13th week of 2012 patent applcation highlights part 42 |
Patent application number | Title | Published |
20120077129 | PRODUCTION METHOD OF OPTICAL WAVEGUIDE FOR CONNECTOR - A production method of an optical waveguide for a connector is provided, which reduces an optical coupling loss. Cores are formed in a crossing pattern, a branched pattern or a linear pattern, and then an over-cladding layer formation photosensitive resin layer is formed over the cores. In turn, a heat treatment is performed at a temperature of 70° C. to 130° C. to properly form mixed layers in interfaces between the cores and the photosensitive resin layer. By thus forming the mixed layers, the connector optical waveguide can be produced as having a reduced optical coupling loss. | 2012-03-29 |
20120077130 | METHOD FOR GENERATING A PLURALITY OF OPTIMIZED WAVEFRONTS FOR A MULTIPLE EXPOSURE LITHOGRAPHIC PROCESS - A simplified version of a multiexpose mask optimization problem is solved in order to find a compressed space in which to search for the solution to the full problem formulation. The simplification is to reduce the full problem to an unconstrained formulation. The full problem of minimizing dark region intensity while maintaining intensity above threshold at each bright point can be converted to the unconstrained problem of minimizing average dark region intensity per unit of average intensity in the bright regions. The extrema solutions to the simplified problem can be obtained for each source. This set of extrema solutions is then assessed to determine which features are predominantly printed by which source. A minimal set of extrema solutions serves as a space of reduced dimensionality within which to maximize the primary objective under constraints. The space typically has reduced dimensionality through selection of highest quality extrema solutions. | 2012-03-29 |
20120077131 | METHOD OF FORMING PATTERN USING ACTINIC-RAY OR RADIATION-SENSITIVE RESIN COMPOSITION, AND PATTERN - According to one embodiment, a method of forming a pattern includes the step of applying an actinic-ray- or radiation-sensitive resin composition on a substrate so as to form a film, the step of selectively exposing the film through a mask and the step of developing the exposed film with the use of a developer containing an organic solvent, wherein the actinic-ray- or radiation-sensitive resin composition contains a resin (A) whose polarity is increased by the action of an acid so that the solubility of the resin in the developer containing an organic solvent is decreased, a photoacid generator (B) that when exposed to actinic rays or radiation, generates an acid containing a fluorine atom and a solvent (C), and wherein the photoacid generator (B) is contained in the composition in a ratio of 8 to 20 mass % based on the total solids of the composition. | 2012-03-29 |
20120077132 | PROCESSESS AND COMPOSITIONS FOR REMOVING SUBSTANCES FROM SUBSTRATES - Processes associated apparatus and compositions useful for removing organic substances from substrates, for example, electronic device substrates such as microelectronic wafers or flat panel displays, are provided. Processes are presented that apply a minimum volume of a composition as a coating to the inorganic substrate whereby sufficient heat is added and the organic substances are completely removed by rinsing. The compositions and processes may be suitable for removing and, in some instances, completely dissolving photoresists of the positive and negative varieties as well as thermoset polymers from electronic devices. | 2012-03-29 |
20120077133 | CANDLE FOR PROVIDING RAPID FRAGRANCE DELIVERY - A scented candle is provided which includes a dual braided wick in a candle mass. The candle mass is positioned on an inwardly sloping platform and such platform is snugly fit into a noncombustible container. A wick clip with louvers that secures and centers the wick in the candle mass allows maximum fuel flow to the wick during use to ensure full consumption of the melted candle mass. | 2012-03-29 |
20120077134 | Candle Holder with Consistent Upright Candle - A candle holder is described having a fixture with a candle, the fixture pivotally positioned in a circular gimbal that is pivotally positioned in a cylindrical housing, an enclosure that is securely fastened with a proximal end of the housing. | 2012-03-29 |
20120077135 | METHODS AND APPARATUS FOR RECYCLING GLASS PRODUCTS USING SUBMERGED COMBUSTION - A method for recycling glass mat waste, wound rovings, and other products includes providing a source of glass mat, or a plurality of rovings, for example on a roll, and routing the glass mat or rovings into a submerged combustion melter. An unwind system and a pair of powered nip rolls, powered conveyors, or other arrangement may work in combination to provide a substantially consistent rate of material into the melter. The melter may operate under less than atmospheric pressure to avoid fumes escaping the melter. A slot in the melter allows ingress of the glass mat or rovings into the melter, and a glass mat former such as a folder may be used to ensure that the mat fits through the slot. Alternatively, the glass mat may be cut by a slitter prior to entering the slot. | 2012-03-29 |
20120077136 | Method of Custom Fitting an Article of Footwear and Apparatus Including a Container - A method and apparatus for custom fitting an article of footwear is disclosed. A container holding the article of footwear includes a steaming assembly that allows a customer to subject the article of footwear to steam. The method can include cooling the article of footwear on the customer's foot to custom fit the article of footwear. | 2012-03-29 |
20120077137 | JOINING ARRANGEMENT FOR JOINING A FIRST JOINING PARTNER TO A SECOND JOINING PARTNER OF A VEHICLE - The invention relates to a joining assembly for joining partners of a vehicle, including a first joining partner, at least one second joining partner, and a holding device by which the joining partners can be connected to each other to form the joining assembly, where the holding device includes a receiving structure on which at least one adhesive member is arranged, which can be brought into at least two states, where in a first state, the adhesive member allows an adjustment of the second joining partner on the first joining partner, where the change from the first state into a second state can be activated by transformation means, where in the second state, the adhesive member is cured, whereby fixation of the joining partners to each other can be achieved. | 2012-03-29 |
20120077138 | Low Thermal Mass Semiconductor Wafer Boat - A wafer boat for a semiconductor wafer includes vertical rods, fingers supported by the vertical rods, and plates supported by the fingers. The plate has a support surface for supporting the wafer and a recessed surface spaced from the support surface and spaced from the wafer. A plurality of holes extends from the recessed surface, and the support surface is free of holes to inhibit contamination of the wafer. | 2012-03-29 |
20120077139 | Orthodontic device - An orthodontic device includes a generally U-shaped metal wire whose two ends are at different vertical heights and which therefore has a 3-dimensional recumbent S shape in front view. The U-shaped metal wire is secured, by an elastic band or a cover, to each of a plurality of orthodontic brackets cemented respectively to a patient's teeth, and due to the difference of height between the two ends of the U-shaped metal wire, a resilient restoring force is generated to individually adjust the row of teeth on the upper or lower jaw to the normal heights and thereby correct the occlusal cant and craniofacial anomalies. | 2012-03-29 |
20120077140 | PERIOSTEAL MESHER - Apparatus is provided for use with a gingival periosteum lining a bone. The apparatus comprises a periosteal mesher, which comprises a mesher surface, and a plurality of cutting elements distributed over the mesher surface, which are configured to cut the gingival periosteum to increase flexibility thereof. Other embodiments are also described. | 2012-03-29 |
20120077141 | DENTAL APPARATUS AND METHOD FOR DENTURES - A dental apparatus and method of use for producing edentulous dentures, each including a lower dental tray having a removable modular contact plate with an upwardly extending shoulder surrounding a tapered opening, a ball nut retained in the tapered opening, and a post adjustably secured to the ball nut. A modular striking plate may be removably attached to an upper dental tray or an integrated striking sector on a bottom surface of the upper dental tray is utilized to accurately obtain an established occlusal vertical and centric relation positions. The contact plate and striking plate are each configured as snap-in components to the respective trays. Additionally, the contact plate may be utilized as a spacer between the dental trays once the post and ball nut are removed. Finally, the contact plate and striking plate may be removed for functional positioning and esthetic blue printing measurements. | 2012-03-29 |
20120077142 | Dental Retraction Composition, Method of Production and Use Thereof - The invention features a composition which can or is to be used in a dental retraction, the composition comprising liquid a liquid and a layer type 1:1 silicate mineral and a layer type 2:1 silicate mineral in a ratio from about 50/50 to 5/95 wt.-% with respect to each other. The invention also relates to a container containing the dental retraction composition and to a kit comprising parts A and B, wherein part A comprises the dental retraction composition and part B comprises at least one accessory selected from the group of applier, dental impression material, retraction cap(s), a container for storing and dispensing the composition and combinations thereof. The invention further features a process of dispensing a dental retraction composition, the process comprising the steps: providing a dental retraction composition contained in a container, placing the container in an applier, and using the applier for dispensing the dental retraction composition out of the container. | 2012-03-29 |
20120077143 | ORAL CARE CLEANING AND TREATING DEVICE - A device for directing a liquid onto a plurality of surfaces of the oral cavity, the device including a handle, a neck, and a head, where the head includes a cleaning component including a chamber for maintaining the liquid proximate the surfaces, where the chamber is defined by front and rear sealing membranes, inner side walls and a base inner wall, and where the inner side walls each include a plurality of openings, the device further including a first manifold and a second manifold, a first port and a second port for conveying liquid; and means for providing an effective seal of the device within the oral cavity. | 2012-03-29 |
20120077144 | ORAL CARE CLEANING AND TREATING DEVICE - A device for directing a liquid onto a plurality of surfaces of the oral cavity, the device including a handle, a neck, and a head, where the head includes a cleaning component including a chamber for maintaining the liquid proximate the surfaces, where the chamber is defined by front and rear sealing membranes, inner side walls and a base inner wall, and where the inner side walls each include a plurality of openings, the device further including a first manifold and a second manifold, a first port and a second port for conveying liquid; and means for providing an effective seal of the device within the oral cavity. | 2012-03-29 |
20120077145 | ORAL CARE INSTRUMENT - Disclosed is an oral care instrument which can maintain a sufficient support strength of a long neck, leaves little residue of a medicant after using, has a low contamination risk from nozzle tip, allows smooth spouting of a medical solution from the beginning, prevents excessive supply of a gelatinous or creamy oral-care composition in the case of flowing the composition in a supply channel inside the same, and contributes to the maintenance of the durability of a manufacturing mold. In the aforesaid oral care instrument which comprises a handle ( | 2012-03-29 |
20120077146 | ORAL CARE INSTRUMENT INCLUDING AN ORAL CARE AGENT - An oral care instrument includes at least one oral care agent. In one embodiment, the oral care agent can be provided on one or more surfaces of the oral care instrument or included within cavities within the head or in one or more surfaces of a head. In other embodiment, the oral care agent can be provided in or on a thin slab subsequently bonded onto a surface, or applied as a stable coating. The oral care instrument can also be provided with a wear indicator. The oral care agents can be released during one use, during multiple uses, or throughout the life of the instrument. Water, oral secretions and/or chemicals within the mouth can activate the oral care agents. | 2012-03-29 |
20120077147 | Swivel Head Microimplant Wrench - The present invention relates to an instrument used to insert microimplants and more particularly, to a microimplant insertion wrench that has a head on the instrument that allows the head to swivel and rotate upon the handle. The end of the head of the instrument comprises a receptacle that receives and retains a microimplant. The head of the implant wrench can be fixed into a predetermined angulation with the aid of a set screw. Microimplants can be inserted by a counter clockwise rotation of the knurled knob on the head of the instrument, and implants can be removed by clockwise rotation of the knurled knob on the head of the implant wrench. | 2012-03-29 |
20120077148 | HAND INSTRUMENT FOR DENTAL CARE - The invention relates to a hand instrument for manual use in dental care, which comprises a substantially elongated handle ( | 2012-03-29 |
20120077149 | Dental Implant System - The invention relates to a dental implant system comprising a dental implant ( | 2012-03-29 |
20120077150 | DENTAL ABUTMENT SYSTEM - A dental implant screw for holding an abutment on a dental implant includes a head and a shaft. A proximal end of the shaft is coupled to the head. The shaft includes a threaded section, an outwardly tapered section leading into a recessed section, and a stop section directly between the outwardly tapered section and the recessed section. The recessed section is directly between the head and the stop section. The threaded section is directly adjacent a distal end of the shaft and is configured to engage threads of an internally threaded bore in the dental implant to hold the abutment on the dental implant. | 2012-03-29 |
20120077151 | Morse Taper Dental Implant - A morse taper dental implant with possibility for adaptation of components directly on the implant platform, the implant is a morse taper implant with grooves, which together with the surface treatment, promote adhesion of bone tissue to the implant, and further on the outside details, the implant has a platform switch, i.e. a notch at the top of the implant, leaving the same basis of settlement in whatever the outside diameter of the implant, thus allowing an adjustment of the components directly on the base of the implant (implant level), through the adaptation of the components through the morse taper that reaches heights exceeding 1 mm. | 2012-03-29 |
20120077152 | Cellophane cut out kits for optical art - One or more transparent or translucent sheets of cellophane are folded and cuts are made to create symmetric patterns and designs. The cellophane creates diffraction, refraction, interference, and reflection pattern of light that become strikingly visible when viewed under polarized light. The cellophane patterns and designs are placed on top of one another such that the holes in the overlapping sheets cause a variation in the path of light traveling through the layers of the cellophane, creating beautiful and varied optical patterns of light that change with the placement of the layers of cellophane and with variation of the angle of polarized light for a kaleidoscope effect. The cellophane is viewed against the backdrop of a blue sky to provide a source of polarized light. Placing the cellophane on glossy black cardboard brings out the prismatic colors created by light refraction and reflection | 2012-03-29 |
20120077153 | NUTRITION-CONTROL DEVICE - The invention provides a nutrition-control device and method for a continuous follow-up of the daily consumption during a prophylactic or therapeutic diet, enabling the active participation of a dieter in selecting the menu, and stimulating the dieter's motivation. | 2012-03-29 |
20120077154 | Incrementally-sized standard-sized eating-ware system for weight management - An incrementally-sized Standard-Sized eating-ware system and process comprise a plurality of formulas to establish and assign Standard Sizes to eating-ware. The Standard Sizes' total volumetric capacity equivalents are based on a series of incrementally-sized flat surfaces. These capacity equivalents comprise volume inside eating-ware and directly above it. Standard Sizes guide and control amount and rate of food consumed. The system and processes provide a plurality of incrementally-sized Standard-Sized eating-ware components having successively decreasing Standard Sizes appointed to be utilized in a graduated manner over a period of time and deployed during intervals to provide gradual, unnoticeable food adjustment, which enables users to modify eating habits for effective weight management while minimizing the perception of change. Numerical and letter representations of Standard Size and Calorie Density Mark guide users in selecting eating-ware components to maintain, prevent, increase or decrease weight. | 2012-03-29 |
20120077155 | Electronic Reading Device - An electronic device is provided which can be used, for example, by a user who is learning to read, to input a word in question and be provided with visual and audio output of the phonetic components of the query word, thereby assisting the learning of pronunciation of the word. The electronic device includes a plurality of word databases corresponding to different predefined classification, such as reading level, age group or reading syllabus. | 2012-03-29 |
20120077156 | DATA PROCESSING SYSTEMS APPLYING OPTICAL IDENTIFICATION DEVICES AND RELATED DATA PROCESSING AND OPERATION METHODS AND COMPUTER PROGRAM PRODUCTS THEREOF - A data processing system applying optical identification devices includes a printed matter having a plurality of encoded data printed thereon; an optical identification device for reading at least one encoded data from the printed matter; and a data processing device coupled to the optical identification device and storing a plurality of content data for reading the at least one encoded data through the optical identification device, obtaining at least one first data corresponding to an operation and one second data corresponding to one of the content data from the read encoded data and performing the corresponding operation of the first data on the one of the content data that the second data corresponds to. | 2012-03-29 |
20120077157 | METHODS AND DEVICES FOR EDUTAINMENT SPECIFICALLY DESIGNED TO ENHANCE MATH SCIENCE AND TECHNOLOGY LITERACY FOR GIRLS THROUGH GENDER-SPECIFIC DESIGN, SUBJECT INTEGRATION AND MULTIPLE LEARNING MODALITIES - Novel edutainment methods and devices designed by women for girls, based on learning and motivational psychology research, are provided. Further, the methods and devices provide a learning environment for math education that is integrated, multi-modal, and crafted to enhance the motivation, confidence, and math skills of girls in primary and secondary grades. | 2012-03-29 |
20120077158 | Predictive Performance Optimizer - A method, apparatus and program product are provided for optimizing a training regimen to achieve performance goals. Historical training data is provided. At least one training regimen is defined. A training objective is selected for at least one training regimen to optimize. The training regimen is optimized by computing an initial training regimen solution and computing a neighbor solution at a distance from the initial training regimen solution. The neighbor solution is compared to the initial training regimen solution. If the neighbor solution is determined to be a better solution than the initial training regimen solution, the initial training regimen solution is replaced with the neighbor solution. The distance is updated per a schedule to compute a next neighbor solution. | 2012-03-29 |
20120077159 | SYSTEM AND METHOD FOR COGNITIVE ASSESSMENT AND TRAINING OF AN ANIMAL - An apparatus and method for cognitive assessment and training of an animal subject. A subject is placed in a testing environment, such as a subject chamber of a cognitive assessment and training apparatus. At least one cognitive assessment and training session comprising a plurality of trials is performed. In a trial, a trial assembly is prepared at a first level. The trial assembly includes at least one stimuli and a reward, where a target stimuli of the at least one stimuli is associated with the reward. The subject is allowed access to the stimuli. When a correct response is determined from the subject, the subject is allowed to access a reward associated with the correct response. The subject is advanced to trials at a next level when a learning criterion is reached. At least one cognitive assessment score is generated based on the plurality of trials and the at least one cognitive assessment and training session. | 2012-03-29 |
20120077160 | COMPUTER-IMPLEMENTED INTERACTIVE BEHAVIORAL TRAINING TECHNIQUE FOR THE OPTIMIZATION OF ATTENTION OR REMEDIATION OF DISORDERS OF ATTENTION - The current invention provides methods of enhancing a subject's attentional state. The methods comprise a series of interactive behavioral assessments and interactive behavioral training sessions, which trains the individual to be in a more optimal attentional state throughout their day-to-day life, ultimately enhancing their cognitive performance, visuomotor performance, and emotion regulation. | 2012-03-29 |
20120077161 | Method and system for providing rule based cognitive stimulation to a user - A method and system for providing evolving, highly variable, long-term ongoing cognitive stimulation over a broad spectrum of cognitive domains. The user is presented with a series of entertaining audio/visual activities customized for the user, based on the user's life experience and cognitive level, each activity providing stimulation in one or more cognitive domains. The activities themselves and their level of challenge may change, in real time, over both the short- and the long term, varying in relation to current and historical user response patterns, creating an experience that remains engaging, with on-going use, over a period of months or years. | 2012-03-29 |
20120077162 | CONDITIONING AN ORGANISM - A system for conditioning an organism by associating a conditioned response with a conditioned stimulus, the system comprising the following. Identifying means for identifying a signal pattern associated with a conditioned response ( | 2012-03-29 |
20120077163 | 3D MONOCULAR VISUAL TRACKING THERAPY SYSTEM FOR THE REHABILITATION OF HUMAN UPPER LIMBS - It is described a 3D monocular tracking system, being robust, having low cost, easy to install and use, useful for the upper limbs rehabilitation in a patient in need thereof, as well as a home self-directed therapy method for patients having upper limbs' movement disability. The system comprising a) a handle or gripper; b) a computational vision system comprising a video camera; c) software comprising a set of games; d) a processor; and, e) a display apparatus. | 2012-03-29 |
20120077164 | Sensory Testing data analysis by categories - This invention is related to systems and methods of analyzing sensory ability data. One embodiment of the present invention includes a method comprising the steps of receiving data from a remote location. The data is comprised of sensory ability data and demographic data associated with a subject. The data may then be stored. Further, the method includes identifying a potential evaluation level associated with the subject. The evaluation level is identified, at least in part, utilizing a sports tree function. The method also includes retrieving peer data associated with the potential evaluation level. Additionally, the method includes determining when the peer data is statistically powerful for use in generating a comparative profile of the sensory ability data associated with the subject. Additional embodiments develop training programs based on one or more training program functions. | 2012-03-29 |
20120077165 | INTERACTIVE LEARNING METHOD WITH DRAWING - An interactive learning method with drawing is implemented by the execution of a program incorporated with a screen. A sequence of dots is provided on the screen. Children connect adjacent dots starting from the starting dot in sequence. A connecting line appears between a pair of adjacent dots when they are connected successively. Finally, those connecting lines constitute an object when all the pairs of adjacent dots have been connected and a series of images or an animation related to the object is displayed to strengthen children's learning impression and recognition ability. After that, a few buttons are provided on screen. When the button is touched or clicked by the children, its corresponding object is explained by text or/and voice. By doing so, it may enhance their ability of reading and listening. Hence, this interactive learning method can increase children's interest in learning. Consequently, they can learn by themselves. | 2012-03-29 |
20120077166 | PORTABLE BRUSHING STATION - A portable brushing station for encouraging good brushing habits in children includes a cabinet assembly having a countertop and a concave sink with a portable water supply and removable drainage unit. Additionally, the portable brushing station can include a removable sink and drain combination which can be easily cleaned after each use. Additionally, the portable brushing station can include an instructional and entertainment unit for interactively teaching children proper brushing habits. | 2012-03-29 |
20120077167 | Multi-Unit Interactive Dual-Video Medical Education System - The present invention is a multi-unit medical education module that includes at least two units per module. Each unit includes at least two separate videos, with one video being topical to the unit and having a length of under twenty minutes, and with the other video being a live-action interview between a health care provider and a patient (or actors representing same). The student interacts with each unit via computer and progresses to each successive unit only upon successful completion of a post-test for each unit or by individualized intervention by the supervising educator. | 2012-03-29 |
20120077168 | Display for Use in Managing Movement of a Patient in a Bed - A system is provided for communicating to health care workers the turning, positioning and schedule requirements of dependent patients with pressure ulcers, or at risk for the development of pressure ulcers. The system includes a display indicating a clock face divided into sections each with a respective window location for displaying graphics of a display element illustrating a required lying position for the patient. Each of the display elements comprises a disk mounted on the substrate for rotation about a center axis thereof at right angles to the substrate with the graphics arranged thereon at angularly spaced positions around the axis so as to rotate a selected one of the graphics to the window to be displayed. | 2012-03-29 |
20120077169 | TRACHEAL INTUBATION TRAINING MODEL AND METHOD FOR MANUFACTURING TRACHEAL INTUBATION TRAINING MODEL - Disclosed is a method for manufacturing a tracheal intubation training model with which training for securing airway by inserting an airway control device into the pharyngoesophagus can be effectively carried out. In a method for manufacturing a tracheal intubation training model for airway control training being carried out using an airway control device, an airway pharyngoesophageal area portion simulating a human airway pharyngoesophageal area which includes a pharyngoesophagus being formed in the tracheal intubation training model, the method includes: a first step where at least the pharyngoesophagus is inflated by applying an inflating pressure to the airway pharyngoesophageal area of a human body subject; a second step where the airway pharyngoesophageal area including the inflated pharyngoesophagus is imaged using an X-ray CT apparatus thus obtaining the three dimensional structure of the airway pharyngoesophageal area; and a third step where the airway pharyngoesophageal area portion is manufactured using the imaged three dimensional structure of the airway pharyngoesophageal area. | 2012-03-29 |
20120077170 | Apparatus for Demonstrating the Beneficial Effects of Elastic Arteries - An apparatus for demonstrating the beneficial effects of elastic arteries comprising an input port connected to a one-way valve, the input port having an input cross sectional area; an expandable member having an input and an output, the input of the expandable member communicatively coupled with the input port and the one-way valve for allowing fluid to flow into the expandable member, and the expandable member capable of varying in volume based on a pressure exerted at the input port; and an output port communicatively coupled with the expandable member at the output for allowing fluid to flow out of the expandable member, the output port having an output cross sectional area that is smaller then the input port cross sectional area; and a method of demonstrating the beneficial effects of elastic arteries comprising providing an arterial elasticity simulator and analogizing concepts of cardiovascular physiology with the arterial elastic simulator. | 2012-03-29 |
20120077171 | VISUAL FEEDBACK IN ELECTRONIC ENTERTAINMENT SYSTEM - The presentation of visual feedback in an electronic entertainment system is disclosed. One disclosed embodiment relates to a method of providing user feedback in an electronic entertainment system, wherein the method comprises inviting an input from a user, receiving a user input via a hand-held remote input device, performing a comparison of the user input received to an expected input, assigning a rating to the user input received based upon the comparison to the expected input, and adjusting light emitted by one or more lights sources on the input device based upon the rating. | 2012-03-29 |
20120077172 | PRESENTATION SYSTEM - A digital camera ( | 2012-03-29 |
20120077173 | SYSTEM FOR PERFORMING ASSESSMENT WITHOUT TESTING - A system for educational assessment without testing is provided that includes one or more client systems that are connected to a network allowing students or school officials to communicate with an education framework that performs and manages educational assessment. The one or more client systems issue a message to the education framework requesting a task to be performed. The educational assessment is administered independent of one or more educators so as to avoid interruption of instruction time. A server system receives the message and the education framework proceeds to process the contents of the message. The education framework includes a plurality of programming modules being executed on the server system that provides to educators specific information used for the educational assessment based on the contents of the message. The programming modules assist in calculating and determining one or more parameters for the educational assessment of the students as well as providing specific reports to educators as to the progress of the students. | 2012-03-29 |
20120077174 | COMPETENCY ASSESSMENT TOOL - Core competencies of a participant, such as an employee, is assessed using a competency assessment tool. A developer defines core competencies for any of a variety of topics and develops questions and demonstrative tasks for respective learning objectives under the core competencies. Participants, in turn, perform the demonstrative tasks that are evaluated by an observer and provide responds to the questions. A score is calculated based on the evaluation and response to determine how well the participant exhibits the learning objectives and the competency of the participant is assessed, which is communicated to the participant. A recommendation is made to an administrator to create a development plan when the participant's score falls below a predetermined threshold. In certain embodiments, the participant is a subject matter expert that validates a nexus between the learning objectives and the questions and demonstrative tasks. | 2012-03-29 |
20120077175 | TIME-INDEXED DISCUSSION ENABLED VIDEO EDUCATION - A computer-implemented system and method for presenting video with time-indexed discussion comprising program instructions stored in memory. The program instructions are executable by a computer processor to store a video on a video server, and store at least one discussion on a database, each discussion being associated with a video time index. The video is streamed from the video server to a user device. At least one discussion is transmitted for display on the user's device when the video time is within a pre-specified range of the video time index for the discussion to be displayed. | 2012-03-29 |
20120077176 | Maintaining a Secure Computing Device in a Test Taking Environment - The presently disclosed invention provides for the security of a computing device in the context of a test taking environment. By securing a computing device, an individual (or group of individuals) may more effectively proctor a large examination without worrying about a test taker illicitly accessing information on their computer or via a remote source of data. Securing a computing device includes locking out or preventing access to any application not deemed necessary or appropriate by the test administrator. | 2012-03-29 |
20120077177 | Secure Online Testing - A system for secure, web-based, proctored examinations is provided. A web-based platform allows for test delivery beyond a local testing center with the test delivered directly to the test-taker. Computing devices that have been secured for the taking of an examination allow a student or prospective professional to access an examination wherever there is an Internet connection. As a result, students and professionals can take examinations where they live, learn, and work thereby reducing the costs associated with travelling to testing centers and minimizing time away from work. Test-takers, proctors, instructors, administrators, authors, and test developers can all access data and test information anytime and anywhere. Secure examinations can be taken under the purview of a proctor either in person or via the Internet and utilizing any number of testing environment capture devices in conjunction with data forensic technologies. | 2012-03-29 |
20120077178 | SYSTEM AND METHOD FOR DOMAIN ADAPTATION IN QUESTION ANSWERING - The present disclosure relates generally to question answering systems and methods and, particularly, to systems and methods for domain adaptation in question answering. | 2012-03-29 |
20120077179 | SYSTEM AND METHOD FOR AIDING CONCEPTUAL ORGANIZATION BY CHILDREN - A system and method for assisting children in organizing and categorizing information, includes a program that includes a dual graphical and non-graphical user-interface that is operable by a child to create and identify a variety of concepts, and to organize and arrange those concepts in a non-graphical hierarchy by creating spatial associations using the graphical user-interface. | 2012-03-29 |
20120077180 | METHOD AND SYSTEM FOR KNOWLEDGE REPRESENTATION AND PROCESSING USING A STRUCTURED VISUAL IDEA MAP - A method and system for knowledge representation and processing using a structured visual idea map that allows the processing of information and viewing of information in different formats and perspectives, encouraging users to enumerate and connect concepts without a tendency to begin within a particular conceptual framework, think in a systematic way and distinguish between relevant information. The present invention can be used for presenting information in a logical manner for serious information and knowledge transfer and providing feedback on thoughts/opinions. Information can be shown in different perspectives to alter amount of information. | 2012-03-29 |
20120077181 | METHOD FOR THE CRYOPRESERVATION OF CELLS, ARTIFICIAL CELL CONSTRUCTS OR THREE-DIMENSIONAL COMPLEX TISSUES ASSEMBLIES - The cryopreservation of cells and tissue cultures for long term storage of cells, cell constructs or three-dimensional complex tissues assemblies is based on the use of a collagen cell carrier (CCC) having a specific composition and thickness and appropriate mechanical properties which are maintained after thawing. The collagen cell carrier provides a suitable support for the cryopreservation resulting in high survival rates after thawing and providing cells and tissue assemblies already adhered to a mechanically stable and biocompatible support. Frozen collagen carrier-cells assemblies, the frozen artificial cell constructs or three-dimensional complex tissue assemblies obtainable by the method and the use thereof after thawing are also disclosed. | 2012-03-29 |
20120077182 | ADDITIVE SOLUTION FOR BLOOD PRESERVATION - A method for the storage of red blood cells provides for mixing an additive solution with packed red blood cells to create a suspension of red blood cells. The method further provides for reducing the oxygen in the suspension of red blood cells; and storing the suspension of red blood cells under oxygen-depleted storage. | 2012-03-29 |
20120077183 | Reaction apparatus - An apparatus | 2012-03-29 |
20120077184 | ELECTROMAGNETIC MULTIPLEX ASSAY BIOSENSOR - A method is provided for determining the presence of multiple different target analytes in a liquid sample using electrophoretic separation and magnetic labels within a self-contained reaction cartridge and an external magnetic sensor for detection. Magnetic labels are bound to target analytes through specific binding elements. By electrophoretic separation, the multiple different targets can be sorted according to their specific sizes and inherent molecular charges for better detection resolution and specificity. After the separation process, the target analytes are then recognized and trapped by the detection binding elements within the reaction cartridge. A magnetic field generator provides a changeable magnetic field that causes the bounded magnetic labels and target analytes to produce a resonance disruption detectable by a magnetic sensor. The sensor can provide a digital binary value to indicate whether or not a label particle is bound and that determines the presence of target analytes. | 2012-03-29 |
20120077185 | DETECTION OF GENETIC ABNORMALITIES AND INFECTIOUS DISEASE - The present invention provides assay systems and related methods for detecting genetic abnormalities and infectious agents in maternal samples. Exemplary maternal samples for analysis using the assay systems of the invention include maternal blood, plasma or serum. | 2012-03-29 |
20120077186 | USE OF CYSTEINE-DERIVED SUPPRESSOR TRNAS FOR NON-NATIVE AMINO ACID INCORPORATION - Disclosed herein are compositions and methods for incorporating non-native amino acids into a single polypeptide. In one example, an isolated modified suppressor tRNA is disclosed that includes the following: a modified tRNA | 2012-03-29 |
20120077187 | RECOMBINANT ANTIGEN FOR DETECTION OF TOXOCARIASIS - A vector comprising a polynucleotide sequence encoding a polypeptide having an amino acid sequence of SEQ ID NO: 2 for detecting antibody against | 2012-03-29 |
20120077188 | METHODS FOR MANIPULATING LIQUID SUBSTANCES IN MULTI-CHAMBERED RECEPTACLES - A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle. | 2012-03-29 |
20120077189 | SCAFFOLD-BASED POLYMERASE ENZYME SUBSTRATES - The invention provides a novel class of scaffold-based labeled polymerase enzyme substrates. The polymerase enzyme substrates have a multivalent core or scaffold to which is attached fluorescent dye moieties and nucleoside phosphate moities. The polymerase enzyme substrates have multiple fluorescent dye moities and/or multiple nucleoside phosphate moieties. Preferred multivalent cores comprise trifunctional six membered aromatic moities. The invention also provides for sequencing methods and kits with scaffold-based labeled polymerase enzyme substrates. | 2012-03-29 |
20120077190 | SUBSTRATES, SYSTEMS AND METHODS FOR ANALYZING MATERIALS - Substrates, systems and methods for analyzing materials that include waveguide arrays disposed upon or within the substrate such that evanescent fields emanating from the waveguides illuminate materials disposed upon or proximal to the surface of the substrate, permitting analysis of such materials. The substrates, systems and methods are used in a variety of analytical operations, including, inter alia, nucleic acid analysis, including hybridization and sequencing analyses, cellular analyses and other molecular analyses. | 2012-03-29 |
20120077191 | GENOTYPING DNA - Described herein are compositions and methods useful for the detection of nucleic acid variations. Ligation within a probe or between probes is used to distinguish between probes perfectly complementary to a target and those containing a mismatch. Nucleotide fill-in/extension steps are optionally applied according to the type of assay performed. A circularization and relinearization step can be applied to create a template for further amplification and detection. In certain aspects, portions of a target sequence or its complement are not amplified. | 2012-03-29 |
20120077192 | Risk Assessment For Adverse Drug Reactions - The present invention provides a method of predicting the risk of a patient for developing adverse drug reactions, particularly SJS or TEN. It was discovered that an HLA-B allele, HLA-B* 1502, is associated with SJS/TEN that is induced by a variety of drugs. The correlation with HLA-B* 1502 is most significant for carbamazepine-induced SJS/TEN, wherein all the patients tested have the HLA-B* 1502 allele. In addition, another HLA-B allele, HLA-B*5801, is particularly associated with SJS/TEN induced by allopurinol. Milder cutaneous reactions, such as maculopapular rash, erythema multiforme (EM), urticaria, and fixed drug eruption, are particularly associated with a third allele, HLA-B *4601. For any of the alleles, genetic markers (e.g., HLA markers, microsatellite, or single nucleotide polymorphism markers) located between DRB1 and HLA-A region of the specific HLA-B haplotype can also be used for the test. | 2012-03-29 |
20120077193 | METHOD OF DISTINGUISHING GENOTYPES - The present invention relates to a method of distinguishing genotypes using PCR-PHFA including: a nucleic acid amplification step in which a mutation site-including region of a gene is amplified by a nucleic acid amplification reaction, thereby obtaining an amplification reaction solution; and a distinction step in which the amplification reaction solution obtained from the nucleic acid amplification step is mixed with a reference double-stranded nucleic acid having a specific genotype on the mutation site as well as being labeled with a labeling substance, and the mixture is subjected to a competitive strand displacement reaction, and the level of the occurrence of strand displacement is assessed so as to distinguish the identity; and the competitive strand displacement reaction is performed under a condition to suppress a polymerase extension reaction, and a genotype distinguishing kit for use in the distinct of genotypes by this method. | 2012-03-29 |
20120077194 | APPARATUS AND METHODS FOR PARALLEL PROCESSING OF MICRO-VOLUME LIQUID REACTIONS - Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers allowing the performance of multiple parallel reactions, the arrays can be used for reagent storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting. Use of the arrays facilitates optical analysis of reactions, and allows optical analysis to be conducted in real time. Included within the invention are kits comprising a microhole apparatus and a reaction component of the method(s) to be carried out in the apparatus. | 2012-03-29 |
20120077195 | Method for Detecting Variations in Nucleic Acid Sequences - The present invention relates to a method and a kit for detecting nucleic acid sequence variation using melting curve analysis, especially relates to a method and a kit for detecting nucleic acid sequence variation by melting curve analysis using self-quenched probe. Said method provides the characteristics of the self-quenched probe employed, as well as the corresponding nucleic acid amplification conditions, so that the probe can bind to the amplified target sequence, and variations of the target sequence can be detected by melting curve analysis. The present invention also encompasses a kit assembled according to the method described. | 2012-03-29 |
20120077196 | Universal method for selective amplification of mRNAs - The invention relates generally to methods for the amplification of ribonucleic acids, including for example messenger ribonucleic acids (mRNAs). In an embodiment, the invention also relates to kits for amplifying ribonucleic acids, including for example mRNAs. In another embodiment, the invention relates to kits comprising the components for performing the methods of the present invention. | 2012-03-29 |
20120077197 | SAMPLE THERMAL CYCLING - A sample processing apparatus includes a sample carrier receiving region configured to receive sample carrier carrying one or more samples for processing by the sample processing apparatus, and a thermal control system that controls a thermal cycling of the one or more samples for processing by the sample processing apparatus by selectively varying a pressure over a fluid in substantial thermal communication with the sample carrier, thereby varying a boiling point temperature of the fluid. | 2012-03-29 |
20120077198 | Compositions And Methods For Cancer Testing - Methods and compositions which provide a gene expression-based prognostic signature of cancer relapse and prediction of metastatic cancer are described, and in particular methods to predict colorectal cancer (CRC) recurrence and chemosensitivity. | 2012-03-29 |
20120077199 | IDENTIFICATION, MONITORING AND TREATMENT OF DISEASE AND CHARACTERIZATION OF BIOLOGICAL CONDITION USING GENE EXPRESSION PROFILES - A method provides an index that is indicative of the state of a subject, as to a biological condition, based on a sample from the subject. An embodiment of this method includes: deriving from the sample a profile data set, the profile data set including a plurality of members, each member being a quantitative measure of the amount of a distinct RNA or protein constituent in a panel of constituents selected so that measurement of the constituents enables evaluation of the biological condition; and in deriving the profile data set, achieving such measure for each constituent under measurement conditions that are substantially repeatable; and applying values from the profile data set to an index function that provides a mapping from an instance of a profile data set into a single-valued measure of biological condition, so as to produce an index pertinent to the biological condition of the subject. | 2012-03-29 |
20120077200 | PRIMERS FOR DIAGNOSING AVELLINO CORNEAL DYSTROPHY - The present invention relates to a real-time PCR primer pair and probe for diagnosing Avellino corneal dystrophy, and more particularly to a real-time PCR primer pair and probe for diagnosing Avellino corneal dystrophy, which can accurately diagnose the presence or absence of a mutation in exon 4 of BIGH3 gene, which is responsible for Avellino corneal dystrophy. The use of the primer pair and probe according to the invention can diagnose Avellino corneal dystrophy in a more rapid and accurate manner than a conventional method that uses a DNA chip or PCR. | 2012-03-29 |
20120077201 | Methods and Compositions for Detecting a Drug Resistant EGFR Mutant - Development of acquired resistance to the therapeutic effects of an epidermal growth factor (EGFR) tyrosine kinase inhibitor in a patient that is suffering from a cancer is predicted by:
| 2012-03-29 |
20120077202 | Expression of FABP4 and Other Genes Associated with Bladder Cancer Progression - Disclosed are methods for predicting the risk of bladder cancer progression, including death from bladder cancer by determining gene expression levels of FABP4 and MBNL2 or other markers where increased levels correlate with lack of progression of the subject's bladder cancer, and decreased levels correlate with progression or death from bladder cancer, and/or determining gene expression levels of COL4A1, UBE2C, BIRC5, COL18A1, KPNA2, MSN, ACTA2, and/or CDC25B or other markers where increased levels correlate with progression of the subject's bladder cancer or death from it, and decreased levels correlate with lack of progression of bladder cancer. | 2012-03-29 |
20120077203 | REPORTER GENE CONSTRUCT, ASSAY KIT AND DETECTION METHOD - According to one embodiment, there is provided a reporter gene construct. The reporter gene construct comprises a transcriptional regulatory sequence and a reporter gene that is functionally bound to downstream of the transcriptional regulatory sequence. The reporter gene construct is activated dependently of environment and the reporter gene codes for a protein producible of producing a free radical by the | 2012-03-29 |
20120077204 | Detection of Protein Translocation by Beta-Galactosidase Reporter Fragment Complementation - Methods and compositions are provided for detecting molecular translocations, particularly protein translocations within and between sub-cellular compartments, using at least two components that exhibit a localization-dependent difference in complementation activity. In particular, alpha-complementing β-galactosidase fragments are provided. These β-galactosidase reporter fragments display significantly enhanced enzymatic activity when one fragment is localized in a membrane. Methods for carrying out no-wash ELISA assays based on the reporter component system are also provided. | 2012-03-29 |
20120077205 | METHOD FOR PRODUCING COMPLEX OF BIOTIN-LABELED CYPRIDINA (CYPRIDINA NOCTILUCA) LUCIFERASE WITH STREPTOAVIDIN AND METHOD FOR STABILIZING THE SAME - The present invention relates to a method for producing | 2012-03-29 |
20120077206 | Rapid Microbial Detection and Antimicrobial Susceptibility Testing - A method for the detection of microorganisms in a sample comprising contacting said sample with a biosensor concentration module, allowing microorganisms to grow for a first period of time and detecting growth of discrete microorganisms as an indication of the presence of said microorganisms. | 2012-03-29 |
20120077207 | CD86 and CD80 receptor competition assays - The present invention discloses a method for assaying the binding of L104EA29YIg to a receptor. The receptor is preferably CD86 or CD80. The present invention also discloses antibodies to be used in the assay, as well as hybridomas expressing the antibodies. | 2012-03-29 |
20120077208 | USE OF CARBAMOYL PHOSPHATE SYNTHETASE 1 (CPS) AS A HUMORAL BIOMARKER FOR THE DIAGNOSIS OF TUMOUR DISEASES AND CHRONIC INFLAMMATORY INTESTINAL DISEASES - The invention relates to the use of carbamoyl synthetase 1 (CPS 1) as a humoral biomarker in in vitro methods for early diagnosis and detection, progress prognosis, the evaluation of the severity, and the progress evaluation of tumor diseases and chronic inflammatory intestinal diseases. | 2012-03-29 |
20120077209 | PROTEIN BIOMARKERS AND THERAPEUTIC TARGETS FOR AUTOIMMUNE AND ALLOIMMUNE DISEAES - A method for characterizing the risk a subject will develop an autoimmune and/or alloimmune disease following tissue transplant includes obtaining a biological sample from the subject, wherein the subject has received the tissue transplant determining in the biological sample a level of at least one protein selected from Tables 1-4, comparing the measured level of the at least one protein to a control value, and characterizing a subject as at greater risk of developing an autoimmune disease and/or alloimmune disease if the level of at least one protein determined is increased or decreased compared to the control value. | 2012-03-29 |
20120077210 | Measuring G Protein Coupled Receptor Activation - The present invention relates to methods and polypeptides for detecting a compound in a sample. In particular, the present invention relates to the use of a cell-free composition comprising at least one G protein coupled receptor embedded in a lipid Mayer which when expressed in a cell the N-terminus of the G protein coupled receptor, or subunits thereof, is outside the cell and the C-terminus is inside the cell, and which is capable of binding the compound. Optionally, the composition also comprises at least one accessory molecule that directly or indirectly binds an intracellular loop and/or the C-terminus of the G protein coupled receptor. The G protein coupled receptor, and/or accessory molecule when present, in combination comprise a bioluminescent protein and an acceptor molecule, which enables bioluminescent resonance energy transfer (BRET) to be used to detect the compound binding the receptor. | 2012-03-29 |
20120077211 | STABLE COMPOSITIONS COMPRISING CHROMOGENIC COMPOUNDS AND METHODS OF USE - Compositions, assays, methods, and kits are disclosed for use in applications that utilize oxidation of a chromogenic electron donor such as diaminobenzidine (DAB) to generate a signal. Applications include, but are not limited to, immunohistochemistry, chromogenic in situ hybridization, Western blots, Northern blots, Southern blots, ELISA assays, and microarray detection. The compositions, assays, methods, and kits disclosed herein make use of a novel, stabilized formulation of DAB and a novel, stabilized formulation of hydrogen peroxide. | 2012-03-29 |
20120077212 | METHODS OF DIAGNOSING ALS - The invention relates to an epitope protection assay for use in diagnosis, prognosis and therapeutic intervention in diseases, for example, involving polypeptide aggregation, such as prion infections. The methods of the invention first block accessible polypeptide target epitope with a blocking agent. After denaturation of the polypeptide, a detecting agent is used to detect protein with target epitope that was inaccessible during contact with the blocking agent. The invention also relates to novel amyotrophic lateral sclerosis-specific epitopes and their uses to make antibodies, and to the novel antibodies and uses thereof. | 2012-03-29 |
20120077213 | CELL CULTURE IMPROVEMENTS - The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture. | 2012-03-29 |
20120077214 | Systems And Methods For Predicting Response To Minoxidil For The Treatment Of Androgenetic Alopecia - Methods, processes, systems, and apparatuses are disclosed for predicting minoxidil response in the treatment of androgenetic alopecia based on colorimetric assay. | 2012-03-29 |
20120077215 | METHODS AND COMPOSITIONS FOR THE DETECTION OF BETA-LACTAMASES - Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes. | 2012-03-29 |
20120077216 | Beta-Glucosidase Variants - The invention relates to recombinantly produced β-Glucosidase Variants with enhanced thermoactivity compared to naturally occurring proteins. The invention also provides methods for producing a variant β-glucosidase polypeptide with improved thermoactivity by identifying performance sensitive positions in a target β-glucosidase polypeptide and substituting the residue at that position with a thermoactivity enhancing residue. | 2012-03-29 |
20120077217 | BUFFY COAT TUBE AND FLOAT SYSTEM AND METHOD - A system for separating and axially expanding the buffy coat is provided that includes a flexible sample tube and a rigid separator float. The sample tube has a sidewall with a first cross-sectional inner diameter. The float includes a main body portion and one or more support members protruding from the main body portion. The float has a cross-sectional diameter less than that of the first cross-sectional inner diameter when the sample tube is expanded. The main body portion of the float and the sidewall define an annular volume therebetween. The support members traverse said annular volume to produce one or more analysis areas. During centrifugation, centrifugal force enlarges the diameter of the tube to permit density-based axial movement of the float. The centrifugal force is reduced to return the tube to its first diameter, thereby capturing the float and trapping the buffy coat constituents in the analysis area. | 2012-03-29 |
20120077218 | SICKLE CONFIRM MODIFIED HEMOGLOBIN SOLUBILITY TEST - The present invention provides a method for determining sickle-cell zygosity in a subject, comprising: forming a first solution comprising a sample from the subject, a phosphate buffer, a detergent, and a reducing agent; subjecting the first solution to centrifugation to form a second solution and a supernatant; taking a color reading of the supernatant and of the second solution; optionally filtering the second solution to form a filtrate and a precipitate, and optionally measuring the amount of the precipitation and the absorbance of the filtrate or taking a color reading of the filtrate. | 2012-03-29 |
20120077219 | VIBRATING MICROPLATE BIOSENSING FOR CHARACTERISING PROPERTIES OR BEHAVIOUR OF BIOLOGICAL CELLS - There is described a method of characterising a property or behaviour of at least one biological cell. The method comprises the steps of: providing a microplate; submerging at least one surface of the microplate in a cell culture medium such that at least one biological cell to be characterised is in contact with the microplate; vibrating the microplate; providing a plurality of mutually spaced sensors coupled to the microplate; obtaining a respective sensory data time series from each sensor during vibration of the microplate, the microplate and the sensors being arranged such that the obtained sensory data time series are not independent from one another; and processing the sensory data time series so as to characterise a property or behaviour of the at least one biological cell. A corresponding system for characterising a property or behaviour of at least one biological cell is also described. | 2012-03-29 |
20120077220 | HARVESTED SAMPLE PREPARATION PERSONAL BOX AND SYSTEM AND METHOD OF HARVESTED SAMPLE PREPARATION - A harvested sample preparation system includes an operation isolator | 2012-03-29 |
20120077221 | DETECTION DEVICE AND METHOD FOR DETECTING ANALYTE - There is provided a detection device that comprises a light source, a light sensor and an at least partially light-transmitting element that supports growth of at least one analyte selected from among fungi and bacteria. The light source, the at least partially light-transmitting element and the light sensor are positioned relative to one another and oriented relative to one another such that when the light source is illuminated, at least some of the light emitted from the light source passes through the at least partially light-transmitting element and is received by the light sensor. There is also provided a method of detecting an analyte, comprising illuminating a light source to emit light, and detecting an intensity of light that passes through an at least partially light-transmitting device that comprises an at least partially light-transmitting element that supports growth of at least one analyte selected from among fungi and bacteria. | 2012-03-29 |
20120077222 | Method and Device for Determining the Microbiological Contamination in an Environment - The method comprises providing at least one sampling plate and at least one supporting member in said environment with the supporting member being suitable for detachably receiving the sampling plate; and removing the plate from the supporting member after a period of time such that the microbiological contamination in said environment can be determined by analyzing said sampling plate. A device is provided for carrying out said method comprising the supporting member carrying one or more sampling plates, attaching means for detachably fixing the sampling plates therein and releasing means for removing of the sampling plate from the supporting member. | 2012-03-29 |
20120077223 | Method for single oxygen atom incorporation into peptides - Optimized enzymatic conditions incorporate a single oxygen atom into digested peptides using a peptidase. The incorporation of a single oxygen atom is especially useful for proteolytic | 2012-03-29 |
20120077224 | UNNATURAL AMINO ACID INCORPORATION IN EUKARYOTIC CELLS - This disclosure concerns compositions and methods for improving the incorporation of unnatural amino acids (UAAs) into proteins in eukaryotic cells. It is shown herein that mutation of a prokaryotic tRNA synthetase to increase the interaction with the corresponding tRNA anticodon region results in increased UAA incorporation efficiency in mammalian cells. | 2012-03-29 |
20120077225 | Melibiose operon expression system - New vectors expressible in a host comprising the promoter region of the melibiose operon operably linked to a transcriptional unit that includes nucleic acid sequence which is heterologous to the host. The expression of the nucleic acid sequence is controlled by the promoter region of the melibiose operon. The new vector can be used for the regulated heterologous expression of a nucleic acid sequence in a prokaryotic host. There is an isolated and purified nucleic acid sequence expressible in a host comprising the promoter region of the melibiose operon operably linked to a transcriptional unit that includes a nucleic acid sequence which is heterologous to the host. The expression of the nucleic acid sequence is controlled by the promoter region of the melibiose operon. A prokaryotic host is transformed with the vector or the isolated and purified nucleic acid sequence. There is a method for producing a polypeptide in a host using the vector. | 2012-03-29 |
20120077226 | SYNTHETIC GENES FOR PLANT GUMS AND OTHER HYDROXYPROLINE-RICH GLYCOPROTEINS - A new approach in the field of plant gums is described which presents a new solution to the production of hydroxyproline(Hyp)-rich glycoproteins (HRGPs), repetitive proline-rich proteins (RPRPs) and arabinogalactan-proteins (AGPs). The expression of synthetic genes designed from repetitive peptide sequences of such glycoproteins, including the peptide sequences of gum arabic glycoprotein (GAGP), is taught in host cells, including plant host cells. | 2012-03-29 |
20120077227 | Expression Process - An expression system for the production of a target polypeptide is provided. The expression system comprises an expression cassette comprising an inducible promoter operably linked to DNA encoding the target polypeptide and an expression cassette for over-expression of DNA binding transcriptional regulator protein, comprising a promoter operably linked to DNA encoding the DNA binding transcriptional regulator protein. The expression cassettes are under the control of orthogonal promoters. | 2012-03-29 |
20120077228 | OVEREXPRESSION OF AMINOACYL-tRNA SYNTHETASES FOR EFFICIENT PRODUCTION OF ENGINEERED PROTEINS CONTAINING AMINO ACID ANALOGUES - Methods for producing modified polypeptides containing amino acid analogues are disclosed. The invention further provides purified dihydrofolate reductase polypeptides, produced by the methods of the invention, in which the methionine residues have been replaced with homoallylglycine, homoproparglycine, norvaline, norleucine, cis-crotylglycine, trans-crotylglycine, 2-aminoheptanoic acid, 2-butynylglycine and allylglycine. | 2012-03-29 |