Mouz
Nicolas Mouz, Grenoble FR
Patent application number | Description | Published |
---|---|---|
20080213292 | Soluble And Stabilized Trimeric Form Of Gp41 Polypeptides - The present invention concerns a modified polypeptide containing at least an immunodominant region and the connecting loop between N- and C-helices of gp41 ectodomain of HIV-1, wherein the connecting loop includes at least a linker fragment having: —a size convenient for keeping the native conformation of the interaction between N- and C-helices, and—an hydrophily sufficient to provide a soluble and stable trimeric form to said modified polypeptide. | 09-04-2008 |
Nicolas Mouz, Saint Paul De Varces FR
Patent application number | Description | Published |
---|---|---|
20110311615 | NOVEL GP41 ANTIGENS - The present invention deals with a modified polypeptide comprising three contiguous segments N, L and C represented by the formula N−L−C and comprising: a N-helix region of gp41 (N), a C-helix region of gp41 (C), and a connecting loop comprising a synthetic linker (L) between the N and C-helices, the linker replacing amino acids 593-617 of gp41, the numbering scheme being based upon the prototypic isolate HIV-1 HxB2 Clade B strain, said polypeptide comprising the calveolin-1 neutral izing and 98.6 D epitopes, but not 2F5 and 4E10 epitopes, not the fusion peptide, the polypeptide having a minimal immunogenic cross-reactivity with human interleukin 2 (IL2). | 12-22-2011 |
20130018178 | METHOD FOR THE PURIFICATION OF HBHAAANM Laronze; AurelieAACI GrenobleAACO FRAAGP Laronze; Aurelie Grenoble FRAANM Mouz; NicolasAACI Saint Paul De VarcesAACO FRAAGP Mouz; Nicolas Saint Paul De Varces FRAANM Pech; JoanaAACI Saint EgreveAACO FRAAGP Pech; Joana Saint Egreve FR - The present invention concerns a new method for the purification of Heparin Binding Hemagglutinin (HBHA) robust and reproducible at an industrial scale. The purification is made from HBHA-producing microorganisms extracted in presence of a detergent, a solvent or a chaotropic agent, followed by a first elution on ion exchange resins. In a preferred embodiment, the elution on ion exchange resins is followed by a second chromatography on mixed mode sorbents. | 01-17-2013 |
20140093556 | Immunological Compositions Against HIV - The disclosure relates to immunological compositions for vaccinating human beings against infection by the Human Immunodeficiency Virus (HIV). | 04-03-2014 |
Nicolas Mouz, St Paul De Varces FR
Patent application number | Description | Published |
---|---|---|
20120003716 | METHOD FOR PRODUCING LIPASE, TRANSFORMED YARROWIA LIPOLYTICA CELL CAPABLE OF PRODUCING SAID LIPASE AND THEIR USES - Method for producing | 01-05-2012 |
Sebastien Mouz, Villaz FR
Patent application number | Description | Published |
---|---|---|
20150320831 | PROTEIN SLURP-1 FOR USE IN THE TREATMENT OF OCULAR DISEASES - The present invention relates to a protein comprising SEQ ID NO:1 (mature form of SLURP-1) and to a composition comprising the same for use in inducing or accelerating cicatrisation, and/or in preventing infection in the eye of a subject. | 11-12-2015 |