Päivi
Paivi Alajuuma, Valkeakoski FI
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20120107376 | METHOD FOR IMPROVING BIOAVAILABILITY OF LATANOPROST - The present invention relates to a method for improving ocular bioavailability of latanoprost by adding an organic amine to an aqueous eye drop composition containing latanoprost. The invention further relates to an aqueous eye drop composition in which a better ocular bioavailability of latanoprost is achieved by adding an organic amine, and to a method for treating occular hypertension and glaucoma by administering said composition to a subject in need of such treatment. | 05-03-2012 |
Paivi Liesi, Helsinki FI
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20080249021 | BIOLOGICALLY ACTIVE PEPTIDES AND THEIR USE FOR REPAIRING INJURED NERVES - The present invention relates to biologically active peptides derived from the neurite outgrowth-promoting domain of laminin-1, i.e. the γ1 -chain of laminin-1. These peptides include the decapeptide RDIAEIIKDI (SEQ ID NO:1) and the truncated peptides derived therefrom comprising the biologically active domain thereof, the tripeptide KDI. The invention is directed to the biologically active tripeptide motif KDI, and to its use in promoting regeneration of neuronal or non-neuronal tissues and, in specific, to its use in the treatment of spinal cord injuries. | 10-09-2008 |
Paivi Maeaettae, Imatra FI
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20090152333 | Method for Manufacturing a Board Tray, a Blank for the Tray, and a Tray Obtained by the Method - The invention relates to a method for manufacturing a board tray ( | 06-18-2009 |
Paivi Törmä, Espoo FI
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20100045989 | Method and device for monitoring the condition of a medium - The invention relates to a method for monitoring the condition of a medium in a channel, based on the transmission/emission of light, in which | 02-25-2010 |
Paivi Törmä, Espoo FI
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20090310138 | Method and device for monitoring the condition of a medium - The invention relates to a method for monitoring the condition of a medium, based on the transmission/emission of light in a channel, in which | 12-17-2009 |
20100045989 | Method and device for monitoring the condition of a medium - The invention relates to a method for monitoring the condition of a medium in a channel, based on the transmission/emission of light, in which | 02-25-2010 |
Paivi Vuorio, Turku FI
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20090081126 | Novel fully human anti-VAP-1 monoclonal antibodies - Novel fully human anti-VAP-1 antibodies and fragments thereof are disclosed. Nucleic acids encoding anti-VAP-1 antibodies or fragments thereof, as well as expression vectors and host cells incorporating these nucleic acids for the recombinant expression of anti-VAP-1 antibodies are also given. Pharmaceutical compositions comprising said antibodies and therapeutic uses thereof are also disclosed. | 03-26-2009 |
Päivi Aakko-Saksa, Porvoo FI
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20130199481 | GASOLINE COMPOSITIONS AND METHOD OF PRODUCING THE SAME - Gasoline fuel and method of making and using it. The fuel comprises from 5 to 20 vol.-% paraffinic hydrocarbons originating from biological oils, fats, or derivatives or combinations thereof. Further, it comprises oxygenates, such as ethanol present in a concentration of about 5 to 15 vol.-%; or iso-butanol present in a concentration of 5 to 20 vol.-%, preferably about 10 to 17 vol.-%; or ETBE present in a concentration of 7 to 25 vol.-%, preferably about 15 to 22 vol.-%. The bioenergy content of the gasoline is at least 14 Energy equivalent percentage (E | 08-08-2013 |
Päivi Aakko-Saksa, Porvoo FI
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20130199481 | GASOLINE COMPOSITIONS AND METHOD OF PRODUCING THE SAME - Gasoline fuel and method of making and using it. The fuel comprises from 5 to 20 vol.-% paraffinic hydrocarbons originating from biological oils, fats, or derivatives or combinations thereof. Further, it comprises oxygenates, such as ethanol present in a concentration of about 5 to 15 vol.-%; or iso-butanol present in a concentration of 5 to 20 vol.-%, preferably about 10 to 17 vol.-%; or ETBE present in a concentration of 7 to 25 vol.-%, preferably about 15 to 22 vol.-%. The bioenergy content of the gasoline is at least 14 Energy equivalent percentage (E | 08-08-2013 |
Päivi Hautamäki, Ilmarinen FI
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20100004339 | Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists - The invention relates to (hetero)arylsulfonylamino based peptidomimetics of formula (I), wherein R1, R2, R3, A, B, D, Q, k and n are defined as disclosed, or a pharmaceutically acceptable salt or ester thereof. Compounds of formula (I) possess high affinity and selectivity for the somatostatin receptor subtypes SSTR1 and/or SSTR4 and can be used for the treatment or diagnosis of diseases or conditions wherein an interaction with SSTR1 and/or SSTR4 is indicated to be useful. | 01-07-2010 |
Päivi Hautamäki, Ilmarinen FI
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20100004339 | Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists - The invention relates to (hetero)arylsulfonylamino based peptidomimetics of formula (I), wherein R1, R2, R3, A, B, D, Q, k and n are defined as disclosed, or a pharmaceutically acceptable salt or ester thereof. Compounds of formula (I) possess high affinity and selectivity for the somatostatin receptor subtypes SSTR1 and/or SSTR4 and can be used for the treatment or diagnosis of diseases or conditions wherein an interaction with SSTR1 and/or SSTR4 is indicated to be useful. | 01-07-2010 |
Päivi Heimala, Espoo FI
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20120058506 | MICRONEEDLE - The application relates to microfluidic needles and their manufacturing methods. The microfluidic needle comprises an interface portion containing at least one fluid communication channel, an elongated needle portion ( | 03-08-2012 |
Päivi Heimala, Vtt FI
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20120115243 | SAMPLE PORT, MULTI-LAYER FILTER, SAMPLING METHOD, AND USE OF A SAMPLE PORT IN SAMPLING - The invention relates to a sample port, filter, and sampling method. The sample port according to the invention comprises a body equipped with an internal cavity and two plungers arranged moveably in this, which can be pressed against each other in the internal cavity, in order to compress a sample, and at least one of which plungers can be moved into a reactor, in order to collect a sample. The sample port also comprises a sample chamber, which is formed by the space remaining between the internal cavity and the plungers, and at least one sample-container connection connected in connection with the internal cavity, in order to collect the sample from sample chamber. In addition, the sample port has filter means adapted to at least either plunger for separating the liquid component of the sample from the solid component and means for leading the liquid component of the sample out of the sample chamber. | 05-10-2012 |
Päivi Kivikytö-Reponen, Tampere FI
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20100025512 | MULTIMATERIAL WEAR PART OF A VERTICAL SHAFT IMPACTOR - A wear part of a vertical shaft impactor consisting of at least two or a plurality of materials, whereby the wear part comprises a base part composed of a polymer material, having wear resistant inserts attached to the base part. | 02-04-2010 |
Päivi Kivikytö-Reponen, Tampere FI
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20100025512 | MULTIMATERIAL WEAR PART OF A VERTICAL SHAFT IMPACTOR - A wear part of a vertical shaft impactor consisting of at least two or a plurality of materials, whereby the wear part comprises a base part composed of a polymer material, having wear resistant inserts attached to the base part. | 02-04-2010 |
Päivi Laakso, Ilmarinen FI
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20100048549 | Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 - The invention relates to (hetero)arylsulfonylamino based peptidomimetics of formula (I), wherein A, D, E, J, Q1 R1, R2, R3, p and j are defined as disclosed, or a pharmaceutically acceptable salt or ester thereof. Compounds of formula (I) possess high affinity and selectivity for the somatostatin receptor subtypes sst | 02-25-2010 |
Päivi Liitti, Turku FI
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20100204442 | Luminescent lanthanide (III) chelates, chelating agents and conjugates derived thereof - This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained. | 08-12-2010 |
Päivi Liitti, Turku FI
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20100204442 | Luminescent lanthanide (III) chelates, chelating agents and conjugates derived thereof - This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained. | 08-12-2010 |
Päivi Määtä, Imatra FI
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20110135793 | PACKAGE FOR READY-PREPARED FOODS - The invention relates to a package for ready-prepared foods, which comprises a dish ( | 06-09-2011 |
Päivi Myllärinen, Helsinki FI
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20140220178 | CHEESE AND PREPARING THE SAME - The present invention relates to a process for producing cheese, comprising the steps of: providing a first raw material liquid; providing a second raw material liquid; treating the first raw material liquid with a protein crosslinking enzyme to provide an enzyme-treated raw material liquid; mixing the enzyme-treated raw material liquid with the second raw material liquid to provide cheese milk; processing the cheese milk into cheese. The process produces cheese in improved yields while retaining the organoleptic properties of cheese unchanged. The invention further relates to cheese treated with a protein crosslinking enzyme, having the moisture on a fat-free basis of 67% or less and a protein profile of cheese has proteins of molecular weight of less than 66 kDa. | 08-07-2014 |
20140234484 | PRODUCT AND PROCESS FOR ITS MANUFACTURE - The invention relates to a process for the preparation of a soured milk product by means of physical modification of milk raw material and a crosslinking enzyme that strengthens the texture. The invention also relates to a milk product that contains physically modified milk raw material fat globules and has been treated with a crosslinking enzyme. | 08-21-2014 |
20140287098 | LIQUID ENZYME FORMULATION AND A PROCESS FOR ITS PREPARATION - The present invention relates to a liquid enzyme formulation, particularly to a liquid and stable formulation comprising a crosslinking enzyme and/or an enzyme modifying milk proteins. Particularly the present invention relates a liquid and stable transglutaminase formulation. In addition, the present invention relates to a method for preparing a liquid enzyme formulation. | 09-25-2014 |
Päivi Myllärinen, Helsinki FI
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20120058224 | PRODUCT AND PROCESS FOR ITS PREPARATION - The invention relates to a low-energy, low-fat or fat-free, high-protein soured or unsoured product prepared by means of a crosslinking enzyme, and to a process for the preparation thereof. | 03-08-2012 |
Päivi Peltomäki, Helsinki FI
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20100143907 | METHODS AND USES INVOLVING GENETIC ABNORMALITIES AT CHROMOSOME 12 - The present invention relates to the fields of genetics and oncology and provides methods for predicting and identifying tumors of epithelial origin. Specifically, the present invention relates to a novel method of predicting tumor initiation, tumor progression and/or carcinomas, the method comprising detecting genetic abnormality associated with tumors of epithelial origin. The present invention further relates to a novel method of identifying an individual with potential for developing carcinoma, the method comprising detection of genetic abnormalities. The present invention also relates to a method of predicting the progression of carcinomas and the transformation thereof to an aggressive variant, the method comprising detection of genetic abnormalities, which indicate the probability to develop carcinoma. The present invention also relates to a use of specific chromosomal region, a gene or a fragment thereof, and/or genetic markers for predicting tumor initiation, tumor progression and/or carcinoma. The present invention also relates to a use of specific chromosomal region or a gene or a fragment thereof in therapy, for the development of therapy, and for the preparation of a medicament for treating tumors of epithelial origin. | 06-10-2010 |
Päivi Peltomäki, Helsinki FI
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20100143907 | METHODS AND USES INVOLVING GENETIC ABNORMALITIES AT CHROMOSOME 12 - The present invention relates to the fields of genetics and oncology and provides methods for predicting and identifying tumors of epithelial origin. Specifically, the present invention relates to a novel method of predicting tumor initiation, tumor progression and/or carcinomas, the method comprising detecting genetic abnormality associated with tumors of epithelial origin. The present invention further relates to a novel method of identifying an individual with potential for developing carcinoma, the method comprising detection of genetic abnormalities. The present invention also relates to a method of predicting the progression of carcinomas and the transformation thereof to an aggressive variant, the method comprising detection of genetic abnormalities, which indicate the probability to develop carcinoma. The present invention also relates to a use of specific chromosomal region, a gene or a fragment thereof, and/or genetic markers for predicting tumor initiation, tumor progression and/or carcinoma. The present invention also relates to a use of specific chromosomal region or a gene or a fragment thereof in therapy, for the development of therapy, and for the preparation of a medicament for treating tumors of epithelial origin. | 06-10-2010 |
20130029337 | METHODS AND USES INVOLVING GENETIC ABNORMALITIES AT CHROMOSOME 12 - The present invention relates to the fields of genetics and oncology and provides methods for predicting and identifying tumors of epithelial origin. Specifically, the present invention relates to a novel method of predicting tumor initiation, tumor progression and/or carcinomas, the method comprising detecting genetic abnormality associated with tumors of epithelial origin. The present invention further relates to a novel method of identifying an individual with potential for developing carcinoma, the method comprising detection of genetic abnormalities. The present invention also relates to a method of predicting the progression of carcinomas and the transformation thereof to an aggressive variant, the method comprising detection of genetic abnormalities, which indicate the probability to develop carcinoma. The present invention also relates to a use of specific chromosomal region, a gene or a fragment thereof, and/or genetic markers for predicting tumor initiation, tumor progression and/or carcinoma. The present invention also relates to a use of specific chromosomal region or a gene or a fragment thereof in therapy, for the development of therapy, and for the preparation of a medicament for treating tumors of epithelial origin. | 01-31-2013 |
Päivi Peltomäki, Helsingin Yliopisto FI
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20140220559 | METHOD TO DETERMINE DNA MISMATCH REPAIR FUNCTION - This invention relates to a quantitative method for determining whether a human subject has an impaired DNA mismatch repair function; providing a diagnostic sample taken from said human and producing a nuclear extract from said sample; providing MMR proficient and MMR deficient nuclear extracts as positive and negative controls, respectively; combining each nuclear extract with at least one mismatch bearing substrate DNA molecule; performing a mismatch repair assay; and determining whether said sample nuclear extract is capable of repairing said substrate DNA molecule; wherein said sample comprises normal, non-malignant constitutive cells, such as fibroblasts. The invention further relates to a kit providing necessary reagents for use in said method. | 08-07-2014 |
Päivi Rousu, Kotka FI
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20100240112 | Process for Preparing a Sugar Product - The invention relates to a method for producing sugars, such as glucose, by fractionating lignocellulose-containing biomass. The sugar product thus obtained is useful for the manufacture of bioethanol and other chemicals. | 09-23-2010 |
Päivi Rousu, Kotka FI
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20100240112 | Process for Preparing a Sugar Product - The invention relates to a method for producing sugars, such as glucose, by fractionating lignocellulose-containing biomass. The sugar product thus obtained is useful for the manufacture of bioethanol and other chemicals. | 09-23-2010 |
Päivi Sarmala, Rajamaki FI
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20100213130 | SEPARATION PROCESS - The present invention relates to a chromatographic separation process for fractionating solutions containing sugars, sugar alcohols, sugar acids and/or betaine by utilizing fractions comprising parts of the separation profile as a substituent of the eluent in a novel and inventive manner. The starting solutions are typically multicomponent plant-based extracts and hydrolysates, stillages, and fermentation products and derivatives thereof. The process prow vides improved separation capacity and separation efficiency without affecting the yield or purity of product components, such as sugars, sugar alcohols, sugar acids, and betaine. The process can especially be applied to sequential SMB separation systems. | 08-26-2010 |
20120010429 | SEPARATION PROCESS - The present invention relates to a method of separating betaine and at least one other component from a sugar beet based fermentation solution. The invention is based on the use of a combination of SAC resins and WAC resins in a specific order and in specified proportions in a chromatographic SMB separation system. The chromatographic separation system is preferably a single integrated SMB system comprising both SAC and WAC resin beds. | 01-12-2012 |
Päivi Sarmala, Rajamaki FI
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20100213130 | SEPARATION PROCESS - The present invention relates to a chromatographic separation process for fractionating solutions containing sugars, sugar alcohols, sugar acids and/or betaine by utilizing fractions comprising parts of the separation profile as a substituent of the eluent in a novel and inventive manner. The starting solutions are typically multicomponent plant-based extracts and hydrolysates, stillages, and fermentation products and derivatives thereof. The process prow vides improved separation capacity and separation efficiency without affecting the yield or purity of product components, such as sugars, sugar alcohols, sugar acids, and betaine. The process can especially be applied to sequential SMB separation systems. | 08-26-2010 |
Päivi Törmä, Espoo FI
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20090310138 | Method and device for monitoring the condition of a medium - The invention relates to a method for monitoring the condition of a medium, based on the transmission/emission of light in a channel, in which | 12-17-2009 |
Päivi Varvemaa, Lappeenranta FI
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20150068112 | LIGNIN AND METHOD AND SYSTEM FOR PROCESSING LIGNIN - The invention relates to a method for processing lignin. The method includes feeding lignin material to the system, decreasing particle size of the lignin material in a grinding device in order to manufacture lignin powder having particle size distribution wherein at least 85 wt. % of the lignin agglomerates and particles are less than 300 microns, and increasing dry solids content of the lignin material at least 5 percentage units while decreasing the particle size in the grinding device. In addition, the invention relates to a system for processing lignin, a lignin powder, a method for manufacturing a product including lignin, a system for manufacturing a product including lignin and a product including lignin powder. | 03-12-2015 |
Päivi Vuorio, Turku FI
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20110117021 | FULLY HUMAN ANTI-VAP-1 MONOCLONAL ANTIBODIES - Novel fully human anti-VAP-1 antibodies and fragments thereof are disclosed. Nucleic acids encoding anti-VAP-1 antibodies or fragments thereof, as well as expression vectors and host cells incorporating these nucleic acids for the recombinant expression of anti-VAP-1 antibodies are also given. Pharmaceutical compositions comprising said antibodies and therapeutic uses thereof are also disclosed. | 05-19-2011 |