD1L). Diagnostic and therapeutic methods are provided involving the correlation of polymorphic variants in MTHFD1, MTHFD1, and other genes with relative susceptibility for various pregnancy-related and other complications. | 07-21-2011 |
Christopher Molloy, New Plymouth NZ
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20100068543 | MODIFICATION OF WOOD WITH HYDROPHILIC PREPOLYMERS - A composition for modification of wood products is disclosed. The composition contains a prepolymer formed by the reaction of a polyfunctional hydrophilic polymer of high molecular weight and a crosslinking agent. The composition may also contain a prepolymer formed by the reaction of a sugar and a crosslinking agent. Modification of the wood product may result in one or more of: improved stiffness, strength, surface hardness, dimensional stability, water resistance, flame retardancy, and biological resistance. | 03-18-2010 |
20120003491 | Insecticidal Composition and Method - A composition for surface treatment of timber and wood products that provides protection against insect damage to all surfaces without any need for a secondary insecticide treatment of one or more new, untreated surfaces generated by post-treatment processing operations including sawing, cutting, drilling, beveling, planing, sanding and/or a combination thereof, comprising one or more non-repellent insecticides. | 01-05-2012 |
20130090238 | Synergistic Fungicidal Composition And Methods Of Use - Described is a broad spectrum, synergistic fungicidal composition when used for the preservation of a glued wood product comprising as active ingredients: | 04-11-2013 |
Darren Molloy, Galway City IE
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20140361086 | SMARTCARD WITH COUPLING FRAME AND METHOD OF INCREASING ACTIVATION DISTANCE OF A TRANSPONDER CHIP MODULE - A conductive coupling frame (CF) having two ends, forming an open loop, disposed surrounding and closely adjacent a transponder chip module (TCM), and substantially coplanar with an antenna structure (AS, LES) in the transponder chip module (TCM). A metal card body (MCB) having a slit (S) extending from a module opening (MO) to a periphery of the card body to function as a coupling frame (CF). The coupling frame (CF) may be thick enough to be non-transparent to RF at frequencies of interest. A switch may be provided to connect ends of the coupling frame (CF) across the slit (S). The transponder chip module (TCM) may comprise a laser-etched antenna structure (LES) and a non-perforated contact pad (CP) arrangement. | 12-11-2014 |
20150021403 | SMARTCARD WITH COUPLING FRAME AND METHOD OF INCREASING ACTIVATION DISTANCE OF A TRANSPONDER CHIP MODULE - A conductive coupling frame (CF) having two ends, forming an open loop having two ends or a discontinuous metal layer disposed surrounding and closely adjacent a transponder chip module (TCM, | 01-22-2015 |
Dean Molloy, Kilrush Hollymount IE
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20100161034 | STENTS WITH ATTACHED LOOPED ENDS - An open frame prosthesis is formed with looped end terminations at its proximal and distal ends. At one end of the prosthesis, the filaments or strands are welded together in pairs to form strand couplings. A plurality of loop segments are connected to the strand couplings, one loop segment for each pair of adjacent strand couplings. In one version of the prosthesis, strands at the opposite end are bent to form looped ends. In another version, loop segments are connected to pairs of strand couplings at both ends of the prosthesis. The loop segments can be connected to the couplings by welding, fusion bonds, or tubes, which are either crimped or heat shrunk. | 06-24-2010 |
20120101564 | STENTS WITH ATTACHED LOOPED ENDS - An open frame prosthesis is formed with looped end terminations at its proximal and distal ends. At one end of the prosthesis, the filaments or strands are welded together in pairs to form strand couplings. A plurality of loop segments are connected to the strand couplings, one loop segment for each pair of adjacent strand couplings. In one version of the prosthesis, strands at the opposite end are bent to form looped ends. In another version, loop segments are connected to pairs of strand couplings at both ends of the prosthesis. The loop segments can be connected to the couplings by welding, fusion bonds, or tubes, which are either crimped or heat shrunk. | 04-26-2012 |
Iarla Molloy, Craughwell IE
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20120090033 | SYSTEMS AND METHODS FOR IMPLEMENTING APPLICATION CONTROL SECURITY - Systems and methods for implementing application control security are disclosed. In one embodiment, a system includes a first device, a decrypted white-list, and an executable program. The first device may be in electrical communication with a memory containing an encrypted white-list. The encrypted white-list may be decrypted using an identifier of a second device. The executable program may be referenced in the decrypted white-list. | 04-12-2012 |
20140208107 | SYSTEMS AND METHODS FOR IMPLEMENTING APPLICATION CONTROL SECURITY - Systems and methods for implementing application control security are disclosed. In one embodiment, a system includes a first device, a decrypted white-list, and an executable program. The first device may be in electrical communication with a memory containing an encrypted white-list. The encrypted white-list may be decrypted using an identifier of a second device. The executable program may be referenced in the decrypted white-list. | 07-24-2014 |
Kevin Molloy, Richmond CA
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20100051679 | METHOD AND SYSTEM FOR INSPECTION OF TRAVELERS - A kiosk for processing arriving travelers is provided, wherein the kiosk reads information from the traveler's travel document, and either receives a completed declaration form from the traveler or poses a series of questions to the traveler. On obtaining the needed information from the traveler, the kiosk queries a government computer to obtain a code for the traveler. The code, when shown to a government official, such as a customs agent, will determine if the traveler is retained for secondary processing. | 03-04-2010 |
Mark Molloy, New South Wales AU
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20100299081 | Detection and Quantification of Polypeptides Using Mass Spectrometry - The invention relates to the detection and quantification of polypeptides using mass spectrometry. Specifically, the invention provides a method for testing whether a target polypeptide is present in a sample of a set of polypeptides, a method for deriving a value for distinguishing polypeptides of a set of polypeptides from each other, a database containing values for distinguishing each polypeptide of a set of polypeptides from each other, and an apparatus for configuring a mass scan of a mass spectrometer to test whether a target polypeptide of a set of polypeptides is present in a sample of the set. | 11-25-2010 |
Mark Molloy, North Ryde AU
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20140156206 | Detection and Quantification of Polypeptides Using Mass Spectrometry - The invention relates to the detection and quantification of polypeptides using mass spectrometry. Specifically, the invention provides a method for testing whether a target polypeptide is present in a sample of a set of polypeptides, a method for deriving a value for distinguishing polypeptides of a set of polypeptides from each other, a database containing values for distinguishing each polypeptide of a set of polypeptides from each other, and an apparatus for configuring a mass scan of a mass spectrometer to test whether a target polypeptide of a set of polypeptides is present in a sample of the set. | 06-05-2014 |
Padraig Molloy, Craughwell IE
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20120013126 | WATER ELEVATION TYPE WAVE ENERGY CONVERTER AND METHOD OF CONVERSION OF WAVE ENERGY - The present invention relates to an energy system and method suitable for converting wave energy of a body of water into movement of a drive train to capture energy comprising a vessel sitting on said body of water having a hull ( | 01-19-2012 |
Peter Molloy, New South Wales AU
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20110160072 | METHOD OF DIAGNOSING NEOPLASMS - The present invention relates generally to a nucleic acid molecule, the RNA and protein expression profiles of which are indicative of the onset, predisposition to the onset and/or progression of a large intestine neoplasm. More particularly, the present invention is directed to a nucleic acid molecule, the expression profiles of which are indicative of the onset and/or progression of a colorectal neoplasm, such as an adenoma or an adenocarcinoma. The expression profiles of the present invention are useful in a range of applications including, but not limited to, those relating to the diagnosis and/or monitoring of colorectal neoplasms, such as colorectal adenomas and adenocarcinomas. Accordingly, in a related aspect the present invention is directed to a method of screening a subject for the onset, predisposition to the onset and/or progression of a large intestine neoplasm by screening for modulation in the expression profile of said nucleic acid molecule markers. | 06-30-2011 |
Peter Molloy, Chatswood AU
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20140155280 | METHOD OF DIAGNOSING NEOPLASMS - The present invention relates generally to a method for screening a subject for the onset, predisposition to the onset and/or progression of a colorectal neoplasm by screening for modulation in the level of expression of one or more nucleic acid markers. More particularly, the present invention provides a method for screening a subject for the onset, predisposition to the onset and/or progression of a colorectal neoplasm by screening for modulation in the level of expression of one or more gene markers in membranous microvesicles. The expression profiles of the present invention are useful in a range of applications including, but not limited to, those relating to the diagnosing and/or monitoring of colorectal neoplasms, such as colorectal adenoma and adenocarcinomas. | 06-05-2014 |
Peter L. Molloy, Chatswood AU
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20090104154 | Composition and method for killing of tumours - The present invention provides a method of treating a solid tumour in a subject, the method comprising the following steps (i) delivering to the solid tumour a composition comprising an engineered ovine atadenovirus; and (ii) administering a prodrug to the subject, wherein the engineered ovine atadenovirus comprises a promoter and a gene encoding an enzyme which converts the prodrug to a cytotoxic metabolite, the gene being under control of the promoter. | 04-23-2009 |
20130059734 | Epigenetic analysis - Provided herein are methods for the analysis of methylation in nucleic acid molecules, comprising bisulfite conversion and subsequent copying or amplification in the presence of a ligand-labelled dCTP or a ligand-labelled dGTP incorporated at the site of a cytosine or complementary guanine, respectively, at positions corresponding to methylated cytosines in the bisulfite-treated nucleic acid or after the copying or amplification, subjecting the resulting nucleic acid molecules to restriction endonuclease digestion with an enzyme which comprises a cytosine nucleotide in its target recognition sequence to generate nucleic acid fragments with termini proximal or adjacent to one or more cytosines and attaching a ligand or oligonucleotide adaptor and subsequently amplifying the nucleic acid molecules. | 03-07-2013 |
Peter L. Molloy, New South Wales AU
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20090215056 | Assay for Methylation in the GST-PI Gene - A diagnostic or prognostic assay is disclosed for a disease of condition characterized by abnormal methylation of cytosine at side or sites within the glutathione-S-transferase (GST) Pi gene and/or its regulatory flanking sequences (e.g., prostate cancer and liver cancer). The assay comprises: (i) isolating DNA from said subject, and (ii) determining (e.g., by selective PCR amplification) the presence of abnormal methylation of cytosine at a site or sites within the GST-Pi gene and/or its regulatory flanking sequences. | 08-27-2009 |
20120231452 | ASSAY FOR METHYLATION IN THE GST-PI GENE - A diagnostic or prognostic assay is disclosed for a disease of condition characterized by abnormal methylation of cytosine at side or sites within the glutathione-S-transferase (GST) Pi gene and/or its regulatory flanking sequences (e.g., prostate cancer and liver cancer). The assay comprises: (i) isolating DNA from said subject, and (ii) determining (e.g., by selective PCR amplification) the presence of abnormal methylation of cytosine at a site or sites within the GST-Pi gene and/or its regulatory flanking sequences. | 09-13-2012 |
Peter Laurence Molloy, New South Wales AU
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20100233683 | AMPLIFICATION OF DNA FRAGMENTS - A method for detecting a nucleic acid molecule having a target sequence adjacent a 3′ terminus is provided. Also provided is a method for differentiating nucleic acid molecules having a target sequence adjacent a 3′ terminus from nucleic acid molecules in which the same sequence is embedded within the molecule. | 09-16-2010 |
20110098189 | METHOD OF DIAGNOSING NEOPLASMS - II - The present invention relates generally to nucleic acid molecules in respect of which changes to the DNA or to the RNA or protein expression profiles are indicative of the onset, predisposition to the onset and/or progression of a neoplasm. More particularly, the present invention is directed to nucleic acid molecules in respect of which changes to the DNA or to the RNA or protein expression profiles are indicative of the onset and/or progression of a large intestine neoplasm, such as an adenoma or an adenocarcinoma. The DNA or the expression profiles of the present invention are useful in a range of applications including, but not limited to, those relating to the diagnosis and/or monitoring of colorectal neoplasms, such as colorectal adenocarcinomas. Accordingly, in a related aspect the present invention is directed to a method of screening a subject for the onset, predisposition to the onset and/or progression of a neoplasm by screening for modulation in the DNA or the RNA or protein expression profile of one or more nucleic acid molecule markers. | 04-28-2011 |
Peter Laurence Molloy, Chatswood AU
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20130338020 | EPIGENETIC MARKERS OF COLORECTAL CANCERS AND DIAGNOSTIC METHODS USING THE SAME - The present invention relates generally to nucleic acid molecules in respect of which changes to DNA methylation levels are indicative of the onset or predisposition to the onset of a neoplasm. More particularly, the present invention is directed to nucleic acid molecules in respect of which changes to DNA methylation levels are indicative of the onset and/or progression of a large intestine neoplasm, such as an adenoma or adenocarcinoma. The DNA methylation status of the present invention is useful in a range of applications including, but not limited to, those relating to the diagnosis and/or monitoring of colorectal neoplasms, such as colorectal adenocarcinomas. Accordingly, in a related aspect the present invention is directed to a method of screening for the onset, predisposition to the onset and/or progression of a neoplasm by screening for modulation in DNA methylation of one or more nucleic acid molecules. | 12-19-2013 |
20140287940 | METHOD OF DIAGNOSING NEOPLASMS - II - The present invention relates generally to nucleic acid molecules in respect of which changes to the DNA or to the RNA or protein expression profiles are indicative of the onset, predisposition to the onset and/or progression of a neoplasm. More particularly, the present invention is directed to nucleic acid molecules in respect of which changes to the DNA or to the RNA or protein expression profiles are indicative of the onset and/or progression of a large intestine neoplasm, such as an adenoma or an adenocarcinoma. The DNA or the expression profiles of the present invention are useful in a range of applications including, but not limited to, those relating to the diagnosis and/or monitoring of colorectal neoplasms, such as colorectal adenocarcinomas. Accordingly, in a related aspect the present invention is directed to a method of screening a subject for the onset, predisposition to the onset and/or progression of a neoplasm by screening for modulation in the DNA or the RNA or protein expression profile of one or more nucleic acid molecule markers. | 09-25-2014 |
20140315203 | DNA METHYLATION IN COLORECTAL AND BREAST CANCER DIAGNOSTIC METHODS - The present invention relates generally to nucleic acid molecules in respect of which changes to DNA methylation levels are indicative of the onset or predisposition to the onset of a neoplasm. More particularly, the present invention is directed to nucleic acid molecules in respect of which changes to DNA methylation levels are indicative of the onset and/or progression of a large intestine or breast neoplasm, such as an adenoma or adenocarcinoma. The DNA methylation status of the present invention is useful in a range of applications including, but not limited to, those relating to the diagnosis and/or monitoring of colorectal or breast neoplasms, such as colorectal or breast adenocarcinomas. Accordingly, in a related aspect the present invention is directed to a method of screening for the onset, predisposition to the onset and/or progression of a neoplasm by screening for modulation in DNA methylation of one or more nucleic acid molecules. The nucleic acid molecules used for diagnostics in the present invention are sequences from LOC 100526820, subsequently named CAHM (colorectal adenocarcinoma hypermethylated). | 10-23-2014 |
Sean Molloy, Auckland NZ
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20130045517 | FERMENTATION OF WASTE GASES - The invention relates to the microbial fermentation of gaseous substrates to produce one or more products. The invention relates to the microbial fermentation of a gaseous substrate derived from the conversion of a biogas stream. The invention relates to the conversion of a biogas stream comprising methane to a gaseous substrate comprising CO and/or H2, and the production of one or more products from the microbial fermentation of said gaseous substrate. | 02-21-2013 |
20140370559 | FERMENTATION OF WASTE GASES - The invention relates to the microbial fermentation of gaseous substrates to produce one or more products. The invention relates to the microbial fermentation of a gaseous substrate derived from the conversion of a biogas stream. The invention relates to the conversion of a biogas stream comprising methane to a gaseous substrate comprising CO or CO plus H2, and the production of one or more products from the microbial fermentation of said gaseous substrate. | 12-18-2014 |
Shane Molloy, Corrandulla IE
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20100185229 | VASCULAR FILTER DEVICE - A vascular filter device ( | 07-22-2010 |
20100185230 | VASCULAR FILTER DEVICE - A vascular filter device comprises a support; and a filter comprising one or more filter elements configured to capture thrombus passing through a blood vessel. A holder holds the filter in a closed filtering state and releases to convert the filter to an open state after a period of time. The filter is adapted to retain thrombus after said conversion. In one case the filter elements are arranged to remain in a closed state after release by the holder, because they are blocked by a retained clot from opening fully, and the filter elements are biased to the open state with a bias level which is counter balanced by force exerted by a retained clot under action of blood flow. | 07-22-2010 |
Shane Molloy, County Galway IE
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20140207177 | VASCULAR FILTER DEVICE - A vascular filter device ( | 07-24-2014 |
Steve Molloy, Montreal CA
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20140122486 | AUTO-CLASSIFICATION SYSTEM AND METHOD WITH DYNAMIC USER FEEDBACK - An auto-classification system and method provides dynamic user feedback in a guide that is presented to the user. The feedback presented in the guide enables the user to refine the classification model by adding or removing exemplars, creating, editing or deleting rules, or performing other such adjustments to the classification model. This technology enhances the overall transparency and defensibility of the auto-classification process. | 05-01-2014 |
Steve Molloy, Chambly CA
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20140282910 | SYSTEMS, METHODS AND COMPUTER PROGRAM PRODUCTS FOR INFORMATION INTEGRATION ACROSS DISPARATE INFORMATION SYSTEMS - An information integration system may include a set of integration services embodied on one or more server machines in a computing environment. The set of integration services may include connectors communicatively connected to disparate information systems. The connectors may be configured for integrating data stored in the disparate information systems utilizing a common model employed by the set of integration services. The common model may overlay, augment, integrate, or otherwise utilize a content management interoperability services data model and may include common property definitions and a common security model. The common security model may include permissions particularly defined for use by the set of integration services. These common property definitions and permissions may be uniquely defined and utilized by the information integration system. | 09-18-2014 |
20150058314 | SYSTEMS, METHODS AND COMPUTER PROGRAM PRODUCTS FOR INFORMATION MANAGEMENT ACROSS DISPARATE INFORMATION SYSTEMS - An information integration system may include a set of integration services embodied on one or more server machines in a computing environment. The set of integration services may include connectors communicatively connected to disparate information systems. The connectors are configured for integrating data utilizing a common model comprising a content management interoperability services data model, common property definitions, and a common security model particularly defined for use by the set of integration services. Responsive to a user query to search disparate information systems or a subset thereof, an application may communicate metadata of interest contained in the user query to a search engine which locates, via a unified index, requested data from the disparate information systems or a subset thereof. The search engine returns search results referencing the requested data to the application which interprets the search results and displays a visualization thereof on a client device. | 02-26-2015 |
Thomas Scott Molloy, Lindfield AU
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20140343245 | Plasma Treatment of Halogenated Compounds - A method and an apparatus for the non-thermal plasma processing of halogenated compounds. A non-thermal plasma reactor ( | 11-20-2014 |