Patent application number | Description | Published |
20100020163 | FLUORESCENCE ENDOSCOPE - A fluorescence endoscope is provided that can easily judge whether body-cavity tissue is benign or malignant when fluorescence generated at the entire inner circumferential face of the body cavity serving as a subject is observed. The fluorescence endoscope includes: an insertion portion ( | 01-28-2010 |
20100036262 | FLUORESCENCE ENDOSCOPE APPARATUS - The effect of noise light originating in a light guide portion is removed by simple calculations, and a clear fluorescence image that facilitates distinction between lesion tissue and normal tissue is acquired. Provided is a fluorescence endoscope apparatus including an insertion portion inserted into a body cavity; a light source unit that is disposed at a base end of the insertion portion and that emits excitation light and reference light that contains at least a part of the wavelength band of fluorescence produced by the excitation light; a light guide portion that guides the excitation light and the reference light emitted from the light source unit to a distal end of the insertion portion; an irradiation control unit that switches between a first irradiation state in which the excitation light guided by the light guide portion is radiated onto an inner wall of the body cavity and a second irradiation state in which the reference light is radiated onto the inner wall of the body cavity; an image-acquisition unit that acquires reflected light of the reference light and the fluorescence returning from the inner wall of the body cavity to the insertion portion; and an image computing unit that generates a fluorescence image signal by calculating the difference between a first image-acquisition signal acquired by the image-acquisition unit in the first irradiation state and a second image-acquisition signal acquired in the second irradiation state. | 02-11-2010 |
20100053312 | ENDOSCOPE APPARATUS - The distal end of an inserted portion, having a simple structure, is reduced in diameter, loss of light incident from a body cavity is reduced, and light from two different directions is observed simultaneously and in a separated fashion. Provided is an endoscope apparatus ( | 03-04-2010 |
20100245619 | FLUOROSCOPY APPARATUS - A fluoroscopy apparatus includes an illumination portion irradiating an observation target with illumination light; a fluorescence image acquisition device acquires fluorescence emitted from an observation target to acquire a fluorescence image; a fluorescence image-acquisition optical system forms an image of the observation target using the fluorescence; a reference-light image acquisition device acquires returning light from the observation region to acquire a reference image; a reference-light image-acquisition optical system forms an image using the returning light; and an image correction section corrects the fluorescence image by the reference image, wherein the product of an pixel density of the reference-light image acquisition device and the image-forming magnification of the reference-light image-acquisition optical system is less than the product of the pixel density of the fluorescence image acquisition device and the image-forming magnification of the fluorescence image-acquisition optical system. | 09-30-2010 |
20110121200 | FLUORESCENCE OBSERVATION APPARATUS - A quantitative fluorescence image and appropriate brightness is acquired and observed. Provided is a fluorescence observation apparatus including: an illumination section that includes a light source for irradiating an observation target region with illumination light and excitation light; a fluorescence image acquisition section that acquires a fluorescence image from fluorescence produced in the observation target region; a white-light image acquisition section that acquires a reference image from return light returning from the observation target region; an exposure-time adjustment unit that adjusts the exposure time based on the luminance value of the reference image; a diaphragm control section and a semiconductor laser control section that control the intensity of the illumination light and that of the excitation light based on the exposure time; a first normalization section that normalizes the luminance of the reference image and the fluorescence image by the exposure time; a second normalization section that normalizes the luminance of the reference image and the fluorescence image by the light intensity; and
| 05-26-2011 |
20120076434 | FLUOROSCOPY APPARATUS, FLUOROSCOPY SYSTEM, AND FLUORESCENCE-IMAGE PROCESSING METHOD - Observation is performed with a fluorescence image having high quantitativeness by satisfactorily eliminating dependency on distance. Provided is a fluoroscopy apparatus including an illumination unit having a light source that radiates illumination light and excitation light onto an observation target site, a fluorescence-imaging unit that acquires a fluorescence image by imaging fluorescence generated at the observation target site by the radiation of excitation light, a white-light-imaging unit that acquires a reference image by imaging return light returning from the observation target site by the radiation of the illumination light, and an image-correction unit that obtains a correction fluorescence image by raising the luminance value of the fluorescence image to the power of a reciprocal of a first exponent obtained by a power approximation of a distance characteristic of luminance versus observation distance, for the fluorescence image, that obtains the correction reference image by raising the luminance value of the reference image to the power of a reciprocal of a second exponent obtained by a power approximation of a distance characteristic of luminance versus observation distance, for the reference image, and that obtains a corrected fluorescence image by dividing the correction fluorescence image by the correction reference image. | 03-29-2012 |
20120197134 | Lesion Extracting Device and Lesion Extracting Method - A lesion extracting device includes a light source for emitting an excitation light toward a subject body, a control unit for changing an amount of the excitation light, a light irradiating and receiving portion for irradiating the excitation light to the subject body and receiving fluorescence generated from the subject body, a distance holding member for holding a distance between the subject body and the light irradiating and receiving portion at a predetermined value, a measuring unit for measuring the intensity of the fluorescence received by the light irradiating and receiving portion, and an extracting unit for extracting a lesion part of the subject body based on relationships between measured values of changes in the fluorescence intensity with respect to changes in the amount of the excitation light and information regarding the changes in the amount of the excitation light, the information being obtained from the control unit. | 08-02-2012 |
20120328175 | FLUOROSCOPY APPARATUS - A fluoroscopy apparatus includes a light-source device that generates illumination light and excitation light; a fluorescence-image generating unit that generates a fluorescence image based on irradiation with the excitation light; a white-light-image generating unit that generates a white-light image based on irradiation with the illumination light; a fluorescence-image correcting unit that generates a corrected fluorescence image by dividing the signal strengths of pixels in the fluorescence image by the signal strengths of pixels in the white-light image; a characteristic-value acquiring unit that extracts the characteristic value of the corrected fluorescence image; a threshold setting unit that sets a threshold for determining a region of interest in the corrected fluorescence image using a history of characteristic values extracted by the characteristic-value acquiring unit; and a pseudo-color-image generating unit that discriminates between a region of interest and another region in the corrected fluorescence image on the basis of the threshold. | 12-27-2012 |
20120330165 | FLUOROSCOPY APPARATUS - A fluoroscopy apparatus is adopted which includes a fluorescence-image generating section that generates a fluorescence image of a subject, a white-light-image generating section that generates a white-light image of the subject, a fluorescence-image correcting section that generates a corrected fluorescence image in which luminance values of pixels are normalized by dividing the luminance values of the pixels of the fluorescence image by the luminance values of the pixels of the white-light image, an error-image identifying section that standardizes white-light-image acquisition conditions and identifies an error region, which is a region in which the luminance values of the corrected fluorescence image exceed a preset allowable error range, on the basis of a gray level of the normalized white-light image, and a monitor that displays the error region. | 12-27-2012 |
20130003922 | FLUOROSCOPY APPARATUS AND FLUOROSCOPY METHOD - Provided is a fluoroscopy apparatus that includes an illumination section including a light source for radiating illumination light and excitation light onto a subject; a fluoroscopic image acquisition section acquiring a fluoroscopic image of fluorescence generated in the subject; a return-light image acquisition section acquiring a reference image of return light returning from the subject; a distance-information acquisition section acquiring information about a distance between the return-light image acquisition section and the subject; and an image correction section correcting the fluoroscopic image by using the reference image. The image correction section sets a correction coefficient based on the distance information, generates a correction reference image or a correction fluoroscopic image by performing a power calculation for light intensity information of the reference image and/or the fluoroscopic image by using the correction coefficient as an index, and divides the correction fluoroscopic image by the correction reference image. | 01-03-2013 |
20130039562 | IMAGE PROCESSING DEVICE AND FLUOROSCOPY DEVICE - Employed is an image processing device including a fluorescence-image generating unit that images fluorescence generated at a subject irradiated with excitation light and generates a fluorescence image; a white-light-image generating unit that images white light returned from the subject irradiated with illumination light and generates a white-light image; a memory that converts the white-light image to a plurality of color signals constituting a color space; an image computing unit that corrects the plurality of color signals converted by the memory using at least one color signal among the plurality of the color signals and the fluorescence image; an image computing unit that generates a corrected image from the plurality of color signals corrected by the image computing unit; and an image combining unit that combines the fluorescence image generated by the fluorescence-image generating unit and the corrected image generated by the image computing unit. | 02-14-2013 |
20130113908 | IMAGE PROCESSING DEVICE AND IMAGE PROCESSING METHOD - Provided is an image processing device including an illuminating portion that irradiates a subject with illumination light and excitation light; a fluorescence image-acquisition portion that acquires a fluorescence image by capturing fluorescence generated at the subject; a return-light image-acquisition portion that acquires a return-light image by capturing return light returning from the subject; a color-image generating portion that generates a plurality of color images by adding different types of color information that constitute a color space to the acquired fluorescence image and return-light image; and an image combining portion that combines the plurality of color images that have been generated, wherein at least one of the fluorescence image and the return-light image is subjected to, by the color-image generating portion), correction processing in which exponents for distance characteristics, which are approximated to exponential functions, for the fluorescence image and the return-light image are matched with each other. | 05-09-2013 |
20130200273 | Fluoroscopy Apparatus, Fluoroscopy System, and Fluorescence-Image Processing Method - A fluoroscopy apparatus including: an illumination unit having a light source radiating illumination light and excitation light onto an observation target, a fluorescence-imaging unit acquiring a fluorescence image by imaging fluorescence generated at the observation target by the excitation light, a white-light-imaging unit acquiring a reference image by imaging light returning from the observation target by the illumination light, and an image-correction unit obtaining a correction fluorescence image by raising the luminance value of the fluorescence image to the power of a reciprocal of a first and second exponent obtained by a power approximation of a distance characteristic of luminance versus observation distance, for the fluorescence image, and that obtains a corrected fluorescence image by dividing the correction fluorescence image by the correction reference image. | 08-08-2013 |
20130200274 | Fluoroscopy Apparatus, Fluoroscopy System, and Fluorescence-Image Processing Method - A fluoroscopy apparatus including: an illumination unit having a light source radiating illumination light and excitation light onto an observation target, a fluorescence-imaging unit acquiring a fluorescence image by imaging fluorescence generated at the observation target by the excitation light, a white-light-imaging unit acquiring a reference image by imaging light returning from the observation target by the illumination light, and an image-correction unit obtaining a correction fluorescence image by raising the luminance value of the fluorescence image to the power of a reciprocal of a first and second exponent obtained by a power approximation of a distance characteristic of luminance versus observation distance, for the fluorescence image, and that obtains a corrected fluorescence image by dividing the correction fluorescence image by the correction reference image. | 08-08-2013 |
20130200275 | Fluoroscopy Apparatus, Fluoroscopy System, and Fluorescence-Image Processing Method - A fluoroscopy apparatus including: an illumination unit having a light source radiating illumination light and excitation light onto an observation target, a fluorescence-imaging unit acquiring a fluorescence image by imaging fluorescence generated at the observation target by the excitation light, a white-light-imaging unit acquiring a reference image by imaging light returning from the observation target by the illumination light, and an image-correction unit obtaining a correction fluorescence image by raising the luminance value of the fluorescence image to the power of a reciprocal of a first and second exponent obtained by a power approximation of a distance characteristic of luminance versus observation distance, for the fluorescence image, and that obtains a corrected fluorescence image by dividing the correction fluorescence image by the correction reference image. | 08-08-2013 |
20130201320 | Fluoroscopy Apparatus, Fluoroscopy System, and Fluorescence-Image Processing Method - A fluoroscopy apparatus including: an illumination unit having a light source radiating illumination light and excitation light onto an observation target, a fluorescence-imaging unit acquiring a fluorescence image by imaging fluorescence generated at the observation target by the excitation light, a white-light-imaging unit acquiring a reference image by imaging light returning from the observation target by the illumination light, and an image-correction unit obtaining a correction fluorescence image by raising the luminance value of the fluorescence image to the power of a reciprocal of a first and second exponent obtained by a power approximation of a distance characteristic of luminance versus observation distance, for the fluorescence image, and that obtains a corrected fluorescence image by dividing the correction fluorescence image by the correction reference image. | 08-08-2013 |
20130338438 | FLUORESCENCE ENDOSCOPE APPARATUS - A fluorescence endoscope apparatus includes: a light source unit emitting light in a combination of light in plural types of wavelength bands in two types of wavelength ranges of RGB and two types of exciting light, with plural types of emitting patterns and in a time division; an image pickup unit receiving reflected light and two types of fluorescence; and an image-processing unit outputting a white light image and two types of fluorescence images. | 12-19-2013 |
20140011823 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME - The present invention provides: a compound represented by general formula (I) below, that has both angiotensin II receptor antagonism and a PPARγ activation effect and that is useful as a preventative and/or therapeutic agent for high blood pressure, cardiac disease, arteriosclerosis, type-2 diabetes, and the like; and a drug composition containing the compound. General formula (I) (in the formula: ring A represents a pyridine ring; ring B represents a tetrazole ring or an oxadiazol-5(4H)-one ring; X represents C—R | 01-09-2014 |
20140092390 | APPARATUS AND METHOD FOR OBTAINING SPECTRAL IMAGE - An apparatus for obtaining spectral image includes a variable spectral element capable of changing its spectral characteristics, a transmission wavelength setting unit for setting a wavelength of light to be transmitted by the variable spectral element, a variable spectral element control unit changing a first control of the variable spectral element and a second control of the variable spectral element for controlling spectral characteristics of the variable spectral element to each other, an image capturing unit capturing an image that is formed by light transmitted by the variable spectral element, and an image correction unit acquiring a difference image between a first image captured in the first control and a second image captured in the second control. | 04-03-2014 |
20140213871 | FLUORESCENCE OBSERVATION APPARATUS - Provided is a fluorescence observation apparatus including a light source; a section generating a fluorescence image of an object; a section generating a reference image of the object; a section generating a corrected image in which emphasized are pixels of the reference image corresponding to pixels each having luminance value equal to or more than a first threshold value in the fluorescence image; a display unit displaying the reference image or the corrected image; a bleeding state determining section determining whether or not a bleeding region of the subject detected based on the reference image is more than a predetermined range; and a section switching between displaying the reference image on the display unit if the determining section determines that the region is not more than the range, and displaying the corrected on the image display if the determining section determines that the region is more than the range. | 07-31-2014 |
20150066417 | TEST SYSTEM - A server stores multiple configuration data. A tester hardware is configured to be capable of changing at least a part of its functions according to configuration data stored in rewritable nonvolatile memory, to supply a power supply voltage to a DUT, to transmit a signal to the DUT, and to receive a signal from the DUT. An information technology equipment is configured such that, (i) when the test system is set up, the information technology equipment acquires the configuration data from the server according to the user's input, and writes the configuration data to the nonvolatile memory. Furthermore, the information technology equipment is configured such that, (ii) when the DUT is tested, the information technology equipment executes a test program so as to control the tester hardware, and to process data acquired by the tester hardware. | 03-05-2015 |