Muschler
George Muschler, Cleveland Heights, OH US
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20100167316 | Enrichment of Tissue-Derived Adult Stem Cells Based on Retained Extracellular Matrix Material - Methods for enriching, detecting, or using adult stem cells through the use of recognition ligands that specifically bind to ECM components retained to the surfaces of adult stem cells are described. An ECM component such as hyaluronan that is retained to the surfaces of adult stem cells when removed from animal tissues can be used to detect a diverse population of adult stem cells based on the nature of the ECM niche region in which the adult stem cells normally reside. For example, a separation method such as magnetic separation can be used to detect and isolate or enrich adult stem cells based on a recognition ligand that is specific for an ECM component that is retained to the surfaces of adult stem cells to a greater degree than to other cells in the population. | 07-01-2010 |
George F. Muschler, Cleveland Heights, OH US
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20100329536 | IMAGE ANALYSIS OF BIOLOGICAL OBJECTS - Systems and methods are described for performing image analysis. A computer-implemented method for analyzing images may include quantitatively analyzing image data to identify image objects relative to a background portion of the image according to predefined object criteria, the image data including a plurality of image objects that represent objects in a sample distributed across a substrate. The identified image objects are further clustered into groups or colonies of the identified image objects according to predetermined clustering criteria. | 12-30-2010 |
John L. Muschler, Albany, CA US
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20090155272 | Targeted pharmaceuticals and ligands - The disclosure pertains to pharmaceuticals, more specifically, to targeted diagnostic and therapeutic formulations and ligands thereof. Such methods and composition comprise antigens that are post-translationally modified compared to antigens found on a normal cell phenotype. Also provided are ligands that bind to such post-translationally modified antigens. | 06-18-2009 |
John L. Muschler, Lake Oswego, OR US
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20150374845 | COMPOUNDS THAT BIND DYSTROGLYCAN AND USES THEREOF - Disclosed herein are methods and compositions involved in identifying cells that lack apico-basal polarity as well as methods and compositions involved in selectively delivering payload molecules to cells that lack apico-basal polarity, and methods of selecting test compounds that restore apico-basal polarity. | 12-31-2015 |
Michael Muschler, Rosslau DE
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20100126217 | METHOD FOR PRODUCING A CYLINDER OF QUARTZ GLASS USING A HOLDING DEVICE AND APPROPRIATE HOLDING DEVICE FOR PERFORMING THE METHOD - A known method for producing a cylinder of quartz glass comprises a method step in which a porous SiO | 05-27-2010 |
Thomas Muschler, Ingolstadt DE
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20150130158 | Driven Axle of a Dual-Track Vehicle - A driven axle of a dual-track vehicle is provided in which a wheel-guiding control rod on the body of the vehicle or on a cross member connected to the body of the vehicle is stabilized spatially in an slightly elastic fashion via a control rod bearing on the body. The control rod of the right-hand wheel is additionally connected to the control rod of the left-hand wheel via a coupling rod. The coupling rod is exclusively supported on the left-hand and right-hand control rod, preferably in the vicinity of the respective control rod bearing on the body of the vehicle that is disposed in an offset fashion in the longitudinal direction of the vehicle relative to the associated wheel bearing. A mechanical deep-pass filter is provided in the coupling rod and/or in the connection between the coupling rod and a control rod stabilized relative thereto. | 05-14-2015 |