Shames
Alexander Shames, Beer-Sheva IL
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20140266202 | Magnetic resonance apparatus for fast and reliable detection and recognition of minute quantities of specific substances - Detection and recognition of taggant substances having predefined zero external field magnetic resonance signatures. An object comprising taggant substance(s) is irradiated with a sequence of specific excitation pulses of electromagnetic radiation within a predetermined time and frequency scanning pattern, responsive nuclear spin echo signals are received from the object with a predetermined time and frequency acquisition pattern and data indicative thereof is generated. The scanning and acquisition patterns used permit successive transmission of pulses of multiple frequencies using a two-pulse spin-echo excitation technique, or a steady state-spin echo excitation technique, and successive acquisition of multiple nuclear spin echo response signals, within a time slot between two successive excitation pulses of a specific excitation frequency. The generated data is correlated with reference data corresponding to predetermined taggant substance(s) and one or more taggant substances are identified based on the determined correlation. | 09-18-2014 |
20150018638 | APPARATUS AND METHOD FOR NON-INVASIVE MEASUREMENT OF BLOOD PARAMETERS - The present invention provides techniques for non-invasive measurement of blood related parameters based on NMR (nuclei) relaxation techniques carried out using a relatively low constant magnetic field in the range of 0.15 to 0.5 Tesla. A plurality of electromagnetic excitation pulse sequences having relatively low radiofrequencies are applied over a living tissue placed in the magnetic field and blood related parameters of the examined subject are determined using a plurality of nuclear spin echo signals received from the tissue in response to the applied excitation sequences, thereby allowing to improve the accuracy of the obtained signals and substantially reducing the time duration of the process. | 01-15-2015 |
Benjamin Shames, Arlington, MA US
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20120129155 | METHODS FOR AMPLIFYING HEPATITIS C VIRUS NUCLEIC ACIDS - A method of amplifying an HCV nucleic acid in an HCV infected sample comprises amplifying a segment of a DNA template that is complementary to a genome of HCV RNA from the sample by a two-stage PCR, wherein a first stage PCR employs a first outer primer and a second outer primer, and a second stage PCR employs a first inner primer and a second inner primer. The nucleotide sequence of the first outer primer comprises a nucleotide sequence as set forth in SEQ ID NO: 2; or SEQ ID NO:9, wherein optionally 1, 2 or 3 nucleotides are other nucleotides than those of SEQ ID NO: 9. The nucleotide sequence of the second outer primer comprises a nucleotide sequence set forth in SEQ ID NO: 3 or 4; or a nucleotide sequence as set forth in SEQ ID NO: 10 or 11, wherein optionally 1, 2 or 3 nucleotides are other nucleotides than those of SEQ ID NO: 10 and 11. The nucleotide sequence of the first inner primer comprises a nucleotide sequence as set forth in SEQ ID NO: 5; or SEQ ID NO:12, wherein optionally 1, 2 or 3 nucleotides are other nucleotides than those of SEQ ID NO: 12. The nucleotide sequence of the second inner primer comprises a nucleotide sequence as set forth in SEQ ID NO: 6 or 7; or a nucleotide sequence as set forth in SEQ ID NO: 13 or 14, wherein optionally 1, 2 or 3 nucleotides are other nucleotides than those of SEQ ID NO: 13 and 14. | 05-24-2012 |
20140199684 | METHODS FOR AMPLIFYING HEPATITIS C VIRUS NUCLEIC ACIDS - A method of amplifying an HCV nucleic acid in an HCV infected sample comprises amplifying a segment of a DNA template that is complementary to a genome of HCV RNA from the sample by a two-stage PCR, wherein a first stage PCR employs a first outer primer and a second outer primer, and a second stage PCR employs a first inner primer and a second inner primer. The nucleotide sequence of the first outer primer comprises a nucleotide sequence as set forth in SEQ ID NO: 2; or SEQ ID NO:9, wherein optionally 1, 2 or 3 nucleotides are other nucleotides than those of SEQ ID NO: 9. The nucleotide sequence of the second outer primer comprises a nucleotide sequence set forth in SEQ ID NO: 3 or 4; or a nucleotide sequence as set forth in SEQ ID NO: 10 or 11, wherein optionally 1, 2 or 3 nucleotides are other nucleotides than those of SEQ ID NO: 10 and 11. The nucleotide sequence of the first inner primer comprises a nucleotide sequence as set forth in SEQ ID NO: 5; or SEQ ID NO:12, wherein optionally 1, 2 or 3 nucleotides are other nucleotides than those of SEQ ID NO: 12. The nucleotide sequence of the second inner primer comprises a nucleotide sequence as set forth in SEQ ID NO: 6 or 7; or a nucleotide sequence as set forth in SEQ ID NO: 13 or 14, wherein optionally 1, 2 or 3 nucleotides are other nucleotides than those of SEQ ID NO: 13 and 14. | 07-17-2014 |
David Shames, San Francisco, CA US
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20130084286 | DIAGNOSTIC MARKERS - The present invention provides methods of predicting response to a cancer therapy based on the methylation status of the ERBB2 gene. One aspect of the invention provides a method of predicting response to an EGFR inhibitor therapy based on the methylation status of the ERBB2 gene. | 04-04-2013 |
20130084287 | DIAGNOSTIC MARKERS - The present invention provides methods for determining epithelial and mesenchymal phenotype of tumors and predicting whether tumor growth will be sensitive or resistant to treatment with an EGFR inhibitor. | 04-04-2013 |
20130259867 | DIAGNOSIS AND TREATMENTS RELATING TO HER3 INHIBITORS - The present application describes the use of NRG1 overexpression as a selection criterion for treating cancer patients with a HER3 inhibitor, such as a bispecific HER3/EGFR inhibitor, and methods of treating those patients. | 10-03-2013 |
20150086543 | DIAGNOTIC MARKERS - The present invention provides methods of predicting response to a cancer therapy based on the methylation status of the ERBB2 gene. One aspect of the invention provides a method of predicting response to an EGFR inhibitor therapy based on the methylation status of the ERBB2 gene. | 03-26-2015 |
Howard Morris Shames, Pennfield, NY US
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20080288346 | Method for Private Sellers to Certify Previously Owned Vehicles - A method is taught whereby an individual vehicle seller who wishes to sell his or her vehicle privately (without using a dealer) can provide a potential purchaser with a certification of the vehicle that is backed by a known and reputable vehicle maintenance-and-repair entity. A method of advertising the certification online is also provided as an optional marketing outlet to the vehicle seller. | 11-20-2008 |
Lisa Shames, Palos Verdes, CA US
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20140108301 | MARKETING DEVICE AND USEFUL OBJECT HOLDER FOR USE IN AN AUTOMOBILE - A marketing device that also functions as a useful object holder in an automobile is described herein. The marketing device can be placed on or attached to a prominent viewing position in the vehicle within easy reaching distance. The device can be placed on or attached securely so that the device will remain substantially in place during movement of the automobile. The device can have one or more dedicated areas for holding a useful object and marketing means. The dedicated areas can allow for free removal or placement of the useful device and marketing means. The useful object can draw the attention of an individual, causing repeated exposure to the marketing means and increasing the effectiveness of the marketing means. | 04-17-2014 |
Lisa Shames, Thousand Oaks, CA US
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20150182054 | MULTIPURPOSE SERVING TRAY - Serving trays configured to securely hold both stemware and/or non-stemware articles, such as glasses, are disclosed herein. The trays can comprise securing portions, which in turn can comprise channel and receptacle portions allowing for easy and secure holding of stemware by the tray. The tray can further comprise features for securing non-stemware articles and in some embodiments, can comprise features for securing both stemware and non-stemware articles. The trays can further comprise various features to improve the stability and handling of the tray. | 07-02-2015 |
Samuel Shames, Newton, MA US
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20150101788 | METHODS AND APPARATUSES FOR MANIPULATING TEMPERATURE - Methods and apparatuses for manipulating the temperature of a surface are provided. Devices of the present disclosure may include a thermal adjustment apparatus, such as a controller in electrical communication with one or more thermoelectric materials, placed adjacent to the surface of skin. The device may generate a series of thermal pulses at the surface, for providing an enhanced thermal sensation for a user. The thermal pulses may be characterized by temperature reversibility, where each pulse includes an initial temperature adjustment, followed by a return temperature adjustment, over a short period of time (e.g., less than 120 seconds). The average rate of temperature change upon initiation and upon return may be between about 0.1° C./sec and about 10.0° C./sec. In some cases, the average rate of the initial temperature adjustment is greater in magnitude than the average rate of the return temperature adjustment. | 04-16-2015 |