Patent application number | Description | Published |
20120018334 | CONJUGATED ANTIMICROBIAL AGENTS - Provided herein are antimicrobial conjugates of two antibiotic agents, exhibiting improved activity also against resistant bacteria, compared to each of the agents separately or their mixture, and having substantially no resistance emerged thereagainst, as well as processes for preparation the same, compositions containing the same, and uses thereof in medical treatments against pathogenic microorganisms. The disclosed antimicrobial conjugates are composed of aminoglycosides and non-ribosomal active antibiotics. Some of the antimicrobial conjugates are prepared via “click” chemistry. | 01-26-2012 |
20130237489 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS - A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5″ position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I: | 09-12-2013 |
20140357590 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS - A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5″ position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I: | 12-04-2014 |
20140357591 | CONJUGATED ANTIMICROBIAL AGENTS - Provided herein are antimicrobial conjugates of two antibiotic agents, exhibiting improved activity also against resistant bacteria, compared to each of the agents separately or their mixture, and having substantially no resistance emerged thereagainst, as well as processes for preparation the same, compositions containing the same, and uses thereof in medical treatments against pathogenic microorganisms. The disclosed antimicrobial conjugates are composed of aminoglycosides and non-ribosomal active antibiotics. Some of the antimicrobial conjugates are prepared via “click” chemistry. | 12-04-2014 |
Patent application number | Description | Published |
20110173362 | HARDWARE VIRTUALIZATION FOR MEDIA PROCESSING - Methods and systems for implementing virtual processors are disclosed. For example, in an embodiment a processing apparatus configured to act as a plurality of virtual processors includes a first virtual program space that includes a first program execution memory, the first program execution memory including code to run a non-real-time operating system capable of supporting a one or more non-real-time applications, a second virtual program space that includes a second program execution memory, the second program execution memory including code to run one or more real-time processes, and a central processing unit (CPU) configured to operate in a first operating mode and a second operating mode, the CPU being configured to perform operating system and application activities using the first virtual program space for the first operating mode without using the second virtual program space and without appreciably interfering with the one or more real-time processes that are running in the second operating mode. | 07-14-2011 |
20130128885 | DATA PATH ACCELERATION USING HW VIRTUALIZATION - A processing core includes a packet classifier, implemented in a single processing core, configured to classify incoming data packets into first data packets of a known data packet flow and into second data packets of an unknown data packet flow, a first path thread, implemented in the single processing core, configured to process ones of the first data packets at least by forwarding the first data packets to a destination that corresponds to a previously determined destination associated with the known data packet flow, and a second path thread, implemented in the single processing core, configured to process a received second data packet at least to determine a new data packet flow for the second data packet. | 05-23-2013 |
20140169372 | Network Discovery Apparatus - A network device has a packet input unit, a checking unit, and a discovery unit. The packet input unit is configured to receive ingress packets. The checking unit is configured to determine whether identifying characteristics of received ingress packets match stored identifying characteristics of a packet flow that is stored in a memory, to perform a network action when the identifying characteristic of the received ingress packet matches the stored identifying characteristic. The discovery unit is configured to intercept an egress packet received from the control plane processor, the egress packet corresponding to the received ingress packet, to determine one or more differences in selected portions of a header portion of the received ingress packet resulting from processing at the control plane processor, and to store in the memory a new network action based on the one or more differences. | 06-19-2014 |
20140334321 | HEURISTIC NETWORK TRAFFIC CLASSIFICATION USING BYTE-DISTRIBUTIONS - A network device has counters that are configured to generate for a plurality of byte positions in a specified portion of data packets, a count indicative of a correspondence of a value found at the byte position corresponding to a rule such that occurrences of predetermined byte values in the plurality of byte positions may be counted. A packet classifier is configured to receive from the counters a number of byte values corresponding to the rules and to classify data packets based on the analysis. | 11-13-2014 |
20150074310 | HARDWARE VIRTUALIZATION FOR MEDIA PROCESSING - Methods and systems for implementing virtual processors are disclosed. For example, in an embodiment a processing apparatus configured to act as a plurality of virtual processors includes a first virtual program space that includes a first program execution memory, the first program execution memory including code to run a non-real-time operating system capable of supporting a one or more non-real-time applications, a second virtual program space that includes a second program execution memory, the second program execution memory including code to run one or more real-time processes, and a central processing unit (CPU) configured to operate in a first operating mode and a second operating mode, the CPU being configured to perform operating system and application activities using the first virtual program space for the first operating mode without using the second virtual program space and without appreciably interfering with the one or more real-time processes that are running in the second operating mode. | 03-12-2015 |