Orentas
Leonard Linas Orentas, South Riding, VA US
Patent application number | Description | Published |
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20100274836 | Internet Profile Service - Systems and methods for creating and using a domain profile include identifying a status of a first page associated with a domain. The first page is retrieved and additional pages from the domain are identified based on hyperlinks from the first page. The status of the additional pages is identified and the hyperlinks are prioritized based on the status and/or a comparison with predetermined data. Content is extracted from the first page and selected pages from among the additional pages. The specific additional pages may be selected based on the prioritization. The retrieved content may be processed through a signature marker set to determine a contextual match. A purpose of the domain is determined according to the status of the first page, the status of the additional pages and results of the processing of the content. The domain profile can be displayed, stored, sent and/or searched to identify web sites or attributes of interest. | 10-28-2010 |
Rimas J. Orentas, Chevy Chase, MD US
Patent application number | Description | Published |
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20140274909 | ANTI-CD22 CHIMERIC ANTIGEN RECEPTORS - The disclosure provides a chimeric antigen receptor (CAR) comprising a) an antigen binding domain of HA22, a transmembrane domain, and an intracellular T cell signaling domain; or b) an antigen binding domain of BL22, a transmembrane domain, and an intracellular T cell signaling domain comprising CD28 and/or CD137. Nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed. | 09-18-2014 |
Rimas J. Orentas, Washington, DC US
Patent application number | Description | Published |
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20150299317 | M971 CHIMERIC ANTIGEN RECEPTORS - The invention provides a chimeric antigen receptor (CAR) comprising an antigen binding domain comprising SEQ ID NOs: 1-6, a transmembrane domain, and an intracellular T cell signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed. | 10-22-2015 |