Patent application number | Description | Published |
20140314822 | DEMINERALIZED BONE FIBERS HAVING CONTROLLD GEOMETRY AND SHAPES AND METHODS THEREOF - A bone repair composition and methods thereof include elongated bone fibers made from cortical bone in which a plurality of approximately uniform bone fibers is made into various implant shapes conducive for various applications. The bone fiber compositions may be in the form of a cavity, ball, pellet, wrap, strip, cylinder, cone, putty, gel, or injectable slurry. | 10-23-2014 |
20150093429 | DEMINERALIZED BONE FIBERS HAVING CONTROLLED GEOMETRY AND SHAPES AND METHODS THEREOF - A bone repair composition and methods thereof include elongated bone fibers made from cortical bone in which a plurality of approximately uniform bone fibers is made into various implant shapes conducive for various applications. The bone fiber compositions may be in the form of a cavity, ball, pellet, wrap, strip, cylinder, cone, putty, gel, or injectable slurry. | 04-02-2015 |
Patent application number | Description | Published |
20100072377 | Methods and systems of combining magnetic resonance and nuclear imaging - A multi-modality imaging system for imaging of an object under study, e.g., a whole body or parts of the body of animals such as humans, other primates, swine, dogs, rodents (especially mice and rats), that includes a magnetic resonance imaging apparatus and a cadmium zinc telluride (CZT)-family semiconductor, single-photon imaging apparatus in close proximity such that sequential or simultaneous imaging can be done with the two modalities using the same support bed of the object under study in the same, uninterrupted imaging session. | 03-25-2010 |
20110270078 | METHODS AND SYSTEMS OF COMBINING MAGNETIC RESONANCE AND NUCLEAR IMAGING - An multi-modality imaging system for imaging of an object under study that includes a magnetic resonance imaging (MRI) apparatus and an MRI-compatible single-photon nuclear imaging apparatus imbedded within the RF coil of the MRI system such that sequential or simultaneous imaging can be done with the two modalities using the same support bed of the object under study during the imaging session. | 11-03-2011 |
20120035465 | Methods and systems of combining magnetic resonance and nuclear imaging - A multi-modality imaging system for imaging of an object under study, e.g., a whole body or parts of the body of animals such as humans, other primates, swine, dogs, or rodents, that includes a magnetic resonance imaging apparatus and a cadmium zinc telluride (CZT)-family semiconductor, single-photon imaging apparatus within a magnetic field produced by the magnetic resonance imaging apparatus such that sequential or simultaneous imaging can be done with the two modalities using the same support bed of the object under study in the same, uninterrupted imaging session. | 02-09-2012 |
20120061581 | MIXED RESOLUTION AND MULTIPLEXING IMAGING METHOD AND SYSTEM - Embodiments relate to an imaging system that includes a collimator assembly having two or more pinhole apertures therein. In one embodiment, the imaging system is configured so that two or more of the pinhole apertures have different focal lengths. The imaging system further includes a detector assembly configured to generate one or more signals in response to gamma photons that pass through the two or more pinhole apertures. Additional embodiments also relate to methods of changing collimator performance and methods of imaging a volume. | 03-15-2012 |
Patent application number | Description | Published |
20090256026 | Tilt Actuation for a Rotorcraft - An aircraft is equipped with hingeless rotors on tilting nacelles, and the tilt angles of the nacelles are controlled using either or both of an actuator and a mast moment generated by a hingeless rotor. An aircraft with two or more rotors on tilting nacelles can achieve control of yaw orientation by differential tilt of its nacelles or masts. Hingeless rotors can be manipulated to control a tilt angle of a mast by changing the rotor blade pitch to produce a mast moment. The rotor and nacelle tilt of a tiltrotor rotorcraft can be controlled and effected in order to manipulate the yaw orientation and flight mode of a rotorcraft such as a tiltrotor. The use of mast moment to control nacelle tilt angle can reduce tilt actuator loads and allows for the control of nacelle tilt even in the event of an actuator failure. | 10-15-2009 |
20100150719 | Swashplateless rotorcraft with fault tolerant linear electric actuator - An electric linear actuator is disposed to pitch a blade of a hingeless, swashplateless rotor in rotary motion. This actuator can be equipped with an electric motor advantageously made fault tolerant by winding the motor for at least 4, 5, 6, 8, or even 12 phases. Rotational motion of the electric motor is preferably converted to a translatory linear actuator output motion using a planetary roller screw coupling the rotation of the motor with pitch of the blade. The output link of the actuator can be advantageously coupled to the planetary roller screw using an internal spherical joint providing an isolated load path through the actuator. It is contemplated that a preferred rotorcraft having an electric blade pitch actuator might also be equipped with a controller that could provide the vehicle with individual blade control, in which the pitch of any rotor blade can be controlled independently of the others. | 06-17-2010 |
20110024552 | Anhedral Tip Blades for Tiltrotor Aircraft - A tiltrotor aircraft having a fixed wing and tilting rotors has a rotor blade with a shaped tip portion that provides improved hover performance. The shaped tip portion preferably has a terminal anhedral of at least 20° with respect to its stacking line, and the blade has an overall twist from root to tip of at least 20°, and a thickness ratio between 19% and 30% at a radial station of 10%. These features advantageously conspire to provide a hover figure of merit of at least 0.84 and a cruise propulsive efficiency of at least 0.85. A controller preferably limits the rotor speed in sustained airplane-mode forward flight cruise of at most 40% of a hover maximum rotor speed, and alternatively or additionally limits a rotor edgewise advance ratio to at most 0.20. | 02-03-2011 |
Patent application number | Description | Published |
20120253992 | SYSTEMS AND METHODS FOR INVENTORY GENERATION AND MANAGEMENT - A method and a system to generate and manage an inventory are provided. The system may include a memory to store an inventory having a list of items owned by a consumer. An identification module may add an item to the inventory. A collection module may collect additional data about the added item. A tracking module may collect market data about the added item. | 10-04-2012 |
20130036028 | MARKETPLACE LISTING SYSTEMS AND METHODS - A method and system generate and manage marketplace listings. In some embodiments, the method receives product information from a catalog service. The method also receives a product listing request from the catalog service that identifies a product contained in the product information. The product listing request is generated by a distributor associated with the catalog service. The method accesses distributor data associated with the distributor initiating the product listing request and accesses a listing template associated with the product information. A marketplace listing is generated based on the product, the distributor data, and the listing template. | 02-07-2013 |
20130036029 | SYSTEMS AND METHODS FOR GENERATING MARKETPLACE LISTINGS - A method and system generate and manage marketplace listings. In some embodiments, the method receives a product listing request from a catalog service that identifies a product associated with the catalog service. The product listing request is initiated by a distributor associated with the catalog service. The method identifies current listings for the product in a network-based marketplace and identifies completed listings for the product in the network-based marketplace. A price recommendation is generated for the product listing request based on the current listings and the completed listings. | 02-07-2013 |
20130339199 | INVENTORY EXCHANGE FOR MANAGING INVENTORY ACROSS MULTIPLE SALES CHANNELS - A system, method, and computer readable medium are provided to manage an inventory across multiple sales channels. A first set of items from an inventory is listed on a first sales channel according to a business rule. A second set of items from the inventory is listed on a second sales channel according to the business rule. Order events from the first sales channel and the second sales channel are tracked. The order events may indicate a transaction involving an item from the inventory. The business rule may be used to rebalance items still offered for sale on the first sales channel and the second sales channel. | 12-19-2013 |
Patent application number | Description | Published |
20110204256 | HIGH-SPEED CELLULAR CROSS SECTIONAL IMAGING - A cross sectional imaging system performs high-resolution, high-speed partial imaging of cells. Such a system may provide much of the information available from full imaging cytometry, but can be performed much more quickly, in part because the data analysis is greatly reduced in comparison with full image cytometry. The system includes a light source and a lens that focuses light from the light source onto a small spot in a scanning location. A transport mechanism causes relative motion between a cell in the scanning location and the spot. A sensor generates a signal indicating the intensity of light emanating from the cell as a result of illumination by the light source. The system repeatedly takes readings of the light intensity signal and characterizes the light intensity along a substantially linear path across the cell. | 08-25-2011 |
20120211679 | CYTOMETRY SYSTEM WITH SOLID NUMERICAL-APERTURE-INCREASING LENS - A flow cytometry system includes a flow element through which a cell is transported in a flowing fluid. The flow element includes a bore bounded by a wall. A light source is configured to illuminate the cell. An optical system receives light emanating from the cell and directs at least some of the received light to a light sensor. The optical system includes a numerical-aperture-increasing lens at a wall of the flow element. At least some of the received light passes through the numerical-aperture-increasing lens. The flow cytometry system may also include a beam splitter that directs two wavelength bands of the emanating light such that light in two wavelength band preferentially reach different sensing locations via different paths. The system may also include an optical element placed in one of the paths, shifting a focal location of the affected path to compensate for chromatic aberration of the numerical-aperture-increasing lens. | 08-23-2012 |
20120295798 | SORTING OF ADHERENT CELLS BY SELECTIVE TRANSFORMATION OF LABELS - Adherent cells bearing characteristics that are detectable only in the adherent state can be sorted on the basis of these characteristics independently of their adherent state, by applying a transformable label to the entire population of cells, both those bearing the characteristics of interest and those not, in their adherent state and identifying the locations of the cells of interest on the adherent surface. The cells of interest, or all cells other than those of interest, are then selectively treated to transform the labels and achieve differentiation between the cells of interest and the remaining cells. All cells are then released from the adherent state and sorted in the same manner as non-adherent cells but on the basis of whether the labels are transformed or not transformed. | 11-22-2012 |
20130050782 | LINE SCAN CYTOMETRY SYSTEMS AND METHODS - Systems and methods for performing cytometry using a linear light sensor. An illumination field, a line scanned by the linear light sensor, or both are swept across a cell to be imaged. Relative motion between the cell and the swept illumination may be created using a movable optical component or components, by adhering cells to a plate and transporting the plate or by other techniques. | 02-28-2013 |
20130143272 | THERMAL CYCLER WITH VAPOR CHAMBER FOR RAPID TEMPERATURE CHANGES - Rapid and uniform temperature changes in the wells of a microplate or any thin-walled plate that contains an array of reaction wells or sample receptacles are achieved by the use of heating and cooling elements with a vapor chamber interposed between such elements and the microplate. The upper surface of the vapor chamber and the underside of the sample plate in certain embodiments are complementary in shape, i.e., they have identical but oppositely directed contours in the areas around each of the sample receptacles, to provide continuous surface contact along the surface of each receptacle. In other embodiments, an intermediary plate is placed between the vapor chamber and the well plate, with the top surface of the intermediary plate being complementary in shape to the underside of the well plate. | 06-06-2013 |
Patent application number | Description | Published |
20100238442 | SERIAL-LINE-SCAN-ENCODED MULTI-COLOR FLUORESCENCE MICROSCOPY AND IMAGING FLOW CYTOMETRY - A system for performing high-speed, high-resolution imaging cytometry utilizes a line-scan sensor. A cell to be characterized is transported past a scan region. An optical system focuses an image of a portion of the scan region onto at least one linear light sensor, and repeated readings of light falling on the sensor are taken while a cell is transported though the scan region. The system may image cells directly, or may excite fluorescence in the cells and image the resulting light emitted from the cell by fluorescence. The system may provide a narrow band of illumination at the scan region. The system may include various filters and imaging optics that enable simultaneous multicolor fluorescence imaging cytometry. Multiple linear sensors may be provided, and images gathered by the individual sensors may be combined to construct an image having improved signal-to-noise characteristics. | 09-23-2010 |
20110211058 | COMPACT AUTOMATED CELL COUNTER - Biological cells in a liquid suspension are counted in an automated cell counter that focuses an image of the suspension on a digital imaging sensor that contains at least 4,000,000 pixels each having an area of 2×2 μm or less and that images a field of view of at least 3 mm | 09-01-2011 |
20140024107 | COMPACT AUTOMATED CELL COUNTER - Biological cells in a liquid suspension are counted in an automated cell counter that focuses an image of the suspension on a digital imaging sensor that contains at least 4,000000 pixels each having an area of 2×2 μm or less and that images a field of view of at least 3 mm | 01-23-2014 |
20140186938 | SERIAL-LINE-SCAN-ENCODED MULTI-COLOR FLUORESCENCE MICROSCOPY AND IMAGING FLOW CYTOMETRY - A system for performing high-speed, high-resolution imaging cytometry includes a scanning region that is illuminated by light including at least first and second wavelength bands. The system also includes a cell transport mechanism that transports a cell through the scanning region such that the cell is illuminated. The system further includes a set of at least one linear light sensor, and an optical system that selectively directs light emitted from the cell to two portions of the linear light sensor set such that emitted light in a third wavelength band is primarily directed to a first portion of the linear light sensor set, and emitted light in a fourth wavelength band is primarily directed to a second portion of the linear light sensor set. The system repeatedly takes readings of light falling on the linear light sensor set while the cell is transported through the scanning region. | 07-03-2014 |
Patent application number | Description | Published |
20090014630 | EXTENDED DYNAMIC RANGE SYSTEM DESIGN - Systems and method for detecting and measuring light emitted from a sample and having a large dynamic range, e.g., a range of luminous intensity covering six or more orders of magnitude, that may be difficult to fully detect using a single detector with a limited detection range. Simultaneous measurement of the emitted light in two intensity ranges is performed using two detectors, e.g., one including a photomultiplier tube (PMT) and the other including a solid state detector such as a photodiode. A beam splitting element directs light emitted from a sample under investigation to both detectors simultaneously such that a portion of the light impinges on the first detector and a second portion of the light impinges on the second detector. A processor receives output signals from the two detectors and provides an output representing the luminous intensity of the sample over a detection range greater than the detection range of each individual detector, thereby providing a detection system having an enhanced dynamic range. | 01-15-2009 |
20100133427 | EXTENDED DYNAMIC RANGE LIGHT DETECTION SYSTEMS AND METHODS - Systems and methods for detecting and measuring light emitted from a sample and having a large dynamic range, e.g., a range of luminous intensity covering six or more orders of magnitude, that may be difficult to fully detect using a single detector with a limited detection range. Simultaneous measurements of the emitted light in two intensity ranges are performed using two detectors, e.g., one including a photomultiplier tube (PMT) and the other including a solid state detector such as a photodiode. A beam splitting element directs light emitted from a sample under investigation to both detectors simultaneously such that a portion of the light impinges on the first detector and a second portion of the light impinges on the second detector. A processor receives output signals from the two detectors and provides an output representing the luminous intensity of the sample over a detection range greater than the detection range of each individual detector, thereby providing a detection system having an enhanced dynamic range. | 06-03-2010 |