Patent application number | Description | Published |
20110319641 | TREPROSTINIL PRODUCTION - The present invention is directed to a novel method for preparing a synthetic intermediate for treprostinil via a stereoselective alkyne addition reaction. Also described are methods of preparing treprostinil comprising the alkyne addition reaction described herein as well as novel intermediates useful for synthesis prostacyclin derivatives, such as treprostinil. | 12-29-2011 |
20120190888 | TREPROSTINIL PRODUCTION - The present invention is directed to a novel method for preparing a synthetic intermediates for treprostinil. Also described are methods of preparing treprostinil comprising utilizing novel intermediates described herein as well as novel intermediates useful for synthesis prostacyclin derivatives, such as treprostinil. | 07-26-2012 |
20120197041 | TREPROSTINIL PRODUCTION - The present invention is directed to a novel method for preparing a synthetic intermediates for treprostinil. Also described are methods of preparing treprostinil comprising utilizing novel intermediates described herein as well as novel intermediates useful for synthesis prostacyclin derivatives, such as treprostinil. | 08-02-2012 |
20120226076 | SYNTHESIS OF INTERMEDIATE FOR TREPROSTINIL PRODUCTION - The compound according to Formula I is an intermediate in the synthesis of prostacylin analogs. The present invention provides an efficient method for synthesizing a Formula I compound. | 09-06-2012 |
20120323025 | METHOD OF PRODUCING BERAPROST - An improved method is described for making single isomers of synthetic benzoprostacyclin analogue compounds, in particular the pharmacologically active 314-d isomer of beraprost. In contrast to the prior art, the method is stereoselective and requires fewer steps than the known methods for making these compounds. | 12-20-2012 |
20130345471 | SYNTHESIS OF INTERMEDIATE FOR TREPROSTINIL PRODUCTION - The compound according to Formula I is an intermediate in the synthesis of prostacylin analogs. The present invention provides an efficient method for synthesizing a Formula I compound. | 12-26-2013 |
20140275573 | METHOD OF PRODUCING BERAPROST - An improved method is described for making single isomers of synthetic benzoprostacyclin analogue compounds, in particular the pharmacologically active 314-d isomer of beraprost. In contrast to the prior art, the method is stereoselective and requires fewer steps than the known methods for making these compounds. | 09-18-2014 |
20140275616 | SALTS OF TREPROSTINIL - Provided are novel treprostinil salts as well as methods for making treprostinil salts. | 09-18-2014 |