Rust
Alyson Rust, Suffolk GB
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20090221024 | T CELL ASSAYS - The present invention relates to novel T cell assay methods, in particular where T cell responses to test antigens are increased by removal of regulatory T cells. Novel assays where the timing of incubation with antigens or other samples is varied in order to optimize detection of T cell responses are described. The invention has particular application for measurement of human T cell responses to pharmaceuticals, allergens, irritants or other substances. | 09-03-2009 |
Alyson Jane Rust, Suffolk GB
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20090041797 | MODIFIED TOXINS - The present application relates to compositions of modified toxins exhibiting reduced immunogenicity and reduced binding to vascular endothelium or vascular endothelial cells, thereby reducing the incidence of Vascular Leak Syndrome. Also provided are polypeptide toxophores from a modified diphtheria toxin, where modifications are in at least one amino acid residue of at least one T-cell epitope. Another aspect relates to a polypeptide toxophore from a modified diphtheria toxin, where modifications are in at least one amino acid residue of at least one T-cell epitope and at least one amino acid residue of at least one VLS motif of an unmodified native diphtheria toxin. Another aspect relates to a fusion protein which comprises a modified diphtheria toxin and a non-diphtheria toxin fragment that is a cell binding portion. Another aspect relates to the use of a modified diphtheria toxin for the treatment of a malignant disease or a non-malignant disease. | 02-12-2009 |
20090221500 | MODIFIED TOXINS - The present application relates to compositions of modified toxins exhibiting reduced immunogenicity and reduced binding to vascular endothelium or vascular endothelial cells, thereby reducing the incidence of Vascular Leak Syndrome. Also provided are polypeptide toxophores from a modified diphtheria toxin, where modifications are in at least one amino acid residue of at least one T-cell epitope. Another aspect relates to a polypeptide toxophore from a modified diphtheria toxin, where modifications are in at least one amino acid residue of at least one T-cell epitope and at least one amino acid residue of at least one VLS motif of an unmodified native diphtheria toxin. Another aspect relates to a fusion protein which comprises a modified diphtheria toxin and a non-diphtheria toxin fragment that is a cell binding portion. Another aspect relates to the use of a modified diphtheria toxin for the treatment of a malignant disease or a non-malignant disease. | 09-03-2009 |
Andrew Rust, North Gower CA
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20150316594 | Energy Monitoring and Analysis System - An energy monitoring and analysis system is provided. Sensors are attached to circuit breakers to collect energy consumption data. The energy consumption data is analyzed to determine events associated with the circuit. An energy monitoring system comprising a paddle having one or more sensors can be affixed to existing circuit breakers and provide communication with the energy analysis system. From the events notifications and alerts can be generated to inform consumers such as a utility, monitoring company or end user. | 11-05-2015 |
Bernhard Rust, Bundesland CH
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20100307433 | HYDRAULICALLY OPERATED VALVE ACTUATION AND INTERNAL COMBUSTION ENGINE WITH SUCH A VALVE ACTUATION - According to the invention, recuperation may be optimised for a hydraulically-operated gas exchange valve by provision of two fluid-filled pressure chambers and a movable regulating piston with two active faces each defining one of the pressure chambers. The pressure chambers are each connected to two hydraulic valves of which the first hydraulic valves may be pressurised from a first pressure reservoir and the second hydraulic valves may be connected to a base pressure reservoir. The first hydraulic valves may furthermore be connected to a second pressure reservoir. A control or regulation device switches the valves, from a rest position in a first accelerating phase and a braking phase. The second pressure reservoir is provided as pressure buffer for providing the pressure in the first pressure reservoir and/or for providing pressure for the fuel pump and/or for the fuel supply to an internal combustion engine and/or for providing pressure for a further gas exchange valve in the same or another combustion cylinder of the internal combustion engine. | 12-09-2010 |
Daniel Alan Rust, Norwich GB
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20120176808 | LIGHTING - Emergency lighting for an aircraft has a primary power source for light units provided by the normal aircraft power supply and a secondary power source provided by power supply units operable to back-up the primary power source. Each light unit may have its own power supply unit operable to power the light unit in an emergency if the normal aircraft power supply fails or is otherwise unable to power the emergency lighting. Each power supply unit includes one or more electric double layer capacitors that are charged whenever the normal aircraft power supply is operational to provide the primary power source. The useful life of the electric double layer capacitors may be prolonged by reducing the capacitor voltage when the emergency lighting is switched off. | 07-12-2012 |
20120236554 | LIGHTING SYSTEMS - An LED light unit is provided with terminal pins at each end for fitting the light unit in place of a fluorescent tube of a fluorescent lighting fixture connected to a power source. The light unit has a circuit board with a plurality of diodes configured to provide at least one string of visible light producing LEDs and at least one string of zener diodes. The strings are driven by drive means whereby a constant input operating voltage to the light unit is provided when the light unit is used with a ballast and the power derived is dissipated in any one or more of the strings. | 09-20-2012 |
Felix Edward Joseph Rust, Katikati SE
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20090314566 | TILT APPARATUS AND METHOD FOR OPERATING IT - A tilt apparatus and method for operating it is disclosed. The tilt apparatus for a cab of a construction vehicle comprises a support frame attached to a chassis of said vehicle, the horizontal plane of said support frame being parallel to that of said chassis, a mounting attached to said cab and connected with said support frame, and configured so that the horizontal plane of said mounting can tilt about any direction of said chassis, at least one actuator having one end connected with said support frame and the other end connected with said mounting, and operating so as to tilt said mounting, at least two inclination sensors comprising at least one top sensor installed on said mounting and at least one bottom sensor installed on said support frame or said chassis and a CPU installed in said cab and receiving the continual slope information from said top and bottom sensors and controlling the operation of said actuator on the basis of said continual slope information and the relative tilted angle information between the horizontal plane of said mounting and that of said support frame or chassis. The tilt apparatus of the invention is able automatically to level the cab of vehicle whilst the vehicle is in transit. | 12-24-2009 |
Matthew J. Rust, North Vancouver CA
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20110238105 | VIVO INFLATABLE STRUCTURES, FOR EXAMPLE TO EXPAND STENTS - Multi-balloon catheter structures that are able to move with respect to one another may provide superior compliance in tortuous passages to, for example, perform angioplasty and/or expand stents. Two or more balloons may be inflated to equal pressures. A length of the balloons may be sufficiently longer than a length of a stent to accommodate axial movement of the balloons. One or more balloons may be lubricous or carry a lubricant. | 09-29-2011 |
Matthew James Rust, North Vancouver CA
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20090125094 | SHEATH FOR INTRAVASCULAR INFLATABLE STRUCTURES, FOR EXAMPLE TO EXPAND STENTS - One or more sheaths limit radial expansion of an expansion structure, for example a multi-balloon catheter structure, while not appreciably limiting bending, facilitating the use of flexible stents in tortuous passages to, for example, perform angioplasty and/or expand stents. | 05-14-2009 |
Norman Rust, Edmonton CA
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20090071751 | PORTABLE AERIAL PLATFORM - The invention is directed to a vertically and horizontally-controlled, retractable aerial platform mountable on the bed of a vehicle for supporting a person or materials. The aerial platform includes a base, at least one support arm, a first support member, a second support member, a platform, and actuation means. The aerial platform may further include a collapsible frame. The aerial platform is vertically and horizontally-controlled, allowing a workman to adjust both the height and extension distance of the platform so that work functions can be readily performed. The aerial platform is portable, compact and suitable for use in a variety of commercial vehicles. | 03-19-2009 |
Peter Rust, Graz AT
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20110291633 | Current Source Arrangement, Circuit Arrangement with the Current Source Arrangement and Method for Operating Such an Arrangement - In one embodiment, the current source arrangement comprises a current source (B), that has two output terminals ( | 12-01-2011 |
Robert William Rust, Somerset West ZA
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20140191896 | BALL SPIN RATE MEASUREMENT - Spin rate measurement utilizing periodic phase modulation of the radar Doppler signal reflected from a golf ball is described. Some embodiments provide a method to directly measure the ball spin rate caused by the symmetrical structure of the golf ball seam, using the dielectric lens effect of a practical sports ball to magnify the modulating effect of a non-homogeneous feature on the ball, and utilizing the specific pattern of modulation caused in this manner. | 07-10-2014 |
Simon Peter Rust, Berkshire GB
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20140068739 | METHOD AND SYSTEM FOR VERIFYING AN ACCESS REQUEST - A system for verifying a request for access to data is provided, the system comprising a first module and a second module. The first module is arranged to generate a password, and the second module is arranged to receive a password associated with a request for data (received at step), validate the received password, and enable access to the requested data. The system is such that the first and second modules share a secret that has been uniquely assigned thereto, the shared secret being for use in generation and validation of a said password. Furthermore, the first module is communicatively disconnected from the second module. | 03-06-2014 |
20150178494 | METHOD AND SYSTEM FOR VERIFYING AN ACCESS REQUEST - Systems and methods for use in verifying a request for access to data in a system comprising a first module having access to a first trusted indicator of time, a second module having access to an untrusted indicator of time and a computing device having access to a second trusted indicator of time. The first module generates a password using at least the first trusted indicator of time. The second module receives a password associated with the request for access to data and validates the received password using at least the untrusted indicator of time. The second module then causes a message to be transmitted to the computing device, the message comprising data indicative at least of the untrusted indicator of time used to validate the received password. The computing device then generates data indicative of a comparison between the untrusted indicator of time and the second trusted indicator of time, and uses the generated data to provide said access to data. | 06-25-2015 |
20150178518 | METHOD AND SYSTEM FOR VERIFYING AN ACCESS REQUEST - A system for verifying a request for access to data is provided, the system comprising a first module | 06-25-2015 |
Steven Rust, Cambridge GB
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20150023966 | COMBINATION THERAPIES USING ANTI-PSEUDOMONAS PSL AND PCRV BINDING MOLECULES - This disclosure relates to combination therapies comprising anti- | 01-22-2015 |
20150104450 | CTLA-4 Variants - Variants of cytotoxic T-lymphocyte antigen 4 (CTLA-4) with high affinity, potency and stability. Formulations of CTLA-4 variants at high concentration for subcutaneous or intravenous administration, e.g. at monthly or less frequent dosage intervals. Use of CTLA-4 variants for treating rheumatoid arthritis and other inflammatory disorders. Fusion of CTLA-4 with IgG Fc having improved stability and longer in vivo half-life. | 04-16-2015 |
20150284450 | COMBINATION THERAPIES USING ANTI-PSEUDOMONAS PSL AND PCRV BINDING MOLECULES - The disclosure relates to combination therapies comprising anti- | 10-08-2015 |
William L. Rust, Singapore SG
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20100247493 | Method for Identifying and Selecting Cardiomyocytes - The present invention relates to new and/or improved methods of identification and selection of cardiomyocytes from human embryonic stem (hES) cells. The method further comprises isolating the selected cardiomyocyte population. There is also provided method for the screening for cardiovascular compounds comprising subjecting the said cardiomyocyte population to test compound/s, and observing and/or interpreting a response of the cardiomyocytes to the test compound. | 09-30-2010 |