Niven, US
Anne Fagan Niven, St. Louis, MO US
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20090264355 | METHODS TO TREAT ALZHEIMER'S DISEASE OR OTHER DISORDERS MEDIATED BY AMYLOID-BETA ACCUMULATION IN A SUBJECT - The invention provides methods of delaying the onset, slowing the progression, preventing, or treating Alzheimers disease in a subject. In particular, the invention provides methods of modulating transport of Aβ across the blood brain barrier of the subject. | 10-22-2009 |
Anne Fagan Niven US
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20110143380 | ALZHEIMER'S DISEASE BIOMARKERS AND METHODS OF USE - The invention encompasses biomarkers for AD, a method for detecting AD, a method of monitoring AD, and a kit for quantifying biomarkers for AD. | 06-16-2011 |
Greg Niven, Santa Clara, CA US
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20080259247 | LASER BACKLIGHTING FOR DISPLAYS - Displays such as LCD panels are illuminated using frequency-doubled vertical extended cavity surface emitting lasers (VECSELs) as efficient light sources. Visible light from the VECSELs are directed to an illuminating panel using optical fibers and/or optical gratings to provide substantially uniform illumination of the illuminating panel. Visible light from the illuminating panel, which can be provided at a particular number of primary wavelengths by the VECSELs, is then used to illuminate the display. | 10-23-2008 |
Gregg Niven, Kaysvillie, UT US
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20150018814 | METHODS FOR RESHAPING CARTILAGE STRUCTURES - Described are methods and systems for reshaping a cartilage structure. Such methods comprise treating the cartilage structure with electromagnetic energy and fitting a device to the cartilage structure to retain it in the desired place, form, and/or orientation. Systems comprise an emitter of electromagnetic energy and a device to the cartilage structure to retain it in the desired place, form, and/or orientation. | 01-15-2015 |
Gregg Niven, Kaysville, UT US
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20140191518 | FENCE GATE BRACE - A gate brace is provided which allows the top rail of a fence gate to be attached to the adjacent rail of a fence section or another gate section. The brace keeps the gate from twisting, making the gate stronger and more secure. The brace prevents animals from pushing through the bottom of the gate by twisting the gate, and keeps the gate from flexing due to wind and other forces. | 07-10-2014 |
Gregg D. Niven, Kaysville, UT US
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20090046248 | Ocular scanning device with programmable patterns for scanning - A device that projects light rays and beams onto the eye in a predetermined pattern or arrangement of patterns, wherein the light rays or beams scatter in the eye tissues and which images of scatter are captured by video scanning cameras. The images are transferred into digital information for processing, storage, display or retrieval by a processing device which also determines the location, and position of the scattered light in space and prepares a mathematical representation of the light representing the shape, thickness, and relationship of the tissues of the eye. | 02-19-2009 |
20110012340 | Fluid Conduit Couplers with Depressible Latch Mechanism - A fluid conduit coupling assembly has a depressible latch mechanism that secures a first fluid conduit to a second fluid conduit via a first coupler and a second coupler. The first coupler connects to the first fluid conduit and the second coupler connects to the second fluid conduit. The depressible latch mechanism is formed by a pair of cantilevered buttons disposed in symmetrically opposed positions on one of the couplers. The cantilevered buttons have engagement lips that extend distally with catches that extend radially outward to engage a ridge formed on an interior wall of the opposing coupler. Fluid ports within the couplers interface when the couplers connect to provide fluid flow between the first and second conduits. Valves may be disposed in each of the couplers to arrest fluid flow when the couplers are detached and automatically open to allow fluid to flow when the couplers are connected. | 01-20-2011 |
20150051639 | RETAINING DEVICES, RETAINING DEVICES FOR USE IN RESHAPING EARS AND RELATED SYSTEMS AND METHODS - Retaining devices for use with ears of a subject may include a first portion configured to be secured to a subject's head and a second portion configured to position the helix of the subject's ear. Methods of reshaping tissue of a subject's ear may include performing a laser treatment on the tissue of the subject's ear and installing a retaining device on the subject's ear. | 02-19-2015 |
John Laurence Niven, Livermore, CA US
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20090289654 | SYSTEM AND METHOD FOR REDUCING TEMPERATURE VARIATION DURING BURN IN - Systems and methods for reducing temperature variation during burn-in testing. In one embodiment, power consumed by an integrated circuit under test is measured. An ambient temperature associated with the integrated circuit is measured. A desired junction temperature of the integrated circuit is achieved by adjusting a body bias voltage of the integrated circuit. By controlling temperature of individual integrated circuits, temperature variation during burn-in testing can be reduced. | 11-26-2009 |
20090316750 | SYSTEM AND METHOD FOR REDUCING TEMPERATURE VARIATION DURING BURN IN - Systems and methods for reducing temperature variation during burn-in testing. In one embodiment, power consumed by an integrated circuit under test is measured. An ambient temperature associated with the integrated circuit is measured. A desired junction temperature of the integrated circuit is achieved by adjusting a body bias voltage of the integrated circuit. By controlling temperature of individual integrated circuits, temperature variation during burn-in testing can be reduced. | 12-24-2009 |
Ralph Niven, Burlingame, CA US
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20100029551 | Treatment Of Inflammatory Lung Conditions With Aerosolized Macrolide Antibiotics - Provided herein are pharmaceutical compositions comprising an anti-inflammatory macrolide compound suitable for aerosolized administration to the lungs by inhalation, and methods of treating inflammatory lung conditions, particularly those characterized by chronic inflammation, by administering an aerosolized anti-inflammatory macrolide compound to the lungs by inhalation. Also provided are unit dose formulations of an anti-inflammatory macrolide for aerosolized administration to the lungs by inhalation. Advantageously, the described methods and compositions allow for the targeted, localized delivery of anti-inflammatory macrolide compounds throughout the lungs without significant systemic absorption or deposition. | 02-04-2010 |
Ralph Niven, Half Moon Bay, CA US
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20110318277 | TACROLIMUS COMPOSITIONS FOR AEROSOL ADMINISTRATION - The present disclosure relates generally to highly concentrated macrolide solutions for aerosol administration, and related methods of producing and administering the same. In one aspect, provided herein is a receptacle containing a highly concentrated solution of a macrolide compound such as tacrolimus, where the solution exhibits long-term stability in a pMDI canister and achieves high respirable fractions when actuated, among, other features. In yet another aspect, provided is a composition suitable for aerosol administration comprising tacrolimus dissolved in an ethanol-liquified propellant mixture, characterized by a tacrolimus concentration of greater than 0.15 weight percent (w/w) and comprising no more than about 10 weight percent (w/w) ethanol. | 12-29-2011 |
20130012869 | NASAL IRRIGATION SYSTEMS - Nasal irrigation systems for irrigating and/or rinsing a subject's nasal cavity are disclosed herein. Irrigation fluid may be drawn through the nasal cavity while utilizing a staged treatment procedure which allows for an initial infusion or flushing of irrigation fluid, circulation of the fluid, and subsequent flushing of the effluent from the nasal cavity. The system allows for reversible flow of the fluid during irrigation as well as use of vibration to disrupt debris within the nasal cavity to facilitate the mixing and removal of the debris. Additionally, peristaltic flow of the irrigation fluid may be used to facilitate contact between the fluid and debris during fluid circulation. Moreover, the irrigation fluid may also incorporate air or a gas into the fluid flow to create discrete volumes or boluses of pressured fluid to further facilitate thorough irrigation of the nasal cavity. | 01-10-2013 |
Ralph Niven, San Carlos, CA US
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20130184198 | Pulmonary Surfactant Formulations - Synthetic pulmonary surfactant compositions comprising dipalmitoyl phosphatidylcholine, phosphatidylglycerol, and essentially neutral lipid, and having essentially no 1-palmitoyl 2-oleoyl phosphatidylglycerol and essentially no palmitic acid are provided. Methods for treating respiratory disease are also provided comprising administering a therapeutically effective amount of a synthetic pulmonary surfactant comprising dipalmitoyl phosphatidylcholine, phosphatidylglycerol, and essentially neutral lipid, and having essentially no 1-palmitoyl 2-oleoyl phosphatidylglycerol and essentially no palmitic acid. | 07-18-2013 |
Ralph W. Niven, Half Moon Bay, CA US
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20120020887 | Use of Simple Amino Acids to Form Porous Particles - Particles having a tap density of less than 0.4 g/cm | 01-26-2012 |
20130071440 | USE OF SIMPLE AMINO ACIDS TO FORM POROUS PARTICLES - Particles having a tap density of less than 0.4 g/cm | 03-21-2013 |
Vernon Niven, Los Altos Hills, CA US
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20090270166 | Personalized Transaction Management and Media Delivery System - Media data for a live event such as a horse race, associated real-time data, and contextually related asynchronous data are presented to an end user. A content delivery network distributes the media data and a server distributes the associated real-time data. A time synchronization module combines the media data with the associated real-time data based on a correspondence of temporal data and outputs an integrated data feed. A contextual relating module identifies asynchronous data stored by an asynchronous data storage as contextually relevant to the integrated data feed, outputs the contextually relevant asynchronous data, and records the integrated data feed and contextually relevant asynchronous data for playback as an integrated data combination. A client device executes an application for presenting to the end user the data included in the integrated data feed output by the time synchronization module along with contextually relevant asynchronous data output by the contextual relating module. | 10-29-2009 |