Silke
John Silke, Victoria AU
Patent application number | Description | Published |
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20110008802 | TNFalpha GENE EXPRESSION AS A BIOMARKER OF SENSITIVITY TO ANTAGONISTS OF INHIBITOR OF APOPTOSIS PROTEINS - TNFα gene expression can be used as a biomarker of a cell's sensitivity to antagonists of inhibitor of apoptosis proteins (IAPs). Methods of the invention are useful for screening patients to identify those who could benefit from administration of an IAP antagonist to treat various malignant or benign tumors, benign proliferative diseases, or autoimmune diseases. | 01-13-2011 |
20140303090 | Smac Mimetic Therapy - A Smac mimetic therapy wherein the Smac mimetic is selected and developed based at least in part on its poor inhibition of XIAP-dependent processes. | 10-09-2014 |
John Silke, Melbourne AU
Patent application number | Description | Published |
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20130273036 | Fn14 Binding Proteins and Uses Thereof - The present disclosure provides proteins comprising antibody antigen binding domains that bind to Fn14 and uses thereof. The present disclosure also provides methods for treating wasting disorders, such as cachexia. | 10-17-2013 |
Neil Silke, Williamstown AU
Patent application number | Description | Published |
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20140131431 | MAIL BOX - A receptacle for receiving and securely storing mail includes a body defining an opening through which mail is received and a storage area into which mail is stored. A door is pivotably mounted within the opening and configured to close the opening in a closed position and to pivot away from the body to facilitate access to the opening in an opened position. A ramp is mounted within the body and configured to receive and direct mail into the storage area. A closing member is pivotably mounted within the body and linked to the door, such that movement of the door from the closed position to the opened position causes the closing member to pivot towards the ramp to substantially prevent access to the storage area from the opening when the door is in an open position. | 05-15-2014 |