Patent application number | Description | Published |
20080286880 | Methods and Systems for Nanoparticle Enhancement of Signals - Methods and systems for utilizing metal nanoparticles to enhance optical (UV, visible, and IR, as appropriate) signals from a reporting entity are presented. The methods and systems of this invention do not require the nanoparticles to be attached or adhered to a surface, assembled in a matrix or coated with a spacer coating. | 11-20-2008 |
20090217398 | METHODS TO IDENTIFY FAT AND LEAN ANIMALS USING CLASS PREDICTORS - A combination comprising two or more polynucleotides that are differentially expressed in fat animals compared to lean animals or two or more proteins produced by the expression of such polynucleotides is disclosed. The combination and probes based upon the combination are used for formulating a prognosis that an animal is likely to become fat, developing a diagnosis that an animal is fat, screening substances to determine if they are useful for modulating the amount of adipose tissue on an animal, and detecting the differential expression of one or more genes differentially expressed in fat animals compared to lean animals in a sample. Methods for using class predictor gene profiles to identify fat and lean animals are also disclosed. | 08-27-2009 |
20100221729 | Methods for assessing Calpain 2 Resistance, Disease Progression, and Treatment Efficacy in Ovarian Cancer - The invention provides methods for predicting whether an ovarian cancer patient's tumor will be resistant to chemotherapy. The invention also provides methods for monitoring the effectiveness of treatment, particularly a chemotherapeutic treatment, in a patient treated for ovarian cancer. The invention further provides methods for treating ovarian cancer, by reducing chemotherapeutic drug resistance in said cells. In addition, the invention provides methods of screening compounds to identify tumor cell growth inhibitors in tumor cells resistant to conventional chemotherapeutic treatment regimes. | 09-02-2010 |
20100221730 | Methods for assessing SPARC Resistance, Disease Progression, and Treatment Efficacy in Ovarian Cancer - The invention provides methods for predicting whether an ovarian cancer patient's tumor will be resistant to chemotherapy. The invention also provides methods for monitoring the effectiveness of treatment, particularly a chemotherapeutic treatment, in a patient treated for ovarian cancer. The invention further provides methods for treating ovarian cancer, by reducing chemotherapeutic drug resistance in said cells. In addition, the invention provides methods of screening compounds to identify tumor cell growth inhibitors in tumor cells resistant to conventional chemotherapeutic treatment regimes. | 09-02-2010 |
20100221731 | Methods for assessing MetAP2 Resistance, Disease Progression, and Treatment Efficacy in Ovarian Cancer - The invention provides methods for predicting whether an ovarian cancer patient's tumor will be resistant to chemotherapy. The invention also provides methods for monitoring the effectiveness of treatment, particularly a chemotherapeutic treatment, in a patient treated for ovarian cancer. The invention further provides methods for treating ovarian cancer, by reducing chemotherapeutic drug resistance in said cells. In addition, the invention provides methods of screening compounds to identify tumor cell growth inhibitors in tumor cells resistant to conventional chemotherapeutic treatment regimes. | 09-02-2010 |
20110178005 | COMPOSITIONS AND METHODS FOR TREATING DISORDERS ASSOCIATED WITH OVERWEIGHT ANIMALS - The invention encompasses compositions and methods for treating disorders and diseases associated with overweight. The application also encompasses genes differentially expressed in animals and particularly to genes differentially expressed in overweight animals compared to lean animals. | 07-21-2011 |
20110183006 | COMPOSITIONS AND METHODS FOR TREATING OSTEOARTHRITIS - The present invention provides compositions and methods for treatment of abnormal conditions in a subject, wherein the abnormal condition affects the musculoskeletal joints of the subject. | 07-28-2011 |
20120283129 | COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING KIDNEY DISORDERS IN A CANINE - The present invention provides methods for: diagnosing of, devising and monitoring a treatment plan for, and monitoring the status of a kidney disorder characterized by an abnormal loss of renal function, renal failure, reduced glomerular filtration rate or glomerulonephritis, in a canine, wherein the kidney disorder is detectable by utilizing at least one relevant biomarker isolated and measured from a biological test sample taken from such canine. The invention additionally relates to compositions, reagents and kits for carrying out the specified methods. | 11-08-2012 |
20130059012 | Methods for the Diagnosis, Control and Prophylaxis of Inflammation and Mitigation of Inflammatory Conditions in Felines - The invention relates to methods of diagnosis, control and prophylaxis of inflammation and mitigation of inflammatory conditions, particularly arthritis and joint pain, in felines, comprising measuring particular inflammatory biomarkers. The invention further provides a method to treat or control inflammation comprising administering a diet comprising increased levels of one or more of DHA, EPA, methionine, manganese, vitamin C, vitamin E, and/or L-carnitine. | 03-07-2013 |
20130142894 | HEALTH SUPPLEMENT COMPOSITIONS FOR COMPANION ANIMALS AND METHODS OF USING THE SAME - Aspects of the present invention include compositions configured for maintaining health and/or treating progressive degenerative conditions, e.g., hip and joint conditions, kidney conditions, etc., in companion animals. The compositions include supplement formulations and a highly palatable edible backbone, e.g., in the form of a soft chew, tablet or drink. Supplement formulations of interest include one or more naturally occurring active agents which are effective in maintaining health and/or treating a progressive degenerative condition. Methods of maintaining health of and/or treating a companion animal for a progressive degenerative disease by administering the supplement formulations are also provided. | 06-06-2013 |
20130273196 | Pet Food Compositions for Inducing a Satiety Response - The invention relates to pet food compositions designed to induce the animal to cease feeding upon consumption of the appropriate nutritional amount. The invention further provides methods of inducing satiety response in animals and methods of controlling the amount of food intake in animals. | 10-17-2013 |
20130274335 | Pet Food Compositions and Methods for Treating Arthritis and Inflammation Associated with Arthritis - The present invention provides food compositions that are effective in treating arthritis or inflammation associated with arthritis in a companion animal, preferably a canine or feline. | 10-17-2013 |
20130280352 | Pet Food Compositions for Inducing a Satiety Response - The invention relates to pet food compositions designed to induce the animal to cease feeding upon consumption of the appropriate nutritional amount. The invention further provides methods of inducing satiety response in animals and methods of controlling the amount of food intake in animals. | 10-24-2013 |
20130281533 | Pet Food Compositions and Methods for Weight Loss and Matinenance - The present invention provides food compositions and methods for companion animals that are effective in preventing or treating obesity. | 10-24-2013 |
20150023968 | COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING HYPERTHYROIDISM IN COMPANION ANIMALS - An isolated DNA molecule comprising a fragment of the gene encoding the feline NIS is disclosed as well as methods of use thereof. Also provided are methods for rational diet design of food composition suitable for administration to feline companion animals afflicted with hyperthyroidism, comprising (a) accessing at least one database that comprises a first data set relating functional gene profile of a biofluid or tissue sample from an animal to physiological condition of the animal, where the functional gene profile is that of the feline NIS gene; (b) accessing at least one database that comprises a second data set relating effects of bioactive dietary components on the functional gene profile; (c) using an algorithm drawing on these data sets, processing input data defining physiological condition to derive a nutritional formula promoting wellness of a feline companion animal afflicted with hyperthyroidism; and (d) preparing a food composition based on the nutritional formula. | 01-22-2015 |