Timothy H.
Timothy H. Bayburt, Champaign, IL US
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20150065363 | BIOMIMETIC CHEMICAL SENSORS USING NANOELECTRONIC READOUT OF OLFACTORY RECEPTORS - The present invention provides biomimetic sensor devices that utilize proteins—such as G-protein coupled receptors—and are useful in high-sensitivity analysis of analyte-containing samples. These sensors may be used to determine the presence or concentration of one or more analytes in a sample. The invention also includes methods of fabricating the devices and methods of using the devices to assay samples. | 03-05-2015 |
Timothy H. Bayburt, Urbana, IL US
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20090257950 | Membrane Scaffold Proteins - The membrane scaffold proteins (MSP) of the present invention assemble with hydrophobic or partially hydrophobic proteins to form soluble nanoscale particles which preserve native structure and function; they are improved over liposomes and detergent micelles, both in terms of stability and preservation of biological activity and native conformation. In the presence of phospholipid, MSPs form nanoscopic phospholipid bilayer disks, with the MSP stabilizing the particle at the perimeter of the bilayer domain. The particle bilayer structure allows manipulation of incorporated proteins in solution or on solid supports, including for use with such surface-sensitive techniques as scanning probe microscopy or surface plasmon resonance. The nanoscale particles, which are robust in terms of integrity and maintenance of biological activity of incorporated proteins, facilitate pharmaceutical and biological research, structure/function correlations, structure determinations, bioseparations, and drug discovery. | 10-15-2009 |
Timothy H. Bestor, New York, NY US
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20110177508 | UNIVERSAL METHYLATION PROFILING METHODS - This invention provides methods of derivatizing a double-stranded DNA comprising contacting double-stranded DNA with a CpG methyltransferase and an s-adenosylmethionine analog. This invention also provides methods of sequencing DNA to determine methylation patterns. This invention also provides neobases and methods of sequencing for methylation patterns using neobases. | 07-21-2011 |
Timothy H. Claman, Andover, MA US
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20130086198 | APPLICATION-GUIDED BANDWIDTH-MANAGED CACHING - Methods and systems for populating a cache memory that services a media composition system. Caching priorities are based on a state of the media composition system, such as media currently within a media composition timeline, a composition playback location, media playback history, and temporal location within clips that are included in the composition. Caching may also be informed by descriptive metadata and media search results within a media composition client or a within a media asset management system accessed by the client. Additional caching priorities may be based on a project workflow phase or a client project schedule. Media may be partially written to or read from cache in order to meet media request deadlines. Caches may be local to a media composition system or remote, and may be fixed or portable. | 04-04-2013 |
20130275312 | METHODS AND SYSTEMS FOR COLLABORATIVE MEDIA CREATION - A collaboration server hosts software for collaborative composition and editing of a media project with project collaborators using different media editing applications each having their own native data format. Project collaborators, such as video editors, sound editors, effects and graphics artists, and producers access a shared project workspace which contains a snapshot of the current state of the media project in a canonical format, as well as source media files, native application metadata, and change notes. Each editing application includes a module enabling it to read the canonical snapshot representation, and also to flatten its native data model representation into the canonical representation for writing to the shared project workspace. A collaboration server hosts the shared project space, and includes a workflow manager for issuing change notifications and handling versions, and an application server for the shared project user interface. Change notes are generated manually and also expressed automatically in terms of machine-readable change primitives that serve to direct an editor's attention to portions of the media project needing attention. | 10-17-2013 |
20140289472 | APPLICATION-GUIDED BANDWIDTH-MANAGED CACHING - Methods and systems for populating a cache memory that services a media composition system. Caching priorities are based on a state of the media composition system, such as media currently within a media composition timeline, a composition playback location, media playback history, and temporal location within clips that are included in the composition. Caching may also be informed by descriptive metadata and media search results within a media composition client or a within a media asset management system accessed by the client. Additional caching priorities may be based on a project workflow phase or a client project schedule. Media may be partially written to or read from cache in order to meet media request deadlines. Caches may be local to a media composition system or remote, and may be fixed or portable. | 09-25-2014 |
Timothy H. Daubenspeck, Essex Junction, VT US
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20110012249 | IC CHIP PACKAGE HAVING IC CHIP WITH OVERHANG AND/OR BGA BLOCKING UNDERFILL MATERIAL FLOW AND RELATED METHODS - An IC chip package, in one embodiment, may include an IC chip including an upper surface including an overhang extending beyond a sidewall of the IC chip, and underfill material about the sidewall and under the overhang. The overhang prevents underfill material from extending over an upper surface of the IC chip. In another embodiment, a ball grid array (BGA) is first mounted to landing pads on a lower of two joined IC chip packages. Since the BGA is formed on the lower IC chip package first, the BGA acts as a dam for the underfill material thereon. The underfill material extends about the respective IC chip and surrounds a bottom portion of a plurality of solder elements of the BGA and at least a portion of respective landing pads thereof. | 01-20-2011 |
20110193218 | Solder Interconnect with Non-Wettable Sidewall Pillars and Methods of Manufacture - A solder interconnect structure is provided with non-wettable sidewalls and methods of manufacturing the same. The method includes forming a nickel or nickel alloy pillar on an underlying surface. The method further includes modifying the sidewall of the nickel or nickel alloy pillar to prevent solder wetting on the sidewall. | 08-11-2011 |
20140077367 | SOLDER INTERCONNECT WITH NON-WETTABLE SIDEWALL PILLARS AND METHODS OF MANUFACTURE - A solder interconnect structure is provided with non-wettable sidewalls and methods of manufacturing the same. The method includes forming a nickel or nickel alloy pillar on an underlying surface. The method further includes modifying the sidewall of the nickel or nickel alloy pillar to prevent solder wetting on the sidewall. | 03-20-2014 |
Timothy H. Gilfedder, Felixstowe GB
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20100046754 | QUANTUM COMMUNICATION METHOD AND SYSTEM BETWEEN TWO USERS USING TWO PAIRS OF PHOTONS EMMITED BY AN INDEPENDENT LASER SOURCE - The present invention relates to the exchange of information, in particular using quantum mechanically entangled particles. Information is exchanged between a first party and a second party, by: (i) generating a third party group of entangled particles; (ii) quantum mechanically entangling the particles from the third party group with a first particle, which first particle is in a state that contains information to be conveyed from the first party apparatus; (iii) quantum mechanically entangling the particles from the third party group with a second particle, which second particle is in a state that contains information to be conveyed from the second party apparatus; (iv) using the first party apparatus to perform a local measurement on at least one of the third party group of entangled particles such that the result of the measurement provides an indication of the information from the second party apparatus; and, (v) using the second party apparatus to perform a local measurement on at least a further one of the third party group of entangled particles such that the result of the measurement provides an indication of the information from the first party apparatus. | 02-25-2010 |
Timothy H. Gilfedder, Ipswich GB
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20100003030 | OPTIMISATION OF PASSIVE OPTICAL NETWORKS - The present invention relates to communications network design, and in particular the use of passive optical networks (PONs) for optimising an existing large network infrastructure such as a backhaul network. The present invention provides a computer implemented method of designing a PON based network, the method comprising: receiving data representing a plurality of network nodes having cable interconnection routes; determining a combination of core nodes from the network nodes, the core nodes being selected by allocating a combined cost to a series of core node combinations and selecting the lowest combined cost core node combination, the combined cost of each core node combination comprising a cost allocated for each of a number of core node selection criteria; allocating a number of network nodes to each core node in the selected core node combination; for each core node in the selected core node combination, determining a combination of PONS having respective cable interconnection routes for servicing the respective allocated nodes from the core node, the PONS being selected by allocating a combined cost to a series of PON combinations and selecting the lowest combined cost PON combination, the combined cost of each PON combination comprising a cost allocated to each PON within the respective combination for each of a number of PON selection criteria; and outputting data representing each of the lowest cost PON combinations. | 01-07-2010 |
Timothy H. Keho, Dhahran SA
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20110096626 | Machine, Program Product and Method to Determine a First Arrival of a Seismic Trace - Embodiments of a machine, program product and computer implemented method to perform a process of picking an initial first arrival from at least one trace of the plurality of seismic traces and a process of refining the initial first arrival pick based upon a comparison of the initial first arrival pick with first arrival pick of adjacent traces is disclosed. Such embodiments perform the steps of: centering a main time window around each of the plurality of possible first arrivals for the seismic traces, setting a start of the time window to zero, transforming the plurality traces into a plurality of peak spike traces; dividing the main window into a plurality of sub-windows; comparing each of the plurality of peak spikes in the sub-window, determining the first arrivals, and determining if the first arrival is a desired pick. | 04-28-2011 |
20120293179 | Apparatus and Method for Multi-Component Wellbore Electric Field Measurements Using Capacitive Sensors - A method and apparatus is provided for collecting reservoir data. The method includes providing one or more electromagnetic sources for generating an electromagnetic field in a reservoir and providing one or more electromagnetic sensors equipped with capacitive electrodes. The electromagnetic source is located separately from the electromagnetic sensor. The electromagnetic sensor may either be located within a well or at the surface, is capable of measuring the electromagnetic field in three dimensions, and may be isolated from the well fluids. The data collected by the electromagnetic sensors can be used to create a model of the oil reservoir, including the water saturation. | 11-22-2012 |
Timothy H. Linberg, West Roxbury, MA US
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20120322380 | LOCALIZED TRACKING OF ITEMS WITH ELECTRONIC LABELS - In one aspect, the present disclosure describes a method that may include identifying, by a monitoring device, a transmission signal of an electronic label, where the monitoring device includes an antenna and a processor. The method may include determining a distance for monitoring the transmission signal of the electronic label, and calibrating a transmission strength for communication with the electronic label via the transmission signal, where the transmission strength is calibrated to approximately achieve the distance. The method may include configuring a communication link between the antenna and the electronic label at approximately the transmission strength, monitoring availability of the communication link, identifying a loss of connection with the communication link, and responsive to the loss of connection, causing, by the monitoring device, an alert to be issued. | 12-20-2012 |
Timothy H. Sanchez, Somerville, MA US
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20150125136 | Vaporization & Inhalation System with Convective and Conductive Heaters for Herbal Material and/or Fluid Extracts - Disclosed is an appliance for volatilizing active substances in either herbal material or fluid extract for inhalation, including a material vaporization surface with a plurality of convective air flow apertures, a conductive heater and a convective heater. | 05-07-2015 |
Timothy H. Suh, Cedar Rapids, IA US
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20140328721 | METHODS OF MAINTAINING AND USING A HIGH CONCENTRATION OF DISSOLVED COPPER ON THE SURFACE OF A USEFUL ARTICLE - A method for maintaining and using a high concentration of dissolved copper on a surface of a useful article by providing a copper surface without coatings thereon which increase the wetting angle and which isolate the copper surface and which has a surface roughness between 2 and 50 micro inches Ra, so as to kill microbes thereon. | 11-06-2014 |
20140329110 | METHODS OF MAINTAINING AND USING A HIGH CONCENTRATION OF DISSOLVED COPPER ON THE SURFACE OF A USEFUL ARTICLE - A method for maintaining and using a high concentration of dissolved copper on a surface of a useful article by providing a copper surface without coatings thereon which increase the wetting angle and which isolate the copper surface and which has a surface roughness between 2 and 50 micro inches Ra, so as to kill microbes thereon. | 11-06-2014 |
20140329111 | METHODS OF MAINTAINING AND USING A HIGH CONCENTRATION OF DISSOLVED COPPER ON THE SURFACE OF A USEFUL ARTICLE - A method for maintaining and using a high concentration of dissolved copper on a surface of a useful article by providing a copper surface without coatings thereon which increase the wetting angle and which isolate the copper surface and which has a surface roughness between 2 and 50 micro inches Ra, so as to kill microbes thereon. | 11-06-2014 |
Timothy H. Williams, Campbell, CA US
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20130274659 | DEVICE, SYSTEM AND METHODS FOR THE ORAL DELIVERY OF THERAPEUTIC COMPOUNDS - Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade within the wall to release the drug to produce a therapeutic effect. The preparation can be coupled to a delivery mechanism having one or more balloons or other expandable devices which are expandable responsive to a condition in the small intestine or other GI lumen to advance the preparation out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. | 10-17-2013 |
20140221927 | DEVICE, SYSTEM AND METHODS FOR THE ORAL DELIVERY OF THERAPEUTIC COMPOUNDS - Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade within the wall to release the drug to produce a therapeutic effect. The preparation can be coupled to a delivery mechanism having one or more balloons or other expandable devices which are expandable responsive to a condition in the small intestine or other GI lumen to advance the preparation out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. | 08-07-2014 |