Patent application number | Description | Published |
20090011036 | Drug containing hollow protein nanoparticles of particle-forming protein, fused with disease-treating target-cell-substance - The subject invention provides a disease-treating drug that uses hollow protein nanoparticles to specifically act on a target cell or tissue. The present invention allows a protein drug to be effectively capsulated in the particles. The invention also provides a therapeutic method using such a drug. The drug according to the present invention is capable of recognizing a specific cell, such as hepatocytes, and manufactured by fusing a disease-treating substance for a target cell (for example, interferon, hepatocyte growth factor etc.) with hollow nanoparticles of a particle-forming protein (for example, hepatitis B virus surface-antigen protein). | 01-08-2009 |
20090053311 | Pharmaceutical Compositions for Treating or Preventing Bone Conditions - Provided herein is a pharmaceutical composition for treating, preventing or ameliorating a bone or cartilage condition and methods of making and using the same. | 02-26-2009 |
20100137218 | Expression System of NELL Peptide - Recombinant NELL peptides and methods of preparing the same are disclosed. | 06-03-2010 |
20100249376 | NELL Peptide Expression Systems and Bone Formation Activity of NELL Peptide - The invention generally relates to a bone growth factor, and more particularly to compositions including NELL1, articles of manufacture including NELL1 and methods of using NELL1 to induce bone formation. This invention also provides methods for the expression and purification of NELL1 and NELL2 peptides. | 09-30-2010 |
20100292445 | Method for Efficient Purification of Bionanocapsule - The present invention provides a method for purifying a heat-resistant bio-nanocapsule composed mainly of a protein produced by using a eukaryotic cell. The method comprises heat-treating a lysate of the eukaryotic cell to remove contaminant proteins, and then subjecting the resulting product to chromatography. | 11-18-2010 |
20110263017 | TECHNIQUE FOR REGULATING REGENRATION OF TISSUE OR FAULTY OR ABNORMAL PART IN ORGAN USING NELL-1 - The object aims to form and maintain a cell, a tissue or an organ induced by differentiation. Disclosed is a composition for inducing the differentiation of a cell capable of being differentiated in a given direction to thereby produce a cell, a tissue or an organ through the further induction of the differentiation in the given direction. The composition comprises NELL-1 or a substance which can be altered so as to act as NELL-1 upon the differentiation. Also disclosed is a composition for maintaining a cell, a tissue or an organ produced by the induction of the differentiation. | 10-27-2011 |
20110300184 | PHARMACEUTICAL COMPOSITIONS FOR TREATING OR PREVENTING BONE CONDITIONS - Provided herein is a pharmaceutical composition for treating, preventing or ameliorating a bone or cartilage condition and methods of making and using the same. | 12-08-2011 |
20120077742 | Expression System Of NELL Peptide - Recombinant NELL peptides and methods of preparing the same are disclosed. | 03-29-2012 |
20150044663 | TECHNIQUE FOR REGULATING REGENERATION OF TISSUE OR FAULTY OR ABNORMAL PART IN ORGAN USING NELL-1 - The object aims to form and maintain a cell, a tissue or an organ induced by differentiation. Disclosed is a composition for inducing the differentiation of a cell capable of being differentiated in a given direction to thereby produce a cell, a tissue or an organ through the further induction of the differentiation in the given direction. The composition comprises NELL-1 or a substance which can be altered so as to act as NELL-1 upon the differentiation. Also disclosed is a composition for maintaining a cell, a tissue or an organ produced by the induction of the differentiation. | 02-12-2015 |