Ter Haar
Ernst Ter Haar, Roslindale, MA US
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20080262205 | Inhibitors of GSK-3 and crystal structures of GSK-3beta protein and protein complexes - The present invention relates to inhibitors of GSK-3 and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors and methods of utilizing those compositions in the treatment and prevention of various disorders, such as diabetes and Alzheimer's disease. In addition, the invention relates to molecules or molecular complexes which comprise binding pockets of GSK-3β or its homologues. The invention relates to a computer comprising a data storage medium encoded with the structure coordinates of such binding pockets. The invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. The invention relates to methods of using the structure coordinates to screen for and design compounds that bind to GSK-3β protein or homologues thereof. The invention also relates to crystallizable compositions and crystals comprising GSK-3β protein or GSK-3β protein complexes. | 10-23-2008 |
20100227814 | INHIBITORS OF GSK-3 AND CRYSTAL STRUCTURES OF GSK-3BETA PROTEIN AND PROTEIN COMPLEXES - The present invention relates to inhibitors of GSK-3 and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors and methods of utilizing those compositions in the treatment and prevention of various disorders, such as diabetes and Alzheimer's disease. In addition, the invention relates to molecules or molecular complexes which comprise binding pockets of GSK-3β or its homologues. The invention relates to a computer comprising a data storage medium encoded with the structure coordinates of such binding pockets. The invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. The invention relates to methods of using the structure coordinates to screen for and design compounds that bind to GSK-3β protein or homologues thereof. The invention also relates to crystallizable compositions and crystals comprising GSK-3β protein or GSK-3β protein complexes. | 09-09-2010 |
20110129896 | INHIBITORS OF GSK-3 AND CRYSTAL STRUCTURES OF GSK-3Beta PROTEIN AND PROTEIN COMPLEXES - The present invention relates to inhibitors of GSK-3 and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors and methods of utilizing those compositions in the treatment and prevention of various disorders, such as diabetes and Alzheimer's disease. In addition, the invention relates to molecules or molecular complexes which comprise binding pockets of GSK-3β or its homologues. The invention relates to a computer comprising a data storage medium encoded with the structure coordinates of such binding pockets. The invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. The invention relates to methods of using the structure coordinates to screen for and design compounds that bind to GSK-3β protein or homologues thereof. The invention also relates to crystallizable compositions and crystals comprising GSK-3β protein or GSK-3β protein complexes. | 06-02-2011 |
Gail Ter Haar, Oxford GB
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20120271169 | ULTRASOUND SYSTEMS - A sensing system for sensing the condition of an object comprises a transducer arranged to generate pressure waves directed at the object and detection means, such as a pressure wave detector, arranged to detect cavitation or other processes in the object. The system further comprises processing means arranged to receive detection signals from the detection means, to process the detection signals to measure a signal parameter of the detection signals that varies with a parameter of the object, and may generate a sensor output that varies in response to changes in the signal parameter. | 10-25-2012 |
Mark Barend Ter Haar, Bristol GB
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20130004387 | A Carrier Holder - A carrier holder that prevents contamination of a carrier before, during or after performing a test using the carrier is disclosed. The carrier holder includes an elongated member having a first end and a second end. The elongated member is substantially hollow and is configured to open radially outward at the second end. Further, the carrier holder includes one or more carriers within the elongated member. For performing a test using a carrier, one or more of a gaseous or a fluid sample is allowed to enter the elongated member through the second end. Thereafter, the carrier is dispensed directly into a receptacle when the receptacle is inserted into the second end. | 01-03-2013 |
Max Robert Anthony Ter Haar, Rijswijk NL
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20100319533 | CYCLONIC FLUID SEPARATOR - A cyclonic fluid separator has a tubular housing ( | 12-23-2010 |
20120285546 | TAPERED THROTTLING VALVE - The invention relates to a throttling valve comprising a fluid inlet ( | 11-15-2012 |
20120297742 | CYCLONIC FLUID SEPARATOR - A cyclonic fluid separator has a tubular housing ( | 11-29-2012 |
Philip G. Ter Haar, Brampton CA
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20110184983 | METHOD AND SYSTEM FOR EXTRACTING AND CHARACTERIZING RELATIONSHIPS BETWEEN ENTITIES MENTIONED IN DOCUMENTS - Methods and devices for use in gathering and analyzing data from a corpus of documents. A corpus of documents is initially scanned for words that qualify as entities according to user defined criteria. Multiple counters track the number of documents which mention specific entities. A database of entities mentioned in the documents is maintained and an entry for each entity in the corpus is placed in the entity database. The results are then presented to a user in a spiral form with the most important entity at the center of the spiral. The importance of an entity may be determined by either how many entities it is connected to or how many documents mention that entity. A connection exists between two entities if they are both mentioned in at least one document and the more documents mention two specific entities at the same time, the stronger the connection between those two specific entities. The result presentation to the user is capable of also visually representing connections between entities by connecting connected entities with lines. The strength of a connection can also be represented with the width of the line connecting two entities. | 07-28-2011 |
Robbert H. Ter Haar, Lebanon, OH US
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20130295227 | Composition Comprising a Sensitive Ingredient - A composition having from 45% to 90%, by weight, of a first portion and from 10% to 55%, by weight, a second portion. The first portion has a lower melting point than the second portion. The first portion can have a higher water activity than the second portion. The first portion contains a sensitive ingredient which can be a Probiotic. The composition can be a supplement intended to be given to a pet. | 11-07-2013 |
20140030382 | Bacteriophage Treated Food Products - Food treated with bacteriophage, as to reduce or prevent the growth of undesirable bacteria. The food may be coated with bacteriophage and rubbed to distribute the phage on the food surface. The food may be coated in two or more layers. A process for treating food with bacteriophage comprises contacting the food with the bacteriophage and rubbing the coated food surface. The coating and/or rubbing may be performed in vibratory conveyor. | 01-30-2014 |
20140348986 | Avocado Processing - Avocados are processed in a controlled manner to optimize and maintain their levels of mannoheptulose and perseitol. The avocado flesh is used as a source of these materials in food compositions, especially pet foods. | 11-27-2014 |
20140349002 | Ingestible Compositions Containing Criollo Avocado Component - The undomesticated, i.e., criollo-type of avocado found growing in the tropics, particularly in the Dominican Republic, is used to prepare nutritional compositions for oral ingestion by humans and lower animals, especially pets such as dogs and cats. | 11-27-2014 |
20150132420 | PROCESSES FOR PREPARING A CARBOHYDRATE EXTRACT COMPRISING MANNOHEPTULOSE AND COMPOSITIONS COMPRISING SAME - Disclosed herein is a process for preparing a carbohydrate extract comprising mannoheptulose from avocados, as well as compositions, including food compositions, comprising such extracts. The process includes separating the aqueous emulsion into different fractions by centrifugation, and isolating the water-soluble fraction (water extract) comprising avocado carbohydrates, including mannoheptulose. In various aspects, the process optionally includes steps of heating, ultrafiltration, nanofiltration, concentrating, and or drying the extract. Also described herein are methods for using the carbohydrate extract comprising mannoheptulose and compositions comprising the carbohydrate extract comprising mannoheptulose. | 05-14-2015 |
Robbert H. Ter Haar, Dayton, OH US
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20100203225 | Supplement, Process for Making, and Packaging - A pet food composition comprising a supplement. The supplement can include a glucose mimetic component. The supplement can include a glucose mimetic component that is a glucose anti-metabolite. The glucose anti-metabolite can be 2-deoxy-D-glucose, 5-thio-D-glucose, 3-O-methylglucose, anhydrosugars including 1,5-anhydro-D-glucitol, 2,5-anhydro-D-glucitol, 2,5-anhydro-D-mannitol, mannoheptulose, and/or avocado extract comprising mannoheptulose. | 08-12-2010 |
Robert H. Ter Haar, Dayton, OH US
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20100003368 | PROBIOTIC SUPPLEMENT, PROCESS FOR MAKING, AND PACKAGING - A pet food composition comprising a supplement is provided. The supplement can comprise a Probiotic component, a cocoa butter component, and a sweetener component. A process for making the supplement can comprise providing a sweetener component, a cocoa butter component, and a Probiotic component, mixing the cocoa butter component and Probiotic component to form a mixture in a temperature and humidity controlled chamber; mixing the mixture with the sweetener component in the temperature and humidity controlled chamber to form a final mixture; optionally mixing in a colorant with the final mixture; and cooling the final mixture. A package for the supplement can comprise a secondary container housing a primary container, which houses a supplement. An array of packages is also provided. | 01-07-2010 |
20100003369 | PROBIOTIC SUPPLEMENT, PROCESS FOR MAKING, AND PACKAGING - A pet food composition comprising a supplement is provided. The supplement can comprise a Probiotic component, a cocoa butter component, and a sweetener component. A process for making the supplement can comprise providing a sweetener component, a cocoa butter component, and a Probiotic component, mixing the cocoa butter component and Probiotic component to form a mixture in a temperature and humidity controlled chamber; mixing the mixture with the sweetener component in the temperature and humidity controlled chamber to form a final mixture; optionally mixing in a colorant with the final mixture; and cooling the final mixture. A package for the supplement can comprise a secondary container housing a primary container, which houses a supplement. An array of packages is also provided. | 01-07-2010 |
Thomas J.m. Ter Haar, Hengelo NL
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20140138036 | TENSIONED VENETIAN BLIND SYSTEM - The invention relates to a tensioned Venetian blind system comprising a head rail ( | 05-22-2014 |
Thomas Johan Maria Ter Haar, Hengelo NL
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20150300085 | Device for mounting a shaft of a screen on a surface - The present invention relates to a device for mounting a shaft of a screen, such as a window covering, on a surface such as a wall, window frame or a ceiling, wherein the device comprises a mounting bracket and a shaft holder, wherein the mounting bracket is configured for mounting on the surface and the shaft holder is attachable to the mounting bracket, wherein the shaft holder is provided with coupling means for coupling the shaft and the shaft holder in releasably attachable manner to the mounting bracket. | 10-22-2015 |