Pilon, US
Anthony R. Pilon, Lancaster, CA US
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20080228413 | SYSTEMS AND METHODS FOR PREDICTING ACOUSTIC SIGNATURES - A system for determining an acoustic signature of a device is disclosed that includes a computer processor operable to determine strength and location of shock wave sound signals based on propagation of sound waves generated by the device. The strength and location of the shock wave signals are modified due to dissipation and dispersion effects in a non-uniform atmosphere. The shock wave signals are separated into even and odd numbered signals, and oscillations in the signals are smoothed by averaging even and odd numbered shock signals. | 09-18-2008 |
20120255806 | NOISE REDUCTION OF SUPERSONIC JET ENGINES - A jet engine adapted for reducing far-field noise levels is disclosed. The jet engine has a plurality of flap assemblies that are disposed around a perimeter of an exhaust port of the jet engine. Each flap assembly is movable between a first position and a second position. The jet engine also includes a plurality of actuators respectively coupled to the plurality of flap assemblies. Each actuator is configured to selectively move the coupled flap assembly between the first and second positions. The jet engine also includes a controller that is coupled to each actuator. The controller is configured to cause at least one actuator to move the coupled flap assembly between the first and second positions at a determined frequency. | 10-11-2012 |
Anthony Richard Pilon, Lancaster, CA US
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20140284395 | GAS TURBINE EXHAUST NOISE REDUCTION - A gas turbine jet noise reduction apparatus including a variable geometry gas turbine engine nozzle comprising a circumferentially distributed array of nozzle flap panels supported for alternate collective splaying and gathering motion, with the collective splaying motion of the flap panels being from a narrow position defining a minimum cross-sectional area at a nozzle exit plane, to a wide position defining a maximum cross-sectional area at the nozzle exit plane. A plurality of nozzle seal panels is supported in a circumferentially distributed array within the array of nozzle flap panels. A seal panel actuator is operatively engageable with the seal panels to deflect the seal panels radially inward into respective deployed positions to reduce jet noise by increasing exhaust stream mixing with ambient air. | 09-25-2014 |
Aprile L. Pilon, Gaithersburg, MD US
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20090029917 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF FIBROTIC CONDITIONS & IMPAIRED LUNG FUNCTION & TO ENHANCE LYMPHOCYTE PRODUCTION - The present invention provides methods and compositions to treat fibrotic conditions, to increase lymphocyte production in vivo, and to improve and/or normalize lung function, pulmonary compliance, blood oxygenation, and blood pH to inhibit inflammatory processes to stimulate or inhibit pro-inflammatory and immune cells, and to inhibit migration of vascular endothelial cells. The invention contemplates the administration of human uteroglobin, native or recombinant, as a means of achieving these ends. Specifically, it has been found that uteroglobin inhibits cell adhesion to fibronectin, increases lymphocyte production in vivo, and improves and/or normalizes lung function, pulmonary compliance, blood oxygenation, and blood pH, and inhibits inflammatory process. In addition it has been found that uteroglobin can stimulate or inhibit pro-inflammatory and immune cells and inhibitor migration of vascular endothelial cells. | 01-29-2009 |
20100183640 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF FIBROTIC CONDITIONS AND IMPAIRED LUNG FUNCTION AND TO ENHANCE LYMPHOCYTE PRODUCTION - The present invention provides methods and compositions to treat fibrotic conditions, to increase lymphocyte production in vivo, and to improve and/or normalize lung function, pulmonary compliance, blood oxygenation, and blood pH to inhibit inflammatory processes to stimulate or inhibit pro-inflammatory and immune cells, and to inhibit migration of vascular endothelial cells. The invention contemplates the administration of human uteroglobin, native or recombinant, as a means of achieving these ends. Specifically, it has been found that uteroglobin inhibits cell adhesion to fibronectin, increases lymphocyte production in vivo, and improves and/or normalizes lung function, pulmonary compliance, blood oxygenation, and blood pH, and inhibits inflammatory process. In addition it has been found that uteroglobin can stimulate or inhibit pro-inflammatory and immune cells and inhibitor migration of vascular endothelial cells. | 07-22-2010 |
20120231997 | RECOMBINANT HUMAN CC10 PROTEIN FOR TREATMENT OF INFLUENZA - Methods of using recombinant human CC10 (rhCC10), also known as recombinant human uteroglobin, to reduce virus titers in the tissues of patients, particularly influenza titers in lung tissues are provided. RhCC10 may be used as a therapeutic in the treatment, cure, or prevention of viral infection, particularly influenza infection. More particularly, methods, including broadly the critical dosage ranges of rhCC10, intravenous and intranasal route of administration, which may be administered to treat, cure or prevent influenza infection are provided. Further provided are compositions useful in the foregoing methods and in administering rhCC10 to humans. | 09-13-2012 |
20130261047 | METHODS AND COMPOSITIONS FOR THE REDUCTION OF NEUTROPHIL INFLUX AND THE TREATMENT OF BRONCHOPULMONARY DISPLASIA, RESPIRATORY DISTRESS SYNDROME, CHRONIC LUNG DISEASE, PULMONARY FIBROSIS, ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE - The present invention relates generally to the use of recombinant human CC10 (rhCC10), also known as recombinant human uteroglobin, for use as a therapeutic in the treatment of Respiratory Distress Syndrome (RDS), Bronchopulmonary dysplasia (BPD), chronic lung disease and/or pulmonary fibrosis, Asthma and Chronic Obstructive Pulmonary Disease (COPD). More particularly, the invention provides methods, including broadly the critical dosage ranges of rhCC10, which may be administered to safely and effectively treat the aforementioned conditions. The invention further provides a composition useful in administering rhCC10 to humans. | 10-03-2013 |
Aprile L. Pilon, Rockville, MD US
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20140274915 | Methods of Use for Recombinant Human Secretoglobins - Methods of synthetically producing, formulating and using secretoglobins SCGB1A1, SCGB3A2, and SCGB3A1 are provided. Methods of using secretoglobins SCGB1A1, SCGB3A2, and SCGB3A1 as therapeutic agents to affect long term patient outcomes, such as preventing severe respiratory exacerbations of underlying conditions that require medical intervention, including hospitalization are provided. Methods of producing recombinant human secretoglobins, analytical methods, pharmaceutical compositions, and methods of use to prevent the long term sequelae of acute and chronic respiratory conditions are provided. | 09-18-2014 |
20140275477 | Modification and Compositions of Human Secretoglobin Proteins - Novel compositions of recombinant human CC10 protein have been generated by chemically modifying the pure protein in vitro. Several new synthetic preparations containing isoforms of chemically modified rhCC10 have been generated by processes that utilize reactive oxygen species and reactive nitrogen species. These preparations contain novel isoforms of rhCC10 which have been characterized with enhanced or altered biological properties compared to the unmodified protein. Preparations containing novel isoforms may be used as standards to identify and characterize naturally occurring isoforms of native CC10 protein from blood or urine and ultimately to measure new CC10-based biomarkers to assess patient disease status. These preparations may also be used to treat respiratory, autoimmune, inflammatory, and other medical conditions that are not effectively treated with the unmodified protein. | 09-18-2014 |
Aprile L. Pilon, Germantown, MD US
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20090197808 | METHODS AND COMPOSITIONS FOR THE REDUCTION OF NEUTROPHIL INFLUX AND FOR THE TREATMENT OF BRONCHPULMONARY DYSPLASIA, RESPIRATORY DISTRESS SYNDROME, CHRONIC LUNG DISEASE, PULMONARY FIBROSIS, ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE - The present invention relates generally to the use of recombinant human CC10 (rhCC10), also known as recombinant human uteroglobin, for use as a therapeutic in the treatment of Respiratory Distress Syndrome (RDS), Bronchopulmonary dysplasia (BPD), chronic lung disease and/or pulmonary fibrosis, Asthma and Chronic Obstructive Pulmonary Disease (COPD). More particularly, the invention provides methods, including broadly the critical dosage ranges of rhCC10, which may be administered to safely and effectively treat the aforementioned conditions. The invention further provides a composition useful in administering rhCC10 to humans. | 08-06-2009 |
20110240012 | RECOMBINANT HUMAN CC10 AND COMPOSITIONS THEREOF FOR USE IN THE TREATMENT OF NASAL RHINITIS - The present invention relates generally to the use of recombinant human CC10 (rhCC10), also known as recombinant human uteroglobin, for use as a therapeutic in the treatment of nasal rhinitis, nasal sinusitis, chronic rhinosinusitis, and nasal polyposis. More particularly, the invention provides methods, including broadly the critical dosage ranges of rhCC10 and intranasal route of administration, which may be administered to safely and effectively treat the aforementioned conditions. The invention further provides a composition useful in administering rhCC10 to humans. | 10-06-2011 |
Brent Pilon, Greenville, TN US
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20110278212 | SEDIMENT AND DETENTION BASIN DRAINAGE SYSTEM AND METHOD - A fluid drainage system configured for draining a basin impounding fluid and sediment, solids or the like of varying density and turbidity. The system includes a first conduit and a second conduit within or adjacent to the first conduit to form a fluid receiving chamber between the first and second conduits, each conduit having apertures therethrough, with the apertures of the first and second conduits being sized and arranged relative to one another and so configured as to preferentially discharge fluid from the top of a basin, thus providing flow conditions which inhibit the entry of sediment into the system so as to maximize the retention of sediment within the basin and reduce turbidity and Total Suspended Sediment in the discharged fluid. | 11-17-2011 |
Brent S. Pilon, Knoxville, TN US
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20140008294 | SEDIMENT AND DETENTION BASIN DRAINAGE SYSTEM AND METHOD - A fluid drainage system configured for draining a basin impounding fluid and sediment, solids or the like of varying density and turbidity. The system includes a first conduit and a second conduit within or adjacent to the first conduit to form a fluid receiving chamber between the first and second conduits, each conduit having apertures therethrough, with the apertures of the first and second conduits being sized and arranged relative to one another and so configured as to preferentially discharge fluid from the top of a basin, thus providing flow conditions which inhibit the entry of sediment into the system so as to maximize the retention of sediment within the basin and reduce turbidity and Total Suspended Sediment in the discharged fluid. | 01-09-2014 |
Charles Pilon, Saint Paul, MN US
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20130218677 | GENERATING PROMOTIONS TO A TARGETED AUDIENCE - A system generates a targeted promotion for a group of consumers in a store. The system determines the group of consumers or an audience that are within a viewable area of a display during at least a portion of a time period. The system then generates a profile for each of the consumers and, based at least on the profiles and a goal of the store, determines the targeted promotion from multiple potential promotions. The system then displays the determined promotion on the display during the time period. | 08-22-2013 |
Charles T. Pilon, Saint Paul, MN US
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20140195302 | GUIDED WALKTHROUGH PROVIDER - A system for providing a guided walkthrough of a retail store to a user. The system receives at least one criteria. The at least one criteria defines a customer segment. The customer segment corresponds to a set of customers of the store. The system also determines a representative path. The representative path is determined based upon paths previously taken through the store by the set of customers. The system also transmits instructions to guide the user along the representative path. | 07-10-2014 |
20140330659 | USING VOICE INPUT AT A MOBILE POINT OF SALE - A method, system, and computer-readable storage medium for using voice input at a mobile point-of-sale (POS) are disclosed. For example, one method involves receiving a voice input, where the receiving is performed by a mobile POS (MPOS) device. The method also involves determining, based on the voice input, whether to use voice-based processing. In response to a determination to use the voice-based processing, performing voice-based processing, including selecting a first workflow based on the voice input, and performing a first portion of the first workflow based on the voice input. The first portion of the first workflow is performed by the MPOS device. The method also includes determining whether to perform a second portion of the first workflow based on another voice input. | 11-06-2014 |
Gabriel Pilon, Fountain Valley, CA US
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20120180631 | Projectile resistant matrix for manufacture of light weight projectile resistent trauma shields without metal or ceramic plates - The present invention discloses a method of producing and application for a projectile resistant matrix that allows for manufacture of low weight projectile resistant armor trauma shields without metal or ceramic plates using projectile resistant textiles encapsulated in a composite matrix through use of injection molding process or spray-on technique as constituents of the projectile resistant trauma shield without metal or ceramic plates of the present invention. | 07-19-2012 |
Laurent G. Pilon, Sherman Oaks, CA US
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20140285061 | THERMOMECHANICAL CYCLE FOR THERMAL AND/OR MECHANICAL ENERGY CONVERSION USING PIEZOELECTRIC MATERIALS - A system for generating electrical energy includes a thermal source, an electric field source, a stress source, a piezoelectric component, and a cycle controller coupled to the thermal source, the electric field source, and the stress source. The cycle controller provides control signals to the thermal source, the electric field source, and the stress source to repeatedly cycle the piezoelectric component through the sequence: (a) application of: a first temperature, a first electric field, and a first stress; (b) application of: the first temperature, a second electric field greater than the first electric field, and the first stress; (c) application of: a second temperature, the second electric field, and a second stress greater than the first stress; and (d) application of: the second temperature, the first electric field, and the second stress. | 09-25-2014 |
Laurent G. Pilon US
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20110298333 | DIRECT CONVERSION OF NANOSCALE THERMAL RADIATION TO ELECTRICAL ENERGY USING PYROELECTRIC MATERIALS - The embodiment provided herein are directed to a pyroelectric (PE) energy converter which is capable of combining nanoscale thermal radiation and pyroelectric energy conversion for harvesting low grade waste heat. The converter advantageously makes use of the enhanced radiative heat transfer across a nanosize gap to achieve high operating frequencies or large temperature oscillations in a composite PE plate. The PE energy converter generally comprises a hot source, a cold source, and a PE plate, wherein the PE plate oscillates between the hot and cold source and the PE plate can be subjected to a power cycle in the displacement-electric field diagram. The hot and cold sources of the converter can be coated with SiO | 12-08-2011 |
Lawrence Pilon, Grand Island, NY US
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20090056577 | Compositions compatible with jet printing and methods therefor - Apparatus and methods for controlling application of a substance to a substrate involve the use of a gating agent that blocks the substance from or attracts the substance to the substrate. The apparatus and methods may utilize ink jet technology to apply the gating agent directly to the substrate or to an intermediate surface. The gating agent composition includes a nonionic surfactant, and water. The gating agent composition does not contain a discernable amount of dye, pigment or other colorant agent. | 03-05-2009 |
20090064886 | Apparatus and methods for controlling application of a substance to a substrate - Apparatus and methods for controlling application of a substance to a substrate involve the use of a functional agent that blocks the substance from or attracts the principal substance to the substrate. The apparatus and methods may utilize ink jet technology to apply the functional agent directly to the substrate or to an intermediate surface. The principal substance may be an ink, a dye, a marking substance other than an ink, or a carrier for any other type of substance. | 03-12-2009 |
20120111212 | Apparatus and Methods for Controlling Application of a Substance to a Substrate - Apparatus and methods for controlling application of a substance to a substrate involve the use of a functional agent that blocks the substance from or attracts the principal substance to the substrate. The apparatus and methods may utilize ink jet technology to apply the functional agent directly to the substrate or to an intermediate surface. The principal substance may be an ink, a dye, a marking substance other than an ink, or a carrier for any other type of substance. | 05-10-2012 |
20130120512 | Compositions Compatible with Jet Printing and Methods Therefor - Apparatus and methods for controlling application of a substance to a substrate involve the use of a gating agent that blocks the substance from or attracts the substance to the substrate. The apparatus and methods may utilize ink jet technology to apply the gating agent directly to the substrate or to an intermediate surface. The gating agent composition includes a nonionic surfactant, and water. The gating agent composition does not contain a discernable amount of dye, pigment or other colorant agent. | 05-16-2013 |
Matthew Pilon, Smethport, PA US
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20140315425 | Subsea High Voltage Terminal Assembly - A system and method are provided for a terminal assembly of a subsea motor-compressor. The terminal assembly may include a plurality of terminal ports extending through a hollow spherical body to a cavity defined therein. The terminal assembly may also include a penetrator detachably coupled with the spherical body about each of the plurality of terminal ports. The terminal assembly may further include a mounting port extending through the spherical body to the cavity defined therein. The mounting port may be configured to couple the terminal assembly with a housing of the motor-compressor. | 10-23-2014 |
Michael Pilon, Littleton, MA US
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20090050786 | Fast and Precise Time-Resolved Spectroscopy with Linear Sensor Array - Time-resolved analysis of a spectrum is performed by illuminating a one-dimensional array of charge-transfer device light-sensitive pixel cells and periodically non-destructively copying charges in the light-sensitive cells to respective storage cells (“row storage registers”) co-located with the light-sensitive cells in an integrated circuit. Information about the charges stored in at least some of the storage cells is provided to a component external to the integrated circuit. | 02-26-2009 |
Nicholas O. P. Pilon, Sebastopol, CA US
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20140180934 | Systems and Methods for Using Non-Textual Information In Analyzing Patent Matters - Aspects of the present invention comprise using non-textual information in analyses of patent matters. In embodiments, patent matter similarity may comprise a combination of two or more metrics: (a) a metric that measures the textual similarity between an input patent portfolio and patent matters; (b) a metric that measures the behavior between portfolio patents and other patent matters at issue (e.g., which patents are asserted in the same proceeding with portfolio patents); (c) a metric that measures the textual similarity between the textual description and patent matters; and (d) a metric that inspects which patent matters are placed at issue by peer companies. In embodiments, patent matter similarity may be determined using textual similarity in combination with non-textual information. | 06-26-2014 |
Roger E. Pilon, New Baltimore, MI US
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20130146720 | Two Shot Tube Retention Fastener with Anti Material Peeling Feature - A tube retention fastener includes a polymeric material body having first and second walls and a semi-circular sleeve defining a longitudinal cavity. First and second deflecting wings individually connected to one of the first or second walls are directed toward a longitudinal axis of the longitudinal cavity in a non-deflected condition. An elastically resilient material isolation member includes a first portion fixed to the semi-circular sleeve, and first and second contact ends fixed to the first and second deflecting wings. Isolation member free extending portions are positioned and freely extend between the first portion and the contact ends. First and second wing receiving cavities are created between the deflecting wings and the first and second walls in the non-deflected condition. The deflecting wings, the contact ends and the free extending portions elastically deflect into one of the wing receiving cavities when a tube is positioned between the deflecting wings. | 06-13-2013 |
20130240684 | Two Shot Tube Retention Clip with Resilient Living Hinge - A retention clip includes first and second body portions created of a first polymeric material. The body portions when angularly rotated apart define an open position, and when rotated into direct contact defining an engaged position. An isolation portion is created of a resilient second polymeric material. The isolation portion includes isolation members connected to the body portions. The isolation members are positioned facing each other when the retention clip is in the engaged position. The isolation members frictionally contact and retain a tubular shaped member in the engaged position. A living hinge integrally connects the body portions allowing the body portions to rotate with respect to each other. The living hinge provides the only connection between the body portions as the body portions transition between the open position and the engaged position. A frangible connector initially integrally connects the first and second body portions only in the open position. | 09-19-2013 |
Roger E. Pilon, Avoca, MI US
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20100207001 | Conductive And Isolated 2-Shot Tube Clamp - A clamp includes polymeric body portions connected by a living hinge. A retention section is each created in each body portion. Elastically deflectable material insert members have injection molded features adapted to engage to the retention sections. An electrically conductive material is included with the elastically deflectable material to render the clamp electrically conductive. | 08-19-2010 |
20100242231 | BREAK-AWAY BUNDLING DEVICE - A bundling device includes a molding of a polymeric material. A flexible strap includes multiple teeth each including a notch. The strap is frangible at the notch of any one of the teeth. A strap engagement portion connected to the strap includes first and second flexible wings defining a strap receiving aperture therebetween receiving the flexible strap in a first direction. The flexible wings engage successive ones of the teeth to oppose removal of the strap in an opposite second direction. The first and second flexible wings each include a first arm having a first raised portion extending into the strap receiving portion; and a second arm having a second raised portion axially displaced with respect to the first raised portion and oriented out of plane with respect to the first raised portion. | 09-30-2010 |
20110278760 | FASTENER CLIP WITH SEAL - A single-piece fastener includes a relatively hard clip and a relatively soft seal. The seal can be overmolded onto the clip. A thermal bond is formed between the seal and the clip to inhibit removal of the seal from the clip. The flexible nature of the umbrella of the clip and the seal can accommodate sealing openings in panels of varying thicknesses. | 11-17-2011 |