Patent application number | Description | Published |
20080297802 | DETECTING ELEMENT, DETECTING DEVICE, AND METHOD OF PRODUCING THE DETECTING ELEMENT - A detecting element and a detecting device having high sensitivity, and a production method thereof are provided. The detecting element for detecting a target substance in a sample includes a substrate and a metal structure. The substrate has a pore in which the thickness direction of the substrate corresponds to the depth direction of the pore and in which part of the substrate forming the pore constitutes part of the outer surface of the substrate. The metal structure exists in the pore, and has a ring shape. | 12-04-2008 |
20080316486 | TARGET SUBSTANCE-DETECTING APPARATUS AND TARGET SUBSTANCE-DETECTING METHOD - A target substance-detecting apparatus comprises a target substance-detecting element comprising metal structures, a light irradiation section for irradiating the target substance-detecting element with a light, a light-polarizing section which polarizes the irradiating light and separates an output light emitted from the target substance-detecting element into a first polarized light and a second polarized light, first and second light-receiving sections for outputting first and second signals according to intensity of the first and second polarized lights, respectively; and a control section which determines peaks of absorbances of the first and second polarized lights by measuring the absorbances from the first and second signals respectively, and controls the target substance-detecting element so that the peak values of the first and second absorbances can be maximized and minimized respectively by controlling a incidence angle of formed by a vibration direction of the incident light and a main axis of the target substance-detecting element. | 12-25-2008 |
20100097612 | DEVICE AND METHOD FOR ACQUIRING INFORMATION ON OBJECTIVE SUBSTANCE TO BE DETECTED BY DETECTING A CHANGE OF WAVELENGTH CHARACTERISTICS ON THE OPTICAL TRANSMITTANCE - An information-acquiring device for acquiring information on an objective substance to be detected, which is provided with a sensing element that has a surface capable of fixing the objective substance to be detected thereon, and makes applied light change its wavelength characteristics in response to the fixed state of the objective substance to be detected onto the surface, a light source, and light-receiving means for receiving light emitted from the light source through the sensing element, has the light-receiving means and the light source arranged on the same substrate so that the light which has been emitted from the light source and has been transmitted through the sensing element can be led to the light-receiving means, and has means for varying the wavelength regions of each light incident on each of a plurality of the light-receiving means installed in an optical path from the light source to the light-receiving means. | 04-22-2010 |
20100182610 | OPTICAL TOMOGRAPHIC IMAGING APPARATUS - In an optical tomographic imaging apparatus in which a tomographic image is acquired using an interference light between a return beam of a first measuring beam and a first reference beam traveling on a beam path having first beam path length changing unit thereon, an optical interferometer detects movement of the inspection object by using an interference light between a return beam of a second measuring beam from a movement detection position and a second reference beam traveling on a beam path having second beam path length changing unit thereon; and positional misplacement correcting unit changes the beam path length of the first reference beam based on the moving amount detected by the optical interferometer, wherein the beam path lengths of the two reference beams can be changed by a mechanism, thus further reducing deformation of an acquired image in an eye ball depth direction caused by a back and forth motion. | 07-22-2010 |
20100182612 | OPTICAL TOMOGRAPHIC IMAGING APPARATUS - Provided is an optical tomographic imaging apparatus which enables simplification and cost reduction without reducing accuracy when moving part of an object is moved in an optical axis direction of measuring beam. The apparatus using return beam of measuring beam reflected or scattered by an object and reference beam reflected by a reference mirror to image the tomographic image, includes: a reflecting position controlling device for controlling the reflecting position of the reference mirror; a detecting device for a position in a moving part having an optical system for observing the moving part illuminated by an optical system imaging the same on an area sensor based on the Scheimpflug principle and detects position information that the moving part is moved in the direction; and a device for driving the reflecting position controlling device to control the optical path length of the reference beam based on the position information. | 07-22-2010 |
20110001967 | TARGET SUBSTANCE DETECTION SYSTEM - In a localized surface plasmon detection system using a metal thin film pattern, by radiating light for detection on a detecting element using an effective light source which has a peak out of an axis, the present invention strikes a balance between narrowing a peak width of a spectrum and highly efficient illumination even if it is a case of using converging or diffused light. | 01-06-2011 |
20110019195 | RECOGNITION CHIP FOR TARGET SUBSTANCE, AND DETECTION METHOD AND DEVICE FOR THE SAME - A detection device comprising a substrate comprising a plurality of objects of which properties are changed due to the contact with a target substance, means for bringing the target substance into contact with the objects, and means for detecting a change in properties of the objects caused when the target substance is brought into contact with the objects, based on light output when the objects are irradiated with light, wherein the plurality of the objects are located in the direction in which the light for irradiation travels, and the detecting means is means for detecting the change in the properties based on the summation of light output from the plurality of the objects upon irradiation with light. | 01-27-2011 |
20110032479 | IMAGE SENSING APPARATUS USING OPTICAL COHERENCE TOMOGRAPHY AND CONTROL METHOD THEREFOR - Tomographic images of a plurality of planes at a disease site of a fundus are taken exactly within a short period of time, and the tomographic images are respectively displayed so that the positional relationship thereof becomes clear. A low coherent optical tomographic image sensing apparatus for imaging a fundus includes a sensing unit which takes tomographic images of a plurality of planes intersecting each other in time division, a display unit which displays the taken tomographic images at separate sites on the identical screen, and a position indication unit which displays, in each tomographic image, an intersection position of the each tomographic image and another tomographic image intersecting each other. | 02-10-2011 |
20110058029 | EVALUATION METHOD OF TEMPLATE IMAGES AND IN VIVO MOTION DETECTING APPARATUS - Multiple template images to be evaluated are used to carry out pattern matching with multiple images, correlation coefficients among the multiple template images are computed based on the results of the pattern matchings, and the template images are evaluated based on the computation result. As a result, the template images can be evaluated in the selection of template images used for pattern matching. | 03-10-2011 |
20110058718 | EXTRACTING METHOD AND APPARATUS OF BLOOD VESSEL CROSSING/BRANCHING PORTION - It is an object of the invention to provide a method of extracting a crossing/branching portion of a blood vessel from a fundus image of the eye at a high probability. The crossing/branching portion of the blood vessel is extracted from the fundus image under such conditions that three or more blood vessels run on an outer circumferential portion of an extraction candidate region and that a coordinate average of a plurality of blood vessels in the outer circumferential portion exists in a center portion of the extraction candidate region. | 03-10-2011 |
20110176107 | OPTICAL TOMOGRAPHIC IMAGING APPARATUS AND CONTROL METHOD FOR THE SAME - There is provided an optical tomographic imaging apparatus for imaging a tomographic image capable of setting characteristics of an optical system to accommodate to different positions on an object. The apparatus using an OCT system, includes: a scanning device for scanning measuring beams, an irradiating device for irradiating a different irradiation area on the object with the measuring beams scanned by the scanning device, an adjusting device for adjusting an irradiation position on the object of the measuring beams irradiated by the irradiating device, and a detecting device for detecting each combined beam produced from light interference between each of the return beams and the reference beams, characterized in that: the detecting device includes spectroscopy devices and a sensor, and a spectral width of the combined beam acquired with the sensor through the spectroscopy devices is set at a different spectral width by the spectroscopy devices. | 07-21-2011 |
20110267580 | CHARACTERISTIC IMAGE EXTRACTION METHOD AND OPHTHALMOLOGIC APPARATUS - Provided is an ophthalmologic apparatus for detecting an eye movement from movements of a plurality of characteristic points within a fundus image. It is determined whether or not the plurality of characteristic points are included in a new fundus image when a position of a fixation index is changed, based on a relationship between a displacement amount of the fixation index and positions of the characteristic points within a fundus plane. If it is determined that at least one of the plurality of characteristic points is not included in the new fundus image, new characteristic points are extracted from a limited range within a new fundus plane image. Accordingly, the characteristic points can be efficiently reacquired for eye movement detection performed when an imaging target region of an eye to be inspected is changed by the fixation index. | 11-03-2011 |
20110267581 | OPHTHALMOLOGIC APPARATUS AND OPHTHALMOLOGIC OBSERVATION METHOD - To accurately detect a movement of an object based on an image distorted by the movement of an eye to be inspected, which is acquired by a scanning imaging system, provided is an ophthalmologic apparatus including: an extraction means for extracting a plurality of characteristic images from a first fundus image of the eye to be inspected; a fundus image acquisition means for acquiring a second fundus image of the eye to be inspected during a period different from a period during which the first fundus image is acquired; and a calculation means for calculating at least a rotation of movements of the eye to be inspected based on the plurality of characteristic images and the second fundus image. | 11-03-2011 |
20120002166 | OPHTHALMOLOGIC APPARATUS AND OPHTHALMOLOGIC SYSTEM - Provided are a fundus imaging apparatus and a fundus imaging method capable of alleviating loads on an operator and a patient in fundus imaging and of acquiring a high-resolution fundus image. The fundus imaging apparatus having a tracking function is configured to: determine whether or not a template is recorded based on specific information of an eye to be inspected ( | 01-05-2012 |
20120002214 | OPTICAL TOMOGRAPHIC IMAGING APPARATUS AND CONTROL METHOD THEREFOR - There are provided an optical tomographic imaging apparatus which detects an amount of movement of an object during imaging to reduce a deformation or a displacement in a depth direction in an acquired image. The apparatus using interference beams obtained by combining each return beam with each reference beam, the return beams being obtained by scanning the object with measuring beams, including: a unit adapted to scan the object with the measuring beams; a unit adapted to irradiate the object with the measuring beams such that regions of the object irradiated with each measuring beams are partially overlapped; a unit adapted to calculate a positional difference in a depth direction between obtained tomographic images of the overlapped parts of the regions; and a unit adapted to compute an amount of movement of the object based on the calculated positional difference in the depth direction. | 01-05-2012 |
20120026463 | OPTICAL COHERENCE TOMOGRAPHIC IMAGING APPARATUS - Optical coherence tomographic imaging apparatus creating tomographic image of inspection object includes light splitting means for splitting light from light source into a single reference light and a single sample light, optical path length changing means for changing optical path length of the single reference light, reference light splitting means for splitting the single reference light whose optical path length is changed into a plurality of reference lights, sample light splitting means for splitting the single sample light into a plurality of sample lights, irradiation means for irradiating the inspection object by leading the plurality of sample lights thereto, interference signal forming means for combining returning lights of the plurality of the sample lights from the inspection object irradiated by the irradiation means with the plurality of reference lights passed through the reference-light path, and interference signal obtaining means for obtaining an interference signal from the interference signal forming means. | 02-02-2012 |
20120092677 | IMAGE PICKUP APPARATUS AND IMAGE PICKUP METHOD USING OPTICAL COHERENCE TOMOGRAPHY - The present invention relates to an apparatus having a simple configuration capable of correctly detecting malfunction of an OCT apparatus by detecting the states of a light source and a sensor. | 04-19-2012 |
20120294500 | OPHTHALMOLOGIC IMAGING APPARATUS - Provided is an ophthalmologic imaging apparatus suppressing the effect of a motion artifact caused by a movement of an eye to be inspected, comprising: a scanning unit for scanning, with first and second measuring beams, at least a part of an overlap area of scan areas thereof in an inspected eye, at different times, respectively; an image acquiring unit for acquiring first and second images of the inspected eye based on first and second return beams resulting from the first and second measuring beams being applied via the scanning unit and reflected by the inspected eye; an identification unit for identifying an image including a motion artifact from each of the first and second images; and an image forming unit for forming an image of the inspected eye based on the first and second images other than the images identified by the identification unit. | 11-22-2012 |
20130021575 | OPTICAL TOMOGRAPHIC IMAGING APPARATUS - Provided is an optical tomographic imaging apparatus which enables simplification and cost reduction without reducing accuracy when moving part of an object is moved in an optical axis direction of measuring beam. The apparatus using return beam of measuring beam reflected or scattered by an object and reference beam reflected by a reference mirror to image the tomographic image, includes: a reflecting position controlling device for controlling the reflecting position of the reference mirror; a detecting device for a position in a moving part having an optical system for observing the moving part illuminated by an optical system imaging the same on an area sensor based on the Scheimpflug principle and detects position information that the moving part is moved in the direction; and a device for driving the reflecting position controlling device to control the optical path length of the reference beam based on the position information. | 01-24-2013 |
20130093997 | OPTICAL COHERENCE TOMOGRAPHY AND METHOD THEREOF - The image sensing apparatus comprises a first scan unit for scanning light from an OCT light source and light from an SLO light source in a first direction of a test object, and a second scan unit for scanning the light from the OCT light source in a second direction different from the first direction of the test object. The image sensing apparatus acquires tomographic images of the test object along the first direction when the first scan unit scans the light from the OCT light source, and acquires cross-over images of the test object corresponding to the tomographic images when the first scan unit scans the light from the SLO light source. | 04-18-2013 |
20130250238 | IMAGE SENSING APPARATUS USING OPTICAL COHERENCE TOMOGRAPHY AND CONTROL METHOD THEREFOR - Tomographic images of a plurality of planes at a disease site of a fundus are taken exactly within a short period of time, and the tomographic images are respectively displayed so that the positional relationship thereof becomes clear. A low coherent optical tomographic image sensing apparatus for imaging a fundus includes a sensing unit which takes tomographic images of a plurality of planes intersecting each other in time division, a display unit which displays the taken tomographic images at separate sites on the identical screen, and a position indication unit which displays, in each tomographic image, an intersection position of the tomographic image and another tomographic image intersecting one another. | 09-26-2013 |