Patent application number | Description | Published |
20090205036 | Secure information storage and delivery system and method - A system for secure information storage and delivery includes a vault repository that includes a secure vault associated with a user, wherein the secure vault is associated with a service level including at least one of a data type or a data size limit associated with the secure vault, the secure vault being adapted to receive and at least one data entry and securely store the at least one data entry if the at least one of a size or a type of the at least one data entry is consistent with the service level. A mobile vault server coupled to the vault repository creates a mobile vault on a mobile device based on the secure vault and is capable of authenticating the mobile device based on user authentication information. The mobile vault server includes a mobile device handler that communicates with the mobile device. A synchronization utility determines whether the at least one data entry on the secure vault is transferable to or storable on the mobile vault based on at least one of the size or the type of the at least one data entry and transfers the at least one data entry from the secure vault to a corresponding data entry on the mobile vault if the at least one data entry on the secure vault is determined to be transferable to or storable on the mobile vault. | 08-13-2009 |
20120131656 | Secure Information Storage and Delivery System and Method - A system for secure information storage and delivery includes a vault repository that includes a secure vault associated with a user, wherein the secure vault is configured to receive at least one data entry. A mobile vault server coupled to the vault repository creates a mobile vault on a mobile device based on the secure vault and is capable of authenticating the mobile device based on user authentication information. The mobile vault server includes a mobile device handler that communicates with the mobile device. A synchronization utility determines whether the at least one data entry on the secure vault is transferable to or storable on the mobile vault. and transfers the data entry from the secure vault to a corresponding data entry on the mobile vault if the at least one data entry on the secure vault is determined to be transferable to or storable on the mobile vault. | 05-24-2012 |
20140165168 | Secure Information Storage and Delivery System and Method - A system for secure information storage and delivery includes a vault repository that includes a secure vault associated with a user, wherein the secure vault is associated with a service level including at least one of a data type or a data size limit associated with the secure vault, the secure vault being adapted to receive and at least one data entry and securely store the at least one data entry if the at least one of a size or a type of the at least one data entry is consistent with the service level. A mobile vault server coupled to the vault repository creates a mobile vault on a mobile device based on the secure vault and is capable of authenticating the mobile device based on user authentication information. The mobile vault server includes a mobile device handler that communicates with the mobile device. A synchronization utility determines whether the at least one data entry on the secure vault is transferable to or storable on the mobile vault based on at least one of the size or the type of the at least one data entry and transfers the at least one data entry from the secure vault to a corresponding data entry on the mobile vault if the at least one data entry on the secure vault is determined to be transferable to or storable on the mobile vault. | 06-12-2014 |
20150304297 | Secure Information Storage and Delivery System and Method - A system for secure information storage and delivery includes a vault repository that includes a secure vault associated with a user, wherein the secure vault is associated with a service level including at least one of a data type or a data size limit associated with the secure vault, the secure vault being adapted to receive and at least one data entry and securely store the at least one data entry if the at least one of a size or a type of the at least one data entry is consistent with the service level. A mobile vault server coupled to the vault repository creates a mobile vault on a mobile device based on the secure vault and is capable of authenticating the mobile device based on user authentication information. The mobile vault server includes a mobile device handler that communicates with the mobile device. A synchronization utility determines whether the at least one data entry on the secure vault is transferable to or storable on the mobile vault based on at least one of the size or the type of the at least one data entry and transfers the at least one data entry from the secure vault to a corresponding data entry on the mobile vault if the at least one data entry on the secure vault is determined to be transferable to or storable on the mobile vault. | 10-22-2015 |
Patent application number | Description | Published |
20080235712 | Hardware Object Request Broker on a Chip for Generating Separate Control and Data Channels for Improved Throughput Efficiency - A method and apparatus are disclosed for separating the functionality of middleware ( | 09-25-2008 |
20130318607 | Using Power Fingerprinting (PFP) to Monitor the Integrity and Enhance Security of Computer Based Systems - Procedures are described for enhancing target system execution integrity determined by power fingerprinting (PFP): by integrating PFP into the detection phase of comprehensive defense-in-depth security; by deploying a network of PFP enabled nodes executing untrusted devices with predefined inputs forcing a specific state sequence and specific software execution; by embedding module identification information into synchronization signaling; by combining signals from different board elements; by using malware signatures to enhance PFP performance; by automatic characterization and signature extraction; by providing secure signature updates; by protecting against side-channel attacks; performing real-time integrity assessment in embedded platform by monitoring their dynamic power consumption and comparing it against signatures from trusted code, including pre-characterizing power consumption of the platform by concentrating on trace sections carrying the most information about the internal execution status; by using PFP from sequence of bit transitions to detect deviations from authorized execution of software in a digital processor. | 11-28-2013 |
20140269284 | SYSTEM AND METHOD FOR DISTRIBUTED DATA MANAGEMENT IN WIRELESS NETWORKS - Described are systems and methods for managing data traffic to a plurality of mobile devices over a wireless network. For each mobile device, a facility is provided that is capable of:
| 09-18-2014 |
20140274104 | SYSTEM AND METHOD FOR HETEROGENOUS SPECTRUM SHARING BETWEEN COMMERCIAL CELLULAR OPERATORS AND LEGACY INCUMBENT USERS IN WIRELESS NETWORKS - Described herein are systems and methods for telecommunications spectrum sharing between multiple heterogeneous users, which leverage a hybrid approach that includes both distributed spectrum sharing, spectrum-sensing, and use of geo-reference databases. | 09-18-2014 |
20150317475 | SYSTEMS, METHODS, AND APPARATUS TO ENHANCE THE INTEGRITY ASSESSMENT WHEN USING POWER FINGERPRINTING SYSTEMS FOR COMPUTER-BASED SYSTEMS - A power fingerprinting system is adopted for assessing integrity of a target computer-based system. In one implementation, the power fingerprinting system may receive, at a first module, side-channel information of a first target component of a system, the first module being collocated with the first target component; obtain a power fingerprint for the first target component based on the side-channel information for the first target component, the power fingerprint for the first target component representing a plurality of execution statuses of the first target component; receive, at a second module, side-channel information of a second target component of the system, the second module being collocated with the second target component, the power fingerprint for the second target component representing a plurality of execution statuses of the second target component; and obtain a power fingerprint for the second target component based on the side-channel information for the second target component. | 11-05-2015 |
20160057637 | Cognitive Reconfigurable RF Technology - The present invention provides a radio architecture that contains a main radio path and a sensing path. The parameters of the main radio path are controlled by a cognitive engine. The main radio path is tuned to a desired frequency band. The sensing path is used to monitor the spectrum around the desired frequency band. To minimize effects of undesired non-linearity on sensing, sensing path may have a lower gain setting. The cognitive engine determines the optimal setting of the main RF front-end with respect to the current state of the spectrum. | 02-25-2016 |
Patent application number | Description | Published |
20080251595 | Rail anchor isolator - The present invention provides an isolator particularly adapted for use with a rail anchor utilized in an application where railroad rail is installed on concrete ties. The isolator protects the concrete tie from contact with the rail anchor caused by longitudinal movement of the rail due to train acceleration of deceleration or expansion and contraction due to temperature changes. In one embodiment, the isolator is comprised of a structural plastic material and includes a front face section and a rear face section. The front face section and rear face section each comprise a generally rectangular structure, having a top edge, bottom edge, and side edges. A center section joins the front face section and rear face section and forms part of the top of the isolator. Ribs extending from the front face and the rear face to aid in positioning the isolator. In another embodiment, the front face section and the rear face section each include positioning tabs projecting therefrom to aid in positioning the isolator. | 10-16-2008 |
20100019056 | Rail anchor isolator for railroad tie - The present invention provides an isolator particularly adapted for use with a rail anchor utilized in an application where railroad rail is installed on concrete ties. The isolator protects the concrete tie from contact with the rail anchor caused by longitudinal movement of the rail due to train acceleration of deceleration or expansion and contraction due to temperature changes. In one embodiment, the isolator is comprised of a structural plastic material and includes a front face section and a rear face section. The front face section and rear face section each comprise a generally rectangular structure, having a top edge, bottom edge, and side edges. Top and bottom sections join the front face section and rear face section and form part of the isolator. The rail anchor also comprises a support section that extends from an intersection of the rear face section with the bottom section. The rail isolator is designed to be embedded in a concrete railroad tie. | 01-28-2010 |
20100098369 | Tapered roller bearing with improved cage - A bearing assembly is provided having a roller bearing with an inner race fitted around the journal portion of an axle. An outer raceway combines with the inner raceway to receive roller elements. A backing ring is centered to the shaft fillet. Tapered roller elements are located between and contact the inner and outer raceways. A cage is comprised of an inner ring, and outer ring, and a plurality of pocket bars and support pocket bars extending between the inner and outer rings. The support pocket bars have an overall greater thickness than the pocket bars. The cage is a generally unitary structure comprised of a nylon resin material with a fiber fill. | 04-22-2010 |
Patent application number | Description | Published |
20100273212 | PP1 Ligands - The invention relates to phosphatase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate PP1 activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands, homopolyligands, and heteropolyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands. | 10-28-2010 |
20100279378 | MEK Ligands and Polynucleotides Encoding MEK Ligands - The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate MEK activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands, homopolyligands, and heteropolyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands. | 11-04-2010 |
Patent application number | Description | Published |
20100293625 | Synthetic 5'UTRs, Expression Vectors, and Methods for Increasing Transgene Expression - The present invention provides synthetic 5′UTRs comprising a first polynucleotide fragment and a second polynucleotide fragment, wherein the first polynucleotide fragment comprises at least one splice site of a first eukaryotic gene, the second polynucleotide fragment comprises at least a portion of 5′ untranslated region of a second eukaryotic gene, and the first polynucleotide fragment is located 5′ of the second polynucleotide fragment. In one embodiment, the first polynucleotide fragment comprises the second intron of a sarcoplasmic/endoplasmic reticulum calcium ATPase gene and the second polynucleotide fragment comprises at least a portion of the 5′ untranslated region (5′UTR) of a eukaryotic casein gene. The synthetic 5′UTRs are useful for increasing the expression of a transgene when positioned between a promoter and a transgene within an expression vector. The present invention also provides vectors comprising synthetic 5′UTRs and methods for increasing the expression of a transgene using synthetic 5′UTRs. | 11-18-2010 |
20110247090 | Synthetic 5'UTRs, Expression Vectors, and Methods for Increasing Transgene Expression - The present invention provides synthetic 5′UTRs comprising a first polynucleotide fragment and a second polynucleotide fragment, wherein the first polynucleotide fragment comprises at least one splice site of a first eukaryotic gene, the second polynucleotide fragment comprises at least a portion of 5′ untranslated region of a second eukaryotic gene, and the first polynucleotide fragment is located 5′ of the second polynucleotide fragment. In one embodiment, the first polynucleotide fragment comprises the second intron of a sarcoplasmic/endoplasmic reticulum calcium ATPase gene and the second polynucleotide fragment comprises at least a portion of the 5′ untranslated region (5′UTR) of a eukaryotic casein gene. The synthetic 5′UTRs are useful for increasing the expression of a transgene when positioned between a promoter and a transgene within an expression vector. The present invention also provides vectors comprising synthetic 5′UTRs and methods for increasing the expression of a transgene using synthetic 5′UTRs. | 10-06-2011 |
20140073028 | MEK Ligands and Polynucleotides Encoding MEK Ligands - The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate MEK activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands, homopolyligands, and heteropolyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands. | 03-13-2014 |
Patent application number | Description | Published |
20110055940 | Therapeutic Inhibitors of PAI-1 Function Methods of Their Use - The invention relates to mammalian PAI-I ligands and modulators. In particular, the invention relates to polypeptides, polypeptide compositions and polynucleotides that encode polypeptides that are ligands and/or modulators of PAI-I. The invention also relates to polyligands that are homopolyligands or heteropolyligands that modulate PAI-I activity. The invention also relates to ligands and polyligands localized to a region of a cell. The invention also relates to localization tethers and promoter sequences that can be used to provide spatial control of the PAI-I ligands and polyligands. The invention also relates to inducible gene switches that can be used to provide temporal control of the PAI-I ligands and polyligands. The invention also relates to methods of treating or preventing atherosclerosis. The invention also relates to methods of treating or preventing fibrosis. | 03-03-2011 |
20110197291 | Endoplasmic Reticulum Localization Signals - The invention relates to cellular localization signals. In particular, the invention relates to endoplasmic reticulum localization signals in monomeric or multimeric form. The localization signals are utilized as research tools or are linked to therapeutics. Disclosed are methods of making and using polypeptides and modified polypeptides as signals to localize therapeutics, experimental compounds, peptides, proteins and/or other macromolecules to the endoplasmic reticulum of eukaryotic cells. The polypeptides of the invention optionally include linkage to reporters, epitopes and/or other experimental or therapeutic molecules. The invention also encompasses polynucleotides encoding the localization signals and vectors comprising these polynucleotides. | 08-11-2011 |
20110268766 | Engineered Cells Expressing Multiple Immunomodulators And Uses Thereof - This invention relates to the field of therapeutics. Most specifically invention provides methods of generating in vitro engineered immune cells conditionally expressing interleukin-12 (IL-12) and one or more immunomodulators under the control of a gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals. | 11-03-2011 |
20130253167 | Endoplasmic Reticulum Localization Signals - The invention relates to cellular localization signals. In particular, the invention relates to endoplasmic reticulum localization signals in monomeric or multimeric form. The localization signals are utilized as research tools or are linked to therapeutics. Disclosed are methods of making and using polypeptides and modified polypeptides as signals to localize therapeutics, experimental compounds, peptides, proteins and/or other macromolecules to the endoplasmic reticulum of eukaryotic cells. The polypeptides of the invention optionally include linkage to reporters, epitopes and/or other experimental or therapeutic molecules. The invention also encompasses polynucleotides encoding the localization signals and vectors comprising these polynucleotides. | 09-26-2013 |
20130266947 | Methods and Compositions for Diagnosing Disease - The present invention relates to methods and compositions for diagnosing a disease or disorder in a subject by introducing into cells of the subject a diagnostic gene switch construct and monitoring expression of a reporter gene. The invention further relates to methods and compositions for monitoring the progression of a disease or disorder or the effectiveness of a treatment for a disease or disorder. | 10-10-2013 |
20130267022 | Therapeutic Inhibitors of PAI-1 Function Methods of Their Use - The invention relates to mammalian PAI-I ligands and modulators. In particular, the invention relates to polypeptides, polypeptide compositions and polynucleotides that encode polypeptides that are ligands and/or modulators of PAI-I. The invention also relates to polyligands that are homopolyligands or heteropolyligands that modulate PAI-I activity. The invention also relates to ligands and polyligands localized to a region of a cell. The invention also relates to localization tethers and promoter sequences that can be used to provide spatial control of the PAI-I ligands and polyligands. The invention also relates to inducible gene switches that can be used to provide temporal control of the PAI-I ligands and polyligands. The invention also relates to methods of treating or preventing atherosclerosis. The invention also relates to methods of treating or preventing fibrosis. | 10-10-2013 |
20140273227 | GSK3 Ligands and Polynucleotides Encoding GSK3 Ligands - The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands and polyligands that modulate GSK3 activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands and polyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands. | 09-18-2014 |
20150018521 | Endoplasmic Reticulum Localization Signals - The invention relates to cellular localization signals. In particular, the invention relates to endoplasmic reticulum localization signals in monomeric or multimeric form. The localization signals are utilized as research tools or are linked to therapeutics. Disclosed are methods of making and using polypeptides and modified polypeptides as signals to localize therapeutics, experimental compounds, peptides, proteins and/or other macromolecules to the endoplasmic reticulum of eukaryotic cells. The polypeptides of the invention optionally include linkage to reporters, epitopes and/or other experimental or therapeutic molecules. The invention also encompasses polynucleotides encoding the localization signals and vectors comprising these polynucleotides. | 01-15-2015 |
20150056631 | Methods and Compositions for Diagnosing Disease - The present invention relates to methods and compositions for diagnosing a disease or disorder in a subject by introducing into cells of the subject a diagnostic gene switch construct and monitoring expression of a reporter gene. The invention further relates to methods and compositions for monitoring the progression of a disease or disorder or the effectiveness of a treatment for a disease or disorder. | 02-26-2015 |
20150057192 | Methods for Dynamic Vector Assembly of DNA Cloning Vector Plasmids - A method for using cloning vector plasmids to produce DNA molecules, such as transgenes, in a single cloning step. The transgenes can be used for the purpose of gene expression or analysis of gene expression. The plasmid cloning vectors are engineered to minimize the amount of manipulation of DNA fragment components by the end user of the vectors and the methods for their use. Transgenes produced using the invention may be used in a single organism, or in a variety of organisms including bacteria, yeast, mice, and other eukaryotes with little or no further modification. | 02-26-2015 |
20150104874 | AKT Ligands and Polynucleotides Encoding AKT Ligands - The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate AKT activity. The ligands, homopolyligands, and heteropolyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands, homopolyligands, and heteropolyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands, homopolyligands, and heteropolyligands. | 04-16-2015 |
20160060308 | Endoplasmic Reticulum Localization Signals - The invention relates to cellular localization signals. In particular, the invention relates to endoplasmic reticulum localization signals in monomeric or multimeric form. The localization signals are utilized as research tools or are linked to therapeutics. Disclosed are methods of making and using polypeptides and modified polypeptides as signals to localize therapeutics, experimental compounds, peptides, proteins and/or other macromolecules to the endoplasmic reticulum of eukaryotic cells. The polypeptides of the invention optionally include linkage to reporters, epitopes and/or other experimental or therapeutic molecules. The invention also encompasses polynucleotides encoding the localization signals and vectors comprising these polynucleotides. | 03-03-2016 |
20160089398 | Engineered Cells Expressing Multiple Immunomodulators and Uses Thereof - This invention relates to the field of therapeutics. Most specifically invention provides methods of generating in vitro engineered immune cells conditionally expressing interleukin-12 (IL-12) and one or more immunomodulators under the control of a gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals. | 03-31-2016 |
Patent application number | Description | Published |
20080213834 | GSK3 LIGANDS AND POLYNUCLEOTIDES ENCODING GSK3 LIGANDS - The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands and polyligands that modulate GSK3 activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands and polyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands. | 09-04-2008 |
20080220475 | mTOR LIGANDS AND POLYNUCLEOTIDES ENCODING mTOR LIGANDS - The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate mTOR activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands and polyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands. | 09-11-2008 |
20090186379 | ERK ligands and polynucleotides encoding ERK ligands - The invention relates to kinase inhibitor ligands and polyligands. In particular, the invention relates to ligands and polyligands that modulate ERK activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands and polyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands. | 07-23-2009 |
20110195504 | Tubulo-Vesicular Structure Localization Signals - The invention relates to polarized cell tubulo-vesicular structure localization signals. The localization signals are utilized as research tools or are linked to polypeptides of interest or therapeutic molecules. Disclosed are methods of making and using polypeptides and modified polypeptides as signals to localize therapeutics, experimental compounds, peptides, proteins and/or other macromolecules to the tubulo-vesicular structures of polarized cells. The polypeptides of the invention optionally include linkage to reporters, epitopes and/or other experimental or therapeutic molecules. The invention also encompasses polynucleotides encoding the localization signals and vectors comprising these polynucleotides. | 08-11-2011 |
Patent application number | Description | Published |
20130244329 | mTOR Ligands and Polynucleotides Encoding mTOR Ligands - The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate mTOR activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands and polyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands. | 09-19-2013 |
20140099668 | ERK Ligands and Polynucleotides Encoding ERK Ligands - The invention relates to kinase inhibitor ligands and polyligands. In particular, the invention relates to ligands and polyligands that modulate ERK activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands and polyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands. | 04-10-2014 |
20140178931 | mTOR Ligands and Polynucleotides Encoding mTOR Ligands - The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate mTOR activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands and polyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands. | 06-26-2014 |
20150291676 | mTOR Ligands and Polynucleotides Encoding mTOR Ligands - The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate mTOR activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands and polyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands. | 10-15-2015 |
20160022766 | mTOR Ligands and Polynucleotides Encoding mTOR Ligands - The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate mTOR activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands and polyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands. | 01-28-2016 |