Patent application number | Description | Published |
20120260608 | DRAIN CONNECTOR FOR SUBSTANCE PROCESSING RECEPTACLE - A drain connector arranged for mounting to a tank or bag having an interior volume includes a drain flange defining a bore having an inner diameter, and a hollow body having at least an upper portion with a maximum outer diameter that is no greater than the inner diameter of the bore and arranged to convey fluid to the interior volume, with at least one circumferential sealing element between the drain flange and hollow body, with the drain flange including a body extending outside the interior volume and including at least one retaining element arranged to retain the hollow body in a position. A drain flange may include multiple bores for receiving multiple hollow bodies, with each hollow body including at least one circumferential sealing element. One or more drain flanges may be generic for use with hollow bodies of different characteristics to enable fabrication of a processing container or bag by affixing one or more drain flanges, and then selecting among the plurality of different hollow bodies for insertion into the drain flange(s). | 10-18-2012 |
20120284991 | CONFIGURABLE PORT FITMENT, KIT, AND RELATED METHODS - A configurable port fitment includes an adapter for forming a locking engagement with a connector associated with a vessel. A kit and related methods may use the configurable port fitment. | 11-15-2012 |
20130026167 | CONTAINER SEALING SYSTEM - A cap for a container (e.g., container fitment) includes a neck portion and a lip portion that extends laterally outward from the neck portion. A gasket is provided between the cap and a rim of a container fitment. The neck portion is conical or frustoconical in shape, and an interior surface of a container port or fitment may be correspondingly tapered, to guide the cap into concentric alignment with the gasket and rim during insertion of the neck portion of the cap into the fitment. Such alignment promotes positive sealing engagement between the cap, gasket, and fitment. In one embodiment, the cap defines an externally accessible recess that optionally includes a handle, such as at least one segmenting wall, for grasping by a user to facilitate manipulation of the cap. The cap may be affixed to a fitment of a flexible liner. | 01-31-2013 |
20130167960 | DRAIN CONNECTOR FOR FLUID PROCESSING AND STORAGE CONTAINERS - A selectively closeable drain connector includes a hollow body or plunger moveable relative to a bore-defining drain flange. A locking element may be arranged to maintain the hollow body relative to the drain flange in one or more desired positions. At least one sealed jacket may extend between exterior portions of the drain flange and the hollow body to provide a barrier arranged to inhibit passage of contaminants to sealing surfaces along which the hollow body travels relative to the drain flange. The drain connector may be joined to a container, such as a tank, bag, vessel, or other receptacle for material storage and/or processing. | 07-04-2013 |
20140131380 | LINER-BASED SHIPPING AND DISPENSING CONTAINERS - In one aspect, the present disclosure relates to the substantially sterile transport of a substantially sterile substance using a liner-based assembly having an overpack and a flexible or semi-rigid liner disposed within the overpack configured for pressure dispense, and a connector securable to at least one of the overpack or liner. The connector may include a first port operably connected with a quick connector configured for substantially aseptic filling of the liner. The first port may be configured for substantially aseptic sealing after filling of the liner. The connector may be configured for substantially aseptic dispense of the substance of the liner via the first port after unsealing of the first port or via a second port. In some particular embodiments, the second port may be operably connected with a quick connector, and dispense of the substance of the liner occurs via the quick connector of the second port. The assembly may include one or more of a mixer, a sparger, a sensor, or combinations thereof, and may be arranged to form a bioreactor. Related methods are also described. | 05-15-2014 |
20140230929 | FLUID PROCESSING CONTROL SYSTEM AND RELATED METHODS - In one aspect, a system for use in processing a fluid comprises a reservoir for holding the fluid and one or more bioreactors for receiving the fluid from the reservoir. One or more sensors are provided for sensing one or more parameters of the fluid, and corresponding control measures may be initiated. Regulators may also be provided for regulating various parameters of the fluid processing operation. Related systems and methods are also disclosed. | 08-21-2014 |
20140370588 | FILTRATION APPARATUS FOR CONTINUOUS PERFUSION - In one aspect, an apparatus for bioprocessing using a liquid comprises an at least partially flexible vessel for receiving the liquid, and a filter adapted for moving within the liquid. An agitator may also be provided for agitating the liquid, and may be connected to the mixer. The mixer may spin or may not spin about an axis of rotation. | 12-18-2014 |
20150024922 | CENTRIFUGATION SYSTEM AND RELATED METHOD - In one aspect, a disposable centrifuge includes a container including an interior compartment for receiving the liquid and solids. The container is capable of rotating to urge the solids toward the periphery of the interior compartment. A fixed extraction conduit may be provided for extracting at least a portion of the solids from adjacent the periphery of the interior compartment of the container. A motive device may also be provided for forming a non-contact coupling with the container, which may rotate and/or levitate the container. A relatively low, continuous flow rate (about 250 ml/min to about 500 ml/min) may also be utilized. Related methods are also disclosed. | 01-22-2015 |