Patent application number | Description | Published |
20090018501 | Drug Coated Balloon Catheter - The present invention relates to balloon catheters for treating a luminal system of a patient. Specifically, the invention relates to catheters having a flexible membrane positioned at a distal portion of the catheter, the flexible membrane retained in a substantially unexposed conformation prior to deployment. Preferably the flexible membrane is capable of delivering a therapeutic agent to a localized environment when deployed to an exposed conformation. | 01-15-2009 |
20090157162 | RAPID-EXCHANGE RETRACTABLE SHEATH SELF-EXPANDING DELIVERY SYSTEM WITH INCOMPRESSIBLE INNER MEMBER AND FLEXIBLE DISTAL ASSEMBLY - A delivery system for delivery of a medical device, the delivery system having an inner member having a proximal section, a distal section and a longitudinal axis therebetween, and an outer member disposed about the inner member, wherein the distal section of the inner member includes at least two wires wound about the inner member. | 06-18-2009 |
20090204068 | AGENT DELIVERY CATHETER HAVING AN INFLATION BRIDGE BETWEEN TWO AXIALLY SPACED BALLOONS - An agent delivery catheter having two or more axially spaced balloons and an inflation bridge providing fluid communication between the two balloons. The catheter generally has a proximal balloon, a distal balloon, and a tube defining an inflation bridge lumen which is located in part within the inflatable interiors of the balloons, and which extends therebetween, and which has a proximal port within the proximal balloon interior and a distal port within the distal balloon interior to thereby provide for inflation of the distal balloon by placing the distal balloon interior in fluid communication with the proximal balloon interior of the shaft. | 08-13-2009 |
20090254063 | Drug Coated Balloon Catheter - The present invention relates to balloon catheters for treating a luminal system of a patient. Specifically, the invention relates to catheters having a flexible membrane positioned at a distal portion of the catheter, the flexible membrane retained in a substantially unexposed conformation prior to deployment. Preferably the flexible membrane is capable of delivering a therapeutic agent to a localized environment when deployed to an exposed conformation. | 10-08-2009 |
20090270787 | SYSTEMS AND METHODS FOR CREATING ENLARGED MIGRATION CHANNELS FOR THERAPEUTIC AGENTS WITHIN THE ENDOTHELIUM - A system for enlarging endothelium migration channels at a treatment site in a coronary vessel wall, to enable enhanced delivery of a therapeutic agent thereto. The system includes an enlarging agent, for enlarging endothelium migration channels at a treatment site in a coronary vessel wall. It also includes a delivery system, for delivering the enlarging agent to the treatment site, so that the enlarging agent will be delivered thereby to enlarge the endothelium migration channels at the treatment site, and for delivering the therapeutic agent to the delivery site. The therapeutic agent will thereby be delivered into the enlarged migration channels at the treatment site, to treat the treatment site with the therapeutic agent. | 10-29-2009 |
20100057050 | CATHETER CONFIGURED FOR INCREMENTAL ROTATION - A catheter which allows the rotational orientation of the distal end of the catheter to be adjusted in discrete intervals as the physician rotates the proximal end of the catheter. The catheter is designed to intentionally induce whipping but to limit the amount of whipping to a desired rotational interval. | 03-04-2010 |
20100145265 | AGENT DELIVERY CATHETER HAVING A RADIALLY EXPANDABLE CENTERING SUPPORT MEMBERS - A catheter for delivering an agent to an injection site in a wall of a patient's body lumen, with an elongated shaft having a needle-through lumen slidably containing a needle therein, and an expandable member on the distal shaft section which has a collapsed configuration and a radially expanded configuration. In the radially expanded configuration, the expandable member supports the shaft in a position spaced away from the body lumen wall, and the needle slidably exits the needle-through lumen in the extended configuration through the port spaced away from the body lumen wall as a portion of the expandable member maintains the position of the port section of the shaft in the body lumen. The expandable member typically has an open-walled, helical, or lobed configuration providing a perfusion path along the expandable member. | 06-10-2010 |
20100160769 | ELECTRODE DATA ANALYSIS TO INDICATE CATHETER STABILITY AND/OR NEEDLE PENETRATION SUCCESS - Determining stability of a catheter is described. A first signal originating from a first region of a patient is monitored and a second signal originating from a second region of the patient is monitored. First components from a recurring interval of the second signal are extracted, where the recurring interval is defined by the first signal. The first components are compared to determine a first similarity value of the first components over time. The first similarity value is compared to a threshold value to determine a stability evaluation for a source of the second signal. | 06-24-2010 |
20100193485 | METHODS AND SYSTEMS FOR LASER CUTTING AND PROCESSING TUBING TO MAKE MEDICAL DEVICES - Methods for making devices include providing a tubular member to be formed into a device, placing a removable sacrificial block material in the lumen of the tubular member and laser cutting the tubular member. A doping material can be added to the melted portion of the tubular member to promote the formation of brittle slag. A fixture can be used to hold a cut workpiece in order to ream sacrificial material from the surface of the workpiece. Pressurized gas can be supplied to the inner lumen of the tubular member to cause slag to form on the outside surface, rather than the inner surface, of the tubular member. A tubular member made from nickel-titanium alloy can be tightly adhered to a sacrificial sleeve utilizing the phase changes associated with nickel-titanium. A rotating mandrel can be placed within the lumen of the tubular member during laser cutting. A mandrel which includes an enlarged diameter section causes the workpiece to expand slightly within its elastic deformation range to dislodge islands from the workpiece. Such a mandrel could be formed from a tubular member which has a central lumen that can be used to deliver a pressurized medium to “blast” islands from the workpiece. | 08-05-2010 |
20100211009 | PERFUSION CATHETER HAVING ARRAY OF FUNNEL SHAPED MEMBRANES - An agent delivery catheter configured to deliver an agent to an inner surface of a patient's body lumen wall by forming an array of cells defining agent containment chambers at multiple locations along the catheter's shaft, while minimizing ischemic conditions during the procedure. | 08-19-2010 |
20100249702 | POROUS CATHETER BALLOON AND METHOD OF MAKING SAME - A porous balloon or other catheter structure is formed by creating specific size pores for delivering an agent to a body lumen. The pores can be created by passing matter or energy through the surface of the catheter structure, as by a laser or a projectile. In the case of a laser, the catheter structure can be reversed so that the inner surface becomes the outer surface to convert diverging pores into converging pores. In the case of projectiles, a pore size can be achieved by selecting an appropriate size and shaped projectile to obtain the desired characteristic. Alternatively, a material to make the catheter structure can include impurities that can be removed once the catheter structure is set, leaving pores where the material formed around the impurities. | 09-30-2010 |
20110190698 | Method and Apparatus for Delivering an Agent to a Kidney - Devices for delivering drugs or other treatment agents locally to the vasculature of a mammal are disclosed. These devices have several related structures and are designed to deliver the drugs to facilitate rapid mixing with the blood flowing past the devices. | 08-04-2011 |
20110196187 | MAGNETICALLY SENSITIVE DRUG CARRIERS AND DELIVERY DEVICES - Apparatuses for delivering compositions of matter comprising a magnetically sensitive drug carrier and a related drug and methods for causing the drug carriers to localize within the patient using an internal or external magnetic field are described. | 08-11-2011 |
20120143139 | AGENT DELIVERY CATHETER HAVING A RADIALLY EXPANDABLE CENTERING SUPPORT MEMBER - A catheter for delivering an agent to an injection site in a wall of a patient's body lumen, with an elongated shaft having a needle-through lumen slidably containing a needle therein, and an expandable member on the distal shaft section which has a collapsed configuration and a radially expanded configuration. In the radially expanded configuration, the expandable member supports the shaft in a position spaced away from the body lumen wall, and the needle slidably exits the needle-through lumen in the extended configuration through the port spaced away from the body lumen wall as a portion of the expandable member maintains the position of the port section of the shaft in the body lumen. The expandable member typically has an open-walled, helical, or lobed configuration providing a perfusion path along the expandable member. | 06-07-2012 |
20120190918 | APPARATUS AND METHODS FOR SUPPORTING CARDIAC ISCHEMIC TISSUE BY MEANS OF EMBEDDED STRUCTURES - Systems and methods are disclosed for reinforcing ischemic tissue of a heart. A reinforcing element is initially positioned within a lumen of a delivery needle. The delivery needle is urged into the ischemic tissue and the reinforcing element is urged out of the needle into the ischemic tissue. The reinforcing element may be embodied as a coiled, undulating, or arcuate spring and may include a shape-memory material. A bioabsorbable material may maintain the reinforcing element in a deformed state. The reinforcing element may be tensioned as it is positioned within the myocardium in order to provide a cinching force by means of a cord lock selectively releasing the reinforcing element. The reinforcing element may be embodied as a number of spiral portions secured to a hub and urged outwardly by rotation of the hub. | 07-26-2012 |
20130006220 | DRUG COATED BALLOON CATHETER - The present invention relates to balloon catheters for treating a luminal system of a patient. Specifically, the invention relates to catheters having a flexible membrane positioned at a distal portion of the catheter, the flexible membrane retained in a substantially unexposed conformation prior to deployment. Preferably the flexible membrane is capable of delivering a therapeutic agent to a localized environment when deployed to an exposed conformation. | 01-03-2013 |
20130092554 | ELECTROPOLISHING SOLUTION CONTAINING PHOSPHOROUS PENTOXIDE AND METHODS OF USE THEREOF - Substantially anhydrous electropolishing electrolyte solutions. The substantially anhydrous electropolishing electrolyte solutions described herein do not use water as a solvent; instead, such electropolishing electrolyte solutions use anhydrous alcohols and/or glycols as a solvent. For example, an electropolishing electrolyte solution, as described herein, may include an alcohol, at least one mineral acid, and phosphorous pentoxide (“P | 04-18-2013 |
20140121603 | AGENT DELIVERY CATHETER HAVING RADIALLY EXPANDABLE CENTERING SUPPORT MEMBER - A catheter for delivering an agent to an injection site in a wall of a patient's body lumen, with an elongated shaft having a needle-through lumen slidably containing a needle therein, and an expandable member on the distal shaft section which has a collapsed configuration and a radially expanded configuration. In the radially expanded configuration, the expandable member supports the shaft in a position spaced away from the body lumen wall, and the needle slidably exits the needle-through lumen in the extended configuration through the port spaced away from the body lumen wall as a portion of the expandable member maintains the position of the port section of the shaft in the body lumen. The expandable member typically has an open-walled, helical, or lobed configuration providing a perfusion path along the expandable member. | 05-01-2014 |
20140200655 | INTRAVASCULAR CARDIAC RESTRAINING IMPLANTS AND METHODS FOR TREATING HEART FAILURE - Intravascular cardiac restraining implants designed for treatment of heart disease and heart failure and methods for their use. The disclosed implants can be used to reshape or reinforce a diseased, weakened or distended portion of a patient's heart to counteract heart disease and heart damage. An intravascular cardiac restraining implant may include a first tissue anchor configured for implantation in a first region of a coronary vein, a second tissue anchor configured for implantation in a second region of the coronary vein, and at least one elongate member coupled to the first tissue anchor and the second tissue anchor. In one embodiment, the at least one elongate member may be a spring or a similar device configured for biasing the first and second tissue anchors toward one another, thus reshaping or reinforcing a diseased, weakened or distended portion of a patient's heart. | 07-17-2014 |
20140277392 | ELECTROPOLISHING OF ALLOYS CONTAINING PLATINUM AND OTHER PRECIOUS METALS - Radiopaque cobalt-based alloys having a smooth electropolished surface with rounded edges and methods for electropolishing such alloys. A cobalt-based alloy includes cobalt, chromium, and one or more radiopaque elements. In one embodiment, examples of radiopaque elements include so-called platinum group metals (i.e., platinum, palladium, ruthenium, rhodium, osmium, or iridium). Group 10 elements (i.e., platinum or palladium) are particularly preferred. Because of the presence of the platinum group metal(s), such alloys are generally difficult to electropolish. Electrolyte formulations and methods for electropolishing such alloys are also disclosed. | 09-18-2014 |