Patent application number | Description | Published |
20090043330 | Embolic protection devices and methods - The present invention provides a PreStent comprising a sheath and frame designed for preparing a vessel passageway for the subsequent delivery of a stent. The PreStent can be self-expanding or balloon-expandable. Also provided is a supporting system for delivering the PreStent safely. The supporting system includes a delivery catheter, one or more occlusion balloon, optionally one or more dilation balloon, and a retention sheath for the self-expanding type of PreStent. The PreStent of the present invention is flexible for use with a variety of stent and guidewire models such that it can easily be incorporated with existing devices to improve stenting procedures. | 02-12-2009 |
20090112239 | Sticky dilatation balloon and methods of using - The present invention involves an expandable element with an outer sticky surface. The expandable element may be in the form of a balloon with deflated and inflated configurations. The expandable element serves to both dilate a lumen in a blood vessel thereby opening it and to exert force upon the sticky surface in order to press it into apposition against a vessel wall. The outer sticky surface may be provided directly upon the expandable element or on a separate outer sheath that conforms to and follows the contours of the expandable element. The sticky surface may take the form of a biochemical composition and/or a mechanically abrasive structure such as microhooks, hairs, mesh netting, etc. Optionally, additional expandable elements may be provided proximal and distal to the main element to occlude blood flow on either side of a lesion in order to better trap emboli for collection. | 04-30-2009 |
20100119578 | EXTRACELLULAR MATRIX MODULATING COATINGS FOR MEDICAL DEVICES - A unique method and coatings are provided to promote/allow early stage tissue encapsulation/endothelization of medical devices while effectively controlling excessive tissue buildup by eluting antiproliferative therapeutic agent within a body of a patient. The method involves using a therapeutic agent that suppresses excessive extracellular matrix proliferation and allows/promotes thin tissue healing/encapsulation/endothelization of the device. Optimized timing of onset of elution to match onset of excessive extracellular matrix proliferation for maximum effectiveness is achieved by delay barrier with biochemical switch. | 05-13-2010 |
20110086081 | COATING SYSTEM AND METHOD FOR DRUG ELUTION MANAGEMENT - The teachings are directed to a medical device having a drug-retaining coating that at least substantially delays the initial elution of a drug for a time effective at forming a functional endothelium over a surface of the medical device. | 04-14-2011 |
20140287134 | Coating system and method for drug elution management - The teachings are directed to a medical device having a drug-retaining coating that at least substantially delays the initial elution of a drug for a time effective at forming a functional endothelium over a surface of the medical device. | 09-25-2014 |
Patent application number | Description | Published |
20120209323 | APPARATUS AND METHODS FOR SEALING A VASCULAR PUNCTURE - A sealant is provided for sealing a puncture through tissue that includes an elongate first section including a proximal end, a distal end, and a cross-section sized for delivery into a puncture through tissue, and a second section fused to and extending from the distal end of the first section. The first section may be formed from a freeze-dried hydrogel that expands when exposed to physiological fluid within a puncture. The second section may be formed from a solid mass of non-freeze-dried, non-crosslinked hydrogel precursors, the precursors remaining in an unreactive state until exposed to an aqueous physiological, whereupon the precursors undergo in-situ crosslinking with one another to provide an adhesive layer bonded to the first section. Apparatus and methods for delivering the sealant into a puncture through tissue are also provided. | 08-16-2012 |
20120290001 | APPARATUS AND METHODS FOR SEALING A VASCULAR PUNCTURE - An apparatus for sealing a puncture through tissue having an introducer sheath therein includes an elongate positioning member including a housing on a proximal end and an expandable member on a distal end, and a cartridge advanceable along the positioning member from a proximal position to a distal position. The cartridge includes a tubular member including a sealant and an advancer member disposed within lumen of the tubular member. A sleeve is slidably disposed over the tubular member distal end such that, when the tubular member is advanced over the positioning member, the tubular member distal end enters the introducer sheath while the sleeve is stopped and slides over the tubular member to expose the tubular member distal end within the introducer sheath. The introducer sheath and cartridge are then withdrawn, exposing the sealant within the puncture. | 11-15-2012 |
20130046376 | METHOD AND DEVICES FOR FLOW OCCLUSION DURING DEVICE EXCHANGES - A method of reducing the risk of clinical sequelae to catheter induced vascular injuries may include introducing a guide wire into a vascular sheath residing in a blood vessel, proximally retracting the vascular sheath while leaving the wire in place, and observing indicia of the presence or absence of a vascular injury caused to the blood vessel by the vascular sheath or a procedural catheter previously advanced through the vascular sheath. If indicia of a vascular injury are observed, the method may further involve proximally retracting the guide wire to position the inflatable balloon adjacent the injury and inflating the balloon to reduce blood flow past the injury, while leaving the guide wire in place to provide subsequent access to the injury. | 02-21-2013 |
20130060318 | METHOD AND DEVICES FOR FLOW OCCLUSION DURING DEVICE EXCHANGES - A method for facilitating treatment of catheter induced vascular injuries may first involve introducing a guide wire into a vascular sheath residing in a blood vessel, where the guide wire has a distal end and an inflatable balloon at least 15 cm proximal of the distal end. The method may further involve proximally retracting the vascular sheath while leaving the wire in place and observing indicia of the presence or absence of a vascular injury caused to the blood vessel by the vascular sheath or a procedural catheter previously advanced through the vascular sheath. If indicia of a vascular injury are observed, the method may involve positioning the inflatable balloon at or near the vascular injury and inflating the balloon to reduce blood flow past the vascular injury, while leaving the guide wire in place to provide subsequent access to the injury. | 03-07-2013 |
20130226229 | APPARATUS AND METHODS FOR SEALING A VASCULAR PUNCTURE - A sealant is provided for sealing a puncture through tissue that includes an elongate first section including a proximal end, a distal end, and a cross-section sized for delivery into a puncture through tissue, and a second section fused to and extending from the distal end of the first section. The first section may be formed from a freeze-dried hydrogel that expands when exposed to physiological fluid within a puncture. The second section may be formed from a solid mass of non-freeze-dried, non-crosslinked hydrogel precursors, the precursors remaining in an unreactive state until exposed to an aqueous physiological, whereupon the precursors undergo in-situ crosslinking with one another to provide an adhesive layer bonded to the first section. Apparatus and methods for delivering the sealant into a puncture through tissue are also provided. | 08-29-2013 |
20130304107 | METHOD AND DEVICES FOR FLOW OCCLUSION DURING DEVICE EXCHANGES - Methods and devices for maintaining vascular access and/or minimizing bleeding during percutaneous interventions. The method can include advancing an access wire through a previously placed access catheter in a contralateral femoral artery to position an inflatable balloon on the access wire in a vascular access sheath located in an ipsilateral femoral artery, without using any additional guidewires to advance the access wire. After withdrawing the vascular access sheath at least partway out of the ipsilateral femoral artery to expose the vascular injury, the balloon can be inflated to occlude the ipsilateral femoral artery or an ipsilateral iliofemoral artery at or near the vascular injury; | 11-14-2013 |
20140100646 | METHOD AND DEVICES FOR FLOW OCCLUSION DURING DEVICE EXCHANGES - A method of treating an injured blood vessel of a patient may first involve inflating a balloon of an access wire balloon catheter within the injured blood vessel to reduce blood flow past an injury site in the vessel. After inflation, the method may involve attaching an extension wire to an extra-corporeal end of the access wire balloon catheter that resides outside the patient. When the extension wire is attached, an inflation port of the access wire device is disposed outside the patient and between a free end of the extension wire and the balloon of the access wire balloon catheter. The method may further include advancing at least a first treatment catheter into the blood vessel over the access wire balloon catheter and at least a portion of the extension wire and treating the injured blood vessel using the first treatment catheter. | 04-10-2014 |
Patent application number | Description | Published |
20140239916 | PROTECTIVE CASE WITH SWITCH COVER - A protective case can house a portable electronic device. The portable electronic device can have a switch (e.g., for switching an operational mode of the portable electronic device). The protective case can have a switch cover that engages the switch of the portable electronic device when the portable electronic device is in the protective case. The switch cover can be moved between positions corresponding to positions of the switch of the portable electronic device. As the switch cover is moved, the switch cover correspondingly moves the switch. | 08-28-2014 |
20140268518 | DURABLE PROTECTIVE BATTERY CASE - A durable and water-resistant or water-proof communication accessory with a built-in battery for a mobile communication device capable of enclosing, powering, and protecting a mobile device and protecting it from dirt, water, weather, bumps, and scratches. The built-in battery can extend the life of mobile communication device while protecting the sensitive electronics, glass screen, and data. | 09-18-2014 |
20140268519 | PROTECTIVE CASE FOR MOBILE DEVICE - Disclosed is durable and water-resistant or water-proof communication accessory with a built-in battery for a mobile communication device capable of enclosing, powering, and protecting a mobile device and protecting it from dirt, water, weather, bumps, and scratches. The built-in battery can extend the battery operating time of mobile communication device while protecting the sensitive electronics, glass screen, and data. | 09-18-2014 |
Patent application number | Description | Published |
20100001962 | MULTI-TOUCH TOUCHSCREEN INCORPORATING PEN TRACKING - The present invention relates to a multi-touch display system that supports both multi-touch human input as well as input from a digital pen. The display system has a display panel that is configured to allow human touches along a front surface to be detected and tracked. The display panel also includes a location pattern that preferably covers the viewable areas of the display panel. The location pattern is configured to allow any location within the location pattern to be detected by analyzing a portion of the display pattern that is associated with the particular location. The digital pen is used to “write” on the display panel, wherein such a writing function involves detecting the location where writing occurs and controlling display content that is displayed on the display panel to reflect what is being written. | 01-07-2010 |
20100001963 | MULTI-TOUCH TOUCHSCREEN INCORPORATING PEN TRACKING - The present invention relates to a multi-touch display system that supports both multi-touch human input as well as input from a digital pen. The display system has a display panel that is configured to allow human touches along a front surface to be detected and tracked. The display panel also includes a location pattern that preferably covers the viewable areas of the display panel. The location pattern is configured to allow any location within the location pattern to be detected by analyzing a portion of the display pattern that is associated with the particular location. The digital pen is used to “write” on the display panel, wherein such a writing function involves detecting the location where writing occurs and controlling display content that is displayed on the display panel to reflect what is being written. | 01-07-2010 |
20120011450 | METHODS AND SYSTEMS FOR GENERATING AND SHARING AN INTERACTIVE VIRTUAL MEETING SPACE - Embodiments of the invention provide a computer-implemented methods and systems for interactive communication in a network. The method includes creating, by a first user of a first device, an electronic greeting card comprising at least one interactive object. The electronic greeting card provides a virtual meeting space for a plurality of users. Further, the method includes sending, by the first user, the electronic greeting card to one or more of the plurality of users. The one or more of the plurality of users modify the electronic greeting card. The method further includes sending, by the first user, the modified electronic greeting card to a receiver of the plurality of users. Furthermore, the method includes displaying, at a receiving device of the receiver, the modified electronic greeting card. The plurality of the first users and the receiver can interactively communicate through the virtual meeting space. | 01-12-2012 |
20120192088 | METHOD AND SYSTEM FOR PHYSICAL MAPPING IN A VIRTUAL WORLD - A method and system for capturing user actions in the real world and mapping the users, their actions, and their avatars into a three dimensional virtual environment. Data representing real world users are captured, collected and sent to a virtual proxy bridge, which transforms the data into control signal for avatars, which are then mapped to the virtual environment. The real world avatars move around in parallel with the users in the real world via the use of data capture devices such as radio frequency identification (“RFID”) readers, triangulation or global positioning satellite (“GPS”) systems, and cameras. Real world users can therefore be represented as virtual users, thus removing the distinction between real world users and virtual environment users. | 07-26-2012 |
20130227433 | COLLABORATION SYSTEM - A collaboration system provides enhanced user interface to enable users to interact with electronic devices. In one embodiment, users can add content to a digital system by using a pen that streams coordinates so that input to the digital system may be based on conventional pen and paper handwriting. In another embodiment, a pie-based menu system is used for input to large display area digital devices in which an occluded portion of the pie-based menu system is not used for direct input by the user. The selection of which areas of the pie-based menu system should be omitted from use is adaptive and responsive to whether the user is left-handed or right-handed, and the wrist angle defined by the user's posture. In still another embodiment, an ergonomic open-shaped pie menu system is provided to facilitate selection of options on a digital surface. | 08-29-2013 |
Patent application number | Description | Published |
20100239554 | EXTENDED RECOMBINANT POLYPEPTIDES AND COMPOSITIONS COMPRISING SAME - The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions. | 09-23-2010 |
20110046060 | Coagulation factor IX compositions and methods of making and using same - The present invention relates to compositions comprising factor IX coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions. | 02-24-2011 |
20110046061 | Coagulation factor VII compositions and methods of making and using same - The present invention relates to compositions comprising factor VII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions. | 02-24-2011 |
20120263701 | COAGULATION FACTOR VII COMPOSITIONS AND METHODS OF MAKING AND USING SAME - The present invention relates to compositions comprising factor VII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions. | 10-18-2012 |
20120263703 | COAGULATION FACTOR IX COMPOSITIONS AND METHODS OF MAKING AND USING SAME - The present invention relates to compositions comprising factor DC coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions. | 10-18-2012 |
20130045522 | MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES - The present invention provides random copolymers containing zwitterions and one or more functional agents, and methods of preparing such random copolymers. | 02-21-2013 |
20140024776 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS - The present invention provides multi-armed high MW polymers containing hydrophilic groups and one or more functional agents, and methods of preparing such polymers. | 01-23-2014 |
20140186327 | COAGULATION FACTOR IX COMPOSITIONS AND METHODS OF MAKING AND USING SAME - The present invention relates to compositions comprising factor IX coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions. | 07-03-2014 |
20140301974 | EXTENDED RECOMBINANT POLYPEPTIDES AND COMPOSITIONS COMPRISING SAME - The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions. | 10-09-2014 |
20140328819 | COAGULATION FACTOR VII COMPOSITIONS AND METHODS OF MAKING AND USING SAME - The present invention relates to compositions comprising factor VII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions. | 11-06-2014 |
20150344862 | COAGULATION FACTOR IX COMPOSITIONS AND METHODS OF MAKING AND USING SAME - The present invention relates to compositions comprising factor IX coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions. | 12-03-2015 |